Thrilled to share our story in its final form! nature.com/articles/s41... 💥 After ~10 years, we show that BMAL1 represses transposons via chromatin regulation in embryonic stem cells—rather than circadian rhythms as in adult tissues.

My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...

SIRT7 regulates NUCKS1 chromatin binding to elicit metabolic and inflammatory gene expression in senescence and liver aging

Hi Bluesky community:) Our new manuscript is now available as a preprint!⛅️ biorxiv.org/content/10.1... 1/ Here, we describe a novel BMAL1-YAP complex in epidermal cells, which is hijacked during ageing to control the expression of up-regulated inflammation genes through enhancer binding.🧵

🌟 Excited to share that our latest preprint is now available! We’re one step closer to understanding the complex mechanisms behind ageing and inflammation. 👉 Read the preprint here: www.biorxiv.org/cgi/content/... Thank you to everyone who supported and believed in this project along the way!

🧪 ✍️ Please check out our new review on intercellular and interorgan communication between circadian clocks ⏰🧬 out today in Nature Reviews Molecular Cell Biology 🎉 @natrevmcb.bsky.social ! Here is the SharedIt link for free access: rdcu.be/d5ppE