Moesin prevents osteoclasts becoming too big, too fused & too destructive, maintaining healthy bone balance 📷 Ophélie Dufrançais et al Brigitte Raynaud-Messina @chrisverollet.bsky.social labs, University of Toulouse in @jcb.org ➡️ bpod.org.uk/archive/2026... with @antdlewis.bsky.social

Generating & growing blood vessel organoids from different stem cells – tools to study & trace vessels' heterogeneous pathways 📹 Sophie Guelfi et al @bergerslab.bsky.social VIB-KU Leuven Center for Cancer Biology in @science.org Advances ➡️ bpod.org.uk/archive/2026... with John Ankers

New approach using CAR T-cell therapy to stimulate intestine cell growth and repair 📷 Onur Eskiocak, Joseph Gewolb, Vyom Shah, James Rouse, Saria Chowdhury et al @amor-lab.bsky.social Beyaz Lab @cshlnews.bsky.social in @nataging.nature.com ➡️ bpod.org.uk/archive/2025... with @rooph.bsky.social

First Contact: Details revealed of cells & gene activity at the interface between mother & foetus using pig-derived organoids 📷 @crm110.bsky.social et al Coyne Lab @dukemedschool.bsky.social in @plosbiology.org ➡️ bpod.org.uk/archive/2025... with @antdlewis.bsky.social

Reference brain map as a resource for marrying neurobiology to complex biological systems data in a new model organism the clonal raider ant 📹 Dominic D. Frank & Lindsey E. Lopes et al @rockefeller.edu in @currentbiology.bsky.social ➡️ bpod.org.uk/archive/2025...

Enzymes that control formation of the structural polymer chitin in distinct sites of the fruit fly are not interchangeable 📷 Joan Bertran-Mas & @ettorephd.bsky.social et al @ibmb-csic.bsky.social in @plos.org Genetics ➡️ bpod.org.uk/archive/2025... with @antdlewis.bsky.social

New computer vision technology enhances freckle and skin lesion differentiation 📷 Yeong-Su Lim, Myeong Jin Ju & Hee-Jae Jeon et al Kangwon National University, Korea in @natureportfolio.nature.com Scientific Reports ➡️ bpod.org.uk/archive/2025... with @antdlewis.bsky.social

RNG2 protein is key for Toxoplasmosis parasite to be able to move, enter & leave host cells – possible treatment target Image made with @leicamicrosystems.bsky.social 📷 Romuald Haase & Bingjian Ren et al @soldatilab.bsky.social Uni of Geneva in @plosbiology.org ➡️ bpod.org.uk/archive/2025/12/26

Mouse pancreas epithelial cells with mutant RAS – have prominent nucleoli that sometimes arrange to make little smiley faces 📹 @zeinabrekad.bsky.social @oxfordbiochemistry.bsky.social. At the Dept's imaging facility Micron with @leicamicrosystems.bsky.social THUNDER ➡️ bpod.org.uk/archive/2025...

IMP1 regulates actin in microglia – nervous system immune cells – as they reorganise in response to challenge 📷 Josune Imaz-Iruretagoyena et al Achucarro Basque Center for Neuroscience in @plosbiology.org ➡️ bpod.org.uk/archive/2025... with @antdlewis.bsky.social

FAK Checker: Focal adhesion kinase (FAK) is key in controlling glioblastoma brain tumour stem cell energy usage 📷 Masalmeh Roza, @margaretframe.bsky.social et al Cancer Research UK Scotland Centre, @uoe-igc.bsky.social in and on @dmmjournal.bsky.social ➡️ bpod.org.uk/archive/2025...

Cell atlas of the dorsal vagal complex region of the brainstem that's involved in appetite sensing & metabolism reveals cellular complexity 📷 Cecilia Hes et al @mcgill.ca in @elife.bsky.social ➡️ bpod.org.uk/archive/2025... with @antdlewis.bsky.social

Complementary roles of Lmx1 (promoting proliferation) & Cdkn1b (limiting it) in orchestrating neural tube closure revealed in sea squirt Ciona 📹 Gabrielle Östlund-Sholars, Laurence A. Lemaire & Michael S. Levine @princeton.edu in @dev-journal.bsky.social ➡️ bpod.org.uk/archive/2025...

Healing of injured blood vessels is driven by gap junction protein connexin 43 at the wound edge 📷 Meghan W. Sedovy et al Scott Johnstone lab @fralinbiomed.bsky.social AJP Heart and Circulatory Physiology ➡️ bpod.org.uk/archive/2025... with @rooph.bsky.social

Analysing pancreatic cancer researchers establish a neuron–cancer–microenvironment interactome & propose denervating tumours as a new therapeutic pathway 📹 @verat-h.bsky.social, @simon-renders-md.bsky.social & Jasper Panten et al HI STEM Heidelberg in @nature.com ➡️ bpod.org.uk/archive/2025...

Bubbling Under: Artificial muscles driven by 10,000 microbubbles with targeted ultrasound activation 📹 Zhan Shi & Zhiyuan Zhang et al @ethz.ch in @nature.com ➡️ bpod.org.uk/archive/2025... with John Ankers

The lining of the heart & of the great veins join like a zip mediated by cadherin 6 which senses the heart's mechanical forces 📹 Moe Fukumoto et al National Cerebral & Cardiovascular Center Research Institute, Osaka in @cp-devcell.bsky.social cell.bsky.social ➡️ bpod.org.uk/archive/2025...

Conducting Labour: Proteins PIEZO1 & PIEZO2 of womb tissue & its neurons, translate mechanical forces into contractions in labour 📷 @yunxiao-dr.bsky.social et al Patapoutian lab @scripps.edu in @science.org ➡️ bpod.org.uk/archive/2025... with @rooph.bsky.social

Alterations called paroxysmal depolarizing shifts in neurons identified as a potential biomarker for seizure risk in brain tumour patients 📷 Bibi L. J. Bouwen et al Department of Neuroscience, Erasmus Medical Center, Rotterdam in @natcomms.nature.com ➡️ bpod.org.uk/archive/2025...

In Print: Nanofibre-based imaging to precisely replicate human skin details for eg forensic analysis & personalised medicine 📷 Tian Tian, Huixuan Han & Xinyi Lin et al Yangzhou University & Sun Yat-sen University in @natcomms.nature.com ➡️ bpod.org.uk/archive/2025... with John Ankers

Depicting their experiences post-venomous snakebite, children of the Amazon provide researchers with unique insights into how to improve care 📷 from Joseir Saturnino Cristino et al, Universidade do Estado do Amazonas, Brazil in @plos.org Neglected Tropical Diseases ➡️ bpod.org.uk/archive/2025...

Reappraisal of motor protein CENPE's role in bringing chromosomes together in preparation for accurate cell division 📷 @krunovuk.bsky.social & @ivatolic.bsky.social @institutrb.bsky.social in @natcomms.nature.com ➡️ bpod.org.uk/archive/2025... with John Ankers

Gastric organoids from patient tissue with & without tumours reveals complexities & influences of glycosylation patterns in health & disease 📷 Liliana Santos-Ferreira et al, @filipepts.bsky.social lab @i3suporto.bsky.social in @cp-cellreports.bsky.social ➡️ bpod.org.uk/archive/2025...

Details of how the bacteria-killing viruses bacteriophages are built - progress towards their wider medical usage 📷 James Hodgkinson-Bean et al Bostina lab @universityofotago.bsky.social Wolf lab @oistedu.bsky.social in @science.org Advances ➡️ bpod.org.uk/archive/2025... with @rooph.bsky.social

Thank you for featuring this beautiful image of a #zebrafish developing ovary from Amal’s recent work! 🐟🔬✨

Lab-grown long-term model system of egg development in zebrafish reveals mTOR-Stat3-Stathmin molecular pathway key for oocyte polarisation 📷 Amal Shawahny et al @yanivelkouby.bsky.social lab @hebrewuniversity.bsky.social in @currentbiology.bsky.social ➡️ bpod.org.uk/archive/2025...

Ya know when you see something online and you think “wait that looks familiar” 😆 thanks @bpodaily.bsky.social !

MAGIC – A new genetic engineering toolkit of plasmids for gene expression manipulation in vitro & in vivo Image made with @leicamicrosystems.bsky.social microscopy 📷 William B. Gillespie et al, @wythelab.bsky.social in @dev-journal.bsky.social ➡️ bpod.org.uk/archive/2025...

Probing miBrain: Patient-personalised, lab-grown brain model for studying disease & treatment 📹 @alicestanton.bsky.social & Adele Bubnys et al @mit.edu in @pnas.org ➡️ bpod.org.uk/archive/2025... with John Ankers

Sox and Eyes: Transcription factor SOX2's vital role revealed in driving neuron development as the eye's retina is formed 📷 Fuyun Bian, Kimiasadat Golestaneh, Emily Davis & Abdullah Khan et al @pittophthalmology.bsky.social in @dev-journal.bsky.social ➡️ bpod.org.uk/archive/2025...

Scaleable production of human stem cell-derived kidney organoids – utility confirmed by transplanting into kidneys in the lab 📷 Elena Garreta, Daniel Moya-Rull, Alberto Centeno & Andrés Marco et al @ibecbarcelona.eu in @natbiomedeng.nature.com ➡️ bpod.org.uk/archive/2025... with John Ankers

Pinpointing single molecules with a technique called motor-PAINT to analyse microtubule filament orientation & polarity at super resolution in developing neurons 📹 @mkiwanski.bsky.social et al Kapitein lab @utrechtuniversity.bsky.social in @jcellsci.bsky.social ➡️ bpod.org.uk/archive/2025...

Better Bait: 'Irresistible' sweaty sock scent traps black flies that spread the river blindness parasitic worm 📷 Louise Hamill of Sightsavers + Global Institute for Disease Elimination & MoHealth in Ghana, Côte d’Ivoire, Malawi & Mozambique ➡️ bpod.org.uk/archive/2025... with @rooph.bsky.social

Thanks so much for highlighting our images created with @rcollepardo.bsky.social

Mapping chromatin's structure at base-pair resolution reveals how it mediates cis-regulatory element interactions 📹 Hangpeng Li et al @jojdavies.bsky.social, MRC Molecular Haematology Unit, @imm.ox.ac.uk @ox.ac.uk in @cellpress.bsky.social ➡️ bpod.org.uk/archive/2025...

Enzyme Mos–MAPK acts as a switch between mitotic & meiotic cell division 📷 Ivan Avilov et al @plenart.bsky.social lab Max Planck Institute for Dynamics and Self-Organization, Göttingen in @jcb.org ➡️ bpod.org.uk/archive/2025... with @DrJohnAnkers

Key role for two proteins Esrp1/Esrp2 in pituitary & in cranio-facial development 📹 @shcarroll.bsky.social et al @childrensphila.bsky.social in @dev-journal.bsky.social ➡️ bpod.org.uk/archive/2025...

A 'micro-assault course' fibre scaffold for studying forces generated by cells as they behave & move 📹 @pierreucla.bsky.social et al @institutcurie.bsky.social Université PSL, Sorbonne Université in @pnas.org ➡️ bpod.org.uk/archive/2025... with John Ankers

Liver lobule zone molecular characteristics dictate susceptibility to WNT-driven liver cancer 📷 Alexander Raven et al @cruk-si.bsky.social in @nature.com ➡️ bpod.org.uk/archive/2025...

Head to Mosquitos: Cell atlas reveals sex differences in mosquitos – potentially applicable for disease spread management 📷 @oliviagoldman.net, AlexandraDefoe et al @rockefeller.edu in @cellpress.bsky.social ➡️ bpod.org.uk/archive/2025... with John Ankers

Nanoparticles mimicking a cell's own nucleosome DNA-packaging system developed in mice to deliver gene therapy for fibrotic lung disease 📹 Nan Kong & Dinghao Chen et al Westlake University, China in @science.org Advances ➡️ bpod.org.uk/archive/2025...

Fungi filaments have a growing tip & reabsorption behind: the protein actin drives this recycling Made with @leicamicrosystems.bsky.social microscopy 📷 by Marisa Delgado & Mario Pinar et al @cib-csic.bsky.social in @plos.org Genetics ➡️ bpod.org.uk/archive/2025... + @antdlewis.bsky.social

3D panoramic photoacoustic computed tomography (3DPanoPact) sees deep into living tissues without unwanted light scattering or limited field of view 📹Xuanhao Wang et al, Research Center for Computing Sensing, Zhejiang Lab, Hangzhou in @natcomms.nature.com ➡️ bpod.org.uk/archive/2025...

Silencing RAB23 gene associated with Carpenter syndrome confirms this genetic disorder as a ciliopathy 📷Wan Ying Leong & Catherine Hong Huan Hor et al, Hong Kong Baptist University & Duke-NUS Medical School in @plos.org Genetics ➡️ bpod.org.uk/archive/2025... with @antdlewis.bsky.social

Liver Little: Vascularisation developing in new-born mouse liver lobules contributes to determining the size of the organ at adulthood 📹 D. Berfin Azizoglu et al @hhmi.org @stanfordmedicine.bsky.social in @natcomms.nature.com ➡️ bpod.org.uk/archive/2025...

Silent Treatment: Anti-virulence therapeutic peptide EntV can spare healthy microbes when limiting harmful fungal biofilms 📷 Giuseppe Buda De Cesare et al University of Texas McGovern Medical School, Houston in @plos.org Pathogens ➡️ bpod.org.uk/archive/2025... with @antdlewis.bsky.social

Gut organ culture system as model to study microbial & neuronal signals finds these signals integrate to influence gut immunity & gut lining barrier defence 📷 Gitali Naim, Hadar Romano-Zadaka & Sivan Amidror et al @goodmanfaculty.bsky.social in @natcomms.nature.com ➡️ bpod.org.uk/archive/2025...

Nuclei numbers increase in proportion with volume as these fungal hyphae grow – the key to their protein-producing prowess? 📹 Ayaka Itani et al University of Tsukuba, Japan in @elife.bsky.social ➡️ bpod.org.uk/archive/2025... with John Ankers

Thanks for choosing my picture from our @jem.org paper for a biomedical picture of the day @bpodaily.bsky.social! It's always great to show the importance of the "other vessels"- the beautiful lymphatic system!

Membrane thickness variation among organelles measured via cryo-ET – a means to analyse how it affects their function 📹 @deglushk.bsky.social, Stefanie Böhm @becklab.bsky.social Max Planck Institute of Biophysics in @jcb.org ➡️ bpod.org.uk/archive/2025...