Alexandre Reynaud et al. from McGill Vision Research Unit investigate whether amblyopic patients have normal object size perception and how their perception is affected by abnormal interocular interactions. doi.org/10.1167/iovs.66.12.54

Elfride De Baere et al. from Ghent University find that a RPE65 variant p.(E519K) causes a novel dominant adult-onset maculopathy in 83 affected individuals. doi.org/10.1167/iovs.66.12.53

Cindy Karouta et al. from the University of Canberra find that methylphenidate inhibits the development of myopia by altering dopamine and norepinephrine reuptake. doi.org/10.1167/iovs.66.12.52

Sabine Kling et al. from the University of Bern validate an existing finite element model for predicting the flattening effect of corneal cross-linking in a clinical scenario and use it to investigate parameters that most influence CXL-induced flattening doi.org/10.1167/iovs.66.12.51

Yun Xie et al. from Shanghai Minhang District Hospital evaluate the therapeutic efficacy of kaempferol (KAE), a bioactive flavonoid with demonstrated antioxidant and anti-inflammatory properties and explore the underlying molecular mechanisms. doi.org/10.1167/iovs.66.12.50

Rachel S. Chong et al. from Singapore Eye Research Institute investigate associations among intraocular pressure (IOP), axial length (AXL), and optic nerve head (ONH) characteristics in highly myopic eyes. doi.org/10.1167/iovs.66.12.49

Yangfan Yang et al. from Zhongshan Ophthalmic Center investigated the antifibrotic effects of human bone marrow mesenchymal stem cell-derived (hBMMSC) sEVs on TM cells in two-dimensional/three-dimensional cultures in vitro and in vivo. doi.org/10.1167/iovs.66.12.48

Veluchamy A. Barathi et al. from Singapore Eye Research Institute investigate how pigmentation heritage affects susceptibility to form deprivation myopia through crossbreeding myopia-susceptible albino and myopia-resistant pigmented guinea pigs. doi.org/10.1167/iovs.66.12.47

Ruifang Sui et al. from Peking Union Medical College Hospital find that exon skipping therapy restores ciliary function in USH2A-related retinal degeneration. doi.org/10.1167/iovs.66.12.46

Sharon Gerecht et al. from Duke University examine VEGF receptor 2 signaling in endothelial–pericyte interactions, highlighting VEGFR2 as a potential therapeutic target for promoting pericyte coverage and decreasing vascular leakage in diseased retinas. doi.org/10.1167/iovs.66.12.45

Xialin Liu, Chang He et al. from Zhongshan Ophthalmic Center target RPE senescence via suppressing IL-6/IL-6R signaling for treating retinal degenerative diseases. doi.org/10.1167/iovs.66.12.44

Feng Pan et al. from The Hong Kong Polytechnic University investigate the role of the gap junction subunit connexin 36 (Cx36) in mediating secondary cell death and its impact on the apoptosis of retinal ganglion cells (RGCs) following ocular alkali burns. doi.org/10.1167/iovs.66.12.43

Huiling Li et al. from The Second Xiangya Hospital find that LINC02099 promotes retinal extracellular matrix deposition in diabetic mice via the miRNA-214-3p/CTSS axis. doi.org/10.1167/iovs.66.12.42

Glenn Yiu et al. from the University of California, Davis @ucdavis investigate systemic and local lipids in nonhuman primates with drusen and age-related maculopathies. doi.org/10.1167/iovs.66.12.41

Simon W. M. John et al. from Columbia University Irving Medical Center report an absence of glaucoma in Tg-MYOCY437H mice of diverse genetic backgrounds. doi.org/10.1167/iovs.66.12.40

Yusen Huang et al. from Qingdao Yusen Eye Hospital find that pre-colonization of cacillus siamensis on ocular surface mitigates fusarium keratitis through direct antifungal activity and pre-activation of the NF-κB pathway. doi.org/10.1167/iovs.66.12.38

Bilal Haj Najeeb et al. from the Medical University of Vienna report the global distribution of macular neovascularization type 3 and redefine the associated burden of neovascular age-related macular degeneration. doi.org/10.1167/iovs.66.12.37

New article in the Myopia issue bit.ly/4nsOVWc by Mark A. Bullimore et al. reviews the latest on interventions for controlling myopia onset and progression. doi.org/10.1167/iovs.66.12.39

Clement C. Tham, Poemen P. Chan et al. from The Chinese University of Hong Kong synthesize and evaluate the quality of evidence from existing meta-analyses on ocular and systemic factors and biomarkers associated with primary glaucoma. doi.org/10.1167/iovs.66.12.35

Stuart K. Gardiner et al. from Devers Eye Institute identify relations between pulsatility in the optic nerve head or peripapillary retinal vessels and the rate of progression in glaucoma. doi.org/10.1167/iovs.66.12.34

Yongqing Liu, Douglas Dean et al. from the University of Louisville characterize Zeb1 regulation of nitrogen mustard (NM)–induced acute corneal epithelial damage and its recovery in mice. doi.org/10.1167/iovs.66.12.33

Ming-Ming Yang et al. from Shenzhen People's Hospital use integrative multiomics to identify CD64⁺ monocytes as potential contributors to Age-Related Macular Degeneration. doi.org/10.1167/iovs.66.12.32

ulie C. Lim et al. from the University of Auckland investigate changes in redox balance and mitochondrial activity in the retinas of cystine/glutamate antiporter knockout mice. doi.org/10.1167/iovs.66.12.31

Omar A. Mahroo et al. explore whether nyctalopia in vitamin A deficiency (VAD) is attributable to simple reduction in quantal catch or to an “equivalent background” phenomenon. doi.org/10.1167/iovs.66.12.30

Yang Yang et al. from Sichuan University find that RP1 dual-AAV gene therapy preserves retinal structure and ameliorates photoreceptor degeneration in a murine model of retinitis pigmentosa. doi.org/10.1167/iovs.66.12.29

Jeremy Whitson et al. from High Point University perform proteomic characterization of the rhesus macaque lens nucleus. doi.org/10.1167/iovs.66.12.28

New digest article in the IMI issue bit.ly/4gfVbhE by Nina Tahhan et al. delivers targeted updates in developing areas identified for revision since the previous digest. doi.org/10.1167/iovs.66.12.27

Daniel X. Hammer et al. from the U.S. Food and Drug Administration quantify normative human choriocapillaris measures across the macula. doi.org/10.1167/iovs.66.12.26

Juliette E. McGregor et al. from the University of Rochester Medical Center @UR_Med find that inner limiting membrane peel extends in vivo calcium imaging of retinal ganglion cell activity beyond the fovea in non-human primates. doi.org/10.1167/iovs.66.12.25

Laura E. Downie et al. from the University of Melbourne describe altered corneal T-cell motility and sensory nerve features in older adults with human immunodeficiency virus infection. doi.org/10.1167/iovs.66.12.23

Jing Han et al. from Tangdu Hospital explore the causal links between antihypertension drugs usage and age-related macular degeneration. doi.org/10.1167/iovs.66.12.24

New article in the Nystagmus issue bit.ly/4pxbJX1 by Mervyn Thomas et al. from the University of Leicester defines the genetic architecture of foveal morphology and explores its relevance to foveal hypoplasia. doi.org/10.1167/iovs.66.12.22

Damon Wong, Marcus Ang et al. from Singapore Eye Research Institute investigate the focal relationship between choroidal thickness and retinal sensitivity in myopic eyes. doi.org/10.1167/iovs.66.12.21

Nan-Kai Wang et al. from Columbia University Irving Medical Center characterize a no b-wave (nob) mouse model of congenital stationary night blindness (CSNB) caused by a Grm6 variant that disrupts photoreceptor-to-bipolar cell signaling. doi.org/10.1167/iovs.66.12.20

Abdullah Ağın et al. from Haseki Training and Research Hospital assess the reflectivity of the outer retinal layers in patients with central serous chorioretinopathy & find the relationship between the dimensions of the subretinal fluid & ORL doi.org/10.1167/iovs.66.12.19

Martin-Paul Agbaga et. al from Dean McGee Eye Institute investigate tropism and retinal transduction sfficiency of adeno-associated virus serotypes in mice. doi.org/10.1167/iovs.66.12.18

Juan Ye et al. from Zhejiang University use 3 indicators, body roundness index, lipid accumulation product, and visceral adiposity index, to investigate the longitudinal relationship between visceral obesity and DR doi.org/10.1167/iovs.66.12.17

Deepak Shukla et al. from the University of Illinois Chicago find that antagonizing viral MicroRNAs reduces ocular HSV-1 pathogenesis and enhances mucosal immune homeostasis. doi.org/10.1167/iovs.66.12.16

Yali Jia et al. from Casey Eye Institute quantify choriocapillaris flow deficits using projection-resolved optical coherence tomographic angiography and evaluate whether they are correlated with diabetic retinopathy. doi.org/10.1167/iovs.66.12.13

Deena Elul, Ayelet McKyton & Netta Levin from The Hebrew University of Jerusalem investigate temporal sensitivity under photopic and scotopic conditions across the cortical visual hierarchy. doi.org/10.1167/iovs.66.12.12

Juan Yang, Alexandra Bernardo-Colón & S. Patricia Becerra @NatEyeInstitute find that lack of Pnpla2 accelerates progression of AMD-Like features in mice. doi.org/10.1167/iovs.66.12.11

Olavi Pärssinen et al. from the University of Jyväskylä determine the prevalence of myopia among Finnish conscripts and identify factors associated with its occurrence in Finland. doi.org/10.1167/iovs.66.12.10

Vikas Gulati et al. from Truhlsen Eye Institute report the changes in aqueous humor dynamics (AHD) and biometric parameters associated with growth and maturation in male Dutch-belted rabbits. doi.org/10.1167/iovs.66.12.9

Maxman Mainali et al. from Boise State University find that lipid and cholesterol peroxidation leads to α-crystallin membrane aggregation and cataract formation. doi.org/10.1167/iovs.66.12.8

Xingtao Zhou, Jing Zhao et al. from Fudan University use a mouse model of granular corneal dystrophy Type II to reveal impaired autophagy and recapitulates human pathogenesis. doi.org/10.1167/iovs.66.12.7

Joseph L. Demer & Robert A. Clark investigate functional anatomy of ocular counter-rolling in superior oblique palsy. doi.org/10.1167/iovs.66.12.6

Paolo Melillo et al. from the University of Campania Luigi Vanvitelli investigate the prevalence of cystoid macular edema in relation to the disease-causing genes in a large cohort of genetically defined patients with non-syndromic retinitis pigmentosa. doi.org/10.1167/iovs.66.12.5

Claire-Marie Dhaenens et al. from University of Lille investigate bestrophin-1 structure & function with the aim of assessing the pathogenicity of variants reported in the Leiden Open Variation Database and in a large French cohort of bestrophinopathies. doi.org/10.1167/iovs.66.12.4

Chen-Wei Pan et al. from Suzhou Medical College of Soochow University investigate the association between plasma levels of omega-3 fatty acids and the risk of POAG. doi.org/10.1167/iovs.66.12.3

Dae-Won Kim et al. from Yonsei University dentify the expression of Nkx3.2 in retinal pigment epithelium (RPE) and evaluate its physiological role in association with retinal degeneration. doi.org/10.1167/iovs.66.12.2