Emilio Lecona
@emlecona.bsky.social
📤 417
📥 454
📝 167
Y escurriendo la pasta, y entrando al autobús cuando llueve...
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about 8 hours ago
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Emilio Lecona
The EMBO Journal
about 17 hours ago
Deadlines are approaching for
@keystonesymposia.bsky.social
#Ubiquitin
Family Biology & Disease, this February in Banff! See scholarship, abstract and discount reg dates:
keysym.us/KSUbiquitin26
#KSUbiquitin26
Your chance to meet our editor
@hvodermaier.bsky.social
& discuss your work with him!
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The Ubiquitin Family in Biology and Disease | Keystone Symposia
Join us at the Keystone Symposia on The Ubiquitin Family in Biology and Disease, February 2026, in Banff, with field leaders!
https://keysym.us/KSUbiquitin26
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Emilio Lecona
We are looking for a candidate to apply for a postdoctoral contract in the Juan de la Cierva 2025 call, to join our lab at the
@cbm-csic-uam.bsky.social
to work on the interplay between the ubiquitin pathway, DNA replication and the replication stress response.
#JDC2025
4 days ago
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Emilio Lecona
Centro de Biología Molecular Severo Ochoa
5 days ago
📢¡Oferta de trabajo en el CBM! El grupo de César Cobaleda busca postdoc para estudiar cómo se origina la leucemia infantil (B-ALL). 💡 Proyecto “la Caixa” Research Health 2025 🧬 Modelos murinos, epigenética, célula única 📅 Deadline: 5 dic 2025
www.cbm.uam.es/index.php/jo...
@cjchcm.bsky.social
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Molecular Mechanisms of Childhood Leukemia Development - Centro de Biología Molecular Severo Ochoa
Job Description We are seeking a highly motivated postdoctoral researcher to join our laboratory to study the early steps of development of childhood B-cell Acute Lymphoblastic Leukemia (B-ALL). The p...
https://www.cbm.uam.es/index.php/job/cellular-plasticity-in-development-and-cancer-unit-at-centro-de-biologia-molecular-severo-ochoa-cbm-madrid-full-time-es-molecular-mechanisms-of-childhood-leukemia-development/?lang=es
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We are looking for a candidate to apply for a postdoctoral contract in the Juan de la Cierva 2025 call, to join our lab at the
@cbm-csic-uam.bsky.social
to work on the interplay between the ubiquitin pathway, DNA replication and the replication stress response.
#JDC2025
4 days ago
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Emilio Lecona
Jorge Martínez-Cano
5 days ago
🚨 We’re hiring a Postdoc! 🧬 Join us at the Centro de Biología Molecular
@cbm-csic-uam.bsky.social
(CBM, Madrid) to explore the molecular mechanisms driving childhood B-ALL. 2-year contract (possible 3rd-year extension) Start: end of 2025 / beginning of 2026 Deadline: 5th December 2025
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Emilio Lecona
Centro de Biología Molecular Severo Ochoa
5 days ago
El dossier de la revista SEBBM de este mes, ¡dedicado a nuestro cincuentenario! 🤩🌟🎉
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Emilio Lecona
Harmit Singh Malik
6 days ago
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on. (Please repost to reach a broad audience.)
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Emilio Lecona
Sociedad Española de Bioquímica y Biología Molecular (SEBBM)
6 days ago
🎉 ¡Celebramos 50 años del
@cbm-csic-uam.bsky.social
! Un referente en investigación biomolecular en España, con más de 500 científicos. 🔬💡 Lee más:
https://f.mtr.cool/okvytqqxpc
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Emilio Lecona
6 days ago
The 21st Course on Epigenetics which will take place from March 25th to April 1st, 2026 at the Institut Curie (Paris). The Course is open to M2 and PhD students. Application via the Advanced Training Office website before December 15th, 2025 at:
minilien.curie.fr/3avv47
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Epigenetics - 21st Course on Epigenetics 2026: Towards a quantitative understanding of nuclear dynamics during development and diseases | Institut Curie Advanced Training
The aim of this course is to provide an overview of epigenetic mechanisms and their links to gene expression and chromatin dynamics, in different systems. The diverse functions of the nucleus involvin...
http://minilien.curie.fr/3avv47
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Emilio Lecona
Jose A. Esteban
7 days ago
Como describe Ginés Morata: "Antonio García-Bellido fue uno de los muy pocos pioneros científicos que ha producido España”.
elpais.com/ciencia/2025...
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Muere Antonio García-Bellido, descubridor de las fronteras invisibles dentro de los seres vivos
El biólogo, fallecido a los 89 años, deja un legado científico que roza las alturas de los nobeles Santiago Ramón y Cajal y Severo Ochoa
https://elpais.com/ciencia/2025-11-11/muere-antonio-garcia-bellido-descubridor-de-las-fronteras-invisibles-dentro-de-los-seres-vivos.html?ssm=bsky_CC
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Emilio Lecona
Guillermo Peris 🧬💻
8 days ago
What Rosalind Franklin truly contributed to the discovery of DNA’s structure.
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What Rosalind Franklin truly contributed to the discovery of DNA’s structure
Franklin was no victim in how the DNA double helix was solved. An overlooked letter and an unpublished news article, both written in 1953, reveal that she was an equal player.
https://www.nature.com/articles/d41586-023-01313-5
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Emilio Lecona
Andrew Deans
8 days ago
🧬 List of 2026 DNA repair and genome stability conferences, now updated. Please let me know if there is anything missing!
docs.google.com/spreadsheets...
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DNA REPAIR/GENOME STABILITY CONFERENCES
https://docs.google.com/spreadsheets/d/1SuEjBNY5ckO-TgOQAcq7afSl4TPoSCgZxC9IpmCKv4k/edit?usp=sharing
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Emilio Lecona
Centro de Biología Molecular Severo Ochoa
11 days ago
Escuchar a Alfonso Valencia hoy en el CBM ha sido una oportunidad para reflexionar sobre el futuro de la biología. Su visión desde el Barcelona Supercomputing Centre
@bsc-cns.bsky.social
mostró cómo la integración entre IA, datos masivos y biología está redefiniendo la investigación.
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Emilio Lecona
Harmit Singh Malik
10 days ago
When people celebrate the individual genius of folks in science, they should also mourn the collective loss of genius of folks who were actively discouraged or disadvantaged from a career in science because of the same person(s)
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Emilio Lecona
Celeste Labedz
10 days ago
In case anyone is wondering if Watson was really THAT bad,
@lpachter.bsky.social
compiled a list of quotes that are absolutely not for the faint of heart.
liorpachter.wordpress.com/2018/05/18/j...
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Emilio Lecona
Sociedad Española de Bioquímica y Biología Molecular (SEBBM)
11 days ago
Queridos y queridas colegas, es un verdadero honor invitaros al 48º Congreso Internacional de la Sociedad Española de Bioquímica y Biología Molecular (SEBBM), que celebraremos en la ciudad de Tarragona del 7 al 10 de septiembre de 2026. ¡Reservad vuestras fechas!
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Emilio Lecona
Marcin J. Suskiewicz
13 days ago
SUMO interactions: the 1st of two reviews which Aanchal (
@origichals.bsky.social
), El Hadji, and I have recently written on non-covalent interactions of SUMO is now out. The 1st covers interactions with E1, E2, and deSUMOylating enzymes; the 2nd - on interactions with SIMs etc. - will appear soon.
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Non-covalent SUMO interactions with (de)conjugation enzymes
SUMOylation – a protein post-translational modification (PTM) related to ubiquitylation – involves the reversible covalent attachment of the small ubiquitin-like modifier (SUMO) to proteins. During th...
https://portlandpress.com/essaysbiochem/article/doi/10.1042/EBC20253038/236724/Non-covalent-SUMO-interactions-with-de-conjugation
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Emilio Lecona
Anne Carpenter
13 days ago
Required reading for cell biologists to get a sense of basic statistical principles!
www.nature.com/articles/s41...
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Ten essential tips for robust statistics in cell biology - Nature Cell Biology
Statistical thinking is a core part of solid, trustworthy biology. However, many studies still include insufficient sample sizes, have poor experimental design or select an incorrect statistical metho...
https://www.nature.com/articles/s41556-025-01801-y
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Emilio Lecona
Centro de Biología Molecular Severo Ochoa
17 days ago
Mil gracias a Julia Otero y todo el equipo de
@juliaenlaonda.bsky.social
por contar a vuestra audiencia lo que hacemos en el CBM, lo que llevamos haciendo 50 años siguiendo la estela de Severo Ochoa. ¡Por otros cincuenta años más del CBM y de
#JELO
!
@ondacero.es
@csic.es
@uam.es
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Emilio Lecona
Numbereightball
18 days ago
Never forget
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Very interesting!
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19 days ago
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Emilio Lecona
Eric Topol
20 days ago
What do the naked mole rat and bowhead whale (lives to ~200 years) have in common to explain their remarkable longevity? Enhanced DNA repair
www.nature.com/articles/s41...
erictopol.substack.com/p/a-long-awa...
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Evidence for improved DNA repair in long-lived bowhead whale - Nature
Analysis of the longest-lived mammal, the bowhead whale, reveals an improved ability to repair DNA breaks, mediated by high levels of cold-inducible RNA-binding protein. &nbs...
https://www.nature.com/articles/s41586-025-09694-5
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Congrats!
21 days ago
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Emilio Lecona
The EMBO Journal
22 days ago
H2B ubiquitination by RNF20/40 safeguards replication fork dynamics in human cells, by facilitating fork reversal and recruiting RNF169 that protects from excessive degradation of nascent DNA
@penengolab.bsky.social
and collaborators
www.embopress.org/doi/full/10....
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Emilio Lecona
Mark Hamill
22 days ago
I have a very bad feeling about this...
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Emilio Lecona
Pedro Torrijos
22 days ago
En Viena hay seis torres nazis de hormigón: colosales, indestructibles. Fueron fortalezas antiaéreas, pero hoy son acuarios o miradores. Porque la ciudad ha entendido lo que hacer con su pasado: transformar la máquina de guerra en memoria. Os lo cuento en
#LaBrasaTorrijos
🧵⤵️
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Emilio Lecona
The EMBO Journal
22 days ago
What specific targets & roles are there for all distinct polyubiquitin chain types? Niels Mailand, Robert Shearer et al profile a panel of
#ubiquitin
replacement cell lines, implicating K29 chains in chromatin regulation via SUV39H1 destabilization
www.embopress.org/doi/full/10....
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Emilio Lecona
The Batlle Lab
25 days ago
🧵1/17 📣Thrilled to share our latest study just out in Cancer Discovery! ➡️
aacrjournals.org/cancerdiscov...
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A plastic EMP1⁺ to LGR5⁺ cell state conversion as a bypass to KRAS-G12D pharmacological inhibition in metastatic colorectal cancer
Abstract. Inhibitors of the oncogene KRAS hold promise for treating metastatic CRC (mCRC). Here we show that a selective, covalent small molecule inhibitor of the active (ON) conformation of RAS-G12D,...
https://aacrjournals.org/cancerdiscovery/article/doi/10.1158/2159-8290.CD-25-0679/766696/A-plastic-EMP1-to-LGR5-cell-state-conversion-as-a
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Emilio Lecona
Nilsson lab
26 days ago
I have a PhD opening in my lab for an exiting project using base editor screens to find novel drug targets. Please help spread the word.
candidate.hr-manager.net/ApplicationI...
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PhD student position in the Cell Signaling and Cell Cycle group at the Danish Cancer Institute.
The Cell Signaling and Cell Cycle group, headed by Prof. Jakob Nilsson, is looking for a highly motivated and enthusiastic PhD student to establish novel CRISPR
https://candidate.hr-manager.net/ApplicationInit.aspx?cid=1572&ProjectId=145533&DepartmentId=18958&MediaId=5&SkipAdvertisement=False
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Emilio Lecona
Eva Petermann
28 days ago
A follow-up PhD project is now available:
www.findaphd.com/phds/project...
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Y después de la ciencia, se disfruta un poco de Sevilla.
about 1 month ago
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Great workshop!
add a skeleton here at some point
about 1 month ago
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Emilio Lecona
xandasbolas8 #7291 🏳️⚧️🏳️🌈🍉
about 1 month ago
Hasta el 85 funcionó. Hasta 1985.
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Patronato de Protección a la Mujer: un reformatorio franquista para lesbianas que funcionó en democracia
La lucha de su viuda logra que el Gobierno reconozca por primera vez como víctima de la dictadura a una mujer que fue recluida en centros religiosos de 1978 a 1985
https://elpais.com/espana/galicia/2025-10-16/patronato-de-proteccion-a-la-mujer-un-reformatorio-franquista-para-lesbianas-que-funciono-en-democracia.html?ssm=bsky_CC
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Emilio Lecona
Sacha Coward
about 1 month ago
Let me tell you a story about how a 17th century painter accidentally made one of the most powerful pieces of intersex representation in art, whilst (probably) trying to make an offensive joke for horny nerds...
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Emilio Lecona
Patricia Fernández de Lis
about 1 month ago
Y hoy, en Viva la ciencia: Una terapia experimental salva la vida de más de medio centenar de niños con una enfermedad letal
elpais.com/ciencia/2025...
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Una terapia experimental salva la vida de más de medio centenar de niños con una enfermedad letal
El tratamiento, que se administra una sola vez y listo, ha permitido que la niña Eliana Nachem, encerrada en su casa para evitar infecciones, salga al mundo
https://elpais.com/ciencia/2025-10-15/una-terapia-experimental-salva-la-vida-de-mas-de-medio-centenar-de-ninos-con-una-enfermedad-letal.html
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Emilio Lecona
Aga Gambus
about 1 month ago
To explain - the appointed candidate (including EU/international candidates) can do a PhD as a "staff member" upon paying a small fee. People not interested in doing PhD are of course also invited to apply :). Please share.
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Emilio Lecona
Aga Gambus
about 1 month ago
Fully-funded 4-years competitive PhD project in our lab (MIBTP-doctoral-training-programme. p97 unfoldase functions during DNA replication. Open to UK/international candidates. Please get in touch for informal enquiries. Deadline 27th of November. Please share.
warwick.ac.uk/fac/cross_fa...
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Professor Aga Gambus
Professor Aga Gambus
https://warwick.ac.uk/fac/cross_fac/mibtp/phd/supervisors/AGambus/#unfoldase_structure
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Emilio Lecona
Pedro Torrijos
about 1 month ago
Esto redondo que tengo detrás en el video no es una galería de arte ni una casa. Es, oficialmente, el país más pequeño del mundo. Se llama Kugelmugel, y está en medio del Prater de Viena. Su historia, aviso, parece una broma muy elaborada, pero es completamente real: 🧵⤵️
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Emilio Lecona
Andrew Deans
about 1 month ago
Ever wondered what S-phase tastes like? 3 lucky presenter prize winners will find out (+Amazon voucher!) at
#ACDTM25
. You can still register for this fantastic Melbourne meeting Oct 20-22. Official 10 year old taste tester: "lemon excision repair" is the best flavour
www.australiancellcycle.org
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Emilio Lecona
CortésLab
about 1 month ago
Kickstarting our Bluesky🦋 account with great news! Our REPAIRome study finally out today in
@science.org
www.science.org/doi/10.1126/...
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A comprehensive genetic catalog of human double-strand break repair
The analysis of DNA sequence outcomes provides molecular insights into double-strand break (DSB) repair mechanisms. Using parallel in-pool profiling of Cas9-induced insertions and deletions (indels) w...
https://www.science.org/doi/10.1126/science.adr5048
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Emilio Lecona
Ana Conesa
about 2 months ago
Looking for scientists working with long-read transcriptomics technologies to join a COST action proposal. Contact us!!!
@nanoporetech.com
@pacbio.bsky.social
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Emilio Lecona
Numeritos 🍕🏳️🌈🏳️⚧️🇵🇸
about 2 months ago
Os cuento una situación habitual que he vivido hoy con mis hijas, pero que por algunos detalles me parece llamativa. Íbamos en el bus camino al colegio, mis hijas (5 y 7) estaban jugando entre ellas. En una parada ha subido una amiga de la pequeña, con su madre y su hermano gemelo.
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Emilio Lecona
Centro de Biología Molecular Severo Ochoa
about 2 months ago
🎥🔬 50 años descodificando la vida. Descubre en este video cómo el CBM ha marcado la biomedicina en España y el mundo, formando talento y generando ciencia de impacto.
#CincuentenarioCBM
#DecodingLife
youtu.be/7bzJOIW5kyM
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Cincuentenario del Centro Biología Molecular Severo Ochoa - Decoding life
YouTube video by Centro de Biología Molecular Severo Ochoa
https://youtu.be/7bzJOIW5kyM
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Emilio Lecona
Centro de Biología Molecular Severo Ochoa
about 2 months ago
🎨🔬 ¡La ciencia también se puede contemplar! Durante el Golden Jubilee Symposium del CBM inauguramos nuestra exposición de imágenes científicas, que muestra la belleza de la investigación. Desde microbiología, virología hasta metabolismo y estabilidad genómica
#CincuentenarioCBM
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Un placer y un privilegio participar en esta mesa redonda, rodeado de grandes científicos y celebrando los 50 años del
@cbm-csic-uam.bsky.social
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about 2 months ago
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Scientists reflected on running DNA.
about 2 months ago
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Emilio Lecona
Lori Passmore
about 2 months ago
We have an open post-doc position in my group to study mRNA cleavage and polyadenylation using biochemical reconstitution and cryoEM. Please get in touch if you are interested in joining this amazing team! 🔬🧬🤩
#RNA
#cryoEM
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Emilio Lecona
Tabernita
about 2 months ago
Buenas, cuánta gente de aquí tiene una higuera?? Se está haciendo un estudio en la USC y piden nuestra ayuda. Las quieren de donde sea, Galicia, España y Europa. Yo le mandaré de la mía y posiblemente de algún vecino (si me dejan). Animaos vosotros también
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Emilio Lecona
Prasad Jallepalli, MD, PhD
about 2 months ago
in retrospect, it was a mistake to teach algebra and geometry but not "statistics for everyone" in high school we are drowning in lies, partly because we never learned to swim
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