Artem Nemudryi
@artemnemudryi.bsky.social
📤 71
📥 144
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Assistant Professor at University of Florida College of Medicine
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First preprint from the Nemudryi Lab! 🍾 In this work, we link antiviral immunity in bacteria and humans by showing that homologs of human Schlafen nucleases protect bacteria from phages.
www.biorxiv.org/content/10.1...
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Bacterial Schlafens mediate anti-phage defense
Human Schlafen proteins restrict viral replication by cleaving tRNA, thereby suppressing protein synthesis. Although the ribonuclease domain of Schlafen proteins is conserved across all domains of lif...
https://www.biorxiv.org/content/10.1101/2025.07.24.666596v1
2 months ago
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👇🏽👇🏽👇🏽
add a skeleton here at some point
about 1 month ago
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First preprint from the Nemudryi Lab! 🍾 In this work, we link antiviral immunity in bacteria and humans by showing that homologs of human Schlafen nucleases protect bacteria from phages.
www.biorxiv.org/content/10.1...
loading . . .
Bacterial Schlafens mediate anti-phage defense
Human Schlafen proteins restrict viral replication by cleaving tRNA, thereby suppressing protein synthesis. Although the ribonuclease domain of Schlafen proteins is conserved across all domains of lif...
https://www.biorxiv.org/content/10.1101/2025.07.24.666596v1
2 months ago
3
50
30
reposted by
Artem Nemudryi
Aude Bernheim
2 months ago
🦠🧍♀️From bacterial to human immunity. We report in
@science.org
the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity. Co-led wt
@enzopoirier.bsky.social
by D. Bonhomme and
@hugovaysset.bsky.social
www.science.org/doi/10.1126/...
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https://www.science.org/doi/10.1126/science.adr8536
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