🎉 After a very long one (appropriately…), I’m excited to share work revealing an unexpected role for the epigenetic regulator ZFP57 - linking development, lactation, milk composition and lifelong health. Check it out: www.nature.com/articles/s41... #MammaryGlandBiology #DOHaD

Congrats @retrogenomics.bsky.social! Richly deserved.

Our new preprint on SMCHD1! We’ve shown SMCHD1’s ATPase activity is critical for function in vivo, and excitingly a new DNA binding domain neighbouring the ATPase domain activates the enzymatic function, which is important for normal chromatin binding. urldefense.com/v3/__https:/...

New paper from my lab out in NAR. We found that young L1 elements are controlled by SETDB1 and H3K9me3 in human neural progenitor cells via a mechanism independent of HUSH and TRIM28/KZNFs. academic.oup.com/nar/article/...

🧪 My lab has an opening for a postdoc position soon! Please share/get in touch!

Registrations are now OPEN! Join us in Newcastle for the “RNA in Physiology and Disease” conference, an international meeting bringing together world-leading RNA biologists and emerging researchers. Early bird deadline: 1 May Abstract deadline: 30 June Register now: genetics.org.uk/events/rna-i...

New preprint from the lab! We dig into the regulatory roles of TEs in the mouse placenta, with some surprising findings. Led by the awesome @smamante.bsky.social. Particular kudos to him for navigating the many twists and turns of the project.

So depressing and hilarious in equal measures. "A case study with pregnant mathematicians and aspiring gynecologists demonstrates that integrating the Fibonacci sequence into labor progression charts induces spontaneous appreciation for abstract algebra and mild cravings for prime numbers." 🤣

OOOOH Researchfish Is going extinct 🐡🐟🐠 help.researchfish.com/en_US/resear...

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The names of 72 female scientists will be added to the Eiffel Tower, to accompany those of 72 male scientists that are already engraved there tinyurl.com/e2satnyp 👏👩‍🔬 🧪

Open postdoc position in our lab @icr.ac.uk to develop a cfDNA test for #early detection of colorectal #cancer in inflammatory bowel disease #IBD: jobs.icr.ac.uk/vacancies/14... It's bench-to-bedside research, translating biology of pre-cancer evolution. Funded by @bowelcanceruk.bsky.social

Always a fantastic meeting! Register now.

We’re hiring! @jcellsci.bsky.social is looking for a Reviews Editor to join the team. This is a fantastic opportunity for someone who loves #cellbiology and wants to stay connected with the field. A great chance to work for an organisation that believes in helping the community! Details below👇

A back-to-work cartoon for @newscientist.com

🔥🎉 🧠 SuperThrilled to share our paper (preprint) - Human erythropoietin (rhEPO) reshapes the adult hippocampal chromatin landscape, around transposons to promote neurogenesis. 🧵1/8 Massive kudos to #UmutCakir who drove multi-omics through dark roads of the genome. www.biorxiv.org/content/10.1...

Happy New Year! We are looking for a postdoc with computational expertise to join our group. Deadline for application is 13th January. www.cam.ac.uk/jobs/researc... #newjob #postdoc #vascularbiology #atherosclerosis #cellplasticitycontrol #functionalgenomics #cellheterogeneity

Apply for Development's Pathway to Independence programme The programme aims to support a small number of researchers in the fields of developmental biology, stem cells and regeneration as they transition from postdoc to group leader. Read more ⬇️ thenode.biologists.com/apply-for-de...

Please consider applying, @dev-journal.bsky.social provides: - Profile raising - Mentor sessions - Leadership training and a growing network of supportive peers.

More marsupial fun from @lab-turner.bsky.social. Congrats @sermenchero.bsky.social

Another envelope protein in the human genome. Expressed in the placenta, of course.

Molecular effects of transposable element sequences in mammalian cells #TESky (Wen, MC.C., Welch, J.D. Genome Biol 26, 403 (2025)). Interesting review of new-found functions of TEs in mammalian genomes, especially over the last three years. doi.org/10.1186/s130... #TEWorldwide

Despite having been scooped big time by this paper from William Pastor's lab, really quite enjoyed reading it. Congrats to the authors.

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Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9

We wrote the Strain on scientific publishing to highlight the problems of time & trust. With a fantastic group of co-authors, we present The Drain of Scientific Publishing: a 🧵 1/n Drain: arxiv.org/abs/2511.04820 Strain: direct.mit.edu/qss/article/... Oligopoly: direct.mit.edu/qss/article/...

ooof this feels like most every university rn

📣 Meet the new ERC Synergy Grant awardees! Sixty-six research teams have been selected for funding, bringing together 239 scientists. Congratulations to all! ➡️ buff.ly/PSn3bi9 #EUfunded #HorizonEurope #ERCSyG

How do pluripotent stem cells resist harmful interferon responses to safeguard development? Through total epigenetic lockdown of ligands, sensors and effectors of IFN-I. In our preprint, James Holt shares his PhD discoveries on the ground state of immune evasion 😊: www.biorxiv.org/cgi/content/...

Spread the word! There is a professor position opening at our University @upcite.bsky.social. There are several possible (great) labs to join, but if you are interested in DNA methylation and epigenetics in mammals, don't hesitate to contact me directly!

📣 New preprint from the Jakobsson lab! We describe a detailed protocol to inhibit the expression of transposable elements in human pluripotent stem cells, developed thanks to @asapresearch.parkinsonsroadmap.org funding. Special shoutout to @anitaada.bsky.social! www.biorxiv.org/content/10.1...

For those interested in GRN evolution, please join us!

🚨Hiring a 2yr postdoc in the lab work on muscle biology, genomics & ALS. Expertise in the above advantageous, but work ethic, desire to learn/develop and being a good scientist/person more important Good collab with @droch.bsky.social so travel to CPH involved as well www.kcl.ac.uk/jobs/126245-...

Looking to pursue cutting-edge research in early development, maternal-fetal interaction, or placental biology? See 👇 - Funded PhD www.trophoblast.cam.ac.uk/phd-students... - Next Generation Fellowship www.trophoblast.cam.ac.uk/next-generat... - MPhil www.mphil.bio.cam.ac.uk/mphil-pathwa...

Come join us in Geneva for everything epigenetics and gene regulation. It will be a great meeting! Please repost! www.keystonesymposia.org/conferences/...

We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3

A TE insertion controls throat colour in wheatears. The gene involved (ASIP) is the same one that is epigenetically affected by an IAP insertion the famous Avy mice. As if we needed more reasons to love TEs.

An SVA insertion explains 0.5% cases of Lynch syndrome, apparently.

Fully-funded 4-year PhD studentships for home or overseas students, applications open till 4 November. 🔗 Please like and share to spread the word! www.trophoblast.cam.ac.uk/phd-students... Take a look at projects for 2025/26 www.trophoblast.cam.ac.uk/opportunitie... #PhD, #PhDPosition

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️ www.crick.ac.uk/careers-stud...

Check out these amazing opportunities from the Loke CTR in Cambridge (UK). I greatly benefited from a Next Generation Fellowship as a crucial stepping stone to independence.