In our last preprint we identify endogenous dsRNAs capable of activating the interferon response. Could these be relevant to our understanding of DiGeorge syndrome (22qDS)? In collaboration with @herassr.bsky.social and @heick.bsky.social labs www.biorxiv.org/content/10.1...

Happy to have played a small part in this new preprint on DGCR8, retrotransposons, and IFN regulation. Nice collaboration with @saramaciasrna.bsky.social @herassr.bsky.social www.biorxiv.org/content/10.1...

As tighter immigration policies are announced today, scientists continue to stress the importance of attracting international talent. Our director Paul Nurse spoke to the Observer about how this affects science in the UK: observer.co.uk/news/politic...

Our latest paper is out in NAR! 🥳 In collaboration with @saramaciasrna.bsky.social, we show DGCR8 haploinsufficiency disrupts pluripotency in hESC by affecting primate-specific miRNAs and TEs. Our findings highlight a co-evolved miRNA-TE network in primates. Read: academic.oup.com/nar/article-...

Our last paper in collaboration with Sara RHeras is finally out 🥳we modelled Dgcr8 haploinsufficiency in hESCs and exciting differences between 🧘🏽‍♂️and 🐭 at the transposon and miRNA content -HERVH & C19MC Thanks to all the coauthors and funders academic.oup.com/nar/article/...

I'm so excited about @saramaciasrna.bsky.social invitation to visit the Institute of Immunology and Infection Research, @edinburgh-uni.bsky.social on the 5th of February. I will be sharing our latest research on #RNAmodifications in #cancer

RECRUITING-PhD student to study the role of RNA-binding proteins in antiviral defence during early development. #crispr #iclip #omics Interested candidates, please email a full CV and a statement of interest. Open to both UK and overseas www.findaphd.com/phds/project...

Important reading - unfortunately not open access

And since we're here... 🥼 Join us as a Group Leader in #ComputationalBiology or #RNA Biology 🧬 More details via www.imb.de/jobs Application deadline is 5 January 2025 #sciencejobs #resilience #biostatistics

Had an amazing time visiting King’s college dept of Infectious diseases. Thanks @Rocio Nunez and @Hannah Mischo for the hosting and great tapas with @charlotte odendall …and a beautiful early morning walk by the river!

Happy to share our first #bluetorial & our latest #preprint, lead by postdoc @paulchammas.bsky.social. We used CRISPRa to disentangle the close relationship between Dux and MERVL elements in the induction of the 2-cell like state: #TEsky #MERVL www.biorxiv.org/content/10.1... (1/8)

#Immunosky #neuroskyence our team is expanding and we’re recruiting a colleague with a strong background in neuroscience (PhD level) to conduct curiosity-driven research into the role of adaptive immunity in controlling sleep. Details & how to apply here: www.jobs.manchester.ac.uk/Job/JobDetai...

This is so good! Thanks @tillysscott.bsky.social

Great discussion at the Genetics Society conference 🧬

Interested in tissue immunity in infection, focusing on adipose tissue, brain and immunometabolism? Then come join me & @juanquintana.bsky.social at @lydiabeckeriii.bsky.social as a research assistant Email to arrange an informal chat 🧪 #ImmunoSky #LGBTQSTEM www.jobs.manchester.ac.uk/Job/JobDetai...

On our way to the Genetics Society meeting at Leicester. We cannot wait to hear all about transposable elements 🧬 with my friend and collaborator Sara R Heras (soon joining this network too 😂)

New EdiRNA events for the new year! Funded by the @RNASociety. Great opportunity to network with other RNA biologists 🧬 (dsRNA included) from Edinburgh and beyond 🚀 Jan 29, 2025 Apr 9, 2025 Jun 11, 2025 Oct TBD, 2025 www.edirna.com/meetings

recruiting a PhD student interested in the role of RNA binding proteins 🧬for antiviral defence 🦠during embryonic development🐁 👶. Funding routes for both UK and international students are available 🌻. Please send your CV and motivation letter if interested saramaciasribela.wixsite.com/maciaslab