Please spread the word: We invite applications to a two-week Computational Biology workshop in Singapore, June 14-27. This NSF-funded workshop brings together 16-20 US grad students with international peers. Apply by March 21: compbioasia.net 🧵 Details below:

WOW! Very promising new tool to facilitate collaborative manual curation of TEs link.springer.com/article/10.1...

Yummy! www.cell.com/current-biol...

Rapid emergence of non-autonomous elements may stop P-element invasions in the absence of a piRNA-based host defence journals.plos.org/plosgenetics...

A Concise Guide for the Characterization and Curation of Transposable Elements in Insect Genomes -- by the excellent @valentinapeona.bsky.social link.springer.com/protocol/10....

Adaptive P-element insertions in a long non-coding RNA are associated with unique silencing properties www.biorxiv.org/content/10.1...

How the complex issue of delineating #Transposons families plays out in the interpretation of epigenetic experiments. Congrats Xun Chen and @guilbourque.bsky.social for leading this work, and thank you for having me on this! www.science.org/doi/10.1126/... #TEsky

Challenging the TE burst hypothesis in the adaptive radiation of Galápagos Asteraceae trees (Scalesia) with @naturalselection.bsky.social and team! mobilednajournal.biomedcentral.com/articles/10....

Waho this is impressive: github.com/zeqianli/tgv

New genomic & genetic insights into Mendel’s pea genes, including previously uncharacterised alleles 159 years after Mendel published his work, this is a real delight (especially for a geneticist) 🧪 @nature.com www.nature.com/articles/s41...

Manual validation finds only ultra-long long-read sequencing enables faithful, population-level structural variant calling in Drosophila melanogaster euchromatin www.biorxiv.org/content/10.1...

🧬🖥️ Thanks to Evangelos Karatzas at @ebi.embl.org, our _nail_ software for fast and sensitive protein sequence search is now available as an @nf-co.re module (nf-co.re/modules/nail...) (crates.io/crates/nail, github.com/TravisWheele...) Thanks Evangelos!

The writing’s been on the wall for a while, and in case anyone was unaware: YOUR GENOMIC DATA IS THE MOST VALUABLE ASSET THEY HAVE LEFT. Delete your data. Make sure you opt-out of any opt-outable options. Tell your friends and family - you know that technophobe cousin missed the memo. 🧪

Polymorphic transposable elements contribute to variation in recombination landscapes (drosohila 🪰) www.pnas.org/doi/full/10.... #TEsky

Rapid emergence of hyperparasitic elements may stop P-element invasions in the absence of a piRNA-based host defence www.biorxiv.org/content/10.1...

#Transposons are just the best!

Here, we demonstrate that Starships, a newly discovered group of cargo-mobilizing transposable elements, are active vectors of horizontally transferred DNA among eukaryotic species.

DFAM (database of transposable elements) 3.9 is out! A lot of cool new stuff and a special update for Drosophila melanogaster... 1/2 #Transposon #DFAM

Cool stuff from the Trono lab, as usual! Zinc-finger proteins with a co-opted capsid domain anchor nucleosomes over transposon sequences www.biorxiv.org/content/10.1...

LOCATE: using Long-read to Characterize All Transposable Elements doi.org/10.1101/2025... Mapping-based Genome Size Estimation doi.org/10.1101/607390 #Genomics #Bioinformatics #OpenScience

Do you want to annotate your #pangenome graph and its embedded genome ? Then GrAnnoT is for you ! 🖥️🧬 🧪 In the present paper, our PhD student Nina Marthe developed a Python tool, a user friendly one, that allows to 1/5 www.biorxiv.org/content/10.1...

RNA m6A and DNA methylation regulates transposable element chromatin activation and cell fate www.nature.com/articles/s41...

Very promising approach to characterize the mobilome in pangenomes from ! I wonder how this compares/complements to Pantera (@piosierra.bsky.social) and GraffiTE www.biorxiv.org/content/10.1... #TESky #SV #Pangenomes

www.biorxiv.org/content/10.1... #TEsky

Highly recommend!

Very excited to share our paper on Gene and Transposable Element expression in mammalian preimplantation development, online today! www.cell.com/cell/fulltex... A short thread to highlight some of our findings 🧵

www.cell.com/cell/fulltex... #transposons #mammals #development #transcripts

The great @johannconfais.bsky.social on a reference-free approach (panREPET) to annotate #Transposons in #pangenomes 🧬

After @tehub.bsky.social satellite workshop at #ICTE2024 and the creation of a working group on benchmark, what about the next step ? A manual curation workshop ? Share your thougth with the TEhub

@johannconfais.bsky.social and @clementgoubert.bsky.social are presenting @tehub.bsky.social at #PAG2025, an amazing resource and driven community for anyone interested in transposable element

Amazing talk of @nico971.bsky.social from @urgi-inrae.bsky.social on RepetDB #PAG32 urgi.versailles.inra.fr/repetdb/begi...

#PAG32 I'd bet that every genome studied at PAG has a least 1 #Transposon, if not thousands! Find us on Sunday for an exciting session on #mobileDNA!

#PAG32 About to discuss #Transposons in the grain weevil genomes using pangenomic tools! Weevilomics workshop, Pacific room F!

I have received a Wellcome Discovery Award to study the initiation of eukaryotic DNA replication, with 8 years of funding at the Francis Crick Institute. Looking for a postdoc in molecular mechanisms, cryo-EM, cryo-FIB and in situ structure? Contact me now! 3 postdoc positions advertised soon.

I would really appreciate a wide sharing of this post, as the candidate profile I am looking for is outside of my regular circle. Thank you so much. More info and how to apply here: uu.varbi.com/se/what:job/... (2/2)

It was only a matter of time. www.cell.com/cell/fulltex...

Let me know If Google does that!

Apple & AI There I was hoping Apple would make this opt-in… 😑

Posting this to remember the day I have more followers than @cedricfeschotte.bsky.social 🤣🤣🤣

We've got to do better. This field of 'social epigenomics' looks to be very lacking in self-criticism and necessary rigour, it is no wonder that these studies are wide open to criticism.

We found this ghost redwood tree this weekend while camping this weekend @jrossibarra.bsky.social . It's a rare chlorophyll mutant growing clonally off of the base of huge coastal redwood

🎉 Our #GraffiTE paper is out!!! t.co/TmoSL3WQ1P If you are interested in #Transposon insertion polymorphism, this is for you!

Tracking transposable element (TE) activity in genomics data can be a pain, but there are solutions! Our lab built TEtranscripts -- which we've updated to work for small RNAs (TEsmall), bulk RNA at the locus level (TElocal), and in single-cell data (TEsingle). Check it out! www.mghlab.org/software

Please register for the course on Transposable elements in #genomics and #datascience. We will be sharing the magic of #nanopore long reads for #transposon expression #tesky

I use this example in all my intros to TEs!

If you like #Transposons 👾 check out this feed and tag your posts with #TEsky! Thanks @tobybarilbio.bsky.social 🤗 bsky.app/profile/did:...

Come to Tucson!

Evolutionary biologists teaching intro courses: "Hardy-Weinberg is the null model of evolution." Evolutionary biologists studying bacteria/archaea/asexual eukaryotes: #evolution