#TESKY 🎉 Phenomenal work! After the humans, the variety of mouse immune cell systems also co-opts transposon-derived enhancers/promoters. Big Kudos to Jason, Andrew Grimson, and @cedricfeschotte.bsky.social

Does a neuron’s "address" define its function? 🧠 Featured in @lefigaro.fr, new nature neuroscience research from Denis Jabaudon & colleagues shows that misplaced neurons can work perfectly & process senses. Brain structure ≠ function! For more information: www.linkedin.com/posts/instit...

🔥🎉 🧠 SuperThrilled to share our paper (preprint) - Human erythropoietin (rhEPO) reshapes the adult hippocampal chromatin landscape, around transposons to promote neurogenesis. 🧵1/8 Massive kudos to #UmutCakir who drove multi-omics through dark roads of the genome. www.biorxiv.org/content/10.1...

Happy new year and 3 more days to apply for Computational biology post doc position in my lab #Paris #transpoosns @inem-necker.bsky.social @institutimagine.bsky.social

This is the view where we shall have our regular lab meetings. Maybe this persuades you to join our team. #hiring #postdoc #computationalBiology #multiomics #deeplearning

#hiring #postdoc #bioinformatics We’re opening a Computational/Bioinformatics postdoc position in my new lab at INEM in Paris, connected with Imagine and Institut Pasteur. The big theme: 👉 How do endogenous retroviruses and other mobile DNA rewire human immune regulation and genome control? 👇⬇️🧵

Congrats Manvendra, well deserved!

Great news for the scientific community in France (especially TE aficionados :))!!

It’s debatable, there exists arguments from both sides. I bet the quality of science will be diminished. When experts review the paper or grants, they get an idea of which citations hold how much water. AI doesn’t unless we first train it. So, I think it’s too soon to implement for grant review

#NewPI #Neuroscience #Immunology #Transposons #SciComm #HERVs Stay tuned, a few postdoctoral, both molecular and computational biology positions are gonna be advertised soon.

Benchmarking cell type and gene set annotation by large language models with AnnDictionary www.nature.com/articles/s41... 🧬🖥️🧪 github.com/ggit12/anndi...

🎉 Thrilled to Announce a New Chapter! 🧵 I’m honoured to share that I’ve been appointed as CNRS Chaire de Professeur Junior (CPJ) at Université Paris Cité from 1st Jan. My independent lab is hosted at the Necker Institute (INEM), with co-affiliations at the Imagine Institute and Pasteur Institute. ⬇️

"Jane Goodall showed us what a life in science could look like: rigorous discovery paired with fierce advocacy for what you study. She gave the world six decades of groundbreaking research on chimpanzees and their habitats, then turned that knowledge into a global movement for conservation." (1/2)

Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life. www.nature.com/articles/s41...

Paper accepted!!!! Congratultions to @lizebonaaugust.bsky.social Blanca del Rosal and Leslie Yeo it was a pleasure to work together on this amazing project! 🎊🎊🎊🎊

One of my all-time faves

📣 Our department is hiring an Assistant Professor in Evolutionary Cell and Molecular Biology to join the @weillinstitute.bsky.social PLS spread the word! academicjobsonline.org/ajo/jobs/30607

I'd be leaving soon for the new challenges Before I go, here are a few brain’s stories on the table: 1 out in Nat Comm, 1 in press at Mol Psy, and 🤞 for the third. Preprints here: www.biorxiv.org/content/10.1...; www.biorxiv.org/content/10.1...; www.biorxiv.org/content/10.1...; Onwards. 🖤

www.cell.com/cell/abstrac... A host organelle (in sea slugs) integrates stolen chloroplasts for animal photosynthesis

A study published in Genome Biology explores the role of transposable elements in antiviral resistance to HIV. The findings open new avenues for understanding the molecular mechanisms of viral control and developing targeted interventions for HIV-1 treatment. #Epigenetics

New ERC Starting Grant for Juliane Glaser to study role of epigenetic mechanisms, specifically the control of transposable elements, in mammalian embryonic development. Read all details here: www.ie-freiburg.mpg.de/6057908/2025... Congratulations @julianeg.bsky.social @erc.europa.eu #ERCStG

17 ERC Starting Grants for Max Planck scientists! This puts the Max Planck Society at the top of the European ranking. mpg.de/25324951/erc... Congratulations to all grantees 🎉👏 #ERCStG @erc.europa.eu

Not sure if they tested cooperative bindings of TFs, which might have been the key player for determining their activator/repressive roles. Also, it might not be feasible to test in Yeast system for all TFs. Great study, anyways.

Defending US democracy: the role of scientists @science.org www.science.org/doi/10.1126/...

lh3/longdust: Identify long STRs, VNTRs, satellite DNA and other low-complexity regions in a genome github.com/lh3/longdust 🧬🖥️🧪

New in @natbiotech.nature.com: a team led by scientists at MSK and ‪University of Toronto have developed a new platform to facilitate the study of RNA-biding proteins (RBPs) across hundreds of species of plants, insects, and animals.

🧵1/ Introducing Stellarscope: an EM-based tool for quantifying locus-specific transposable element expression in single cells. A single-cell transposable element atlas of human cell identity: Cell Reports Methods www.cell.com/cell-reports... @hamarillo.bsky.social #TEHub #singlecell #genomics

Exactly two weeks left to submit your abstract to the EMBO Mobile Genome Workshop. ☝️this year we will select from abstracts 2 “long” talks to highlight last minute breakthrough from early career scientists. Apply! July 29th

Just dropped our Mobile DNA review on HERVH, an ancient retrovirus now repurposed to build and defend the early human embryo. Call it genomic up-cycling! I felt HERVH went unnoticed this year, so we published this as a refresher; two fresh data papers - coming soon. 🔗 doi.org/10.1186/s131... 🧵1/3

Woohoo! From superstars ionut and Marta in the Frisén lab! www.science.org/doi/10.1126/... can’t wait to see what the anti-neurogenesis folks say about it 😃

😲

Complete ape genomes! 🦍🦧 Our closest relatives get the deluxe sequencing treatment, resolving the most complex & often most interesting parts of the genome. Happy to make a tiny contribution alongside @panpan100.bsky.social to awesome teamwork & fantastic resource. www.nature.com/articles/s41...

💥🥳 At long last, our latest paper is out! Gag proteins of endogenous retroviruses are required for zebrafish development www.pnas.org/doi/10.1073/... Led heroically by Sylvia Chang & @jonowells.bsky.social A study which has changed the way I think of #transposons! No less! 🧵 1/n

Lovely! The addiction model 😍 So glad to see it out. Big Congrats to Sylvia and @jonowells.bsky.social

Two rejuvenating days of exciting science, fun times, and beautiful sights in Tuebingen 🇩🇪 THANKS to Vikas Bansal & Daniel Sauter @unituebingen.bsky.social and Susana Coelho @maxplanckcampus.bsky.social for hosting & @manusingh.bsky.social for joining 🙏😊

I am Absolutely delighted to share the preprint of our last collaborative efforts where we investigated the impact of sonostimulation of Mesenchymal Stem Cells. Thread -1- www.biorxiv.org/content/10.1...

🤯 cryo-ET of copia viral-like particles lurking at the nuclear pore of intact Drosophila eggs! Amazing work by @svenklumpe.bsky.social & more cool findings in this collaborative paper illuminating the replication cycle of an iconic retrotransposon! www.cell.com/cell/fulltex...

The below average intelligence - trump confidently blabbed in public about fundings to research on transgender mice when they are just transgenic mice . I weep for future

I turned off the news and put a serial killer documentary for relaxing

Today is a devastating reminder that infectious diseases don’t care what your ‘beliefs’ are. Everyone is likely to be affected directly or indirectly. Serious challenges require serious people at the helm. Protect your loved ones. Educate. Advocate. The cost of not doing so will be too much to bear.

This humour is way too dark for me. I am even scared to put any caption on it!

Great thread of our most recent paper about how Transposons may make some people HIV-resistant, none other than by our @cedricfeschotte.bsky.social Plenty of good reads here ⬇️

Feels awkward but necessary to celebrate scientific progress in this imperiled time for US biomedical research. Proud of our latest paper out today exploring the role of transposable elements in antiviral resistance to HIV 🦠 genomebiology.biomedcentral.com/articles/10.... 🧵1/n

Awesome teamwork co-led brilliantly by @manusingh.bsky.social & Sabrina Leddy; in collaboration with Doug Nixon’s lab - and of course funded by NIH. Thank you all! 🙏🙏🙏

Paper out !!🥳big thanks to all authors @marliesoomen.bsky.social @diego-rt.bsky.social @kaessmannlab.bsky.social @jonathangoeke.bsky.social @lorenzamottes.bsky.social & 'bluesky-less' Lots of interesting new TE (& genes) biology Data fully browsable💻 👉 embryo.helmholtz-munich.de/shiny_embryo/

Diversity at its best - They have brought a cuisine called "Mexican Doner" in Hamburg Germany. Its middle-eastern proteins with Asian sauce, in an American bagel sprinkled with veggies, beans, corn and jalapenos. Gosh, that's the best döner I had. One more reason to not vote for AFD ;)

“ERC succeeds because it’s different. Its simple, tailored procedures allow Europe’s best researchers to thrive. Bureaucratic processes designed for other programmes should not be imposed on it.” @marialep.bsky.social spoke up for an independent ERC with a doubled budget today @europarl.europa.eu

It was amazing to have interacted with Jeff Boeke, from NYU and also witnessed his phenomenal talk at @mdc-bimsb.bsky.social He has now put all human chromosomes in yeast, One by one. Also, they made parrots have conversation in five languages English, French, German, Swedish and Spanish 😂

REFUSE💪RESIST If you’re looking for a template to contact your congressperson and urge them to intervene about the devastating NIH indirect cost cap policy, here is a good one I just use. It’s time to make ourselves heard! www.votervoice.net/mobile/NAEVR...

“We must accept finite disappointment but never lose infinite hope.”– Martin Luther King Jr. “Remember that all through history, there have been tyrants and murderers, and for a time, they seem invincible. But in the end, they always fall. Always.”- Mahatma Gandhi