Genes are not On/Off switches. In a new preprint we show that HDAC3 is key to establish correct transcriptional dose in development. Gr8 work from N. Stamidis @ucph.bsky.social and collab. @jamiehackett.bsky.social @gregersenlab.bsky.social . Huge thx to all authors! www.biorxiv.org/content/10.1...

Very excited to share an excellent review from @teresa-urli.bsky.social, published one week before her PhD defense! We did a deep dive into the fascinating biology of the variant Polycomb complex, PRC1.6 (1/5) journals.plos.org/plosgenetics...

🚀 Looking for a Bioinformatician / Data Scientist to join our crew and explore regeneration through single-cell genomics & evolutionary biology! @mpi-bio-fml.bsky.social 📩 Questions? Contact us ✉️ 🔗 Apply here: www.mpg.de/25243280/bio...

Check out @annaamonaco.bsky.social piece on our recent story 🧬🦠 ✋🏻 & have a look at her website, Anna is an amazing science communicator and writes about discoveries on the non-coding “dark” genome! Thank you for highlighting our work 🤩

🥳 Thrilled to share that our lab has been awarded an ERC StGrant for our project SigReg: Signal to Regeneration! How can we unlock limb regeneration in adult mammals? It’s time to apply what we learned from 🐸 ➡️ 🐭 Thank you @erc.europa.eu for supporting ambitious science!!!

I am also very happy to share this good news my colleague @flurylab.bsky.social @mpi-ie.bsky.social 🥂🥂

🥳 Very grateful for the support of the ERC Starting Grant for my newly established lab! We will study how transposable elements contribute to mammalian embryonic development. We will have positions available next year. Stay tuned!

Our new review is out in Trends in Cancer. We had fund writing this :) We discuss the roles of retrotransposons in immune modulation in normal and malignant hematopoiesis. www.cell.com/trends/cance...

We take for granted that our hands have two sides and can articulate in an endless number of ways. But what about a fish’s fin? Can a fish know something “like the back of its fin,” or have its future told with a fin palm reading? Check out this bluetorial to find out 👇🧪🧬🐟 doi.org/10.1101/2025...

🚨 Job Alert: we seek a Lab Manager for @juliabatki.bsky.social's new group (start Mar 2026), which will study cell fate regulation during organ development. Join the Batki's group to drive experiments & lab operations! Apply at: www.fmi.ch/education-ca...

Three-Year Funded Postdoctoral Position to study organelle architecture in mammalian oocytes – Terret-Verlhac Lab, CIRB, Collège de France (Starting 2026). For more information, please contact: [email protected]

The peppered moth is a textbook example of natural selection, its colours shifting with the soot-darkened trees of the Industrial Revolution. But the genetic secret behind its “dark” form took 150 years to uncover: a new “jumping gene” that rapidly took over the population. 🦋 tinyurl.com/4zrc4e93

I am excited to share that I will join the Friedrich Miescher Institute @fmiscience.bsky.social in Basel as a group leader, starting my lab in March 2026 🎉 We will explore cell fate regulation during organogenesis, with a focus on how cell elimination underlies the emergence of functional tissues.

🧬 New study from the Kinkley Lab! 🧬 In collaboration with the Vingron and Hnisz labs at the MPIMG the team has gained new insights how the epigenetic reader PHF13 regulates it´s affinity to bind to chromatin. Read more: www.molgen.mpg.de/2025-07-28-o... Congrats to first author Francesca Rossi!

To all post-docs: The Genome Biology dept ‪@embl.org has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Grateful and excited to launch the Otsuki Regeneration Group at the Hubrecht Institute! 🔗 www.hubrecht.eu/research-gro... We study how tissues regenerate - and use those principles to build 3D tissues in vitro. Full announcement: www.linkedin.com/in/leo-otsuk... @hubrechtinstitute.bsky.social

Our new story in Nature Genetics: endogenous retroviruses can produce viral-like particles in the embryo resulting in apoptosis and congenital malformation. If this would happen in human, it wouldn't leave a trace. No WGS or other analysis would identify this. www.nature.com/articles/s41...

😍😍😍 Thank you Anna!

So happy to see the illustration of our work featured on the cover of @natgenet.nature.com 😍 It represents digits desintegrating into viral like particles. Thank you so much @annaamonaco.bsky.social for making this design!

It's that time of the year - @mdc-berlin.bsky.social Pride Symposium in its 4th edition with great talks and discussions on intersectionality and DEI in general. As Neil Young said on Waldbuehne the other day - "Times are rough, we gotta look out for each other" 🫶 #MdcDiversity

Thrilled to see our revised preprint now published in Nature Ecology & Evolution! If you’re curious about how to build a bat wing by re-using existing gene programs, check out the link or the tutorial below. Big congratulations to all co-authors!! Thanks to reviewers! www.nature.com/articles/s41...

Very happy to share our protocols paper for CELLO-seq. This will make single cell long read RNA-seq more accessible and provides analysis guidelines. We hope this helps the #transposon #TEsky community and folks working on #singleCell isoform and allelic #gene expression. doi.org/10.1038/s415...

Our study on a male-essential microRNA and the evolution of other dosage compensation mechanisms in birds is now out in Nature! www.nature.com/articles/s41...

How did the bat get its wings? New research from a collaboration between the labs of Stefan Mundlos (MPIMG), Dario G. Lupiáñez, and Francisca M. Real (@cabd-upo-csic.bsky.social) show how genetic programs were reused during the evolution of mammalian flight. --> www.molgen.mpg.de/news-2025-fl...

Exactly two weeks left to submit your abstract to the EMBO Mobile Genome Workshop. ☝️this year we will select from abstracts 2 “long” talks to highlight last minute breakthrough from early career scientists. Apply! July 29th

🏳️‍🌈Our editor @slefkopoulos.bsky.social discussed with @jzylicz.bsky.social about the importance of celebrating Pride, representation in science, and more! Happy Pride! Read here: rdcu.be/ewfba bit.ly/3Uc72TO

Interested in developmental epigenetics? So are we! Apply now to join us for your postdoc! Multiple positions across multiple groups @mrc-lms.bsky.social Projects spanning germline demethylation, gene regulation, genome architecture in development & disease 👇👇 lms.mrc.ac.uk/work/vacanci...

We wrote a review on Transposable Elements (TEs) and almost all aspects of TE silencing and their roles in biological processes & disease. www.nature.com/articles/s41...

🎉ONLINE @natgenet.nature.com 📰Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes. By @julianeg.bsky.social, Giulia Cova, Stefan Mundlos and colleagues. ⬇️ www.nature.com/articles/s41...

Our work bridging enhancer-promoter proximity to phenotypic outcomes in vivo is out! Shout out to @olimpiabompadre.bsky.social, to Marie Kmita's lab, and to all the co-authors. www.nature.com/articles/s41...

Also, check out the News & Views summarizing our findings, written by Youjia Guo & @themodzlab.bsky.social 🤩🤩 www.nature.com/articles/s41...

Finally out! 🥳 Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com 🧬🦠🐁 Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5

Our paper describing the Range Extender element which is required and sufficient for long-range enhancer activation at the Shh locus is now available at @nature.com. Congrats to @gracebower.bsky.social who led the study. Below is a brief summary of the main findings www.nature.com/articles/s41... 1/

Paper alert! I am really pleased to share the final version of the work led by Irène Amblard in the team on a regulatory switch controlling Cdx2 expression during posterior body development! #regulatorylogic #devbio @mrc-lms.bsky.social @imperialmed.bsky.social

Very excited to have joined the @mpi-ie.bsky.social ! Thank you for the warm welcome 🤩🤩

🚨 Check out the latest from @trono-lab.bsky.social showing how evolutionarily young transcription factors contribute to human cell cycle regulation! Brilliant work led by Romain Forey and Cyril Pulver, now published in Cell Genomics. Check it out ! www.cell.com/cell-genomic...

⚠️ I am really excited to share the work of Anastasios Balaskas, an excellent PhD candidate in the lab, with the wider world. Tasos made a significant advance: generating a stem cell-based embryo model that contains both posterior and anterior neural tissues of the late-stage gastrulating embryo.

Mustering the courage to share my latest scicomm endeavour: I channelled my love for writing into a blog where I can hopefully bring the marvels of evolutionary biology and non-coding DNA to all Science lovers! darkgenomevo.wordpress.com/2025/06/22/i...

Postdoc🚨! Come join our HFSP team to uncover how chromatin moves in cells and what this means for genome function! Great opportunity to combine single-cell genomics, live imaging and polymer physics in the unique mammalian retina with @andersshansen.bsky.social, Davide Michieletto & Sandra Tenreiro

Textbooks: “Enhancers are just a bunch of TFBSs” But how do they REALLY work? New paper with many contributors here @berkeleylab.lbl.gov, @anshulkundaje.bsky.social, @anusri.bsky.social A 🧵 (1/n) Free access link: rdcu.be/erD22

Happy that our preprint from early this year, uncovering the regulation a somatically "hot" endogenous retroelement locus, has now found its home in @narjournal.bsky.social. "TEsky" doi.org/10.1093/nar/...

Transitions in development – an interview with Jan Żylicz We met with @jzylicz.bsky.social‬ (reNEW @ucph.bsky.social) on Teams to learn more about working abroad, finding a good mentor and his career path so far: journals.biologists.com/dev/article/...

Save the date 📅! Our TriNational #devbio #stemcell Meeting 2025 will be held in Freiburg on Sept. 19th. As always, participation is free and talks will be selected from early career scientists. Joun us 😊 Info: devstemcell.org/home @biozentrum.unibas.ch @uni-freiburg.de @igbmc.bsky.social

Students (Master's/PhD), do not miss this fantastic Developmental Biology course of @sorbonne-universite.fr and @institutcurie.bsky.social - It is FREE and open to international students, however, room and board + travel are not included. training.institut-curie.org/courses/deve...

If you are interested by epigenetics, early human development in excellent scientific environment in middle of Paris, we are recruiting a postdoc. app.beetween.com/WeaselWeb/p/... Don't hesitate to apply or share the post !

This is great news for Freiburg and the #Epigenetics community in the region! Congratulations to @simonelsasser.bsky.social – and we say welcome back to Freiburg. 😀

Delighted & excited to share our latest preprint on non-canonical enhancers in human pluripotent stem cells, the result of a fantastic and fun collaboration with @guenesdoganlab.bsky.social‬: www.biorxiv.org/content/10.1... 🧵 below

Did you know we have a dedicated Jobs Board? Whether you're looking for your next job, or you have an open position to advertise, do check out our Jobs Board: thenode.biologists.com/jobs/ #DevBio #StemCells

Check out the work of Mikie, Tobi, @danielibrahim.bsky.social & al. on enhancer conservation despite sequence-divergence in the developing ❤️ of 🐭 and 🐣 It was great to see this story unfold over the past years! Congrats to all authors!!!

Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury. www.nature.com/articles/s41... A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka. 🧵1/14