Hi #TEsky, please remember that we have an amazing community in the TransposonsWorldWide slack channel (join.slack.com/t/transposon...), which I encourage you to join. Another great resource is tehub.org. Please share !

We are looking for someone to lead the new Facility for Protein Biochemistry & Biophysics at the MPI of Immunobiology and Epigenetics in Freiburg — please spread the word and apply if you are interested!

Yesterday, half of #Freiburg’s business world gathered at the Europa-Stadion: 5k company run #b2run. We were there too – driven by curiosity – with runners from the @flurylab.bsky.social @julianeg.bsky.social @jumanaaha.bsky.social labs & other departments of the MPI-IE. Congrats to all finishers! 💪

My first PhD paper is out in Nucleic Acids Research! We describe "Ab-trapping" - an antibody artifact that distorts assays relying on antibody diffusion (microscopy, CUT&Tag, CUT&RUN). The revisions made the story much stronger. Check it out! doi.org/10.1093/nar/...

Applications are open for the international course “Developmental Biology” organized by the Institut Curie in partnership with @sorbonne-universite.fr 📅 Oct. 19–28, 2026 (Paris) ⏳ Jul. 19 & Sept. 18 🔗 training.institut-curie.org/courses/developmental-biology-2026

🚨Preprint Drop🚨 We are very pleased to release our study on DNA methylation dynamics at enhancers during ESC differentiation! This work was led by Marlet Morales-Franco and Priscillia Lhoumaud 🧵(1/13) www.biorxiv.org/content/10.6...

📣 POSTDOC position available in the Feschotte Lab at Cornell to work on #TRANSPOSONS! More details below. Pls send informal application or inquiry ASAP by DM or email to cf458_at_cornell.edu. Pls spread the word 🙏 #TEsky www.thefeschottelabatcornell.com

We are over the moon! 🎈 Dr. Marieke Oudelaar joins the MPI-IE as a new #MaxPlanck Director, heading the newly established Department of Genome Biology She studies how the 3D folding of DNA controls gene expression – more details below ⬇️ Welcome to #Freiburg, @mariekeoudelaar.bsky.social!

🚨Happy to share a new PreLight covering the latest #preprint by the Meissner lab (@molgen.mpg.de) on acute SUZ12 degradation during TLS formation. A work brilliantly executed by @dannimklee.bsky.social et al. Get to know more about him and his work here ⤵️ prelights.biologists.com/highlights/t...

New paper out in @cp-cellstemcell.bsky.social. We uncover unexpected complexity in how metabolism changes when the embryo implants or when stem cells exit naive pluripotency, revealing a central role for dynamic TCA cycle rewiring in cell fate decisions. www.cell.com/cell-stem-ce...

New Preprint alert!🚨 Super excited to share my postdoc work now on BioRxiv. How does PRC2 loss lead to developmental failures? We combined rapid protein degradation with TLS embryoid models to uncover temporal and lineage-specific dependencies 🧬. Preprint: doi.org/10.64898/2026.04.18.719361

plz repost 🙏 we are looking for a technician to start this summer/fall for 1-2 years to work with me at Cornell in the labs of @cedricfeschotte.bsky.social and Andy Clark, in collaboration with @corriemoreau.bsky.social on flies & termites 🪰🐜🧬🔬 Ithaca is gorges! jobs.hr.cornell.edu/us/en/job/WD...

A new study shows how different regulatory genetic elements control when a key developmental gene is active in the body. The findings could explain subtle differences seen in patients with congenital limb malformations, for which the underlying disease mechanisms often remain unknown.

In this interview, @juliabatki.bsky.social, FMI’s newest group leader, reflects on the early curiosity that drew her to science, why FMI is the right home for her lab, how studying cell clearance could help us understand disease, and her love of improv. www.fmi.ch/news-events/...

🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders? In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸 🔗 www.science.org/doi/10.1126/... #EvoDevo

The research highlight of our recent work on nuclear speckles is online. The photo choice is eggcellent. Happy Easter! 🌸🐰🥚 www.nature.com/articles/s41...

Yolanda and I enjoyed writing this review on X-chromosome reprogramming in the mammalian germline. 👇 Hope you'll enjoy reading it too! @biochemsoc.bsky.social #epigenetic #germline #XCI @igmm-montpel.bsky.social @biolum-montpellier.bsky.social @umontpellier.bsky.social

It is a beautiful day in the TriRhena region. ☀️ 😎 Perfect for traveling to today’s Gene Regulation at @igbmc.bsky.social in Strasbourg 🇫🇷. Check out the program with exciting talks in chromatin, transcription & ZGA including the NewPI talk by @simonelsasser.bsky.social.

Very excited to announce the FIRST symposium on epigenome editing! These tools are becoming widely used in mol bio, ag & therapy. It's time to bring leaders together to discuss this rapidly growing and exciting field. And why not in Paris! Please register & share! (1/2) ctrlepiedit.sciencesconf.org

I am very happy to share that I've started my new position @upcite.bsky.social and opened my lab @institutimagine.bsky.social 🎉 In the lab we will study how differences in X-linked gene dosage between the sexes affect fetal growth and survival and contribute to sex differences later in life 👩‍🔬🧪🧬🧫

Find our latest Perspective article in Nature Genetics on "The role of KRAB zinc-finger proteins in expanding the domestication potential of transposable elements" at www.nature.com/articles/s41..., with implications for the future of research on the cause of human disease.

We wrote a piece on how easy it is to write gene regulatory sequences. - Turns out, it isn't that easy even though we know a lot about cis-regulation. huge credit to @carldeboer.bsky.social to seeing this through so our thoughts aren't lost. I promise, it's a worthwhile read!

Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social doi.org/10.1016/j.ce... Read the thread👇 for the highlights of our findings.

🤩💪 Out now! 3D regulatory hubs in sex determination With @mamartirenom.bsky.social & Capel labs, led by @imotagom.bsky.social & @jrotwitguez.bsky.social 1️⃣ METALoci – explore #3DGenome 🧬 2️⃣ Non-coding region controlling Fgf9 🧩 3️⃣ Meis genes = new key players 🌟 👉 rdcu.be/e5sm2 1/n Bluetorial 👇

We're recruiting a PhD student to try and understand stress memory and gene function, using gene editing, in trees! #plantscience

To turn spatial data into a 3D object, check our protocol (open source, napari plug-in). @guignardlab.bsky.social @adrianobolondi.bsky.social @ibdm.bsky.social For example, if you have spatial RNA-seq as sections, you can align them automatically to analyse directly in 3D. bio-protocol.org/e5607

During germline epigenetic reprogramming, Polycomb must be restricted in the gametes to ensure proper genome regulation in the fertilized embryo. 2 must-read papers assess what happens when Ezhip (Polycomb antagonist) is lost. They come to highly similar conclusions and should be read in tandem 1/4

New preprint from the lab! We dig into the regulatory roles of TEs in the mouse placenta, with some surprising findings. Led by the awesome @smamante.bsky.social. Particular kudos to him for navigating the many twists and turns of the project.

It is finally out! If you are interested in TE-derived CREs, and newly described, but evolutionary old KZFP-TE mechanistic modalities, read it at www.cell.com/cell-reports.... Thankful to everyone who took part in this work, namely @orpsf.bsky.social and other @trono-lab.bsky.social members. 🫀🧬✨

⚠️ The final work of two former PhD students Till @tschwammle.bsky.social and Verena @verenamutzel.bsky.social is out! ➡️⬅️ They dissect how memory can arise from antisense transcription using mathematical modelling 💻, genomics 🧬 and synthetic biology ⚒️! link.springer.com/article/10.1...

Would anyone out there be able to share some Mus Spretus DNA with us? 🐀🧬 Any tissue of origin, for PCR amplification of selected genomic regions. Many thanks in advance!

🧬 We’re #Hiring a #Bioinformatician/ Computational Biologist! #Single-cell genomics, #Epigenomics & #3Dgenome biology in #Zebrafish #DevBio 🐟 📍 @cabd-upo-csic.bsky.social, CABD, Seville (Spain) 🕒 Full-time, 3-year position (start March 2026) 📅 Apply by Feb 15, 2026 👉 drive.google.com/file/d/1M8rp...

#APPLYNOW 📣 The CIBSS Team is hiring! We are looking for someone passionate about helping early-career researchers develop their skills, qualifications and career prospects🧑🏽🔬🧬 ➡️ Coordinator of Early-Career Programs and Diversity Management 🗓️Deadline: Jan 18, 2026 🔗 uni-freiburg.de/en/job/00004767/

Our work on #RegulatoryTrajectories is out today in Nat. Comms: www.nature.com/articles/s41... Led by @raquelrouco.bsky.social, this study establishes a new framework to study how enhancer landscapes act sequentially at developmental loci and are silenced to shape gene expression patterns. (1/n)

🚨Application for the MPI-IE international PhD program is ongoing🚨 If you are interested in #epigenetics #genomics #cellbiology #devbio & more, apply before February 6th! My lab will recruit a student to work on the contribution of #transposable elements in development and disease 🧬🦠

🧬 Join our Deep Sequencing Facility! 🧬 We are looking for a Scientist as Application Specialist »Next Generation Sequencing« (m/f/div) to work with cutting-edge tech like AVITI24 & NovaSeq. 📍 Freiburg, Germany 🇩🇪 📅 Apply by Feb 2, 2026 🔗 jobs.ie-freiburg.mpg.de/jobposting/d...

🎄🌟 Season’s greetings from the entire team of the Max Planck Institute of Immunobiology and Epigenetics in Freiburg … with a few impressions from our Winter Cookie Fair on December 11. ❄️ We wish you Happy Holidays and best wishes for 2026!

Activator-promoter compatibility in mammals - Hcfc1 is a key and intrinsically CGI-promoter-specific co-activator that cannot activate non-CGI promoters. Lead by @nemcko.bsky.social & Kevin Sabath in collab. with @plaschkalab.bsky.social @impvienna.bsky.social www.biorxiv.org/content/10.6... (1/2)

Our preprint "Predictive design of tissue-specific mammalian enhancers that function in vivo in the mouse embryo" is on bioRxiv: www.biorxiv.org/content/10.6... . Amazing collaboration by @shenzhichen1999.bsky.social, Vincent Loubiere (@impvienna.bsky.social,@viennabiocenter.bsky.social),... (1/2)

Do you want to play a key role in running a cutting-edge stem cell and embryology lab at reNEW @ucph.bsky.social ? We’re hiring a Lab Manager to support our team and help with stem cell and animal work. Apply before Feb. 1st : rb.gy/d5uf17

🚨We are recruiting two PhD students 🚨 1) Quantitative & dynamic analysis of limb-regenerative signaling centers w/ @osvaldo-chara.bsky.social 📶🧮💻 🔗https://www.phd.tuebingen.mpg.de/80704/Quantitative-and-dynamic-analysis-of-limb-regenerative-signaling-center-interactions

Very happy to share our paper rdcu.be/eUImj out today in @natcellbio.nature.com 🎉🎉🎉 We uncover an unexpected role for endogenous Xist RNA in regulating X-linked genes that escape X-inactivation.

Come do your PhD with @stemundi.bsky.social and me to uncover mechanisms of lncRNA function using cutting-edge techniques in vivo! 🧬 Project and application details below 👇

Join us for tomorrow´s 📢 CIBSS Seminar Series 🗓 09 Dec 2025 | 12:00–13:00 👩‍🔬 @julianeg.bsky.social, (@mpi-ie.bsky.social) 🎙 Endogenous retroviruses and mouse developmental malformations 📍 Lecture Hall, Institute of Biology I, Hauptstr. 1 See more: kurzlinks.de/iplv #CIBSS #Science #Immunobiology

🎉 Our deconstructed, stem-cell–based approach to studying signaling centers and limb-development cell types is out! 🥳 So nice to see it in its final form after the preprint— and huge thanks to the community for all the enthusiasm and interest since then! www.science.org/doi/10.1126/...

📣We are looking for a Project Assistant to join my group at the Wallenberg Center for Molecular Medicine at Umeå University. Join us if you are interested in transposable elements, epigenetics and human brain aging. 🧠🧬 Dont hesitate to reach out with any questions! 📣 umu.varbi.com/en/what:job/...

Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions: Mentoring Profile raising Leadership training Network building Spread the word... www.biologists.com/grants/devel...

Here is a copy of last year's Twitter thread explaining our preprint - jump to (21) for the new stuff 👀 Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function now revised and journal accepted at www.science.org/doi/10.1126/... 🧵👇

Join @mpercharde.bsky.social Lab at the MRC LMS! We have an 18mo postdoc position to cover a couple of projects (maternity leave and paper revisions). The projects are focussed on chromatin in early mouse embryos and metabolism in mouse embryonic stem cells and pluripotency.