Do transcriptional activators work on any promoter? Our data says no. 🙅‍♂️ Despite driving ~2/3 of mammalian genes, CpG island (CGI) promoters have remained a puzzle. We identified >50 activators that are exclusively compatible with this promoter class. 🧬

Systematic Discovery of Pathogen Effector Functions across Human Pathogens and Pathways https://www.biorxiv.org/content/10.1101/2025.11.17.687821v1

The Vienna BioCenter Summer School 2026 call is now open for talented undergrads, it's a great opportunity for students who are interested in graduate study in the life sciences. Please RT https://training.vbc.ac.at/summer-school/

Loving today's news that the mysterious "fedora man" outside the Louvre heist was actually a 15-year-old museum visitor who dresses like a 1940s French detective all the time, just because. apnews.com/article/louv...

Could one envision a synthetic receptor technology that is fully programmable, able to detect diverse extracellular antigens – both soluble and cell-attached – and convert that recognition into a wide range of intracellular responses, from gene expression and real-time fluorescence to modulation..