sRQA: AN INTEGRATIVE PIPELINE FOR SYMBOLIC RECURRENCE QUANTIFICATION ANALYSIS https://www.biorxiv.org/content/10.64898/2026.03.31.715624v1

A phosphorylation switch in PAGE4 drives MED12-mutant fibroid pathogenesis https://www.biorxiv.org/content/10.64898/2026.03.31.715552v1

Attomolar fecal cytokine profiling reveals gut immune dynamics and disease states https://www.biorxiv.org/content/10.64898/2026.03.31.714463v1

Estimation of chloroplast macromolecular complex copy numbers and subunit stoichiometries during the Chlamydomonas reinhardtii cell cycle https://www.biorxiv.org/content/10.64898/2026.03.30.715394v1

OmicGlaze: Spatial Multi-Omic Mapping of Traumatic Brain Injury https://www.biorxiv.org/content/10.64898/2026.03.30.715462v1

Equivalent fitness increase achieved by active learning-navigated habitat reconstruction and evolution-induced genome mutation https://www.biorxiv.org/content/10.64898/2026.03.29.715165v1

Protocol-dependent cardiomyocyte states determine disease modelling capacity of human iPSCs https://www.biorxiv.org/content/10.64898/2026.03.29.715135v1

Systems analysis of ribosomal CAR-site dynamics https://www.biorxiv.org/content/10.64898/2026.03.28.714829v1

From the lung to the muscle: Systemic insights from an integrative MultiOmics analysis of harbour porpoises in poor respiratory health https://www.biorxiv.org/content/10.64898/2026.03.28.714973v1

Competition between mitochondrial and cytosolic ribosomes produces a bistable metabolic switch https://www.biorxiv.org/content/10.64898/2026.03.30.715437v1

Treatment of murine autoimmune myocarditis with a novel monoclonal antibody that targets multiple inflammatory pathways https://www.biorxiv.org/content/10.64898/2026.03.27.714891v1

Environmental statistics and sensory experience shape patch foraging strategies in Drosophila larvae https://www.biorxiv.org/content/10.64898/2026.03.27.714746v1

A Cohort-Based Global Sensitivity Benchmark of MRI-Derived Whole-Heart Electromechanical Models in Healthy Hearts https://www.biorxiv.org/content/10.64898/2026.03.27.714701v1

Biological Time Equivalence in Vertebrates: Thermodynamic Framework, Comparative Tests, and Clade-Specific Deviations https://www.biorxiv.org/content/10.64898/2026.03.27.714731v1

A Systems Framework for Quantifying Programmability and Persistence Across Mammalian Cell Types https://www.biorxiv.org/content/10.64898/2026.03.27.714669v1

A Reproducible Dual-Model Constraint-Based Framework for Exploring Hepatic Energy Metabolism Under Stachys affinis-Derived Short-Chain Fatty Acid Scenarios https://www.biorxiv.org/content/10.64898/2026.03.26.714589v1

Targeting cancer-associated fibroblasts for treatment of ER+ breast cancer: A mathematical modeling perspective and optimization of treatment strategies https://www.biorxiv.org/content/10.64898/2026.03.27.714662v1

Linking Infection, Immunity, and Symptoms for Age-Dependent Influenza Severity https://www.biorxiv.org/content/10.64898/2026.03.26.714633v1

Actionable spatial prostanoid barriers constrain BiTE-driven adoptive T cell immunity in intact human tumors https://www.biorxiv.org/content/10.64898/2026.03.26.713601v1

Bimodal Coupling Optimization in Biological Rhythms: Balancing Energy Efficiency and Functional Demand https://www.biorxiv.org/content/10.64898/2026.03.25.713094v1

Glycan Reachability Analysis: A Bottleneck-Aware Frameworkfor Inferring Tissue-Specic Glycan Biosynthetic Potential fromTranscriptomics https://www.biorxiv.org/content/10.64898/2026.03.24.714093v1

Novel Oral LNAD+ Increases Intracellular NAD and Metabolic Flux Without Elevating Circulating NAD: Evidence from a Randomized Controlled Trial https://www.biorxiv.org/content/10.64898/2026.03.25.714130v1

An Integrated Analysis of GLP-1R Agonist Mechanisms: Addressing Study Variations in Heterogeneous Cell Systems https://www.biorxiv.org/content/10.64898/2026.03.25.714139v1

Cost-saving, trading, and internalization of externality: three economic strategies underlying amino acid archetypes of human metabolic enzymes https://www.biorxiv.org/content/10.64898/2026.03.25.714160v1

Combinatorial constraints predict that mitochondrial networks contain a large component https://www.biorxiv.org/content/10.64898/2026.03.25.714309v1

A trajectory-coupled network bottleneck governs gemcitabine resistance in 3D PDAC tissue models https://www.biorxiv.org/content/10.64898/2026.03.24.713885v1

MINGL Quantifies Borders, Gradients, and Heterogeneity in Multicellular Tissue Organization https://www.biorxiv.org/content/10.64898/2026.03.24.713296v1

Pan-cancer proteogenomic interrogation of the Ubiquitin Proteasome System https://www.biorxiv.org/content/10.64898/2026.03.23.713741v1

A metabolic model based on a pangenome core unveils new biochemical features of the phytopathogen Xylella fastidiosa https://www.biorxiv.org/content/10.64898/2026.03.23.713690v1

Distributed elasticity: a high-reward, moderate-risk strategy for efficient control modulation in insect flight https://www.biorxiv.org/content/10.64898/2026.03.23.713675v1

Proteomics for cultivated meat: the importance of Analytical Standardization https://www.biorxiv.org/content/10.64898/2026.03.23.713501v1

Quantifying Treatment Resistance in Mixtures of Gastrointestinal Stromal Tumor Cells with BARMIX https://www.biorxiv.org/content/10.64898/2026.03.23.713602v1

Agent-Based Modeling of Idiopathic Lung Fibrosis and Mechanistic Treatments https://www.biorxiv.org/content/10.64898/2026.03.22.713503v1

Barcoding biology: Chemotype predicts variation in genotype, physiology, and stress response https://www.biorxiv.org/content/10.64898/2026.03.22.713522v1

Cross-Species Translation Enhances the Use of Mouse Models for Translatability and Drug Discovery in Late-Onset Alzheimer's Disease https://www.biorxiv.org/content/10.64898/2026.03.21.713391v1

GlycoDiveR: a modular R framework to analyze and visualize highly dimensional glycoproteomics data https://www.biorxiv.org/content/10.64898/2026.03.21.713336v1

Systems-level longitudinal immune profiling reveals individualized immunotypes and genetic associations https://www.biorxiv.org/content/10.64898/2026.03.21.713378v1

A graph-based learning approach to predict the effects of gene perturbations on molecular phenotypes https://www.biorxiv.org/content/10.64898/2026.03.20.712202v1

Integrating metagenome-scale metabolic modelling and metabolomics to identify biochemical interactions in Microcystis phycospheres https://www.biorxiv.org/content/10.64898/2026.03.18.712574v1

Modeling the Role of Platelet-Released Polyphosphates in Tissue-Factor-Initiated Coagulation under Flow https://www.biorxiv.org/content/10.64898/2026.03.19.713007v1

FASTERCC: Accelerating Flux Consistency Testing and Context-Specific Reconstruction for Large-Scale Metabolic Network Models https://www.biorxiv.org/content/10.64898/2026.03.19.712885v1

Stochastic optimal control simulations of walking: potential and perspective https://www.biorxiv.org/content/10.64898/2026.03.19.712839v1

Circulating miRNA-Protein Signatures Predict Outcomes in Pediatric Dilated Cardiomyopathy https://www.biorxiv.org/content/10.64898/2026.03.17.712519v1

X-Cell: Scaling Causal Perturbation Prediction Across Diverse Cellular Contexts via Diffusion Language Models https://www.biorxiv.org/content/10.64898/2026.03.18.712807v1

Diverse high-fat diets drive multi-omic reprogramming that persists after dietary reversal https://www.biorxiv.org/content/10.64898/2026.03.17.708620v1

New perspectives in assessing environmental risks for birds: a simple TKTD framework to link growth and reproduction energy budget to chemical stress https://www.biorxiv.org/content/10.64898/2026.03.17.712277v1

A Multiscale Computational Architecture to Study Signaling Dynamics at Cell-Cell Interfaces https://www.biorxiv.org/content/10.64898/2026.03.16.712104v1

Interpretable machine learning meets systems biology to decode genotype-phenotype maps https://www.biorxiv.org/content/10.64898/2026.03.16.712082v1

MICA: Model-Informed Change-point Analysis https://www.biorxiv.org/content/10.64898/2026.03.16.712011v1

GeNETop: Context-Specific Genome-Scale Constrained Models Using Network Topology, Flux Variability, and Transcriptomics https://www.biorxiv.org/content/10.64898/2026.03.16.712013v1