bioRxiv SysBio
@biorxiv-sysbio.bsky.social
📤 892
📥 0
📝 2032
sRQA: AN INTEGRATIVE PIPELINE FOR SYMBOLIC RECURRENCE QUANTIFICATION ANALYSIS
https://www.biorxiv.org/content/10.64898/2026.03.31.715624v1
about 17 hours ago
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A phosphorylation switch in PAGE4 drives MED12-mutant fibroid pathogenesis
https://www.biorxiv.org/content/10.64898/2026.03.31.715552v1
about 17 hours ago
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Attomolar fecal cytokine profiling reveals gut immune dynamics and disease states
https://www.biorxiv.org/content/10.64898/2026.03.31.714463v1
about 19 hours ago
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Estimation of chloroplast macromolecular complex copy numbers and subunit stoichiometries during the Chlamydomonas reinhardtii cell cycle
https://www.biorxiv.org/content/10.64898/2026.03.30.715394v1
1 day ago
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OmicGlaze: Spatial Multi-Omic Mapping of Traumatic Brain Injury
https://www.biorxiv.org/content/10.64898/2026.03.30.715462v1
1 day ago
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Equivalent fitness increase achieved by active learning-navigated habitat reconstruction and evolution-induced genome mutation
https://www.biorxiv.org/content/10.64898/2026.03.29.715165v1
2 days ago
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Protocol-dependent cardiomyocyte states determine disease modelling capacity of human iPSCs
https://www.biorxiv.org/content/10.64898/2026.03.29.715135v1
2 days ago
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Systems analysis of ribosomal CAR-site dynamics
https://www.biorxiv.org/content/10.64898/2026.03.28.714829v1
3 days ago
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From the lung to the muscle: Systemic insights from an integrative MultiOmics analysis of harbour porpoises in poor respiratory health
https://www.biorxiv.org/content/10.64898/2026.03.28.714973v1
3 days ago
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Competition between mitochondrial and cytosolic ribosomes produces a bistable metabolic switch
https://www.biorxiv.org/content/10.64898/2026.03.30.715437v1
3 days ago
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Treatment of murine autoimmune myocarditis with a novel monoclonal antibody that targets multiple inflammatory pathways
https://www.biorxiv.org/content/10.64898/2026.03.27.714891v1
3 days ago
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Environmental statistics and sensory experience shape patch foraging strategies in Drosophila larvae
https://www.biorxiv.org/content/10.64898/2026.03.27.714746v1
4 days ago
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A Cohort-Based Global Sensitivity Benchmark of MRI-Derived Whole-Heart Electromechanical Models in Healthy Hearts
https://www.biorxiv.org/content/10.64898/2026.03.27.714701v1
4 days ago
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Biological Time Equivalence in Vertebrates: Thermodynamic Framework, Comparative Tests, and Clade-Specific Deviations
https://www.biorxiv.org/content/10.64898/2026.03.27.714731v1
4 days ago
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A Systems Framework for Quantifying Programmability and Persistence Across Mammalian Cell Types
https://www.biorxiv.org/content/10.64898/2026.03.27.714669v1
4 days ago
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A Reproducible Dual-Model Constraint-Based Framework for Exploring Hepatic Energy Metabolism Under Stachys affinis-Derived Short-Chain Fatty Acid Scenarios
https://www.biorxiv.org/content/10.64898/2026.03.26.714589v1
4 days ago
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Targeting cancer-associated fibroblasts for treatment of ER+ breast cancer: A mathematical modeling perspective and optimization of treatment strategies
https://www.biorxiv.org/content/10.64898/2026.03.27.714662v1
4 days ago
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Linking Infection, Immunity, and Symptoms for Age-Dependent Influenza Severity
https://www.biorxiv.org/content/10.64898/2026.03.26.714633v1
4 days ago
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Actionable spatial prostanoid barriers constrain BiTE-driven adoptive T cell immunity in intact human tumors
https://www.biorxiv.org/content/10.64898/2026.03.26.713601v1
4 days ago
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Bimodal Coupling Optimization in Biological Rhythms: Balancing Energy Efficiency and Functional Demand
https://www.biorxiv.org/content/10.64898/2026.03.25.713094v1
5 days ago
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Glycan Reachability Analysis: A Bottleneck-Aware Frameworkfor Inferring Tissue-Specic Glycan Biosynthetic Potential fromTranscriptomics
https://www.biorxiv.org/content/10.64898/2026.03.24.714093v1
7 days ago
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Novel Oral LNAD+ Increases Intracellular NAD and Metabolic Flux Without Elevating Circulating NAD: Evidence from a Randomized Controlled Trial
https://www.biorxiv.org/content/10.64898/2026.03.25.714130v1
7 days ago
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An Integrated Analysis of GLP-1R Agonist Mechanisms: Addressing Study Variations in Heterogeneous Cell Systems
https://www.biorxiv.org/content/10.64898/2026.03.25.714139v1
7 days ago
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Cost-saving, trading, and internalization of externality: three economic strategies underlying amino acid archetypes of human metabolic enzymes
https://www.biorxiv.org/content/10.64898/2026.03.25.714160v1
7 days ago
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Combinatorial constraints predict that mitochondrial networks contain a large component
https://www.biorxiv.org/content/10.64898/2026.03.25.714309v1
7 days ago
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A trajectory-coupled network bottleneck governs gemcitabine resistance in 3D PDAC tissue models
https://www.biorxiv.org/content/10.64898/2026.03.24.713885v1
7 days ago
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MINGL Quantifies Borders, Gradients, and Heterogeneity in Multicellular Tissue Organization
https://www.biorxiv.org/content/10.64898/2026.03.24.713296v1
7 days ago
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Pan-cancer proteogenomic interrogation of the Ubiquitin Proteasome System
https://www.biorxiv.org/content/10.64898/2026.03.23.713741v1
8 days ago
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A metabolic model based on a pangenome core unveils new biochemical features of the phytopathogen Xylella fastidiosa
https://www.biorxiv.org/content/10.64898/2026.03.23.713690v1
9 days ago
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Distributed elasticity: a high-reward, moderate-risk strategy for efficient control modulation in insect flight
https://www.biorxiv.org/content/10.64898/2026.03.23.713675v1
9 days ago
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Proteomics for cultivated meat: the importance of Analytical Standardization
https://www.biorxiv.org/content/10.64898/2026.03.23.713501v1
9 days ago
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Quantifying Treatment Resistance in Mixtures of Gastrointestinal Stromal Tumor Cells with BARMIX
https://www.biorxiv.org/content/10.64898/2026.03.23.713602v1
9 days ago
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Agent-Based Modeling of Idiopathic Lung Fibrosis and Mechanistic Treatments
https://www.biorxiv.org/content/10.64898/2026.03.22.713503v1
9 days ago
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Barcoding biology: Chemotype predicts variation in genotype, physiology, and stress response
https://www.biorxiv.org/content/10.64898/2026.03.22.713522v1
9 days ago
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Cross-Species Translation Enhances the Use of Mouse Models for Translatability and Drug Discovery in Late-Onset Alzheimer's Disease
https://www.biorxiv.org/content/10.64898/2026.03.21.713391v1
10 days ago
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GlycoDiveR: a modular R framework to analyze and visualize highly dimensional glycoproteomics data
https://www.biorxiv.org/content/10.64898/2026.03.21.713336v1
10 days ago
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Systems-level longitudinal immune profiling reveals individualized immunotypes and genetic associations
https://www.biorxiv.org/content/10.64898/2026.03.21.713378v1
10 days ago
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A graph-based learning approach to predict the effects of gene perturbations on molecular phenotypes
https://www.biorxiv.org/content/10.64898/2026.03.20.712202v1
11 days ago
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Integrating metagenome-scale metabolic modelling and metabolomics to identify biochemical interactions in Microcystis phycospheres
https://www.biorxiv.org/content/10.64898/2026.03.18.712574v1
11 days ago
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Modeling the Role of Platelet-Released Polyphosphates in Tissue-Factor-Initiated Coagulation under Flow
https://www.biorxiv.org/content/10.64898/2026.03.19.713007v1
11 days ago
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FASTERCC: Accelerating Flux Consistency Testing and Context-Specific Reconstruction for Large-Scale Metabolic Network Models
https://www.biorxiv.org/content/10.64898/2026.03.19.712885v1
13 days ago
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Stochastic optimal control simulations of walking: potential and perspective
https://www.biorxiv.org/content/10.64898/2026.03.19.712839v1
13 days ago
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Circulating miRNA-Protein Signatures Predict Outcomes in Pediatric Dilated Cardiomyopathy
https://www.biorxiv.org/content/10.64898/2026.03.17.712519v1
14 days ago
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X-Cell: Scaling Causal Perturbation Prediction Across Diverse Cellular Contexts via Diffusion Language Models
https://www.biorxiv.org/content/10.64898/2026.03.18.712807v1
14 days ago
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Diverse high-fat diets drive multi-omic reprogramming that persists after dietary reversal
https://www.biorxiv.org/content/10.64898/2026.03.17.708620v1
15 days ago
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New perspectives in assessing environmental risks for birds: a simple TKTD framework to link growth and reproduction energy budget to chemical stress
https://www.biorxiv.org/content/10.64898/2026.03.17.712277v1
15 days ago
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A Multiscale Computational Architecture to Study Signaling Dynamics at Cell-Cell Interfaces
https://www.biorxiv.org/content/10.64898/2026.03.16.712104v1
16 days ago
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Interpretable machine learning meets systems biology to decode genotype-phenotype maps
https://www.biorxiv.org/content/10.64898/2026.03.16.712082v1
16 days ago
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MICA: Model-Informed Change-point Analysis
https://www.biorxiv.org/content/10.64898/2026.03.16.712011v1
16 days ago
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GeNETop: Context-Specific Genome-Scale Constrained Models Using Network Topology, Flux Variability, and Transcriptomics
https://www.biorxiv.org/content/10.64898/2026.03.16.712013v1
16 days ago
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