🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x

How can we use cell shapes and geometry to study mechanics of tissues? I'm @juliaeckert.bsky.social, and with this thread, I would like to show you the secrets of cells and tissues. Let’s connect biology with a little bit of physics. Don't be scared and get inspired 😀. #EpithelialMechanics

Our new collection offers cell biologists practical, expert-driven guidance and best practices in the design, execution, and analysis of experiments, and the subsequent communication of their results to their peers. 👉 rupress.org/jcb/collecti... #Reproducibility

Happy to share a new publication: an introduction to comparative oncology in @natrevcancer.nature.com‬. Thanks to the leaders in the field for welcoming me as an invertebrate researcher. rdcu.be/etKdN

Epithelial morphogenesis is all about how epithelial tissues develop unique shapes and structures! I'm @nehaghosh.bsky.social and will share some research in this area.

A Drosophila single-cell 3D spatiotemporal multi-omics atlas unveils panoramic key regulators of cell-type differentiation: Cell 1/2 www.cell.com/cell/abstrac...

FINALLY out in #Science Advances! 🎉 3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author! It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀 www.science.org/doi/10.1126/... #DevBio #CellBio #Microscopy

extremely happy to present the final version of our "smurf mice" paper www.biorxiv.org/content/10.1..., led by Céline Cansell when she was a postdoc in my group (now an independent @inrae-france.bsky.social researcher). Disclaimer: no blue mice here alas BUT clearly a biphasic ageing process

A reminder in these hard times. #sciencestrong

My first post on Bluesky! Very excited to share our work just published in @science.org. We find that “Interphase cell morphology defines the mode, symmetry, and outcome of mitosis” - in angiogenesis and other tissues! www.science.org/doi/abs/10.1... www.science.org/doi/abs/10.1...

#EDRC2025 👇🏻👇🏻👇🏻👇🏻

Interested in Developmental Mechanics??? We are organizing a mechanobiology workshop in Baeza, Spain, October 21-23, 2025. Come join us (and please help us spread the word)!!!

#CellMigration 𝐢𝐧 𝐯𝐢𝐯𝐨! Excited to share this video on #FluorescenceFriday 🌈 Today as a GIF to circumvent video compression 😅! Migratory Nascent Myotubes on #Drosophila Testes. Marker: Lifeact-eGFP. Scope: 980 Airyscan (@zeiss-microscopy.bsky.social) #cellbio #sciart #devbio #science #microscopy

Cell and developmental biologists: as you start looking at conferences in 2025, consider joining us at the 2025 Cell Contact & Adhesion GRC. We've assembled a strong and diverse program of speakers at the cutting-edge of science in our field 1/n Please repost www.grc.org/cell-contact...

1/14 “Epithelial” & “Mesenchymal” aren’t binary categories—they form a spectrum, or better yet, a multidimensional space. This becomes especially clear in collective cell migration, which often depends on a finely tuned degree of “mesenchymal-ness”. #cellbio #devbio #cellmigration

I'm happy to share our study “Proximity-based activation of AURORA A by MPS1 potentiates error correction” now published at @currentbiology.bsky.social www.sciencedirect.com/science/arti... It describes a new way kinetochores and centrosomes communicate to ensure accurate chromosome segregation.

If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social

Same for ZFIN! @zfinmod.bsky.social put them in your papers' acknowledgements and cite them (Bradford et al. 2022 academic.oup.com/genetics/art...)

We’re excited to share our work where we investigated the mechanisms of chromosome motion by tracking all #chromosomes, mapping their interactions, and live cell karyotyping, using #AI based denoising, segmentation and registration, published in Nature Cell Biology. www.nature.com/articles/s41...

Genetically encoded reporters of actin filament organization in living cells and tissues: Cell www.cell.com/cell/fulltex...

Great team effort from our SGR group “REGnetREG” . Find out more by downloading this review 👇🏻👇🏻👇🏻

⭐️ Please Fwd. Are you in Paris on 16th May? See👇 poster of symposium on « Information processing in biological systems » @collegedefrance.bsky.social Fantastic line of speakers 🤩. It is free, w/o registration, and it will be exciting.m! Follows from my series of lectures at CdF last fall.

1/35 New paper out! @jamesTstroud and I dive into why long-term studies are crucial for understanding evolution. They reveal processes impossible to detect in short timescales and capture rare events that transform our understanding of evolutionary dynamics. www.nature.com/articles/s41...

Happy to share our review on methodology for measuring and manipulating mechanical forces with specific focus on developmental biology! Congrats to authors @clemvilleneuve.bsky.social @mccreery.bsky.social and hats off to the community for developing awesome tools www.nature.com/articles/s41...

This dot is a region that intersect multiple cell junctions in an epithelia. These dots act as tiny anchors of cell contacts and they’re critical for epithelial coherence during homeostasis AND development. I’m @katecavanaugh.bsky.social and I’ll be your guide on this 🧵 about tricellular vertices.

Registration is open for the 2025 iteration of the wonderful @EMBOevents workshop on cell polarity and membrane dynamics #EMBOcellPolarity25 I am organizing with Ed Munro! Wonderful lineup wonderful please please sign up and share! meetings.embo.org/event/25-cel...

Unique opportunity to join the CytoMorpho Lab (in Paris ❤️) as a postdoc to work on the self-organization and polarization of reconstituted networks made of microtubules, motors and actin filaments in vitro. Experience required. Please Repost 🙏 thanks !

New paper alert! ‼️‼️ Super happy to share that my postdoc paper is finally out! 1/3 We looked at scaling of chromosome separation during anaphase in zebrafish embryos.

Don’t forget to apply! This is an amazing opportunity!

1. A thread about the value of doing "slow science": When I was in grad school I heard this (likely apocryphal) story about one of my favourite scientists: Barbara McClintock.

As we're entering the last month for registering the FlyJEDI meeting 2025 shorturl.at/8VO7A I am happy to share with you that the event is now sponsored by @fly-eds.bsky.social @ijmonod.bsky.social Many thanks for supporting the community's reboot. Join us to build a strong research community!

I put together a small guide on how to get started with Fiji. Please distribute to anyone who might benefit form this! zenodo.org/records/1477... #imageanalysis #fiji #imagej #training

Wow! We got the cover! #MBOC #ASCB #CellBio So proud of #TeamTestis. Screening <270 lines for shape defects was a huge team effort! I created this collage from the team’s images from the past 2 years! Depth-color-coded with Fiji. Inspired by late 19th century lithographic animal illustrations.

Porto is a beautiful during spring (it is all year around but I may be biased)! And is hosting the conference that you don't want to miss on #adhesion regulation in #cancer. A great lineup of speakers from basic to clinical research and also many talk opportunities. Check it out and join us!

Support a fantastic society journal by submitting your insect physiology work to @royentsoc.bsky.social PHEN. In the upcoming January volume, we discuss some of the key questions for future research in physiological #entomology. #symbiosky 🐜🐝🦋🦟🧪 resjournals.onlinelibrary.wiley.com/share/YJQDXW...

My regular reminder that there is an open call @pasteur.fr for junior group leader covering various axis (including topics related to development biology), open till Feb. 28th. Don't hesitate to DM me or reach out by email if you want to get more context. research.pasteur.fr/fr/call/call...

Very excited that the lab's first paper is out! We showed that in stem cells, Aurora B controls abscission dynamics by regulating microtubules stability and MCAK recruitment. Very happy with this streamlined version of our 2024 preprint. www.cell.com/cell-reports...

Every once in a while we publish a paper that moves a whole field forward. I think that's the case for this one from the Bugaj lab, where they describe proteins for THERMOGENETIC control of cellular behavior. www.nature.com/articles/s41...

It seems that many labs make only incomplete use of the three steps of our #Drosophila genetic training, which includes the manual, the PPT and the tasks. See explanations and downloads here: sites.manchester.ac.uk/fly-facility...

It's always mesmerizing seeing how these group of cells move. ℹ️Border cells invading through nurse cells ℹ️Drosophila S9 egg chambers

Yamini @yamini-ravichan.bsky.social changed the topology of Hydra to show that actin orientational defects of Hydra induce the full program of head regeneration: www.science.org/doi/10.1126/... Mechanics controls development! Thanks to Dan Pearce, Karsten Kruse, Matthias Vogg & Brigitte Galliot.

Paper published!!! Tremendous work by Gordana Scepanovic, with key contributions by @negberry.bsky.social and @krothphd.bsky.social. We ask why is mTor signalling necessary for rapid wound repair. 🧪 #drosophila #devbio Share link: authors.elsevier.com/a/1kS2e5Sx5g...

Or what about the #Drosophila computer game? Loads of stuff that I almost forgot about: scratch.mit.edu/projects/744...

How oncogenic clones can eliminate their neighbours to take over space ? There are different ways combining growth and interfacial tension induced compaction. Check out our latest preprint led by Léo Valon and Alexis Matamoro-Vidal to learn more about this 👇 www.biorxiv.org/content/10.1...

NEW PAPER: The essential adherens junction component alpha-catenin is regulated during #mitosis. For those who can’t get enough adhesion protein biology, a 🧵: 1/10 journals.biologists.com/bio/article/...

Cells are full of protein machines. Most don’t act alone, but instead form part of larger multiprotein complexes. For example, epithelial tissues & organs assemble by virtue of the multiprotein machines mediating cell-cell adhesion or adhesion of cells to the underlying extracellular matrix 1/n 🧪

Planning your summer science adventures? Join us at this amazing Gordon Conference in the Swiss Alps. Follow this thread for the diverse topics and speakers already on board, and we're starting to look at abstracts for more invited talks! Please re-post

Dear Droso peeps, we re-announce the upcoming JEDI meeting that will take place at Château du Feÿ from June 3rd to 5th in 2025. You'll find a prelim program flies-jedi.github.io/projects/202... We're hoping to gather about 45 of more or less young droso PI to reboot the community. -> Register Now!

Read below for the latest from Emily Ho in my lab on in vivo receptor tyrosine kinase biosensors. This has been a *dream* project, seeing endogenous RTK activity in live embryos for the first time. Surprise: they don't always match those of downstream signaling pathways!