New @pnas.org "This work represents the most extensive study to date regarding the effect of tattoo ink on the immune response and raises serious health concerns associated with the tattooing" including reduced response to Covid vaccination www.pnas.org/doi/10.1073/...

Check out my Perspective article “The Retina’s Rhythm” which accompanies an exciting paper by Claude Desplan in Science. I highlight his discovery that waves of calcium are required to finalize the honeycomb-like structure of the Drosophila retina. www.science.org/doi/epdf/10....

Super proud to be part of SFB1348 — and excited to share that I now officially have my own lab in Münster! 🎉🪰 We’ll study #cellbio & #morphogenesis, focusing on organ sculpting and #chirality in #Drosophila. I’ll soon hire my first #PhD student — feel free to reach out! #juniorPI #Science #devbio

Well deserved, Ben! 🎉

Congrats Ben, Claude, et al! A beautiful characterization of roles of Ca++ waves and gap junction functions in tissue patterning! www.science.org/doi/10.1126/...

Attempt number seven at uploading this video of intermediate filaments in an enormous COS7 cell. I have a feeling the BlueSky compression will not do it any favors.

I am very excited to be organizing a session for postdocs (with focus on those in the job market). Be on the lookout for info and registration! 🐟🧪

SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT

#aECM Cub starts next week Nov 18 with talks on patterning the Drosophila lens, mouse tectorial membrane, and C.elegans cuticle furrows. You can still sign up for access using the link below.

How do four-eyed fish see above & underwater? 🌤️🌊 Our new preprint reveals how Anableps rewired its retina for dual vision- evolution at work 👁️👁️ Kudos to @perezlouise.bsky.social @josanesousa.bsky.social @keylapruett.bsky.social + team! 🔗 tinyurl.com/3a8r9xy5

Development that lasts a life time. Check out the 2025 special issue of @dev-journal.bsky.social on Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues journals.biologists.com/dev/issue/15...

Required reading for cell biologists to get a sense of basic statistical principles! www.nature.com/articles/s41...

Vinculin is a simple adapter protein right? Wrong! That’s been the prevailing view for the 46 years since it was discovered. Here we provide a new paradigm and show that vinculin is a complex mechanosensor itself, containing 6 binary switch domains. www.science.org/doi/10.1126/...

An absolute stunner!

Excited to announce the final version of the Mosquito Cell Atlas is out now in @cellpress.bsky.social!! 🦟🩸 There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields! www.cell.com/cell/fulltex...

The ECM is no longer in the back seat when it comes to development. Check out our special issue "Dynamics of the extracellular matrix in development, cell physiology and disease" with 8 selected articles to learn more: A 🧵 www.sciencedirect.com/special-issu...

Ascidians (Ciona intestinalis)🪸Our distant chordate cousins! 🌊 Simple sea squirts that reveal how vertebrate body plans evolved 🧬 A key model for notochord formation, neural induction, and cell lineage mapping 📸 Video by MBL Embryology 2019 #ModelMonday #DevBio #EvoDevo

A developmental atlas of zebrafish gills links early vascular patterning to adult architecture Read this #LifelongDevSI #OA Research Article by Mathieu Preußner @mathpreu.bsky.social, Virginie Lecaudey @vlecaudey.bsky.social and colleagues: journals.biologists.com/dev/article/...

A key role for Canoe's intrinsically disordered region in linking cell junctions to the #cytoskeleton. New study from Corbin Jensen, Mark Peifer (@peiferlabunc.bsky.social) and colleagues @unclineberger.bsky.social: rupress.org/jcb/article/... #Development #Adhesion #Drosophila

What is a promoter? And how does it work? We very happy to share our latest work trying to understand enhancer-promoter compatibility. I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters www.biorxiv.org/content/10.1...

🎉🎉 We finally have a website! 🎉🎉 Did you miss a thread? Want to know who our delegates are? Do you want to join our big club? Check it out: epithelialmechanics.github.io Huge thanks to all thread-contributors and to you for following us!

How can we see the cells that make up a living organism? Membrane-localising tags can drive fluorescent proteins to the cell's outer membrane, making their outlines visible. But the tags don't work well in all organisms. How do you find one for your species of interest? 🧵 Check our latest preprint

1/9 Thrilled to share that our paper, “Origin of Ewing sarcoma by embryonic reprogramming of neural crest to mesoderm,” is now published in @cp-cellreports.bsky.social! @amatrudalab.bsky.social @crumplab.bsky.social www.cell.com/cell-reports...

So excited to announce lab alumni Dr. Helen Mengze He and Liana Boraas work at @yalecvrc.bsky.social in collaboration with the Kaelyn Sumigray lab @yaleschoolofmed.bsky.social is published today in @natcomms.nature.com and highlighted in Yale News! medicine.yale.edu/news-article...

Menstruation- a natural regenerative process in women, yet understudied and under discussed. But, this phenomenal work is a start for making all the difference 🎉

Happy to share our new study @ijmonod.bsky.social and @mpi-scienceoflight.bsky.social with C. Duclut and J. Prost. on forces generated by active fluid transport in epithelia and their role in tissue dynamics. Congrats to Huiqiong Wu, G. Arkowitz and R. Chilupuri! www.biorxiv.org/content/10.1...

Delighted to announce the publication of our manuscript today in @natcomms.nature.com showing how desmosomes sense and respond to mechanical cytoskeletal forces. Led by the truly amazing Belle Dong with many thanks to our collaborators in the Choy & Kwiatkowski labs. rdcu.be/eKpbL

Excited & looking forward to this conference on development & regeneration! Delighted to be a part of this stellar lineup of speakers! Early bird registration closes soon! snuadmissions.com/cmmdr/cmmdr2... #devbio #regeneration #stemcells #homeostasis

How are tissue folds stabilized during animal organ development? Our latest preprint helps to answer this question, using the fruit fly wing disc as a model doi.org/10.1101/2025.... @poldresden.bsky.social @mpipks.bsky.social @dfg.de @janafuhrmann.bsky.social @vicioms.bsky.social @mbisg.bsky.social

Happy #FluorescenceFriday! This is a maximum intensity projection of depth shaded actin (🌈) in a section from an E9.5 🐭 neural tube (NT). 🔬 by postdoc @christinaadaly.bsky.social 👩‍🔬 🧪 Image shows the floor plate and lumen of the developing NT. #SciArt #DevBio #DevNeuro

I am thrilled to share our latest story led by the incredibly talented Brooke D’Arcy and Camila Musso. We discover a rich world of local gene expression in radial glia, essential neural and glial precursors, and develop a new method for sub-cellular mRNA manipulation. www.biorxiv.org/content/10.1...

New preprint from the lab! We discovered a transient fluidization in the basal region of human forebrains by tracking microdroplets in cerebral organoids.This “basal fluidization”, absent in gorilla and mouse, may contribute to greater surface expansion in human forebrains 1/ doi.org/10.1101/2025...

Delighted that Ziqi Dong's PhD paper is out for all to read! Hypoxia is fundamental to normal development, and fascinating! Thanks to all of our co-authors including @jamesnathanlab.bsky.social @jellevda.bsky.social authors.elsevier.com/sd/article/S...

I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉 @karalmckinley.bsky.social We built the first transgenic model of menstruation in mice. We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪 www.biorxiv.org/content/10.1... 🧵

Very excited about this project: we believe that 3D anatomical atlases have a huge potential for developmental biology. As a starting point, we made the first ever Drosophila wing disc atlas!

Fwd: Fwd: “I hope this email finds you well”

John Clarke, Michel Devoret and John Martinis have been awarded the 2025 Nobel Prize in Physics for demonstrating quantum physics on the macroscopic scale go.nature.com/3WnEUhE

Issue 18 is complete! On the cover: Clones on Drosophila retina with activated Mbt kinase (pink), expanding Sdk protein (yellow) from tri- to bi-cellular adheren junctions & distorting the ommatidial lattice (cyan). See Research Article by Gandhi et al. journals.biologists.com/dev/article/...

Congratulations to Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi for this year's Nobel Prize in Physiology or Medicine. It also demonstrates the fairness of the prize, as Mary Brunkow is a Senior Program Manager (not a professor) at the @isbscience.org hood.isbscience.org/people/mary-...

I absolutely loved reading this one recently! The authors show how AMPK (which is traditionally viewed as an stress-activated kinase) is also developmentally regulated by circulating adenosine levels in Drosophila. www.nature.com/articles/s41...

Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd

It's online! In this series of perspectives @dev-journal.bsky.social, yours truly talks about the exciting open questions and many things to do in the field of dev bio and neuroscience #DevBio🧪 #PIsOfTomorrow journals.biologists.com/dev/article/...

Latest from ours: www.cell.com/cell-reports... This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵

🚨 New preprint! We profile the transcriptome of the C. elegans distal tip cell: a persistent leader cell that invades basement membrane to shape the gonad. Our dataset defines the molecular signature of invasive leader cells & uncovers new regulators of collective cell invasion.

Mechanical constraints disrupt gastruloid polarisation without changing gene expression - uncouples morphogenesis & patterning Gregor & co use tunable hydrogels to show cell motility, not gene expression, drives axis formation in gastruloids journals.biologists.com/dev/article/...

Jane Goodall, who revealed the intimate lives of chimpanzees and gave the modern world a language of hope, has died at the age of 91. “Every individual matters. Every individual has a role to play. Every individual makes a difference,” she told audiences. Those words remain her truest epitaph.

How exercise promotes the immune system vs cancer, working through a gut bacteria metabolite www.cell.com/cell/abstrac...

Cool Postdoc opportunity alert! UNC SPIRE (Seeding Postdoctoral Innovators in Research & Education)-it provides scholars with both high quality research training & the opportunity to develop research based teaching skills that will inspire students across the sciences 1/n spire.unc.edu/program-info/

See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...

This is very exciting! A small clinical trial using gene therapy for Huntington's disease has been successful. microRNAs were used to edit the Huntington mRNA, stopping it making mutant protein that can damage neurons. Huge hopes now for treating such a devastating condition