A new review explores how #AI and longitudinal #multiomics data could detect early transitions from wellness to disease — transforming healthcare from reactive to proactive. It’s a shift from single biomarkers to dynamic, systems-level health trajectories. 🔗 isbscience.org/news/cancer/...

Check out our review on emerging technologies for diet tracking in Nature Food. 👇 This paper was led by @catalinacuparencu.bsky.social, with @cdiener.com and others: www.nature.com/articles/s43... @isbscience.org @uwbioe.bsky.social @uwgenome.bsky.social

What does a “healthy” bathroom routine actually look like? @isbscience.org microbiome researcher Dr. Sean Gibbons explains the science — from frequency to stool form — in a quick 11-minute podcast. Short, smart, and very listenable. @gibbological.bsky.social podcasts.apple.com/ca/podcast/d...

Before we stop crossing out 2025 and remembering to write 2026 at the top of our lab notebooks, check out all that our Seattle institutes accomplished in 2025! 🎉 @isbscience.org: https://bit.ly/4su411j BBI: https://bit.ly/49fJZ30 @fredhutch.org: https://bit.ly/4qJf5Wi KPWHRI: https://bit.ly/4su5Fjv

Pooled CRISPR screens with transcriptomics readout arrived for bacteria. We introduce mapSPLiT, an approach to profiling transcriptional responses to CRISPR perturbations at scale. Collaborative work with Carothers, Zalatan, and Seelig groups at UW&@isbscience.org www.biorxiv.org/content/10.6... 1/4

🥉 Taking the #3 spot in our 2025 Post Countdown is the @isbscience.org Virtual Microbiome Symposium! Don't worry if you missed out, the full recap is online: https://bit.ly/4qeNDQ4 https://bsky.app/profile/scienceinseattle.com/post/3m5wob373ce2k

Celebrating the complex beauty of the season. ❄️🧬 From all of us at ISB, have a wonderful holiday and a Happy New Year!

2025 was a milestone year for ISB. We didn't just look back at our 25-year legacy; we used it to launch discoveries that will shape the future of health. In our 2025 Year in Review, explore the science and the successes that made the past 12 months truly historic. isbscience.org/news/our-peo...

Another banner year for the Gibbons Lab. Great job, @gibbological.bsky.social!

💡 Curious how your gut microbes talk to your brain, immune system, and hormones? @isbscience.org's 2025 Virtual Microbiome Symposium explored these questions with leaders in the field — over 1,000 attendees worldwide registered. Catch the highlights and full sessions: isbscience.org/news/health/...

@isbscience.org postdoc @n8ritz.bsky.social (Venkatesh Lab) was selected as a 2026 WRF Postdoc Fellow. The fellowship supports early-career researchers pursuing high-impact science. Congrats Nate! 🎉 @flash-point.bsky.social More: tinyurl.com/y772pr2j Venkatesh Lab: venkatesh.isbscience.org

If you missed the 2025 @isbscience.org Virtual Microbiome Symposium (theme: how microbial metabolites influence the brain, the immune system, & metabolism), the videos of the talks and the panel discussion are now available here: youtube.com/playlist?lis... Thanks to all who helped make it happen!

Nearly 1,000 people have registered so far! Don't miss out!

Top #Citations 2025: 9️⃣🧪 @cdiener.com @gibbological.bsky.social et al ( @isbscience.org @medunigraz.at#Citations) present a new method to estimate dietary intake from human stool by detecting food-derived DNA in faecal metagenomes.

Did you miss @isbscience.org's Mary Brunkow give her Nobel lecture bright and early on Sunday morning? You can watch Mary and her co-Nobel Prize recipients here: www.youtube.com/watch?v=n1tf...

Had fun presenting in London last month on our microbiome-aging work, and spoke with Olivia Haslam afterwards about how we're thinking about moving forward with microbiome-informed precision nutrition to support healthy aging. @isbscience.org www.nutraingredients.com/Article/2025...

ISB received a 2025 AWS Imagine Grant! 🙌 It's full steam ahead for Tarpon — our AI platform turning T-cell receptors into digital immune fingerprints. This kind of tech + biology mash-up could reshape how we understand disease and design future immune therapies. isbscience.org/news/press-r...

Hear, hear!

On #GivingTuesday, we’re spotlighting the bold, early-stage science that shapes future breakthroughs. Your support helps @isbscience.org push new ideas forward — and expands access to STEM education for the next generation. Give today: give.isbscience.org

#Multidomain therapy for #AlzheimersDisease: a scoping review of #cognitive decline trials Jared C. Roach, Gwênlyn Glusman, Molly K. Rapozo... Leroy Hood @isbscience.org link.springer.com/article/10.1...

Please join us on Dec 12th for the 2025 @isbscience.org Virtual Microbiome Symposium, focused on "Gut Microbial Metabolites and Their Impact on Host Systems". Co-organized by @gibbological.bsky.social Registration is free & we have a fantastic line-up of experts! isbscience.org/events/2025-...

Meet Lina Yang! Lina is a junior at Shorecrest HS in WA who participated in our System Thinkers in STEM Ambassadorship. Check out Lina’s STiSA project: see.isbscience.org/projects/lin... #STEMsystemsthinkers @isbscience.org

New: PNW RECOVER Long COVID Update — @isbscience.org's Jim Heath, @uwmedicine.bsky.social's Helen Chu & Swedish's Jason Goldman shared new insights on #longCOVID symptom trajectories, clinical trial findings, and upcoming treatment studies. Recap + full video: isbscience.org/news/isb-eve...

🦠 The @isbscience.org Virtual Microbiome Symposium is on December 12, 2025! This virtual symposium will dive into the influence of gut microbial metabolites on human #physiology. This event is perfect for everyone in academia, industry, and the clinic. Register now: https://bit.ly/4oe67iw

📸Check out photos from our most recent Dean’s Distinguished Lecture Series on Nov. 12 with Leroy Hood, MD, PhD, CEO of Phenome Health and professor at both the Buck Institute for Research on Aging and @isbscience.org. flic.kr/s/aHBqjCACug #UCIMedSchool #UCIrvine #UCI @ucirvine.bsky.social

Congrats to @gibbological.bsky.social, named a 2025 @clarivate.com Highly Cited Researcher for the fourth consecutive year. A clear reflection of the reach and influence of his work in #microbiome science. Full list: clarivate.com/highly-cited...

Join @isbscience.org on December 12 for a Virtual Microbiome Symposium highlighting new discoveries about how gut-derived metabolites affect neural, immune, and endocrine systems. Open to microbiome-curious researchers and practitioners everywhere. isbscience.org/events/2025-...

Dr. @erictopol.bsky.social & Dr. Lee Hood explore the future of #longevity & #prevention in a virtual conversation centered on Super Agers. Dive into the recording for deep insights on #genomics, #AI, #lifestyle, and #equity in #health. isbscience.org/news/health/...

One week to go! @isbscience.org's Dr. Lee Hood joins Dr. @erictopol.bsky.social, author of Super Agers, for a live virtual chat on the science and innovation redefining how we age. 🗓 Nov. 4 | 10–11 a.m. PT 💻 Free registration: isbscience.zoom.us/webinar/regi...

ISB's Dr. Cory Funk was a guest on the Optispan Podcast and sifts through why hundreds of #Alzheimers drugs have missed the mark – and what actually moves the needle – turning hard lessons into practical takeaways for patients, clinicians, and researchers. www.optispan.life/podcast/v/jl...

Great primer from #NobelPrize winner Dr. Mary Brunkow on @npr.org's Here & Now: how FOXP3 and T regs help keep the immune system from harming the body. (~6 min) @wbur.org 🎧 www.wbur.org/hereandnow/2...

“Spam? Or… Nobel?” Hear the moment and see our Nobel Prize hub: isbscience.org/nobel

Two leading voices in medicine – Lee Hood and Eric Topol – will explore what it means to live longer and healthier in a free virtual conversation hosted by @isbscience.org. 🗓️ November 4, 10-11 a.m. PT 💻 Register here – isbscience.zoom.us/webinar/regi... #Longevity #DigitalHealth #SuperAgers

Rubbing shoulders with a @nobelprize.bsky.social laureate! 🤩What a week! Couldn’t have happened to a nicer person: isbscience.org/news/press-r... @isbscience.org @naehasubramanian.bsky.social @flash-point.bsky.social @annabiosys.bsky.social

Dr. Mary Brunkow is a 2025 Nobel laureate. In today’s @isbscience.org press conference, she shares the FOXP3 story, from a puzzling mouse to a discovery that reshaped immunology. 🎥 Watch the full video: youtu.be/vg61fbycGEk

This morning, @isbscience.org's Dr. Mary Brunkow was awarded the 2025 Nobel Prize in Physiology or Medicine! Dr. Brunkow shares the award with Fred Ramsdell and Shimon Sakaguchi. Read the press release here: www.nobelprize.org/.../medicine.... What a tremendous honor! Congratulations!

Many congratulations, Mary Brunkow! Couldn’t be happier for you and @isbscience.org ! ♥️ www.nobelprize.org

Congratulations to Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi for this year's Nobel Prize in Physiology or Medicine. It also demonstrates the fairness of the prize, as Mary Brunkow is a Senior Program Manager (not a professor) at the @isbscience.org hood.isbscience.org/people/mary-...

Congratulations! The🏅2025 #NobelPrize in Physiology or #Medicine is awarded to 🇺🇸 Mary E. Brunkow ( @isbscience.org ), 🇺🇸 Fred Ramsdell (Sonoma Biotherapeutics) and 🇯🇵 Shimon Sakaguchi (Osaka University) for their insights into how our #immunesystem is kept from attacking our own body.

Join us for Ignite STEM at @isbscience.org: 11/6, 6-8pmPT. Celebrating 25 years of ISB Education with stories from teachers & students, time with scientists, and the Valerie Logan Leadership in Science Education Award. 🎟 $25 | Students free | 🚗 Free parking Register: isbscience.org/events/ignit...

Remembering Dr. Charles “Chuck” Watts (1942–2025). Our tribute: isbscience.org/news/philant...

It’s #PostdocAppreciation Week! @isbscience.org Postdoc Dr. Dmitry Sutormin found gut bacteria form 3 guilds: Stressors Metabolizers Growers A survival “bet-hedging” strategy that helps them adapt. 🎥 Watch Dmitry explain: youtu.be/5LG_Ae0SiFg

Congratulations to Co-founder Dr. Lee Hood, who has been awarded the Michael Sela Prize in Biomedical Sciences by the Weizmann Institute of Science. Dr. Hood, along with Drs. Francis Collins and Eric Lander, are the recipients of the inaugural prize. isbscience.org/news/press-r....

Postdocs are the pulse of ISB. They bring passion, vision, and fresh ideas that drive discovery. In honor of Postdoc Appreciation Week, hear from our postdoctoral fellows and learn more about ISB’s Postdoc Program. isbscience.org/news/philant...

Congratulations to ISB Co-founder and Professor Dr. Leroy (Lee) Hood for receiving the 2025 Michael Sela Prize in Biomedical Sciences! 🎉 A well-deserved honor for a truly inspiring pioneer in human health and medicine. 🧬✨ Learn more: www.weizmann.ac.il/sela-prize/

Since 2021, Claudia McLaughlin Ludwig @claudiamcl.bsky.social and ISB Education have partnered with AmeriCorps. Join recent @americorps.bsky.social members Sarah Clemente and Faduma Hussein in reflecting on their time at ISB and the importance of this program to their professional development.

Join @ucirvine.bsky.social School of Medicine for the Dean’s Distinguished Lecture Series with Leroy Hood, MD, PhD, CEO of Phenome Health 📊⚕️ Topic: “How Your Data Can Transform Your Health” 📅 Nov. 12, 7 to 8 p.m. 📍 The Susan & Henry Samueli College of Health Sciences, Irvine, CA 👉 bit.ly/3JyftH4

Great pop-sci digest by Alex Carr of his recent C. diff modeling work in Cell Systems youtu.be/shp-TjniW48?... here's the paper --> doi.org/10.1016/j.ce... @isbscience.org

ISB Associate Professor Dr. Sean Gibbons @gibbological.bsky.social was a guest on the Longevity Roadmap podcast, where he discussed the challenges of modifying the microbiome, the potential of precision nutrition, the emerging field of fecal transplants, and more. www.youtube.com/watch?v=MP0o...

🦠 @isbscience.org researchers have developed personalized models to predict C. difficile colonization risk and test probiotics, paving the way for precision #microbiome therapies. Learn more from Drs. Sean Gibbons, Alex Carr, Nitin Baliga, & Christian Diener: bit.ly/46QGAqs