🔥PCOS has long been framed as a reproductive disorder. This review makes a compelling case that it’s fundamentally metabolic: androgen excess doesn’t just disrupt ovulation, it acts on the brain, liver, fat, pancreas, and muscles to drive obesity, insulin resistance, and metabolic disease. #science

New expert guidance on the pharmacological management of obesity from The Obesity Society, Obesity Medicine Association, and the Obesity Action Coalition. Created alongside patient advocates to strengthen evidence-based, person-centered treatment. 🧪 onlinelibrary.wiley.com/doi/full/10....

A microbiome gut-brain pathway influenced by intestinal metabolites, innate immune responses, vagal nerve signaling and hippocampal memory encoding, impacts the rate of cognitive decline. Many potential points of intervention are described. #Science 🧪

Our metagenomic diet-tracking method made it into #STATMadness this year! doi.org/10.1038/s422... Vote for us! isbscience.us6.list-manage.com/track/click?... @isbscience.org @uwbioe.bsky.social @natmetabolism.nature.com @cdiener.com @medunigraz.at @chmoei.bsky.social @geeksthatspeak.bsky.social

🔎Details: CME Credits: 1 Monday, February 23 1 - 2 p.m. Eastern Registration: ow.ly/isKM50YhJx0 🧪

Dive deep into diet, gut microbes and metabolic health on The Proof Podcast with Simon Hill. You can watch the conversation on YouTube: youtu.be/Vops5BaKVlc?... If you want to see show notes and skip to specific parts- check it out on Spotify or Apple Podcasts.

WHO is soliciting the interest of internationally-renowned experts to serve on its Science Council, one of the Organization’s highest-level advisory bodies to the WHO Director-General @drtedros.who.int Know more: www.who.int/news/item/15...

Textbooks said neurons don’t burn fatty acids for energy🤔. Our study delivers the first in vivo demonstration that fatty acid oxidation in defined memory neurons fuels memory formation. Closing chapter of my PhD 🥳, out today in Nature Metabolism💥 @natmetabolism.nature.com

Top #Citations 2025: 9️⃣🧪 @cdiener.com @gibbological.bsky.social et al ( @isbscience.org @medunigraz.at#Citations) present a new method to estimate dietary intake from human stool by detecting food-derived DNA in faecal metagenomes.

Two scientists who are fast friends, one Nigerian and one American, have won the MacArthur Foundation's 100&Change competition for their network to catch the next disease with pandemic potential.

Amazing conference covering all things Women’s Health! I spoke about the midlife microbiome.

I’ll be starting a lab as an Assistant Professor at Cornell @cornellengineering.bsky.social in 2026! We’ll combine synthetic biology and materials science to engineer microbes into living materials & therapies. We're recruiting PhD students & postdocs - please get in touch! 🔗 harimotolab.com

🌟New PhD opportunity: 🌱🦠Predicting functional plant–microbiome networks for soil remediation 🌾🧫 The University of Manchester FSE Bicentenary PhD Competition funded (worldwide) Deadline 31st Jan, see info at bit.ly/4qn74qH @manchester.ac.uk @rothamsted.bsky.social @liverpooluni.bsky.social

Here are some of my thoughts on how to feed the gut microbiome 🧪 based on learnings from our research

I was able to share some of the learnings about diet choices for a happy and well-fed gut microbiome!🧪 Based on our work exploring how diet, the human host, and gut microbes interact to impact energy balance. gift link wapo.st/4ob7PBA Our work: lnkd.in/eBrAMTM7 lnkd.in/eaANWQvM

UC Davis is hiring! A tenure-track assistant professor of psychology, in human cognition or cognitive neuroscience #psychjobs recruit.ucdavis.edu/JPF07300

Duke Cell Biology is hiring in AI/ML! @scottsoderling.bsky.social, @rohitsingh8080.bsky.social, and others are building a very active community around ML for discovery science, and Duke is a great place to be. academicjobsonline.org/ajo/jobs/30509

Sept 25th marks a free 1-day symposium on "Understanding & Addressing Misinformation About Science," including opportunities for coordinated multi-sector action. In-person + virtual participation available: www.nationalacademies.org/event/45553_... 🧪 🌊 ⚒️ #geogsky

As one can imagine, I have some thoughts. Here’s a thread no one asked for: 1. SCIENCE IN THE US IS POLITICAL. No matter how much you want to ignore that fact, it is supported by taxpayer dollars and is therefore, political by nature. 2. BUT it has had bipartisan support for decades, which…

Sparking a child’s curiosity for science was the topic of this fun and personal conversation. 🧪 youtu.be/dVYGUbQVJmQ?...

While our official job ad is on the way, we are seeking PhD students to join @neuromadlab.bsky.social for projects running in Bonn. The candidate will lead projects on body-brain interactions using brain stimulation to improve core symptoms of depression: www.neuromadlab.org/jobs #neurojobs

You can get an accurate estimate of total bacterial biomass from stool metagenomes by simply normalizing by host read count, without needing any additional measurements. Excellent work by UW Master's student Gechlang Tang in @asm.org #mSystems Journal. journals.asm.org/doi/10.1128/... 🧵

Super excited to share our paper online 🚨today🚨 in Cell Host & Microbe‬! Xiaomei Ren @xiaomeiren.bsky.social and Mason Clark @rmasonclark.bsky.social‬ co-led discovery of ecological factors for Acinetobacter baumannii carriage in the gut, a reservoir for pathogen spread. 🎉 tinyurl.com/443kfefk

A study in Nature found that weight loss reduces cell senescence in people with obesity but doesn’t fully reverse all metabolic issues associated with obesity. go.nature.com/452Bbdv #medsky 🧪

DO NOT GIVE UP! Our advocacy is working. A key Senate committee has indicated that it will reject Trump’s proposed cuts to science agencies including NASA and the NSF. Keep speaking up and calling your electeds 🗣️🗣️🗣️

Such wisdom youtu.be/lW9c6t4potU?...

“Vaccines have done more to improve public health than any other medical intervention.” Cancer vaccines and the future of immunotherapy - www.thelancet.com/journals/lan... This exciting research gonna be a challenge for the antivaxx community...👆

The 1st Amendment protects scientists who engage in advocacy & activism - even if they work for a federal agency. We joined forces with @aclu.org to create a guide for scientists who wish to speak out while minimizing negative repercussions: www.csldf.org/resource/fir...

What a wonderful organization. I donated for their effort to go to DC to share their real life stories of how the big disgraceful bill will hurt families.

Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) in People With Diabetes: The Need for Screening and Early Intervention. A Consensus Report of the American Diabetes Association🔓 diabetesjournals.org/care/article...

The “Try This” podcast was all about gut health and featured our research 🧪 #geeksthatspeak podcasts.apple.com/us/podcast/t...

Out in final form today, our paper exploring whether microbiota encroachment into the mucosal lining is associated with MASLD in humans 🧪 journals.physiology.org/doi/full/10....

✊ACTION MENU✊ Science is under attack. But we’re fighting back. ✔️ Sign the Bethesda Declaration ✔️ Join our resistance to the Fool’s Gold EO ✔️ Take action in your community ✊ Let’s flood the zone with science.

A US judge has ordered hundreds of terminated research projects at the US National Institutes of Health to be reinstated, calling the processes that led to their cancellation “bereft of reasoning”. https://go.nature.com/4kOmXDy

It’s #NoKings day in Seattle. I’m ready. Solidarity, to fellow citizens across the U.S. and to freedom-loving compatriots around the world. Stand with us! Stand up for democracy, science, journalism, freedom of speech, peace, justice, rule of law, and a diverse and open society. 🕊️✊ 🚫👑

We’re honored to report that over 11 million showed up for today’s No Kings protest, and totals are still coming in. Just… wow. WOW 😮! There’s nothing more to say.

Update: Over 7.2 million and counting across the country for the No Kings protest!!

Y’all mind if I lib out a little bit? No Kings Tallahassee!

No Kings. Place De la Bastille Paris

Well said by the American Academy of Pediatrics.

Trump's military parade will cost $25-45 Million dollars, while federal funding for science is slashed, public servants are fired, and life-saving programs are ended, presumably to save money. Got it. I'll be saying what I think about that at @indivisible.org #NoKingsDay tomorrow. #StandUpForScience

Happy No Kings Day! Our friends around the world are already getting started. See y'all out there today!

Yes! I heard some people haven’t signed because they aren’t a scientist or academic. But this is about all of us. If you are against harming research participants, sign! If you want more life-saving treatments, sign! If you value free speech, sign!

Land of the free.

Delaware getting loud - fuck ICE, fuck trump - the country belongs to the people #nokings

If you have ever wondered what might happen to short chain fatty acids made by the microbiome. Here is a large class of metabolites and how they link to biology. www.cell.com/cell/fulltex...

The liver can’t be ignored in the care of people with diabetes. 🧪 Humbled to have contributed to this consensus statement from the American Diabetes Association. It’s a comprehensive resource outlining early detection, treatment, and team-based care. diabetesjournals.org/care/article...

𝗡𝘂𝘁𝗿𝗶𝘁𝗶𝗼𝗻 𝗶𝗻 𝗠𝗲𝗱𝗶𝗰𝗶𝗻𝗲: 𝗠𝗮𝗹𝗻𝘂𝘁𝗿𝗶𝘁𝗶𝗼𝗻 𝗶𝗻 𝗔𝗴𝗶𝗻𝗴 Malnutrition in older adults is common, underrecognized, and contributes to poor health and risk of death. Guidelines are available to facilitate prevention and treatment of malnutrition. Learn more: nej.md/43OlrLP @fau.de #MedSky

As therapies emerge, broad adoption of screening for liver fibrosis as a new standard of care hold promise for a future without cirrhosis for people with prediabetes and type 2 #diabetes #MASLD #MASH diabetesjournals.org/care/article...

It’s so easy to comment. I did! Making institute directors political appointees will destroy the ability to do unbiased science. It will destroy the scientific integrity of federal grants. 🧪