There's new work from the lab of Dr. Patrick Stayton at @uwbioe.bsky.social! 👇 It shows that an alveolar macrophage-targeted polymeric #prodrug serves as a reservoir for releasing #antibiotics to treat infections caused by a primarily extracellular bacterium. 🗒️: https://bit.ly/49lJWS1

New year, new experiments… and maybe some new habits too! Kick off 2026 with Lab Coats and Life, the podcast that helps scientists navigate the human side of research. If your resolutions include more balance, purpose, and curiosity, this is the perfect place to start. 🎧 https://bit.ly/4pTHNnx

Happy New Year! 🎉 May your 2026 be statistically significant, your experiments run smoothly, and your p-values forever low. Here’s to better data, brighter ideas, and brilliant minds working together across Seattle!

The #1 spot in our Top 5 Countdown is... 🥁 Dr. Meghan Koch at @fredhutch.org, who uncovered a biological mechanism behind the gut's immune system! Congratulations and we cannot wait to see what discoveries await in 2026. https://bsky.app/profile/scienceinseattle.com/post/3m25u57xxk62x

At #2, we honor two leaders in biomedical research. Dr. Karel Svoboda and Dr. Jay Shendure (@jshendure.bsky.social) were elected to the National Academy of Medicine this year! A well-deserved recognition of visionary work. https://bsky.app/profile/scienceinseattle.com/post/3m3xapuxncp2y

🥉 Taking the #3 spot in our 2025 Post Countdown is the @isbscience.org Virtual Microbiome Symposium! Don't worry if you missed out, the full recap is online: https://bit.ly/4qeNDQ4 https://bsky.app/profile/scienceinseattle.com/post/3m5wob373ce2k

Our #4 story of the year maps the developing brain across species. This year, @alleninstitute.org researchers helped create the BRAIN Initiative Cell Atlas Network, a remarkable series of publications in Nature. 🤯 https://bsky.app/profile/scienceinseattle.com/post/3m5cxgqdfse2f

We're starting off our Top 5 Post Countdown with a new path for treating schizophrenia. WRF awarded a $275,000 commercialization grant to Dr. Nino Ramirez at @seattlechildrens.org to develop a therapy that could halt the disease. https://bsky.app/profile/scienceinseattle.com/post/3lwhlmuakyc23

Ready for the science highlight reel of the year? 🤓 🧪 Welcome to the Science in Seattle Top 5 Post Countdown, showcasing the most community-loved posts of 2025. Get ready for jaw-dropping discoveries and the people who made it all possible! Check back tomorrow for #5...

❄️☃️ Looking for something insightful to listen to over the holidays? Explore the @immunologypodcast.com! Whether you're traveling or unwinding at home, it’s the ideal companion for curious minds. 🎧 https://bit.ly/47nGZAG

🎧 As the year winds down, it’s the perfect time to recharge your curiosity. Explore the @stemcellpodcast.com, where experts share insights on stem cell biology, new technologies, and the future of regenerative medicine. 🎄 Add it to your holiday playlist: https://bit.ly/4pJa6VA

Our website is taking a short holiday break while we recharge for 2026. But don’t worry, the science doesn’t stop! Keep an eye on our socials over the holidays for community highlights, Top 5 countdowns, and plenty of good science stories to carry you into the new year. See you in January! ❄️🔬

The Nobel Assembly at Karolinska Institutet has awarded the 2025 Nobel Prize in Physiology or Medicine to Drs. Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi in a ceremony on December 11! 👏 Let's give another round of applause for our Seattle researchers: https://bit.ly/48MHHYY

Dr. Peter Linsley from the @benaroyaresearch.bsky.social has been honored with the Puget Sound Business Journal’s 2025 Lifetime Achievement Award. 🏅 Dr. Linsley has spent nearly three decades advancing biotechnology and pharmaceutical research. Congratulations! https://bit.ly/4p4hTfD

If you missed the 2025 @isbscience.org Virtual Microbiome Symposium (theme: how microbial metabolites influence the brain, the immune system, & metabolism), the videos of the talks and the panel discussion are now available here: youtube.com/playlist?lis... Thanks to all who helped make it happen!

💡Dr. Elizabeth Wayne is using the enzyme that gives fireflies their glow to study the white blood cells that attack cancer in the human body. With her team at @uwbioe.bsky.social, she has invented a new way of using bioluminescence to track the development of #macrophages: https://bit.ly/3L5R2Sm

A recent study from Drs. Alexandra Willcox and Julie Overbaugh at @fredhutch.org reveals when the #Zika virus invades, interferon musters the usual militia, but the alarm is regulated by a gene with a previously unknown antiviral function! 📰 https://bit.ly/48UjJJY 🧪 https://bit.ly/4gEa65P

Dr. Nora Disis from @uwbiology.bsky.social was honored with the Seahawks’ Delta Community Captain award for her groundbreaking work developing cancer vaccines that harness the body's immune system to fight disease. 🪶 Congratulations Dr. Disis! https://bit.ly/3MzX9ip

Dr. Min (Mia) Yang at @uwiscrm.bsky.social has received an NIH Director’s ­New Innovator Award that will enable her lab to recreate key aspects of early embryonic development. 🎇 Congratulations! https://bit.ly/44Jvzpd

🏅 Elana Thieme and Mark Mendoza from @fredhutch.org were the recipients of the @ash.hematology.org Graduate Awards! The two-year, $40,000 annual awards support emerging researchers studying myelodysplastic syndromes and pediatric #leukemia: https://bit.ly/3MwN2uM

Dr. Paul Yager at @uwmnewsroom.bsky.social developed inexpensive, paper-based tests that will allow individuals to frequently monitor multiple #biomarkers in blood or other biofluids in their homes. Dr. Yager is now pushing his innovation forward into a new startup, UbiDX: https://bit.ly/4oIu6q3

#StemCell and #DevBio communities, mark your calendars for Sept. 23-25! Together with @isscr.org and @socdevbio.bsky.social#StemCell#DevBiowe're presenting a scientific symposium led by the next generation. Researchers at all stages are invited to be a part of this collaborative event 🔗 https://bit.ly/4rO7xTy

Two new studies published in Nature bring the world closer to potential long-term treatments for #HIV. The studies bring together formidable teams of more than 40 scientists, including Dr. Lillian Cohn at @fredhutch.org#HIV: https://bit.ly/4q2mu2U

📢 Check out this new study from the lab of Dr. Alison Paquette (@alisonpaquette.bsky.social) at Seattle Children’s Research Institute! It shows that the placental transcriptome serves as a mechanistic link between prenatal #phthalate exposure and #placental efficiency. 🔗 https://bit.ly/4rFwgcV

📣 @uwproteindesign.bsky.social is releasing RFdiffusion3 as #OpenSource software. This state-of-the-art AI model for #biodesign is capable of generating new proteins that interact with any type of molecule commonly found inside living cells. 🤓 Learn more: https://bit.ly/4iDokVn

From $100 a gram to 10 cents, #antibody production is having a revolution! Seattle-based @lumenbio.bsky.social#antibody, led by CEO Brian Finrow, is developing a method to produce antibodies in edible spirulina, drastically lowering costs and enabling oral administration: https://bit.ly/4oyZqYe

Teach neuroscience to undergrads? Learn how to incorporate our connectomics data into your courses! 🗓️ July 23-24 🛫 Travel funds available ⏳ Apply by Feb. 2. https://alleninstitute.org/events/incorporating-open-connectomics-data-into-teaching-neuroscience/

Fred Hutch at #ASH25: Catch our latest findings in blood cancer treatments, efforts to improve access to innovative new therapies and the biological underpinnings of disease. 🩸👇 https://bit.ly/4iRN2BH

🧐 University of Washington's Shubham Bansal, a senior undergrad in neuroscience, has been named a 2026 Rhodes Scholar, one of the most prestigious academic awards for U.S. students. He is UW's 38th Rhodes Scholar. Congratulations! https://bit.ly/48M494c

Hear, hear!

Great article from @UWBiostats on the SCORCHER Project and its effort to make AI and statistical tools easier for cancer researchers. Led by PI @jtleek.bsky.social and co-PI Steve Salerno, the project is doing important work to open up these methods. www.biostat.washington.edu/news/stories...

A new study published in Scientific Reports shows that #eDNA can move between air and water, which was a possibility scientists hadn’t accounted for before! Learn more about this breakthrough sampling method from Aden Yincheong Ip & Dr. Ryan Kelly at @uwbiology.bsky.social#eDNA: https://bit.ly/4omc10N

Dr. William Altemeier from @uwmedicine.bsky.social has been recently appointed as the Endowed Chair in Pulmonary Disease Research. He is a specialist in transcriptional regulation during #AcuteLungInjury. 🤩 Congratulations Dr. Altemeier! https://bit.ly/3Kgv5jf

The @uofwa.bsky.social is proud to announce that 56 faculty and researchers who completed their work while at UW have been named on the Highly Cited Researchers 2025 list from Clarivate.

In a recent study published in @cp-cellrepmed.bsky.social , members of the Gujral Lab at @fredhutch.org performed a drug screen to find drugs that could target the tumor microenvironment. One that stood out? Doramapimod! 📰: https://bit.ly/48dzI5y 📝: https://bit.ly/4p2Onb3

Treat yourself to an extra helping of science with #LabNotes! It's perfect for: 🚗🚙 Thanksgiving travel 🧑‍🍳🍗 food prep 🗣️❌ giving you a break from that one relative (you know the one) Listen in: https://alleninstitute.org/podcast-lab-notes/ #Thanksgiving #Thanksgiving2025

🩸Dr. Matthias Stephan at @fredhutch.org is developing a special foam to try to make gene therapy for blood stem cell defects an easy, bedside procedure. “We can use our foam to genetically modify #BoneMarrowStemCells at a very high efficiency,” said Dr. Stephan: https://bit.ly/48gOMiV

We are hiring! We have a postdoc position opened @fredhutch.org to join our team to design next gen cellular therapies for cancer. Heavy focus on T cell signaling and understanding how synthetic receptors instruct T cells to fight cancer.

Congratulations the @uwmedicine.bsky.social scientists selected as Highly Cited Researchers from the Web of Science Group! 👏 🥂 Cheers to Drs. William Banks, Helen Chu, David Maloney, Ganesh Raghu, Stanley Riddell, and Katherine Tuttle: https://bit.ly/482ChbS

🤯 Seattle’s @parse.bsky.social is teed up for an acquisition by Qiagen, a Netherlands-based holding company, in a $225 million cash deal. Parse was co-founded in 2018 by @uwproteindesign.bsky.social 's Drs. Alex Rosenberg and Charles Roco: https://bit.ly/48i2pyi

Congrats to Fred Hutch's Katrina Ortblad and @jsb-ucla.bsky.social on recently being awarded #R01 grants from the NIH! The grants will support Ortblad's work optimizing HIV prevention care and Li's development of a computational tool for reliable single-cell omics analysis. https://bit.ly/3XNNbMw

Harnessing the muscle of one of the world’s fastest supercomputers, researchers at the @alleninstitute.org and their collaborators have built one of the largest and most detailed biophysically realistic brain simulations of an animal ever! 🐁 See the #MouseBrain simulation: https://bit.ly/47TFf2e

🥰 A huge thank you to everyone who came out to make new connections and share ideas at our Seattle Life Sciences Networking Night earlier this month. And a very special thank you to our two speakers for the night: Dr. Emma Kuan and Sam Nutt. We can’t wait to see you next time! #SeattleScience

New @JAMAOnc study links ultraprocessed foods to colorectal polyps in under-50s. But classifying foods was tricky, notes Fred Hutch's Dr. Marian Neuhouser, making results less certain. Still, findings echo recent research. Read more: https://nyti.ms/3M1ZfXL

OTC gene variants cause ornithine transcarbamylase deficiency, a rare X-chromosome-linked disorder that affects the body’s ability to clear ammonia. Dr. Aimée Dudley's lab at the Pacific Northwest Research Institute isolated the genetic impact of each OTC variant using yeast: https://bit.ly/4ieTwKA

🦠 The @isbscience.org Virtual Microbiome Symposium is on December 12, 2025! This virtual symposium will dive into the influence of gut microbial metabolites on human #physiology. This event is perfect for everyone in academia, industry, and the clinic. Register now: https://bit.ly/4oe67iw

A new $5.2 million grant from WRF will help develop a new clinical trials program between @fredhutch.org & @seattlechildrens.org . The program, led by Dr. Folashade “Shade” Otegbeye, will focus on first-in-human clinical studies of brand-new therapeutics for rare cancers: https://bit.ly/3X2lteO

TOMORROW at #SfN25 - learn how multi-omics approaches are revealing how evolution acts on cell types, underpinning neural circuitry and behavior changes across diverse species. 📅 Tues., 11/18, 9:30am–12:00pm 📍 Rm 6CF 📲 https://www.abstractsonline.com/pp8/#!/21171/session/1213

🔬 Curious minds unite! Come down to Seattle Public Library SW Branch for the “Sunday Science Party” this Sunday from 2-3 PM. This free, all-ages, hands-on event will help you and your family explore questions with local UW scientists: https://bit.ly/4oA7bOs

Dr. Paul Thomas @pgtimmune.bsky.social is working to turn the “incredible potential” of the immune system into real-life diagnostic and therapeutic applications that will improve vaccination strategies and #CancerTreatments. Check out his work at @fredhutch.org#CancerTreatments: https://bit.ly/4p3kmr0