Join us for a special @varianteffect.bsky.social Fireside Chat on Jan 6th, 2026 (9-10am Pacific) w/ @maitreya.bsky.social (@uwgenome.bsky.social) & @mehurles.bsky.social (@sangerinstitute.bsky.social) Visit www.varianteffect.org/event/firesi... for more info and to add this event to your calendar

Coming up! Rewriting Cancer’s Script: Insights from Saturation Genome Editing 🗓️ 25 November 2025 4 PM CET | 7 AM PST @twistbioscience.com #Webinar with @davidjadams.bsky.social @sangerinstitute.bsky.social Register for this free webinar here: tinyurl.com/RewritingCan...

If you are planning to attend the Mutational Scanning Symposium next year in Melbourne, we recommend that you register as soon as possible to secure your spot! 🗓️ March 25-27, 2026 ➡️ Register now 📝 Submit your abstract 🇦🇺 Apply for your Visa 🛫 Book your flight ℹ️ ➡️ www.mss2026.org #VariantEffect26

🎙️ Next up Dec 2 in VESS! Thea Schulze (Lindorff-Larsen Lab): Predicting mutated protein abundance @tkschulze.bsky.social Taylor Mighell (Lehner Lab): Massive mutagenesis to understand GPCRs @taylor-mighell.bsky.social 🔗 More info at varianteffect.org/seminar-series @varianteffect.bsky.social

2026 Mutational Scanning Symposium & Workshop will be here before you know it! Register now to secure your spot and get a ticket 🎟️ for the conference dinner at Melbourne Museum! 🦕 tinyurl.com/MSS26Registr... #VariantEffect26 #Dinosaurs #RegisterNow

🗓️Abstract Deadline Extended to December 1st, 2025! #VariantEffect26 ℹ️https://www.mss2026.org

Coming up next week! Free! No registration required! ℹ️ www.varianteffect.org/seminar-seri...

We have an incredible speaker line-up for next years Mutational Scanning Symposium 🤩. Register now and submit your abstract before the deadline next week! ℹ️ www.mss2026.org #VariantEffect26 #FOMO #Functional #Genomics #Symposium #Abstract #Deadline

brotmanbaty.org/news/q-and-a... @brotmanbaty.bsky.social Q&A with #VariantEffect26 co-organizer Rehan Villani.

Join us for the 9th Annual Mutational Scanning Symposium! #VariantEffect26 When: March 25-27, 2026 Where: Melbourne, Australia (and online!) Be sure to submit your abstract by Nov 2nd 2025 ℹ️https://www.mss2026.org

We are #Hiring! Note the close date of tomorrow October 14th!

📣 We are #Hiring 🌟 Scientific Communications Manager -Part Time 🔹 Communications role for our Global Alliance! 🔹 Hinxton, Cambridgeshire UK and hybrid 🔹 Part-time 🔹 Closing on Oct. 14th (TOMORROW!) ➡️https://tinyurl.com/CommunicationsJob @sangerinstitute.bsky.social #ScienceJobs #Communications

Be sure to check out our monthly Seminar Series! 🔹Upcoming speakers www.varianteffect.org/seminar-seri... 🔹Previous speakers www.varianteffect.org/previous-sem... #Seminar #Series #Science #FunctionalGenomics

🎥 My Variant Effects Seminar Series (VESS) talk is now on YouTube! I discuss how DropSynth-based gene synthesis reveals how bacterial DHFR variants evolve antibiotic resistance. Thanks to @varianteffect.bsky.social for the invite! 🔗 www.youtube.com/watch?v=KiA9... #VESS #VariantEffects #DropSynth

Coming up next in the VESS (Nov 4): Population genetics × variant effects: 🧬 Nikhil Milind (Stanford) on gene dosage and complex traits @nikhilmilind.dev 🧬 Leslie Smith (U Florida) on equitable ML in cancer genomics www.varianteffect.org/seminar-seri... @varianteffect.bsky.social

🌏 🧬 Join the global functional genomics community in Melbourne this March for MSS26! The 9th Annual Mutational Scanning Symposium #VariantEffect26 runs March 25–27, 2026 at the Aikenhead Centre for Medical Discovery. 🗓️ Early bird registration & abstract submissions close Nov 2, 2025. www.mss2026.org

🌟 Scientific Communications Manager -Part Time 📣 We are #Hiring 🔹 Communications role for our Global Alliance! 🔹 Hinxton, Cambridgeshire UK and hybrid 🔹 Part-time 🔹 Closing on Oct. 14th Learn more and apply! @sangerinstitute.bsky.social www.linkedin.com/posts/atlas-...

🌏 🧬 Join the global functional genomics community in Melbourne this March for MSS26! The 9th Annual Mutational Scanning Symposium #VariantEffect26 runs March 25–27, 2026 at the Aikenhead Centre for Medical Discovery. Abstract submissions are open and will close 2 November 2025. www.mss2026.org

Variant Effects Seminar Series October and November lineup! Join us! ℹ️https://www.varianteffect.org/seminar-series/

This role, based at Sanger, will lead on the communications for the Atlas of Variant Effects Alliance - an initiative that is mapping the effects of all the possible variants of human genes 🧬 This is a part-time role, closing on 14th Oct. More info ⤵️ sanger.wd103.myworkdayjobs.com/WellcomeSang...

I'm stoked to be organising next year's MSS right here in beautiful Melbourne! We know Australia is very far away, and we're working hard to make sure we can support as many ECRs to attend as possible, so please do register and apply for a travel award!

We are #Hiring! Communications role for our Global Alliance! 🌍🧬 Please share this post with your network, or apply if you are interested! 📍 Location: Hinxton, England 🕒 Part-time role ℹ️ sanger.wd103.myworkdayjobs.com/en-US/Wellco... #ScienceJobs #Communications #Genomics #PartTimeRole #UKJobs

We are hiring! Communications role for our Global Alliance! sanger.wd103.myworkdayjobs.com/en-US/Wellco... #job #hiring #Communications Hinxton, Cambridgeshire UK

📣Call for Abstracts for the Mutational Scanning Symposium! #VariantEffect26 🗓️ March 25-27, 2026 📍 Melbourne, Australia (and online!) 📝 Submit your abstract (deadline is Nov 2nd, 2025!) ➡️ Registration is also now open!! ℹ️ www.mss2026.org #FunctionalGenomics #Symposium #Australia #CallForAbstracts

🧬 Out this month in Nature Reviews Cardiology: A powerful look at how multiplexed assays of variant effects (MAVEs) are reshaping our understanding of cardiovascular disease genetics. Contributors include members of the AVE Alliance. 📑 www.nature.com/articles/s41... #Cardiology #FunctionalGenomics

mutational scanning is awesome

This is one not to miss! We look forward to seeing you all in Melbourne. #VariantEffect26 ⏰Abstract deadline is Nov 2nd 2025.

Registration is now open for the Mutational Scanning Symposium!! This is one not to miss. Invited speakers include @mehurles.bsky.social @sangerinstitute.bsky.social @maitreya.bsky.social @uwgenome.bsky.social #VariantEffect26 Register soon for the early bird rate! ℹ️➡️https://www.mss2026.org

MSS is a cornerstone event for the functional genomics community. Did you know that the Mutational Scanning Symposium has been held eight times since 2017? We have an amazing community! Join us next year in Australia! www.mss2026.org (Registration to open soon). #VariantEffect26

📢 Empower Genomic Innovation with Your Sponsorship! 🧬 We are looking for generous #sponsors to support the upcoming Mutational Scanning Symposium. #VariantEffect26 ℹ️ www.mss2026.org For sponsorship inquiries, please contact 📩 [email protected]

The 9th Annual Mutational Scanning Symposium will be held in Melbourne, Australia March 25-27, 2026 🌟 #VariantEffect26 www.mss2026.org Registration will open soon!!!!

Next up! Two applications of MAVE! 🧬 DNA damage repair & cancer: Shelby Hemker (@jacobkitzman.bsky.social lab UMich) measures DNA repair of MUTYH variants. 🦠Antibiotic resistance: @kroman.bsky.social (‪@synplexity.bsky.social Univ. of Oregon) decodes how mutations drive resistance in DHFR.

Variant Effects Seminar is today! (9am Pacific) www.varianteffect.org/seminar-seri...

Looking forward to the Variant Effects Seminar tomorrow! @michaelherger.bsky.social and I will present our pooled prime editing platform for high-throughput variant screening.

Critical Assessment of Genome Interpretation (CAGI) challenges are live! 🧬💻 genomeinterpretation.org/cagi7-challe... A total of 12 challenges have launched Including #DeepMutationalScanning Challenges ⏰ Deadlines approaching! #CAGI #GenomeInterpretation #VariantEffect

Interested in viewing a talk from a previous Mutational Scanning Symposium? Visit our youtube channel. 📺 🍿 www.youtube.com/@cmap_cegs84... @isabellease.bsky.social 's wonderful #VariantEffect25 illustrations can be found here. 🎨 isabellezane.bio

Coming up! ℹ️ www.varianteffect.org/seminar-seri...

Why yes! You can watch previous Variant Effects Seminar Series talks on our YouTube channel! ℹ️ www.varianteffect.org/previous-sem... 📺 www.youtube.com/playlist?lis... #Genomics #Seminar #EarlyCareerResearchers #ScientificSeminar #PrecisionMedicine

Apply for Multiplex Assays of Variant Effects training by 18 August! ⏰ Join our experts to learn how to strengthen your genetic disease research or clinical work using MAVE data. 🧬 Financial assistance available💸 📎Find out more: bit.ly/3EW3lh4 #MAVE25 #VariantInterpretation

⏰The application deadline is Monday Aug 18❗ @eventswcs.bsky.social ℹ️https://coursesandconferences.wellcomeconnectingscience.org/event/multiplex-assays-of-variant-effects-maves-approaches-analysis-and-interpretation-20251123/

Coming up in September! ➡️Christina Kajba @ckajba.bsky.social & Michael Herger @michaelherger.bsky.social — pooled prime editing screens in haploid human cells ➡️Jon Acosta — multiplexed in vivo base editing screens #GeneticVariants #PrimeEditing ℹ️https://www.varianteffect.org/seminar-series/

Ever wondered how your genes shape your health? Dive into the Variants and Us (VUS) Podcast—where cutting-edge science meets real-world impact. 🎧 varianteffect.org/podcast/ #Genetics #RareDisease #VariantEffect #SciencePodcast #PersonalizedMedicine

‪🗓️ Join us tomorrow! August 5 with @nurdankuru.bsky.social (CSHL) @cshlnews.bsky.social and Ferdy van Geest (ErasmusMC) #Genetics #RareDisease #MedicalGenetics ℹ️ www.varianteffect.org/seminar-seri...

🧬 Interested in variant interpretation? #FunctionalGenomics #Pharmacogenetics #MutationalScanning #VariantEffectPredictor #RareDisease #Collaboration #PrecisionMedicine Check out our list of publications! 📖 www.varianteffect.org/publications/

Interested in using functional data to understand clinical variants? Been hunting for a good review of the topic? We just wrote one! rdcu.be/exaEU

Coming up on August 5 🗓️ Nurdan Kuru @nurdankuru.bsky.social shares phylogeny-aware methods for variant effect prediction. Ferdy van Geest dives into MCT8 variants & thyroid disease. Computational meets clinical! #Genetics #RareDisease #MedicalGenetics ℹ️ www.varianteffect.org/seminar-seri...

More information and to listen visit>> www.varianteffect.org/podcast/

🎧 New Episode! 🧬 "Biocuration: From Evidence to Classification" Interviews w/ @heidirehm.bsky.social @broadinstitute.org & Courtney Thaxton #ClinGen #Genomics #Biocuration #SciencePodcast #PrecisionMedicine

Happening tomorrow (July 1st) Hope you can join us! www.varianteffect.org/seminar-seri...

We are pleased to announce the publication of our manuscript "Mapping MAVE data for use in human genomics applications" in Genome Biology! 🧵 1/3 genomebiology.biomedcentral.com/articles/10....