Writing in @nature.com Nature Biotechnology, YSM #researchers introduce Perturb-DBiT, a novel method for spatially resolved #CRISPR screening in complex tissue environments. medicine.yale.edu/publication-...

A new YSM study develops a precise and efficient method for synthesizing engineered circular RNAs (circRNAs), which hold significant potential for advancing RNA-based therapeutics for conditions including infectious #diseases and #cancer. Learn more: medicine.yale.edu/publication-...

In a recent study, YSM researchers investigate how PI3K enables #pancreatic #cancer cells to resist KRAS inhibitors by activating wild-type RAS signaling, suggesting combined PI3K-KRAS targeting as a #therapeutic strategy. Learn more: medicine.yale.edu/publication-...

A new YSM-led study shows how dietary #fat composition shapes #pancreatic #cancer risk. The results are published in Cancer Discovery: medicine.yale.edu/publication-...

Writing in @nature.com Nature Genetics, YSM researchers introduce a #DeepLearning #AI tool that can combine and interpret spatial transcriptomics (ST) data from multiple streams. The tool, INSPIRE, could offer more detailed mapping of tissues: medicine.yale.edu/publication-...

A YSM study led by Carlos Oliveira, MD, PhD, finds #nirsevimab is effective at preventing severe #RSV disease in infants – but timing matters, since the drug's effectiveness declines over the three months after injection. @jama.com medicine.yale.edu/news-arti...

Cancer-causing mutations in tissue aren’t uncommon. Many, though, never turn into cancer. Why? New research of mouse stem cells may help us understand how cancer grabs a foothold: brnw.ch/21wQkRK #cancer #stemcell #cancermutation

In a new study published in Nature #Cancer, YSM researchers find ORACLE, a new genetic test performed on #tumors, can better predict patient survival with #lungcancer – even at the earliest stages of disease. @nature.com brnw.ch/21wQ24B

On The Oprah Podcast this week, Ania Jastreboff, MD, PhD, of the Yale Department of Internal Medicine, discusses GLP-1 #weightloss #drugs, how they work in the brain, and the new revolution in #obesity treatment. @oprah-winfrey.bsky.social www.youtube.com/watch?v=_GEe...

Could an #eyetest assess risk of #psychosis? A new Yale Department of Psychiatry study linking #paranoia and teleological thinking to visual perception suggests it might. news.yale.edu/2024/12/17/p...

For older adults with multiple #prescriptions to manage, some #drug interactions may do more harm than good. An international team led by YSM's Terri Fried, MD, has introduced guidelines to help doctors and health systems start conversations about #deprescribing: medicine.yale.edu/news-article...

In a recent study, YSM researchers in the lab of Carolyn Fredericks, PhD, explore how structural differences between men's and #women's #brains may impact the risk for #Alzheimers disease – and inform future treatments. medicine.yale.edu/news-article...

YSM researchers have developed a cost-effective new #test to search for #mutations that cause dystroglycanopathies, a group of rare and life-threatening #genetic disorders: medicine.yale.edu/news-article...

How are sweet flavors and influencer marketing impacting trends in youth #vaping? Researchers in the Yale Department of Psychiatry say #tobacco companies use a variety of techniques to successfully target kids and teens on #socialmedia: medicine.yale.edu/news-article...

A growing number of #employers are offering workers #menopause related benefits in their #health #insurance plans. Menopause care is “an important place for companies to step in,” says YSM's Hugh Taylor, MD, in an interview with @washingtonpost.com this week: www.washingtonpost.com/health/2024/...