💬 Viewpoint: Homelessness is shaped by federal policies, and addressing it requires evidence-based solutions centered on affordable housing and community support rather than prioritizing public safety measures. ja.ma/4gwFbbs

Manufacturers of >90% of FDA-listed #AI- and machine learning–enabled devices publicly disclosed no payments to clinicians or teaching hospitals from 2017-2023, but the $ amount of general payments doubled in that time frame. ja.ma/3VVS9WB

Among patients receiving inpatient rehabilitation for acute stroke, levodopa added to standardized rehabilitation did not significantly improve motor function at 3 months compared with placebo plus standardized rehabilitation. ja.ma/46nsXNv

Apply to the 2026-2027 Morris Fishbein Fellowship in Medical Editing for the chance to develop your skills in all facets of editing and publishing a major medical journal. This is an in-person position located in Chicago. Applicants must hold an MD or DO degree to be eligible. ja.ma/4pvWYUm

💬 Viewpoint: Terminating grants related to #HIV prevention jeopardizes decades of progress and risks increased morbidity and mortality from preventable new HIV infections. ja.ma/4mptTqA

#Hypothyroidism is a condition characterized by the insufficient production of thyroid hormones. This Review summarizes the epidemiology, pathophysiology, clinical presentation, and treatment of primary overt hypothyroidism in nonpregnant adults. ja.ma/47mJ4gB

In patients without atrial arrhythmia recurrence after AF ablation, discontinuing oral anticoagulant therapy reduced the composite risk of stroke, systemic embolism, and major bleeding compared with continued therapy. ja.ma/4ptyye9

Centralizing data from diverse reporting systems enables timely, actionable measles surveillance, helping guide public health interventions, improve vaccination efforts, and model outbreak risk more precisely within communities. ja.ma/3IwmxUl

#GLP1 medicines now address weight loss and other health conditions through innovative formulations and expanded indications, highlighting key questions about their efficacy and safety. ja.ma/46NzCly

Type 2 diabetes affects up to 14% of the global population and is associated with preventable long-term complications. This Review discusses the diagnosis, treatment, and prognosis of adults with type 2 diabetes. ja.ma/4nFTxZ9

Ultraprocessed foods make up much of the US diet. And @americanheart.bsky.social says the cardiometabolic harms may extend past their caloric and nutritional content. ja.ma/47N3AHp

Prostatitis is defined as infection, inflammation, or pain of the prostate gland and affects approximately 9.3% of men in their lifetime. This Review summarizes current evidence on the evaluation and management of prostatitis. ja.ma/4prpNB3

In the latest episode of the JAMA Medical News podcast, Felix Mahfoud, MD, chair of the Department of Cardiology at University Hospital Basel, shares clinical research highlights from the recent European Society of Cardiology Congress: Listen now: ja.ma/42zYevz

Superficial vein thrombosis (SuVT) is characterized by thrombus in the superficial veins, typically in the lower or upper extremities. This Review summarizes the diagnosis and treatment of SuVT. ja.ma/4gtRzc6

Editorial: "Remembering Drummond Rennie—Champion of Integrity in Science and Scientific Publication." ja.ma/3KvjOuX

🎙️ In the latest episode of JAMA Editor's Summary, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Deputy Editor Preeti Malani, MD, MSJ, discuss the latest science published in JAMA. Listen now: ja.ma/4gxOWpP

Editorial: "Remembering Drummond Rennie—Champion of Integrity in Science and Scientific Publication." ja.ma/422578O

The Morris Fishbein Fellowship in Medical Editing is a unique one-year fellowship offered by JAMA to introduce physicians to all facets of editing and publishing a major medical journal at our headquarters in Chicago. 📅 Apply by Jan. 5, 2026. ja.ma/4naYkCm

“The Enigma of Protein Domains of Low-Sequence Complexity” #LaskerAward winner Steven McKnight writes about his interest in “these ugly duckling proteins” that turned out to be critical for cellular function. #RNAbiology #phaseseparation #Lasker2025 @jama.com jamanetwork.com/journals/jam...

“My life in science has been a gift that has allowed me to explore the chemical logic of a living cell while also remaining keenly aware of the state of global health.”—#LaskerAward winner Lucy Shapiro reflects on her career 🧪 #devbio #systemsbiology @JAMA.com

Menopausal hormone therapy was seen as a cure-all before new trial results branded it dangerous in the early 2000s. A new analysis of Women’s Health Initiative trial data offers clarity on hormone therapy for vasomotor symptoms in different ages. #MedSky

What you need to know about this year’s #ESCCongress: from the latest on #GLP1 drugs and β-blockers to the potential #cardiovascular benefits of the #shingles vaccine and the risks of poor mental health. #MedSky #CardioSky

📌 Editor’s Choice from this week's issue of #JAMA: ➡️ Stapokibart for Chronic Rhinosinusitis ➡️ Reducing Barriers to Mental Health Care for Physicians ➡️ Toripalimab Combination Therapy w/o Concurrent Cisplatin for Nasopharyngeal Carcinoma; and more. ja.ma/4eRp9GH

Editorial: Extreme weather events are common in the US and are becoming more frequent, severe, and expensive. Three articles on wildfires emphasize the importance of planning, surveillance, and response. ja.ma/4mlZ9a0

The 2023 Maui wildfires were linked to an increase in suicide and overdose deaths, with a 97% increase in Maui and a broader 46% rise across all Hawaiian Islands. ja.ma/46uvZ2L

An estimated 440 excess deaths were attributed to the January 2025 wildfires in Los Angeles County, underscoring indirect health effects and the need for improved mortality tracking. ja.ma/4gtC9Vc

In this episode of JAMA+ AI Conversations, JAMA+ AI EIC Roy Perlis, MD, MSc, speaks with Michael Howell, MD, MPH, chief clinical officer at Google, about how he aims to balance innovation and safety in #AI-driven medicine. Listen now: ja.ma/41XXWhT

💬 Viewpoint: The evolving health care landscape necessitates a new clinician-scholar paradigm incorporating humanities and social sciences to address complex challenges and enhance scientific inquiry and health outcomes. ja.ma/4puvyhl

"JAMA pulled back the curtain on high-impact publishing in a way that few experiences could." In this Editorial, JAMA editorial fellows share insights from their yearlong experience observing the journal's editorial process. ja.ma/4pqLQYy

Endometriosis is a chronic inflammatory disease in which cells similar to those lining the uterus are present outside of the uterus. This JAMA Patient Page describes endometriosis development, as well as its signs and symptoms, diagnosis, and treatment. ja.ma/3K53fpL

In his own words—#LaskerAward winner Dirk Görlich explains the scientific thinking behind discovering the critical functions of low-complexity domains within protein sequences. 🧪 #Lasker2025 #phaseseparation @JAMA.com @mpi-nat.bsky.social jamanetwork.com/journals/jam...

Viewpoint: Transgender and gender-diverse individuals face barriers to equitable #cancer care due to their underrepresentation in #oncology research and inadequate inclusion in cancer registries. ja.ma/3KbFmN4

📊 JAMA Data Brief: A recent health survey from the Annenberg Public Policy Center shows only 13% of US adults can identify the blood pressure reading that signifies #hypertension, one of many knowledge gaps related to the condition. ja.ma/4nGtj9b

Among patients with locoregionally advanced nasopharyngeal carcinoma, toripalimab combination therapy without concurrent cisplatin was a feasible treatment with high efficacy in failure-free survival and low toxicity. ja.ma/4nzG2KD

💬 Viewpoint: Despite women facing higher rates of chronic illness and unique gynecological disorders, federal health leaders have insufficiently prioritized women's health in chronic disease research. ja.ma/4pofLkp

Although EBV can cause complications after a transplant, less than 14% of EBV-negative children received kidneys from EBV-negative donors, who mostly went to low-risk EBV-positive adults. ja.ma/4nyUNgL

In children 6-months after heart transplant, everolimus with low-dose tacrolimus was as effective as standard therapy in preventing major complications and showed potential benefits for kidney function and reduced cytomegalovirus infection. ja.ma/4gyS1WK

Superficial vein thrombosis (SuVT) is characterized by thrombus in the superficial veins, typically in the lower or upper extremities. This Review summarizes the diagnosis and treatment of SuVT. ja.ma/3K6OzGD

#GLP1 medicines now address weight loss and other health conditions through innovative formulations and expanded indications, highlighting key questions about their efficacy and safety. ja.ma/4n81Ptf

This Viewpoint from the FDA and the Center for Biologics Evaluation and Research discusses institution of a class Safety Labeling Change for mRNA #COVID19 vaccines. ja.ma/3K4yJwa

Whether to use #SSRIs during pregnancy involves balancing the mental health needs of pregnant people with potential fetal risks. But some experts worry a recent FDA panel didn’t fully consider these complexities. ja.ma/41SPEYD

Receiving a diagnosis of mild cognitive impairment or dementia is necessary for patients and care partners to access appropriate care and support. This Insights explores strategies for effectively communicating a diagnosis to patients and care partners. ja.ma/47SaGdP

JAMA Perspective: How the vocabulary used to describe the way US health care is increasingly governed by the rules, values, and practices of other sectors of the market economy. ja.ma/3K775P0

GLP-1 medicines continue to challenge conventional wisdom, with multiple new indications, molecules and mechanisms. Maria Gonzalez Rellan @uoftmedicine.bsky.social provides an update @jama.com jamanetwork.com/journals/jam...?

“As scientists, it is our responsibility to communicate to the citizens of our nation so that we can work together to ensure their health and the health of their children.” - Lucy Shapiro, #LaskerAward winner 🧪 #Lasker2025 #scicomm @JAMA.com

“Rewriting the Chapter on Cystic Fibrosis” #LaskerAward winner Michael Welsh writes in @JAMA.com about key moments that led to transforming #cysticfibrosis from a death sentence into a manageable condition. 🧪 #Lasker2025

📌 Editor’s Choice from this week's issue of #JAMA: ➡️ FDA Panel Casts SSRIs During Pregnancy as Risky—Many Experts Disagree ➡️ Reducing Barriers to Mental Health Care for Physicians ➡️ Stapokibart for Chronic Rhinosinusitis; and more. ja.ma/4eRp9GH

Editorial: Biologic therapies have changed the course of recalcitrant chronic rhinosinusitis with nasal polyps. ja.ma/4nAsyhP

Among patients with severe chronic rhinosinusitis with nasal polyps treated with a daily intranasal corticosteroid, stapokibart reduced polyp size and severity of nasal symptoms at 24 weeks. ja.ma/4ne7rCk