TLDR: Makary, Hoeg, and Prasad were incompetent political hacks and it will take years to undo their damage.

My sister is an expert in computer security and I'd like to encourage folks to explore her (free) substack posts exploring larger patterns in current events--helping us to see the forest even as we're being bombarded every day with leaves, branches, and sometimes trees. ninalewis174247.substack.com

Good plain language summary of a very bad policy proposal. www.nytimes.com/2026/06/09/o...

The push to cut funding from the National Academies of Science will involve illegally impounding funds on the claim that fringe Republican lawmakers understand what constitutes the “gold standard” for science better than the best scientists in America. www.aip.org/fyi/republic...

In children with septic shock, no significant difference was seen in the incidence of death, new renal-replacement therapy, or persistent kidney dysfunction with balanced fluid as compared with 0.9% saline for fluid resuscitation. Full PRoMPT BOLUS trial results: nej.md/4tvygVy #PAS2026

US state-level policy responses to shifting federal guidance varied widely in 2025, with most states acting to preserve #COVID19 vaccination access through standing orders, insurance coverage, or clinician authority. ja.ma/4ckW8Fh

The most impactful clinical ILD study in ages! 🌟 True multidisciplinary collaboration driving progress 🫁 @rogerjlewis.bsky.social @ipfdoc.bsky.social A Statistical Model for Lung Function Trajectory and Mortality in Patients with Fibrotic ILD academic.oup.com/ajrccm/advan... #OpenAccess

This is the face of a lunar scientist who has just been told that the #Artemis II crew saw SEVERAL impact flashes (the flashes when meteors hit the lunar surface) in real time 😃 🌓💥

JAMA Statistical Editor @rogerjlewis.bsky.social MD, PhD, and Natalie Dean, PhD, discuss the test-negative study design, highlighting its role in analyzing effectiveness and minimizing bias in observational studies. 🎧 Listen now: ja.ma/4tl3MF9

I stopped and stared at the price per ounce numbers for a few minutes trying to reproduce Kroger's / Ralph's math, especially since they are misleading in way that would make you buy a larger package that was actually more expensive per ounce.

JAMA Statistical Editor @rogerjlewis.bsky.social, MD, PhD, and Steve Webb, MBBS, MPH, PhD, discuss the key features of platform trials, including adaptive structures, shared control groups, and domain-based randomization. 🎧 Listen now: ja.ma/3Pk33oU

I wonder what decision process or discussion initially led to this course of action, let alone the decision to perpetuate it. It's difficult for me to picture it.

The updated PECARN rule reliably identified low-risk febrile infants, with no missed cases of bacterial meningitis, potentially reducing routine lumbar punctures. bit.ly/3Zkwf1a

Among patients with acute ischemic #stroke due to non–large vessel occlusion, #tenecteplase administered 4.5 to 24 hours after symptom onset increased excellent outcomes but raised the risk of intracranial #hemorrhage. #ISC26 📽️ Watch the video & read the full study: bit.ly/4kgH1yQ

No, I Won't Watch 'The Pitt' www.medpagetoday.com/opinion/pres...

📊 JAMA Guide to Statistics and Methods: The win ratio is a statistical method for hierarchical composite outcomes, offering a patient-centered summary of treatment effects by prioritizing more important clinical events in clinical trials. ja.ma/4qIidSJ

WHO removing Us Flag

An announcement from Noah Wyle and the CDC:

In this podcast, @rogerjlewis.bsky.social, MD, PhD, Senior Statistical Editor for JAMA, speaks with Kendra Sims, PhD, postdoctoral associate at @busph.bsky.social, about how tipping point analysis can help assess the robustness of study findings. Listen now: ja.ma/49fpFi5

Some beautiful keepsakes nurses made for a dying patient's family at Harbor-UCLA.

“I did not resign to make a symbolic point. I resigned because staying silent would have made me complicit. I spoke up because the stakes for children, communities, and our preparedness are too high.” time.com/7338714/dr-d...

Here, here. "Congress must now also exercise its oversight responsibilities to ensure repairs to FDAs current and future capabilities, infrastructure, human resources, and reputation begin as soon as possible." Big deal coming from investors/companies. www.nopatientleftbehind.org/evidence-bas...

Excited to work with @pzettler.bsky.social and @reshmagar.bsky.social on this new project supported by @arnoldventures.bsky.social with the goal of developing a principles-based approach to rebuilding and re-envisioning FDA. moritzlaw.osu.edu/ohio-state-a...

thank you @drdebhoury.bsky.social !!

Our new kitten was discovered alone and outside by a kind soul at approximately four weeks of age (first measured weight was 395 g). She appears to be settling into the household nicely. Our labradoodle is (very gently) trying to ignore her.

In @nytopinion.nytimes.com “Even as my own life is imperiled by the Trump administration’s actions, I understand the populist rage and institutional distrust that drive the Make America Healthy Again movement,” writes Sam Braslow, who has Stage IV melanoma.

Happy Veterans Day! This post is celebrating my mother's service as a WASP--Women Airforce Service Pilot--during WW II, flying P-52s, P-47s, etc. from the factory to bases for subsequent deployment. Flying newly built planes is risky; 38 of the 1074 women died, often due to mechanical failures.

📢 JAMA Senior Statistical Editor @rogerjlewis.bsky.social, MD, PhD, @jamaotolaryngology.com EIC Jay Piccirillo, MD, & @jamaotolaryngology.com Statistics Editor Dorina Kallogjeri, MD, MPH, will be speakers at the 2nd Annual Midwest Critical Appraisal Workshop. See flyer for more details. ⬇️

On halloween there’s nothing spookier than a future without CDC

In children 6 months after heart transplant, everolimus with low-dose tacrolimus was as effective as standard therapy in preventing major complications and showed potential benefits for kidney function and reduced CMV infection. ja.ma/4nWa63L

Calling all early career researchers! Applications are open for the JAMA Editorial Fellowship Program. Individuals interested in becoming journal editors, as well as those looking to learn more about journal review processes, are invited to apply. 🔗 ja.ma/46ZoFMG

It’s a big week for artificial intelligence publications at JAMA. Editors are celebrating the one-year anniversary of the JAMA Summit on #AI and the launch of JAMA+ AI. Today, JAMA published a Special Communication from Summit attendees, a podcast, and calls for papers. 🧵

Emergency physicians will care for everyone who seeks help - day or night, regardless of insurance status, immigration status, or ability to pay. Read more via the link below 🔗 https://bit.ly/47gQwIz

“I fear for public health in our country.” Former CDC Chief Medical Officer @drdebhoury.bsky.social says that the national US public health system has been subjected to a “hostile takeover” and she’s right. We should all share her fears. Kennedy must go. www.theguardian.com/us-news/2025...

Congratulations to Noah Wyle and the cast and crew of #ThePitt for a huge night at the 2025 Emmys! 🌟 Outstanding and well deserved wins across the board. Thank you for all that you do for EM! 👏 @hbomax

Top medical groups warn that HHS Secretary Robert F. Kennedy Jr poses a risk to US public health amid vaccine policy turmoil. Here’s the latest on the mounting pressure to remove him from the HHS. ja.ma/4n5gPb9

Join us at #atmc25 as we explore "Better Trials Through Better Methods" Invited speakers and program details now available - more at www.atmc25.com Secure your ticket today! Early🐦 must end 26/9

It's been a month since a shooter attacked CDC's HQ. As former CDC & HHS leaders, current staff & supporters gather on the anniversary tonight, APHA's Benjamin tells workers: "You are not alone." Hear more from Benjamin on The Nation's Health Podcast, live now: bit.ly/42jIFrJ

From a time when childhood vaccines were just a figment of imagination. Row after row of baby headstones.

Breaking with the CDC, ACOG reaffirms support for #COVID19 vaccination in pregnant people. Here’s what to know. ja.ma/4mTSEMM

In this podcast episode, economist Edward Norton, PhD, of @umich.edu discusses the use of instrumental variable analysis and heterogeneous treatment effects with JAMA Statistical Editor @rogerjlewis.bsky.social, MD, PhD. ➡️ Listen now:

Still on my 25-year crusade to end all two-sided alpha testing in superiority trials. It's something simulating clinical trials brings out as just plain silly.

Moderna vaccine (www.nejm.org/doi/pdf/10.1... ) 2/2

Yes, it was carefully hidden in the New England Journal of Medicine. Pfizer/BioNTech vaccine (www.nejm.org/doi/pdf/10.1... ) 1/2

🎙️ In this podcast episode, listen to Jody Ciolino, PhD, of Northwestern University, Feinberg School of Medicine, discuss 📊 factorial clinical trial designs with JAMA Statistical Editor @rogerjlewis.bsky.social, MD, PhD. 🔗 Listen now: ja.ma/47o7qq7

📌 You can read all the JAMA, @jamacardiology.com, and @jamanetworkopen.com papers presented yesterday at #ESCCongress 2025. ja.ma/3HNjMxM

📌 Attend "Innovation and Integration in Cardiovascular Medicine" session at #ESCongress 2025, joint session with @jama.com and JAMA Cardiology. 🗓️ Monday, September 1 at 8:15 AM. ➡️ Zagreb - Hall 10 ✅ Featuring JAMA editors @kbibbinsdomingo.bsky.social and Greg Curfman.

A woman who was 20 weeks pregnant fed her toddler son raw milk. He contracted Campylobacter and then passed the infection to her; she progressed to sepsis, and had a miscarriage. She is suing the business that sells the raw milk, saying she didn’t know the risk. Don’t feed your kids raw milk.