This is a policy choice. As Dr. Gottlieb recently put the issue on CNBC: if we substantially reduce vaccination rates, "we're going to have to build new pediatric hospitals." www.youtube.com/watch?v=e8CJ...

Regulating DTC #microbiome tests academic.oup.com/jlb/article/... "...often misleading to consumers..." "...the tests lack analytical and clinical validity." "...may have many 'false positive' or 'false negatives' and can harm consumers." Needed: more stringent regulation!

“The anti-vaccine movement is not a spontaneous expression of grassroots concern. It’s an industry.”

"It is going to get so much worse." For the first of two end-of-the-year episodes of @pandemia.bsky.social, I talked to @drdemetre.bsky.social about what happened in 2025 at the CDC and how he thinks about the future of vaccines and public health in the US. A quick 🧪🧵

The right answer for marijuana is to legalize and regulate. Instead, we’re going to keep the ridiculous Wild West patchwork gray market we have now for THC (worse w/the new restricted definition of hemp) & both subsidize *and* underregulate CBD, assimilating it to pro-supplement woo.

Very well-deserved congrats, @bridgetdooling.bsky.social, but an even bigger congrats to Ohio State for snagging such a superstar scholar, teacher, and colleague in the first place! We're lucky to have you. (And I-O!)

Since 2020, our team has iterated on a model for “rapid research” to help surface, analyze, & resolve rumors about election administration. This work demonstrates an innovative role for researchers to support public sensemaking during rapidly unfolding events. uw.pressbooks.pub/rapidresearc...

"One agency source said at least one division is having to pour all of its resources into reviewing drugs that received a voucher, taking time away from other medical products."

Vaccines cause adults

Summarizing the current state of pricing and coverage for GLP1s in the US with @rachelsachs.bsky.social in @nejm.org this week! Read it before things change (again)! www.nejm.org/doi/full/10....

I am *really* excited about this work and the opportunity to work with @hollylynchez.bsky.social & @reshmagar.bsky.social, and grateful to @arnoldventures.bsky.social for the support. We're looking to hire a post-doc, please apply or send candidates our way! postdocs.yale.edu/posts/2025-1...

Now up at Health Affairs Forefront, Kristi Martin and I identify important aspects of the 2027 Medicare drug price negotiation cycle, including its interactions with other IRA drug pricing reforms. www.healthaffairs.org/content/fore...

Lots more detail in the paper (jamanetwork.com/journals/jam...), but our findings provide the first evaluation of FDAAA and its enhanced safety-related regulatory authorities, and its impact on drug safety and public health, and informs current PDUFA VII negotiations! @reshmagar.bsky.social (5/5)

New paper from @yalecrrit.bsky.social out today in @jamainternalmed.com - The 2007 US Food and Drug Administration (FDA) Amendments Act (FDAAA) expanded the agency's safety-related regulatory authorities, including enhanced postmarketing safety surveillance and new clinical study requirements (1/5)

As @bridgetdooling.bsky.social and I argue in a new paper (link below), corporate directors play a role in law enforcement. They have a special duty to ensure their companies don't break the law. It is heartening, therefore, to see a few companies stand up for the rule of law. As they ought.

Love this optimism! #GoTeam! Chris Whitty: Why health misinformation spreads www.bmj.com/content/391/... "Through every single one of the past 160 years there was extensive misinformation about health—and yet the improvements continued." "This is a battle that is winnable."

As many others have posted, a must-read by 12 former FDA commissioners laying out what's so deeply troubling about the substance of and process used for recent changes to vaccine policy at FDA: www.nejm.org/doi/full/10.... But @jasonlschwartz.bsky.social perhaps summed it up best 👇

Congratulations to the CMS career staff for completing the negotiations for the 2027 cycle of the Medicare drug price negotiation program - the negotiated prices are now public. More later, but for now one note on attempts to compare these savings to the 2026 savings. 1/2 www.cms.gov/files/docume...

It's up! www.yalejreg.com/nc/trump-reg...

Tragic. Critical to promote reliable information from the biomedicine community.

Yikes.

This is going to be a terrific discussion re: AI & health insurance coverage decisions that’s open to the public if you are interested. @umnconsortium.bsky.social

When the evidence in favor of vaccination is compelling, CDC should make a recommendation ... and the American people deserve to hear it. Our case in @jama.com w/ Tom Frieden and William Scaffner jamanetwork.com/journals/jam...

“We can have an active, robust discussion as a group of medical experts spontaneously, and so we’re doing more of that,” Makary said of his preference for convening roundtables. Guess what roundtables don't have? FACA requirements to occur in public with the opportunity for public comment.

Ridiculous. So maddening. Yes, complex. But there is NO doubt that antivaxx misinformation big part of problem. Canada loses measles elimination status after three decades, health agency says www.reuters.com/business/hea...

Seems like a good time to do a special issue of @jhppl.bsky.social on the Politics of Private Health Insurance. Call for papers will be out soon, so stay tuned. There’s seem to be, uh, a few politically relevant topics to discuss. @mirandayaver.bsky.social @adrianna.bsky.social

For #adlaw folks: Due to logistical issues from the federal gov't shutdown, ABA Admin Law has replaced its usual fall conference with a shorter but free online event on 11/21. Registration is required, but it's 6.5 hrs of free, quality CLE on admin law topics. events.americanbar.org/event/a13a77...

Thanks again to @stemcellnetwork.ca, and all the speakers, poster presenters, and attendees at #TMM2025 - was a delight to be part of this wonderful event!

Perhaps relevant today, a framework for understanding how many election rumors mislead.

It has been a great day at @stemcellnetwork.ca's #TMM2025! And I'm looking forward to more tomorrow, including joining @jsnyder.bsky.social, @lr-bg.bsky.social, & @deanshamess.ca first thing, for a discussion on public trust in science and policy decisions.

100% (at least in my neighborhood in Columbus, maybe the only one with trick or treat tonight, instead of last night!).

Thank you, @cidrap.bsky.social, for covering our new @nejm.org review of Covid-19, RSV, and influenza immunizations. Check it out: cidrap.umn.edu/covid-19/meta-analysis-covid-rsv-flu-vaccines-fall-provides-sea-data-showing-efficacy-safety

The NIH has insisted there are no banned words But, an analysis by @jeremymberg.bsky.social found over 700 hundred grants changed their titles from '24 to '25 Some see it as a small price to pay to keep their grant, but others are worried about what comes next www.statnews.com/2025/10/29/n...

👇👇 Now in @jama.com: @greerdonley.bsky.social, Lewis Grossman & I explain that these preemption cases, while specifically about mifepristone, have implications for FDA and state drug regulation, biomedical innovation, and patient access more generally. jamanetwork.com/journals/jam...

My paper with @patentscholar.bsky.social on how AI increases plagiarism risk in student and academic writing, what law should do about it (nothing), and what schools should do about it (quite a bit) is now published in the University of Chicago Law Review lawreview.uchicago.edu/online-archi...

Excited to see this published as part of @jhppl.bsky.social's 50th anniversary edition! The balance between the role of the government and the private sector even in traditionally public programs has continued to evolve in ways which may become even more important in the future.

"The Dahlbergs feel it’s up to them to protect their two surviving children from vaccine-preventable diseases. They can’t rely on their government anymore." Absolutely heartbreaking.

This is a fantastic, well-supported 3-year post-doc in our Division of Medical Ethics at Penn. Please share (and apply if interested!)

This will be a test of whether key federal agencies (USDA, HHS, etc.) can work with academic communities, especially those with strong vet, med and public health schools, and with states and counties to solve this problem. www.nytimes.com/2025/10/22/h...

New publication from me: Henry T. Greely, Depopulation Hysteria, U.C. Davis On Line Law Review, 59:117-136 (Oct. 2025). I argue that the increasing drumbeat of concern about falling human populations is somewhat exaggerated but also threatens women's rights. lawreview.law.ucdavis.edu/archives/59/...

ICYMI, in a recent article in @jama.com with @dusetzinas.bsky.social and Thomas Hwang, we explored this issue in detail and argued that "not all combination drugs should be treated separately for negotiation purposes." 4/4 jamanetwork.com/journals/jam...

Great take by @hollylynchez.bsky.social & @reshmagar.bsky.social! "Public trust in authorities like the FDA is already depleted. Demanding that the agency greenlight more rare disease drugs, evidence be damned, will make this problem worse — and likely won’t leave rare disease patients better off."

"Tiburon could become just the third municipality in the country to ban all sales of tobacco products. The idea originated from a group of high school students in town." www.ktvu.com/news/tiburon...

FDA secures major win as SCOTUS lets stem cell clinic ruling stand ipscell.com/2025/10/fda-... #stemcells #stemcell RFK Jr.

Great reporting by @lizzylawrence.bsky.social. Great, insightful quotes from @reshmagar.bsky.social, @nathancortez.bsky.social & @rachelsachs.bsky.social. Not great news, to say the least, for public health, innovation, or any of us.

For more information about the Friday night massacre at CDC, I wrote up an analysis of who got terminated and what that means for public health. Grateful to @saveamericamvmt.bsky.social for supporting and amplifying. We are in really terrible trouble. rasmussenretorts.substack.com/p/the-death-...

Extracting Drugs from Nature Is Hard www.mcgill.ca/oss/article/... @jonathanjarry.bsky.social "The fact that a natural molecule has some anticancer activity when added to cells in a plastic dish does not mean it will be safe & effective when given to a patient" Reality: most fail in human studies.

Terrible and terrifying news for all of us.

Isn't this the opposite of what HHS leadership said their policies would do? A new KFF poll shows public trust in the Centers for Disease Control and Prevention (CDC) is now at its lowest level since the start of the COVID-19 pandemic. www.cidrap.umn.edu/childhood-va...