Quick takes: Whooping cough in Texas, polio in 2 nations, Canada Salmonella outbreak Texas health officials say the state has a seen a four-fold increase in whooping cough cases compared with last year.

Lassa vaccine candidate provides encouraging results in phase 1 trial The rVSVΔG-LASV-GPC vaccine caused no serious adverse events and produced a strong immune response in healthy adults in the US and Liberia. www.cidrap.umn.edu/l...

#Nirsevimab prevents #RSV cases in young kids for 1 year but maybe not beyond, data suggest The findings have implications for scheduling repeat dosing in eligible children, the authors say. www.cidrap.umn.edu/r...

Five new #avian flu outbreaks confirmed in ducks, turkeys in 3 US states In Michigan, 113,000 birds were affected on a turkey farm, the state's third detection in commercial turkeys in less than a week. www.cidrap.umn.edu/a...#avian Photo: Andew-M-Whitman / Flickr cc

Next up for Vaccine Integrity Project: reviewing data on birth dose of hepatitis B vaccine The review will look at decades of data on the safety, efficacy, and public health impact of administering the hepatitis B shot at birth. www.cidrap.umn.edu/h...

WHO voices concerns about equitable access to novel TB vaccines In a new report, the WHO says financing and access strategies need to be implemented to ensure the demand for future TB vaccines doesn't outstrip supply. www.cidrap.umn.edu/t...

High rates of multidrug-resistant bacteria found in West Bank hospitals More than one third of the 10,007 bacterial isolates collected from 13 West Bank hospitals were classified as multidrug-resistant. www.cidrap.umn.edu/a...

Analyses: High-dose #flu vaccine better protects against hospitalization, infection than standard-dose High-dose vaccine was 40% more effective against hospitalization than the standard-dose version. www.cidrap.umn.edu/i...

Intranasal vaccine against #H5 avian flu provokes broad immune response in adults in phase 1 trial Even without a booster, the vaccine triggered mucosal and systemic immunity. www.cidrap.umn.edu/a...

Rift Valley fever cases in Senegal, Mauritania top 400 All but 46 of the confirmed cases have been in Senegal. www.cidrap.umn.edu/r... Photo: Albert Gonzalez Farran, UNAMID / Flickr cc

Lassa fever’s death toll in Nigeria climbs in 2025 The deaths are likely due to poor health-seeking behavior among patients who seek medical intervention too late. www.cidrap.umn.edu/l... Photo: NIAID/Flickr cc

The Vaccine Integrity Project @CIDRAP is conducting an independent review of the evidence supporting the long-standing recommendation for universal #HepatitisB vaccination at birth. In Sept, CDC’s vaccine advisers tabled a vote on the birth dose and asked for more data. 🔗 tinyurl.com/4sy3wwa7

More measles cases reported in Utah, Arizona The measles outbreak along the Utah-Arizona border is the nation's second largest this year. www.cidrap.umn.edu/m...

Study: Demographic shifts will fuel increase in drug-resistant bloodstream infections in Europe The modeling study predicts the rate of drug-resistant BSIs will rise sharply in Europe over the next 5 years, driven primarily by an aging population. www.cidrap.umn.edu/a...

FDA approves new IV antibiotic for complicated urinary tract infections The intravenous formulation of fosfomycin has a novel mechanism of action and no known cross-resistance to other antibiotic classes.

Data: Risks of vascular, inflammatory conditions in kids higher after #COVID infection than vaccination Over 6 months, COVID infection led to 2.24 extra cases of myocarditis or pericarditis per 100,000 children, versus 0.85 per 100,000 after vaccination. www.cidrap.umn.edu/c...

The order of pre-#COVID chronic conditions may best predict long-COVID risk The most common disease trajectories involved mental illnesses and neurologic, respiratory, and metabolic or digestive diseases. www.cidrap.umn.edu/c...

Trial data show ensitrelvir has potent antiviral activity against COVID-19 Data from a phase 2 randomized controlled clinical trial show ensitrelvir accelerated viral clearance in patients with early symptomatic COVID-19. www.cidrap.umn.edu/c...

Some common viruses may steeply raise risk of cardiovascular disease The authors noted that viral infections trigger the immune system to release substances that lead to inflammation and increase the risk of blood clots. www.cidrap.umn.edu/i...

Antimicrobial peptides show promise against Salmonella in chickens, study finds In lab experiments and chickens, peptides derived from a strain of probiotic bacteria inhibited Salmonella strains that commonly cause foodborne illness. www.cidrap.umn.edu/a...

Cincinnati hospital looks at possible nosocomial Legionnaires' So far the site of exposure is unknown. www.cidrap.umn.edu/l... Photo: Andrew Magill / Flickr cc

Avian flu strikes turkey farms in Dakotas, large egg facility in California Elsewhere two large poultry outbreaks were reported in Lagrange County, Indiana. www.cidrap.umn.edu/a... Photo: Antyoko Rostriardi / iStock

Only certain types of bats host viruses with high epidemic potential, research suggests Those found in coastal South America, Southeast Asia, and equatorial Africa are more likely to carry pathogens such as #SARS-CoV-2. www.cidrap.umn.edu/c...#SARS-CoV-2. Photo: Adam Zdebel / Flickr cc

CIDRAP joins global partners in the DeZi Network — uniting 15+ countries to strengthen dengue & Zika surveillance and response across Africa and Asia. 🔗 www.imperial.ac.uk/news/269973/... #GlobalHealth #Dengue #Zika

Trial data highlight sustained protection from dengue vaccine Findings from a phase 3 trial show Qdenga, Takeda's live-attenuated dengue vaccine, provided 61.2% vaccine efficacy against infection and 84.1% against hospitalization after 4.5 years. www.cidrap.umn.edu/d...

Preventive non–beta-lactam antibiotics linked to higher risk of surgical-site infections In nearly 350,000 Swiss patients, use of non–beta-lactams before surgery was associated with a nearly two-fold increase in SSI risk compared with beta-lactams. www.cidrap.umn.edu/a...

US hot spots see more measles cases Aleksandr Zyablitskiy/iStock www.cidrap.umn.edu/m...

CDC: Salmonella outbreak linked to powder supplement So far 11 people in 7 states have been sickened. www.cidrap.umn.edu/s...

#COVID vaccination cuts risk of long-term symptoms in teens by over a third, data suggest The vaccine is unique in having this effect on progression to a chronic condition, despite infection, the researchers say. www.cidrap.umn.edu/c...

Glucocorticoids cut risk of death from #pneumonia in low-resource settings, trial shows The results are likely to be more relevant to patients in sub-Saharan Africa than to those in high-resource settings, the authors say. www.cidrap.umn.edu/p...

Deadly multistate Listeria outbreak tied to prepared pasta meals expands Seven new illness and 2 additional deaths have been confirmed in the outbreak, which has grown to 27 cases and 6 deaths. www.cidrap.umn.edu/l...

My @cidrap.bsky.social Op-Ed: "Vaccine effectiveness and safety: What the numbers truly mean in 2025" Our review provides extensive data on Covid-19, RSV, and flu, though interpreting these numbers requires understanding the distinct context surrounding each. www.cidrap.umn.edu/covid-19/cid...

Support for measles vaccination drops amid growing confusion about the disease, US poll shows 23% of US adults say RFK Jr recommends kids get the #measles vaccine, 29% say he does not recommend it, and 48% aren't sure www.cidrap.umn.edu/m...#measles Photo: Gage Skidmore/Flickr cc

New coronavirus subspecies with #SARS-CoV-2–like mutation discovered in Brazilian bat The bat harbored the BRZ batCoV virus, which the researchers say has likely been silently circulating in Latin America for some time. www.cidrap.umn.edu/c...

Oral vaccine protects against Salmonella Paratyphi in human challenge trial The two-dose oral vaccine had an efficacy of 73% in healthy volunteers who were exposed to Salmonella Paratyphi A, which causes paratyphoid fever. www.cidrap.umn.edu/s...

CIDRAP Op-Ed: Vaccine effectiveness and safety: What the numbers truly mean in 2025 Our systematic rvw published this week shows that rigorous, transparent evidence synthesis can persist even when traditional advisory processes falter by Jake Scott, MD www.cidrap.umn.edu/c...

Kids exposed to #COVID in utero may be at higher risk for autism, other brain problems But the overall odds are likely low and may well have ebbed since the pandemic peak. www.cidrap.umn.edu/c...

Suspected measles case-patient refuses testing in Salt Lake County Prior to this year, there had only been one confirmed measles case in Utah since 2020. www.cidrap.umn.edu/m...

New Osterholm Update podcast episode! @mtosterholm & @cvdall discuss a recent paper from the Vax Integrity Project, a CIDRAP-NEJM Evidence collaboration, latest measles & respi virus data, & how the govt shutdown is affecting public health surveillance www.cidrap.umn.edu/a...

Avian flu detected in house mice in Washington state Grant County recently had seven avian flu detections in wild birds. www.cidrap.umn.edu/a... Photo: David DeHetre / Flickr cc

Review: Human #H5N1 avian flu cases can be asymptomatic, and the virus likely spreads among people The findings highlight a critical gap in many national and global H5N1 surveillance systems. www.cidrap.umn.edu/a...

WHO too reliant on funding from donor organizations, paper argues Researchers say reliance on earmarked voluntary contributions from external donors like the Gates Foundation undermines the WHO's independence. www.cidrap.umn.edu/p...

CIDRAP and CEPI launch resources to track development of coronavirus vaccines The revamped open-access site tracks scientific progress toward the development of broadly protective coronavirus vaccines www.cidrap.umn.edu/c...

Serious mental illness tied to increased risk of long #COVID Participants with schizophrenia, bipolar disorder, or recurrent major depressive disorder were at a 10% higher risk of persistent symptoms. www.cidrap.umn.edu/c...

🚀 CIDRAP has launched a new digital home for the Coronavirus Vaccines R&D Roadmap Initiative — a global, open-access platform to track progress toward broadly protective coronavirus vaccines. 🔗 Explore the site: cvr.cidrap.umn.edu

Antiviral prescribing for kids at risk of severe flu declined during COVID, study finds Antiviral prescribing for influenza-positive kids at risk of severe illness in US emergency departments declined 53% compared with the prepandemic period. www.cidrap.umn.edu/i...

Meta-analysis of #COVID, #RSV, #flu #vaccines for fall provides 'sea of data' showing efficacy, safety The large-scale project was conducted by CIDRAP's Vaccine Integrity Project. www.cidrap.umn.edu/c...#COVID,#RSV,#flu#vaccinesoto: US Army Garrison Fort George G. Meade / Flickr cc

Today in @NEJM: The Vaccine Integrity Project reviews the latest data on flu, COVID, & RSV immunizations, filling a vital evidence gap for clinicians and the public. Independent science matters more than ever. Read the paper ➡️ www.nejm.org/doi/full/10.1056/NEJMsa2514268

Outbreaks in Southwest, South Carolina grow as US tracks 40 more measles cases The national total is 40 more cases than last week. www.cidrap.umn.edu/m...

Quick takes: Nipah vaccine project, global decline in cholera, avian flu in US wild birds In September cholera cases were down 27% from August.