Nilsson lab
@nilssonlab.bsky.social
π€ 367
π₯ 99
π 20
Arrived in Wurzburg to get the latest om phosphatases!
about 2 months ago
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Returning from two great days at ICR in London to visit Norman Davey and many others. Need 20 days next time!
3 months ago
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reposted by
Nilsson lab
5 months ago
The @embo.org
#chromoploidy2025
is over. It was an amazing workshop organized by a perfect match of scientists and friends
@mcclellandlab.bsky.social
@bendavidlab.bsky.social
@stesantaguida.bsky.social
@foijer-lab.bsky.social
, Elsa Logarinho, Caroline Audouin and myself
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Here we go - 4 days of excellent science in Italy
5 months ago
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Nilsson lab
IDPSeminars
6 months ago
Back again TOMORROW (Thursday April 3rd) for another IDPSeminars! Noon central time - sign up for the webinar here
forms.gle/3yCHeYvuuqLh...
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Come join us for the phosphatase meeting this summer! Deadline approaching for signing up for this great meeting.
meetings.embo.org/event/25-pho...
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Phosphatases: from basic research to translation
Phosphatases have been considered undruggable for decades. However, recent breakthroughs with the first small molecule phosphatase inhibitors for cancer immunotherapy now in clinical trials have resuβ¦
https://meetings.embo.org/event/25-phosphatases
6 months ago
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Happy to share our latest work on phosphoprotein phosphatase (PPP) regulation. We integrate CRISPR knockout and focused base editor screens to uncover the regulatory landscape of PPPs (more below). Great collaboration with the Zhu, Davey, Kettenbach and Ogris labs.
www.biorxiv.org/content/10.1...
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A functional map of phosphoprotein phosphatase regulation identifies an evolutionary conserved reductase for the catalytic metal ions
Serine/Threonine phosphoprotein phosphatases (PPPs, PP1-PP7) are conserved metalloenzymes and central to intracellular signaling in eukaryotes, but the details of their regulation is poorly understood...
https://www.biorxiv.org/content/10.1101/2025.02.12.637884v1
7 months ago
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reposted by
Nilsson lab
Prasad Jallepalli, MD, PhD
7 months ago
www.nytimes.com/2025/02/14/o...
An eloquent defense of American science by Harold Varmus, a Nobel Prize winning scientist during his days at UCSF, former director of the NIH and NCI, and former President of Memorial Sloan Kettering Cancer Center (full disclosure β itβs where I work)
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Opinion | American Science is Under Attack (Gift Article)
The Trump administration hobbles research and endangers the public health.
https://www.nytimes.com/2025/02/14/opinion/trump-public-health-funding-nih.html?unlocked_article_code=1.w04.GXc-.MiiViZyGCwLT
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reposted by
Nilsson lab
@tim_stasevich
7 months ago
Making intrabodies from antibodies just got easier! Learn how we made ππ΅ intrabodies to bind and light up peptides and histone modifications in live cells. And thanks to Academia, all sequences are freely available. (video credit: Yuko Sato @YukoSatoT2) (1/15)
www.biorxiv.org/content/10.1...
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reposted by
Nilsson lab
The Groth lab
7 months ago
π¨πππ£π¨π« ππ¨π ππ₯ππ«π!π¨The Groth
@groth-anja.bsky.social
, Mailand, Nilsson
@nilssonlab.bsky.social
& Krietenstein
@nilskrietenstein.bsky.social
labs are hiring π ππ‘π&π©π¨π¬πππ¨ππ¬ to join the new Center for Epigenetic Cell Memory (EpiC)Β in Copenhagen, Denmark. Apply here:
tinyurl.com/yvd93na2
& please share!
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6 Postdoctoral and PhD positions in Center for Epigenetic Cell Memory (EpiC)
The Center for Epigenetic Cell Memory (EpiC) is a new Center of Excellence that will be established based on funding by the Danish National Research Foundation.
https://tinyurl.com/yvd93na2
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Goodbye to my office for the last 14 years. Time to pack down and head for new adventures
8 months ago
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reposted by
Nilsson lab
Ellenberg Lab
9 months ago
Congratulations to
@andibrunner.bsky.social
and the team, and many thanks to the lab of Jan-Michael Peters for support! We found that the interphase and mitotic chromatin loop organization have more in common than previously thought: In both stages big loops are built first, small ones second
add a skeleton here at some point
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Interesting read - large scale base editor screen to probe S,T and Y function in RPE1 cells.
www.nature.com/articles/s41...
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Functional profiling of serine, threonine and tyrosine sites - Nature Chemical Biology
The use of an adenine base editor enables identification of functional serine, threonine and tyrosine residues that impact cell fitness on a genome-wide scale with possible involvement in phosphorylat...
https://www.nature.com/articles/s41589-024-01731-0
9 months ago
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reposted by
Nilsson lab
Amelie Stein
9 months ago
Want to come work with me? Short postdoc opportunity. Deadline tomorrow β‘οΈ
jobportal.ku.dk/videnskabeli...
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Postdoc of molecular data science
https://jobportal.ku.dk/videnskabelige-stillinger/?show=163158
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reposted by
Nilsson lab
Carlos Conde
9 months ago
Just in time for Christmas. Latest from the lab
www.biorxiv.org/content/10.1...
great collaborative effort with
@nilssonlab.bsky.social
@andrea-musacchio.bsky.social
and Mathieu Bollen.
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POLO kinase inhibits Protein Phosphatase 1 to promote the Spindle Assembly Checkpoint and prevent aneuploidy
Protein phosphatase 1 (PP1) is essential for spindle assembly checkpoint (SAC) silencing and mitotic exit, but its regulation during mitosis remains ill-defined. Here, we demonstrate in vitro and in D...
https://www.biorxiv.org/content/10.1101/2024.12.23.630043v1
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In case you still haven't found the perfect Xmas present:
meetings.embo.org/event/25-pho...
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Phosphatases: from basic research to translation
Phosphatases have been considered undruggable for decades. However, recent breakthroughs with the first small molecule phosphatase inhibitors for cancer immunotherapy now in clinical trials have resuβ¦
https://meetings.embo.org/event/25-phosphatases
9 months ago
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Lad xmas party - merry xmas to everyone!
9 months ago
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Goodbye to Mads and good luck with the PhD. Thanks for the PP2A-B55 in lego - awesome!
9 months ago
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Thanks to all the organisers for a great meeting. Many discussions and ideas.
9 months ago
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On our way to the FASEB phosphatase meeting with a short stop in LA. Look forward to some excellent days of science and sun.
10 months ago
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reposted by
Nilsson lab
Magnus Kjærgaard
10 months ago
Do you need a starting pack of researcher working on intrinsically disordered proteins? Well, you might head over to
@idpseminars.bsky.social
and hit followers. Tw***** was important for the birth of IDPseminars and for spreading the word. It would be cool to re-kindle that community here.
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We are establishing an open access infrastructure for optical pooled screening and looking for a computational scientist to join us for this great adventure. Come to Copenhagen and be part of a great scientific community:
candidate.hr-manager.net/ApplicationI...
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Computational scientist for new optical pooled screening infrastructure at the Danish Cancer Institute
Computational scientist for new optical pooled screening infrastructure at the Danish Cancer Institute Do you want to be part of a state-of-the-art core facilit
https://candidate.hr-manager.net/ApplicationInit.aspx?cid=1572&ProjectId=145441&DepartmentId=18958&MediaId=5&SkipAdvertisement=False
10 months ago
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