CRISPR screening season before holiday season

I have a PhD opening in my lab for an exiting project using base editor screens to find novel drug targets. Please help spread the word. candidate.hr-manager.net/ApplicationI...

Our latest research in collaboration with @nilssonlab.bsky.social, @andrea-musacchio.bsky.social and Mathieu Bollen reveals a new regulatory strategy employed by cells to control PP1 in mitosis. Check it out in @currentbiology.bsky.social www.sciencedirect.com/science/arti...

John Gurdon, former Group Leader and Head of @cellbiol-mrclmb.bsky.social has died. Despite calling himself a "total non-intellectual” his work to reprogramme somatic cells to pluripotent stem cells transformed the field of developmental biology. More: www2.mrc-lmb.cam.ac.uk/john-gurdon-... #LMBNews

Arrived in Wurzburg to get the latest om phosphatases!

Returning from two great days at ICR in London to visit Norman Davey and many others. Need 20 days next time!

The @embo.org #chromoploidy2025 is over. It was an amazing workshop organized by a perfect match of scientists and friends @mcclellandlab.bsky.social @bendavidlab.bsky.social @stesantaguida.bsky.social @foijer-lab.bsky.social, Elsa Logarinho, Caroline Audouin and myself

Here we go - 4 days of excellent science in Italy

Back again TOMORROW (Thursday April 3rd) for another IDPSeminars! Noon central time - sign up for the webinar here forms.gle/3yCHeYvuuqLh...

Come join us for the phosphatase meeting this summer! Deadline approaching for signing up for this great meeting. meetings.embo.org/event/25-pho...

Happy to share our latest work on phosphoprotein phosphatase (PPP) regulation. We integrate CRISPR knockout and focused base editor screens to uncover the regulatory landscape of PPPs (more below). Great collaboration with the Zhu, Davey, Kettenbach and Ogris labs. www.biorxiv.org/content/10.1...

www.nytimes.com/2025/02/14/o... An eloquent defense of American science by Harold Varmus, a Nobel Prize winning scientist during his days at UCSF, former director of the NIH and NCI, and former President of Memorial Sloan Kettering Cancer Center (full disclosure — it’s where I work)

Making intrabodies from antibodies just got easier! Learn how we made 𝟭𝟵 intrabodies to bind and light up peptides and histone modifications in live cells. And thanks to Academia, all sequences are freely available. (video credit: Yuko Sato @YukoSatoT2) (1/15) www.biorxiv.org/content/10.1...

🚨𝐌𝐚𝐣𝐨𝐫 𝐉𝐨𝐛 𝐀𝐥𝐞𝐫𝐭!🚨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring 𝟔 𝐏𝐡𝐃&𝐩𝐨𝐬𝐭𝐝𝐨𝐜𝐬 to join the new Center for Epigenetic Cell Memory (EpiC) in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!

Goodbye to my office for the last 14 years. Time to pack down and head for new adventures

Congratulations to @andibrunner.bsky.social and the team, and many thanks to the lab of Jan-Michael Peters for support! We found that the interphase and mitotic chromatin loop organization have more in common than previously thought: In both stages big loops are built first, small ones second

Interesting read - large scale base editor screen to probe S,T and Y function in RPE1 cells. www.nature.com/articles/s41...

Want to come work with me? Short postdoc opportunity. Deadline tomorrow ⚡️ jobportal.ku.dk/videnskabeli...

Just in time for Christmas. Latest from the lab www.biorxiv.org/content/10.1... great collaborative effort with @nilssonlab.bsky.social @andrea-musacchio.bsky.social and Mathieu Bollen.

In case you still haven't found the perfect Xmas present: meetings.embo.org/event/25-pho...

Lad xmas party - merry xmas to everyone!

Goodbye to Mads and good luck with the PhD. Thanks for the PP2A-B55 in lego - awesome!

Thanks to all the organisers for a great meeting. Many discussions and ideas.

On our way to the FASEB phosphatase meeting with a short stop in LA. Look forward to some excellent days of science and sun.

Do you need a starting pack of researcher working on intrinsically disordered proteins? Well, you might head over to @idpseminars.bsky.social and hit followers. Tw***** was important for the birth of IDPseminars and for spreading the word. It would be cool to re-kindle that community here.

We are establishing an open access infrastructure for optical pooled screening and looking for a computational scientist to join us for this great adventure. Come to Copenhagen and be part of a great scientific community: candidate.hr-manager.net/ApplicationI...