@bendavidlab.bsky.social
📤 960
📥 199
📝 12
Investigating
#Aneuploidy
in
#Cancer
@TelAvivUniv
Our paper on aneuploidy driver identification just published in
@cp-cellreports.bsky.social
. Great work by Ron Saad, jointly supervised by the Shamir and Ben-David labs!
www.cell.com/cell-reports...
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https://www.cell.com/cell-reports/pdf/S2211-1247(25)01226-4.pdf
18 days ago
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Thank you
#SchmidtSciences
for this amazing opportunity!
about 2 months ago
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1/2 Not a good time for celebrations — the war in Gaza must end NOW! Nonetheless, I’m happy to share that I’ve been promoted to Full Professor at TAU! Just as I’m about to start my Sabbatical with
@kopslab.bsky.social
&
@renemedema.bsky.social
in Utrecht 🇳🇱.
3 months ago
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Happy to share our new comprehensive Review paper on the targeting of aneuploidy for cancer therapy. Just published in
@cp-trendscancer.bsky.social
.
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https://pdf.sciencedirectassets.com/313336/AIP/1-s2.0-S2405803325000974/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEFQaCXVzLWVhc3QtMSJIMEYCIQCKHx75yCbMIaJN6pwvW7Pccy6yVXUMQnSpH%2BfnznnDdgIhAJ%2BGdVL6n6BiUh38ML34fY5xWj9reQ7wr%2FyyL33EHdLTKrwFCP3%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEQBRoMMDU5MDAzNTQ2ODY1IgwaiR2F8j%2BE3%2FNir30qkAWVxOucGAsleD7ilw36NnycwJHAqwfauFV5xccXQ9K0d3YRCA1ZICJ1Zj67NUrnb82yWj538jHlane7wp9L%2BVc1V4BnZWzHW4GDulvD26McWKwpQhBY8Dkp24qguSK32e87yaRkAiDsfXMaw29LvvT96rsgcoWTiwfAT7q4%2FpW%2FHq3BW75Ucm6Dobb%2BEwgWw4S6BrogoxiOSwSRrX7ONNsF%2FPCdw%2FefFejabmb16XXn1JPglpWZ8GohNQ2JMZFXN6IpnuGW0Xx%2BlaebpeQv4uYjkUWG5OixqnlLBkRhCWqB38uNh9D8QQW3SuCOrKohaB455Y%2BUAlS%2FV6YhT9NBHBaJT7dj87RqdG%2B%2Fft8f1wf31e0MkZmWW1BvKaC71NvHYXrk77t91OaoSbeNs9GVg9Q6nNLoGEY2TCmQKSVAbD1TzqYdhCq6yE0cYFJNFAPQEeL8jUYVFMMfxj%2Bxm7EKEjniUficJ%2FdORfkLakL010CozZGSDT1IoixIFeL%2FLdihoAQHpZgWf1fVNeXZy%2BuPu1rBPXGT1srhE22zlmij3Oj9oplDD7hGAi9d%2FoXrd5zOZnh16xVE7opqm%2F6xu%2FkTj6Fx0WAMhBrKeOQlRBvuHXkdrfGJFGJf4H6HGJ%2FEJOaOfOvUGsYmWF55CDwnkUQ0Q%2BE4k2%2FgfLdAziFPNZfdJD8u8ptJegiWcVMfyjVVa2pAasana8Es4fbuE2%2BjKPr76kWIDefdJVjjXjT%2FeeKGcMFDlMzRsDbnnQ%2BUaL83jC%2BtsLSbF4EApi%2FjeMDlaEcoXiFKdGxyGHi%2FDfZ9YIEO9pTViQ7cDRSnR%2FQhGjFVDUfEhAKkwD9sWASpmzYoh938ci6xs8ES0FiZR97R%2FBnUzL4DoTDip5DBBjqwAS4Clc3R1N4tGezhwH%2FOpkiNwkFpZlKPWRXiAlPddbTIeONblP7G76wmqubTdcwgzQSBiode9r45Tpde7OzeDipEhapUa8wWIMk2jrU%2F90M1hcHu6wFTwu%2F%2F11II%2FNsB8OsFWAF%2FsZ8KbHxzdFz6wG8Z01FVz5dWLaiY5pb3gWaJ8249BkIkIam5mFPC1RmkbrvVmBmyWKKXhSlYPTL5K0FtCTUbvmrxakrzuLLVU4wJ&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Date=20250514T050023Z&X-Amz-SignedHeaders=host&X-Amz-Expires=300&X-Amz-Credential=ASIAQ3PHCVTYTK2YC642%2F20250514%2Fus-east-1%2Fs3%2Faws4_request&X-Amz-Signature=16bfe3f3df3cb61bc460c95704b8b45b70e235c1efc165adad2923fd333b97ef&hash=0a8f0881293f0a55d6ab47187900b65b11fcb6a07c87e51b007ce555a9aec58f&host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&pii=S2405803325000974&tid=spdf-67ffa027-e03e-4353-9161-0661f36663b1&sid=98539b9f5a082348a3399480d67c992928b9gxrqb&type=client&tsoh=d3d3LnNjaWVuY2VkaXJlY3QuY29t&rh=d3d3LnNjaWVuY2VkaXJlY3QuY29t&ua=130a5e5d0959025003&rr=93f7d4e64dc8c088&cc=il
6 months ago
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reposted by
6 months ago
The @embo.org
#chromoploidy2025
is over. It was an amazing workshop organized by a perfect match of scientists and friends
@mcclellandlab.bsky.social
@bendavidlab.bsky.social
@stesantaguida.bsky.social
@foijer-lab.bsky.social
, Elsa Logarinho, Caroline Audouin and myself
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Excited to get the
#EMBOChromoploidy
meeting started! 3 days of fantastic science and fun in beautiful Stresa are beginning now!
meetings.embo.org/event/25-ane...
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Chromosome Segregation and Aneuploidy
Aneuploidy is a hallmark of cancer and developmental disorders such as Down syndrome. Understanding how cells accomplish faithful chromosome segregation and how chromosomal instability (CIN) impacts …
https://meetings.embo.org/event/25-aneuploidy
7 months ago
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reposted by
Johanna Joyce
8 months ago
We have such an exciting program and speakers for our annual
#EACR
congress 🤩 Thanks to the many, many researchers who already submitted abstracts - and don't forget this week's March 6 abstract deadline ⏰ if you also want to join us in beautiful Lisbon!
2025.eacr.org
@helloeacr.bsky.social
🧪🔬⚕️
add a skeleton here at some point
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Happy to share our new preprint, in which we systematically Identify and prioritize candidate drivers genes that underlie recurrent chromosome-arm losses!
www.biorxiv.org/content/10.1...
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https://www.biorxiv.org/content/10.1101/2025.02.22.639659v1.full.pdf
8 months ago
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reposted by
Johanna Joyce
9 months ago
American science is under attack Opinion piece by Dr Harold Varmus, Nobel Prize winner, former director of the
#NIH
and the
#NCI
🧪 “Perhaps what’s most disheartening is what feels like the absence of widespread opposition to this unraveling”
www.nytimes.com/2025/02/14/o...
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Opinion | American Science is Under Attack (Gift Article)
The Trump administration hobbles research and endangers the public health.
https://www.nytimes.com/2025/02/14/opinion/trump-public-health-funding-nih.html?unlocked_article_code=1.w04.ROib.mn-1HPm3aSr5
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reposted by
Veronica Rendo
10 months ago
So excited to see our paper describing the class of ARGOS genes in cancer out in
@naturecomms.bsky.social
! 🤩
www.nature.com/articles/s41...
A giant effort led with
@ms01.bsky.social
and executed under the mentorship of
@bendavidlab.bsky.social
@rameenberoukhim.bsky.social
@foijer-lab.bsky.social
🧵👇:
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A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer - Nature Communications
In cancer, the impact on cellular fitness of copy-number gains affecting collaterally-amplified genes remains poorly understood compared to oncogenes. Here, the authors integrate genomic data from tum...
https://nature.com/articles/s41467-025-56301-2
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Happy to share our new paper, published in
@emboreports.org
, in which we identify CDC20 as an important determinant of the cellular response to SAC inhibition. close collaboration with the
@foijer-lab.bsky.social
. Kudos to Linoy, Siqi and Lin for spearheading this study! 👏 Link in 1st comment 😊
10 months ago
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reposted by
Mcclelland lab
10 months ago
Abstract submission and registration date coming up soon at the end of Jan!
add a skeleton here at some point
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Great to see our joint study with
@stesantaguida.bsky.social
published in this month’s issue of Cancer Discovery:
aacrjournals.org/cancerdiscov...
With a super-kind Research Highlight written by Sam Bakhoum:
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Targeting RNA and Protein Turnover in Aneuploid Cancers
Summary:. Aneuploidy, an imbalance in chromosome number, is a hallmark of human cancers with chromosomal instability, and it remains a major therapeutic challenge. In this issue, Ippolito and colleagu...
https://aacrjournals.org/cancerdiscovery/article-abstract/14/12/2315/750133/Targeting-RNA-and-Protein-Turnover-in-Aneuploid?redirectedFrom=fulltext
11 months ago
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Join us in beautiful Stresa for this EMBO meeting, co-organized by
@mcclellandlab.bsky.social
,
@foijer-lab.bsky.social
,
@stesantaguida.bsky.social
, Daniele Fachinetti, Elsa Logarinho and myself.
add a skeleton here at some point
12 months ago
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