#InMemoriam: Dr. Robert Bruce Nicklas, who spent over 50 years unraveling the mysteries of how #chromosomes move during #CellDivision, died on February 19, 2025, at the age of 92. Leocadia Paliulis commemorates his life and work. rupress.org/jcb/article/...

'The Centre for Research in Cellular Biology of Montpellier (CRBM) is recruiting Junior/Senior Group Leaders to shape its research in the coming decade. The deadline for application is 31st of March 2026.' #sciencejobs focalplane.biologists.com/cell-biology...

Two new papers from the lab published in The EMBO Journal! link.springer.com/article/10.1... By Kai Walstein, @louisa-hill.bsky.social and others – On role of M18BP1 in CENP-A loading link.springer.com/article/10.1... By Arianna Esposito Verza and others – On mechanism of activation of PLK1

Mitosis lovers, get ready for Dubrovnik! 🔬🎉 I’m super excited to be organizing the 4th Mitotic Spindle Conference with Nenad Pavin, and we can’t wait to see you there! Want your abstract to be selected for a talk? Submit by Feb 8! www.phy.pmf.unizg.hr/~mitosis/ #SpindleCroatia2026

PhD position in my lab!

Mitosis has a timing system. If chromosomes attach properly, cells divide on schedule and keep proliferating. If attachment is slow or incomplete, the delay is recorded — and daughter cells stop dividing. We explore this link in our new preprint. 🔗 www.biorxiv.org/content/10.6...

Arianna Esposito Verza, @andrea-musacchio.bsky.social et al describe the long-sought-after mechanism of Bora dependency of PLK1 activation by Aurora A kinase during mitotic entry Another #RefereedPreprint ℅ @reviewcommons.org link.springer.com/article/10.1...

📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere. 🔗 Apply here 👉 recruitment.crg.eu/content/jobs...

The discovery of the first kinetochore proteins (CENP-A, CENP-B, CENP-C) was reported by Bill Earnshaw and Naomi Rothfield in 1985 in Chromosoma. Forty years later, Chromosoma/Chromosome Research has published a special issue (most articles are open access) link.springer.com/collections/...

We’re recruiting a Postdoctoral Researcher at OIST (Okinawa, Japan) to explore how mitotic stress shapes aging. If you’re excited about cell biology, aging, and mechanistic discovery, we’d love to hear from you. More info: www.oist.jp/careers/post... Website: www.oist.jp/research/res...

Our story on the kinetochore composition of the ciliate Tetrahymena thermophila is out now on bioRxiv! We find surprisingly many orthologs of conventional kinetochore components, but also components that have very different evolutionary origins. A 🧵 (1/11) Check it out here: tinyurl.com/4ectm9x4

Alves Domingos, Green, Cheerambathur et al. reveal that the #kinetochore protein KNL-1 regulates the #actin #cytoskeleton to control dendrite branching. rupress.org/jcb/article/... 📕 In Cellular Neurobiology collection: rupress.org/jcb/collecti... #SfN25

Interested in pursuing a PhD by working on a long-neglected marine organism and making a lot of discoveries? Darwin Trust offers a PhD studentship for international students (anyone non-UK) www.findaphd.com/phds/project...

Cryptococcus neoformans employs both PP1 and PP2A phosphatases to silence the spindle checkpoint https://www.biorxiv.org/content/10.1101/2025.11.04.686612v1

My team is recruiting a Study Engineer (IE) with experience in mammalian cell culture - ideally human iPSCs - to work on a project exploring the role of aneuploidy and centromere regulation in neuroblastoma initiation and progression. info and application here institut-curie.org/job/study-en....

📣 We are moving to Barcelona to join the amazing @crg.eu and explore how centrosomes & cilia work, evolve & respond to the environment. We are looking for PhD students www.crg.eu/en/content/t... Postdocs gimm.pt/jobs/postdoc... Other calls to open, also for an experienced lab manager. Get in touch!

1 week left to apply for PhD studentships with @cruk-cityoflondon.bsky.social. Great projects are on offer- including from our lab @qmbci.bsky.social developing new strategies to target the cell cycle as a cancer therapy Project: www.colcc.ac.uk/2026-blic-ph... Apply: www.colcc.ac.uk/black-leader...

Interactions with the nucleosome’s acidic patch and DNA entry/exit site give the chromosomal passenger complex CPC a non-catalytic role in stabilizing #centromeric chromatin #cryoEM and biochemical, cellular data by AA Jeyaprakash and coworkers www.embopress.org/doi/full/10....

I have a PhD opening in my lab for an exiting project using base editor screens to find novel drug targets. Please help spread the word. candidate.hr-manager.net/ApplicationI...

Our latest research in collaboration with @nilssonlab.bsky.social, @andrea-musacchio.bsky.social and Mathieu Bollen reveals a new regulatory strategy employed by cells to control PP1 in mitosis. Check it out in @currentbiology.bsky.social www.sciencedirect.com/science/arti...

Now out in Science! Cyclin-dependent kinases (CDKs) are key regulators of the cell cycle. In @vcushing.bsky.social's magnum opus, we use #cryoEM to figure out how the CDK-activating kinase recognises CDKs to fully activate them - a key step in cell cycle control. www.science.org/doi/10.1126/...

We’re thrilled to announce this workshop! 🌟 Are you a junior PI in the process of building your lab? Join us in Regensburg for an inspiring workshop where we’ll exchange ideas and strategies on how to develop a motivated and harmonious team. 👉 Check it out! There are sponsored spots available!

Perspective from Richard McIntosh describing the history of research on #microtubule polymerization in terms of the ideas, technologies, and observations that have emerged as countless researchers have studied the dynamics of these essential cytoskeletal polymers. rupress.org/jcb/article/...

Are you a future black leader in cancer? Come join @mirazrahman.bsky.social and my labs @qmbci.bsky.social @kingscollegelondon.bsky.social to work on turning defective cell cycle checkpoints into innovative cancer therapies! Get in touch for more details www.colcc.ac.uk/2026-blic-ph...

We are looking for our next PhD student to join us 🤩 www.mcclellandlab.com to understand cancer radiation therapy's impact on DNA damage repair and chromosomal instability. Prestigious funding from CRUK RadNet. Please contact me informally - deadline 5th Nov! crukradnet.colcc.ac.uk/phd-students...

Good things still happen: a couple of weeks ago Nelson Leça successfully defended his PhD! 🥳 He did a fantastic job discussing his work and "wrestling" the exciting examination led by @jakedel.bsky.social and @pseudoenzyme.bsky.social. It was a good day! 👏🎉

Very excited to post our latest work showing the mitotic stopwatch monitors more than just mitotic delays - it protects against whole genome doubling and cell enlargement. Great work by fantastic postdocs Lindsey and Reece (& student Maria) #PostdocAppreciationWeek www.biorxiv.org/content/10.1...

Happy to share our work in @embojournal 👉 shorturl.at/zXNyn For decades, we’ve known cells dismantle & rebuild the nuclear envelope in sync with spindle poles. But why does this coordination matter? And how do pole material properties ensure error-free division? Follow this thread to know more 👇

Fantastic seminar by Jake @jakedel.bsky.social on the wonders of the NDC80 complex, which never ceases to amaze.

Our group [@i3suporto.bsky.social] is hiring a Senior Technician (tinyurl.com/3ehju86r) and a Bioinformatician (tinyurl.com/2xwatnpx). Know someone who might be a good fit? Send them our way

Looking for your next step in fly genetics? The Rajan Lab at Fred Hutch is hiring a staff scientist + postdoc for projects on fat–brain signals, immunity, and brain aging. Stable, long-term role in a collaborative lab. Apply: careers-fhcrc.icims.com/jobs/30062/j...

New cell cycle meeting starts next summer! events.faseb.org/event/c40174...

The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona | Science Advances www.science.org/doi/10.1126/... Congratulations @vcmentowski.bsky.social for solving a remarkably challenging molecular puzzle

Measuring chromosomal instability #CIN isn’t straightforward. We compared live imaging, FISH, scDNA-seq & other assays, and found significant differences. Our take: Use mis-segregations per diploid division (MDD) as a clear standard. www.pnas.org/doi/10.1073/...

Great seminar by Viji @viji-draviam.bsky.social at @i3suporto.bsky.social and very insightful discussions. Always a pleasure to host colleagues and brainstorm!

🚨🚨🚨 Please repost We are looking for postdocs to join our lab at NIH. Apply: www.nichd.nih.gov/research/atNICHD/Investigators/rocha/apply Learn more about training at NIH : www.training.nih.gov/research-tra...

#1 Centromeres are epigenetic loci defined by CENP-A, positioned in unmethylated DNA flanked by highly methylated regions. Our work, published in @natgenet.nature.com in collaboration with @naltemose.bsky.social investigates the role of DNAme at human centromeres www.nature.com/articles/s41...

New preprint from the lab! Please check it out. 🚨 Have you ever wondered how cells decide when it’s time to divide? So did we! www.biorxiv.org/content/10.1...

Abouelghar, Carrier, @mpmiller.bsky.social et al. @utah.edu show that budding yeast Stu2’s #kinetochore function is essential for cell viability. Surprisingly, this function is independent of its canonical ability to induce #microtubule assembly and disassembly. rupress.org/jcb/article/...

Check out our new manuscript on biorxiv on the role of MOS in mammalian oocyte meiosis: www.biorxiv.org/cgi/content/... With @schindlerlab.bsky.social @giselacairobaza.bsky.social @muhammad-haseeb.bsky.social

Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1... Soon at @spirochrome.com Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social

My department at Dartmouth Medical School is hiring a tenure-track Assistant Professor. We are looking broadly for a biochemist or cell biologist. Please share this add! apply.interfolio.com/171438 @dartmouthbcb.bsky.social @futurepislack.bsky.social

@currentbiology.bsky.social has always been one of my favorite journals but I think they have now outdone themselves www.cell.com/current-biol.... And picked up by the @nytimes.com as well! www.nytimes.com/2025/08/18/s...

Final call: Applications close September 2! KI is recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential. All positions: ki.se/en/about-ki/...

FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...

Narozna et al @gorbskylab.bsky.social uncover a high-frequency, chromosome 12-specific mis-segregation error in iPSCs. Eroded 12p arms lead to bridging & micronucleation, enabling widespread trisomy 12. A slight growth advantage allows trisomic cells to persist & dominate rupress.org/jcb/article/...

Are you curious about what PLK1 kinase is up to these days? Have a look at our latest review on @cp-trendscellbio.bsky.social. Arianna Esposito Verza, @andrea-musacchio.bsky.social and I discuss the latest findings on a very important enzyme that is still full of surprises, 35+ years from discovery!