Our previously preprinted study "Influence of cis-regulatory elements on expression divergence in human segmental duplications" is now published in @genomeresearch.bsky.social! Please check it out: genome.cshlp.org/content/earl...

Summarizing Davis youth soccer drama from Nextdoor as a comic adaptation is a totally justified use of ChatGPT (and my evening) ⚽

Both a lion and a bear spotted this week... it’s getting wild in Davis! #OhMy 🦁🐻🐾

Introducing our third set of invited speakers at #ZDM19! Please join Rashmi Priya, Paul Riley, Caroline Wee & the rest of the #ZDMS community in Oxford 🐟 We hope to see you there! Don't forget to submit an abstract! Extended deadline ends May 15th ⌛ To submit: www.zdmsociety.org/zdm19-abstra... ✨

Happy AAPI month and belated Mother's Day to all the second generation tiger moms doing the work figuring out which parts to carry forward versus leave behind. I know it's a trip, but so so worth it.

Don't miss the ASHG annual meeting abstract submission deadline, just one week away! This year's meeting will be held in Montreal, October 20–24. The deadline is earlier than in previous years, so be sure to submit and share your research: ashgmeeting.ashg.org/programs/abs... #ASHG26 #ASHG2026

Science advocacy in action! 🧬 ASHG Board members met w/ lawmakers on Capitol Hill to push for $51.303B NIH base budget + key policies impacting research. With proposed cuts to NIH/NSF/ARPA-H, you can add your voice from your state: complete the ASHG Action Alert 👉 https://bit.ly/4u9YrBe

On the Hill with @geneticssociety.bsky.social advocating for NIH funding. 🧬 Genetics research drives better diagnoses & treatments, trains the next generation of scientists, and keeps the U.S. competitive in biomedical innovation. Thanks to the lawmakers who engaged with us today! 🇺🇸

The special issue Functional and Adaptive Effects of Genomic Structural Variation is now out in Heredity. Many thanks to all contributors for their submissions, to the editorial team at @heredityjournal.bsky.social and to @ellenleffler.bsky.social, @mydennis.bsky.social & @gokcumenlab.bsky.social!

Diedre Reitz ( @diedrereitz.bsky.social ), PhD, a Postdoctoral Fellow in the Department of Microbiology and Molecular Genetics at UC Davis, will be giving a seminar on Monday, March 23rd at 4:00pm in Kollros Auditorium. We hope to see you there!

Everyone could use a little purple cat in their life - happy Thursday from my 5yo 🐾

Whoa! Looking forward to checking this one out

I had a blast working on this paper! This was the first mammalian assembly paper using the new CiFi tech, and we combined multiple lines of evidence to verify a prairie-vole-specific duplication of Avpr1a. All methods will be open source and reproducible, enabling the community to build on them.

Excited so share our newest study using a single-library HiFi-CiFi approach to generate chromosome-scale diploid assemblies of two vole genomes, identifying putative drivers of divergent pair-bonding behavior, namely a prairie-vole-specific duplication of Avpr1a gene, led by @mabuelanin.bsky.social

BenchDrop-seq: a microfluidics-free platform for benchtop single-cell long-read RNA sequencing https://www.biorxiv.org/content/10.64898/2026.03.12.706999v1

parents in davis this morning waiting for summer camp registration to open

GENETICS: @mydennis.bsky.social from University of California Davis discussed the querying complex genomic regions important in human disease and evolution at the 2026 AGBT General Meeting. #AGBTGM26

JAX Long-Read Sequencing Workshop Keynotes by @aphillippy.bsky.social & @mydennis.bsky.social Co-organized by @olgaanczukow.bsky.social, @christinebeck.bsky.social & Mark Adams ✈️ Trainee travel awards 📝 Abstracts due March 3 🥼 Optional wet-lab training session 🔗 www.jax.org/education-an...

Please check out these amazing women! They are fantastic scientists, committed mentors, supportive friends and honestly super stars! 🤩@bradylabs.bsky.social @mydennis.bsky.social @ucdavis.bsky.social www.ucdavis.edu/news/podcast...

Anyone in the U.S. got an ERK biosensor zebrafish line they'd be willing to share/ship to VA? vascular specific would be preferred, but I'll take global too. @zebrafishrock.bsky.social

Recently learned that I will be promoted to FULL PROFESSOR(!) this coming summer. So happy and thankful for those that have supported me along the way, including collaborators, mentors, colleagues, friends, family, trainees, and letter writers. #bighugs #youdabest #firstgen

Please repost and share widely - winter break is a perfect time to assemble application materials 😅

Did you know the last common ancestor of #zebrafish and humans was ~450 million years ago? A whole genome duplication event (3R) occurred early in the teleost fish phylogeny. Despite this event, zebrafish and humans have about the same number of chromosomes. #ZebrafishFunFacts 🧪

Absolutely thrilled to share the latest work from my lab focused on the variation and evolution of human centromeres among global populations! We assembled 2,110 human centromeres, identifying 226 new major haplotypes and 1,870 α-satellite HOR variants. www.biorxiv.org/content/10.6...

CiFi: accurate long-read chromosome conformation capture with low-input requirements. #HiFi #LongRead #Sequencing @natcomms.nature.com 🧪🧬 🖥️ www.nature.com/articles/s41...

Consider applying for the Robert E. Chason Endowed Chair in Translational Research at the UC Davis MIND Institute! Join a vibrant community of colleagues studying neurodevelopment conditions like autism. UC Davis is an excellent place to work and live. Find more details here: lnkd.in/gZRyViNa

Excited to share our final accepted version of the CiFi method out today: www.nature.com/articles/s41...

Lab ice skating and winter party ❄️⛄️

Very happy to share that I’ve been awarded a K99 Career Development Award from NIGMS for my work on MSH2-MSH6 and its role in recombination-mediated rearrangements. Big thanks to my mentor, Wolf Heyer, co-mentor, Megan Dennis, letter writers, and colleagues. mmg.ucdavis.edu/news/two-mmg...

Join us at this exciting Workshop on #LongReads with keynotes from @aphillippy.bsky.social @mydennis.bsky.social co-organized by @christinebeck.bsky.social and Mark Adams @jacksonlab.bsky.social Register www.jax.org/longread #RNA #genomics #bioinformatics #cancer #medicine #evolution #neuroscience

The lab is coming out strong with their "fishman" pumpkin-contest submission this year for the Halloween Symposium today @ucdgenomecenter.bsky.social ! Pumpkin credit: @nicholashaghani.bsky.social 👻🎃

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Excellent review from @silparacchini.bsky.social’s lab with a nice bluetorial

Happy to share a new @biorxivpreprint.bsky.social from the lab, led by talented postdoctoral fellow #MinhooKim: "Single-cell exploration of ovarian aging across vertebrate models", a meta-analysis study of public ovarian aging sc/snRNA-seq data! www.biorxiv.org/content/10.1... A 🧵, 1/5 🧬🖥️🧪 #GeroSky

We are thrilled to share our new preprint entitled “The origin and molecular evolution of the mammalian liver cell architecture” www.biorxiv.org/content/10.1...

Happy to share work spearheaded by former grad student Colin Shew testing shared duplicated cis regulatory elements (CREs) using an MPRA. While we find some high effect CREs, collectively paralog differences represent modest effects accounting for observed gene expression divergence.

🔁 Please share - we remind the SMBE community that the Call for Symposia for SMBE2026 in Copenhagen is open. We invite you to submit a symposium proposal to help shape the scientific content of our annual meeting. 🗓️ Deadline: October 15th More information: smbe2026.org/symposia #SMBE2026

Really cool, conceptually simple approach here: cross-referencing grant proposal scores with literature citations and explicit acknowledgments in drug patents to identify patents linked to projects that wouldn't have been funded given a smaller budget

While I'm sad our cover submission wasn't selected for our recent human duplication paper, check out the super cool illustration created with @lazaroillustration.bsky.social ! Certainly, you will be seeing Dennis lab members running around with "fishman" t-shirts at future meetings, inspired by Ohno

Lab outing 😍

Excited to share our recent study on human-specific features of the cerebellum and the unexpected, novel role of zona pellucida protein 2 (ZP2) in synapse development. Grateful to the Sestan lab and all our collaborators for their outstanding contributions. www.biorxiv.org/content/10.1...

New preprint alert! The uterus expands ~500-fold in pregnancy, yet we know little about how pressures are sensed. Led by @yunxiao-dr.bsky.social, we show PIEZOs are required for contractions and birth in mice, with dual roles of PIEZO1 in muscle and PIEZO2 in neurons www.biorxiv.org/content/10.1...

Jasmin Rees PhD chapter as a paper just out at the AJHG @ajhgnews.bsky.social, with Sergi Castellano, who first envisioned the study. Jas investigated signatures of human local genetic adaptation in hundreds of micronutrient-associated genes.

Privileged to have had the opportunity to advocate for biomedical research funding in #Congress yesterday! It was an honor to represent the @geneticssociety.bsky.social alongside my amazing colleagues @gregorylab.bskyverified.social and #JillFahrner! 🔬 🧠🧬 #ASHG #Genetics #ResearchMatters

A recent paper reveals a surprising insight. The length of the cell cycle in a particular tissue determines the oncogenic transformation capacity of particular oncogenes, with tissues with shorter cell cycles most susceptible 3/n

Happy Birthday, Rosalind Franklin. She captured an X-ray diffraction image of DNA and stated that a helical structure was probable. Watson and Crick then created a detailed model based on her results. They initially received credit for the discovery and were awarded the Nobel Prize after her death.🧪

In work led by @lalli.bsky.social, we present recombination maps and a diverse haplotype reference panel (1000 Genomes Project) for the T2T-CHM13 human reference genome. These resources improve the accuracy of phasing and imputation, especially around common CNVs. www.biorxiv.org/content/10.1...

Evolutionary molecular biology paying dividends again - this time in finding new modulators of innate immunity - www.science.org/doi/10.1126/...

So excited to see this paper out in Cell from the group of my good friend @mydennis.bsky.social It's been so exciting to see this story progress progress. www.cell.com/cell/abstrac...