From AI-powered research to unlocking gene function, JAX scientists are paving the way for the future of precision medicine. Here is some notable news you may have missed. https://www.jax.org/news-and-insights/2025/december/jax-research-roundup-virtual-hearts-flu-therapy-and-more

✨ Did you know JAX offers free, self‑paced online MicroLessons (15 minutes) and Mini‑Courses (1–2 hours)? 👉 MicroLessons: https://education.learning.jax.org/page/online-microlessons 👉 Mini‑Courses: https://education.learning.jax.org/page/online-minicourses

We know it's New Years Eve, but these aren't fireworks 🎇! Check out this microscopy image of neural progenitor cells — multipotent, self-renewing cells in the central nervous system that generate neurons and glial cells in the 🧠. Credit: Pera Lab at JAX

New year, new era of discovery. Thank you for all of your support this year and we can’t wait to share 2026 with you. Happy New Year from all of us at The Jackson Laboratory!

We're sharing some of our most popular posts of 2025. JAX developed mouse models that survive premature death and enable pre-clinical testing of #AHC. https://www.jax.org/news-and-insights/2025/july/mouse-models-for-ultra-rare-disorder-could-pave-the-way-for-nervous-system-gene-editing-therapies

As we head into 2026, we're sharing some of our most popular posts of 2025. This video from our JAX in Motion series linking the Microbiome & ME/ Chronic Fatigue Syndrome was our most popular video of the year on social media! https://youtu.be/lV9OsLvWWL0

As we head into 2026, we're sharing some of our most popular posts of 2025. This featured image taken at JAX of was our most popular image of the year on social media. It shows a single-cell spatial transcriptomic map of the human endometrium (the inner lining of the uterus). 🔬

This new featured image from JAX shows a 3D rendering revealing the intricate interior of a human stem cell, centered around a prominent blue nucleus. 🔬 🧪 Learn more: https://www.jax.org/news-and-insights/2025/december/understanding-the-structure-of-a-stem-cell

#CARDIOVERSE: Combining AI, stem cells & genetic variation to predict drug safety before human trials. By building virtual hearts, JAX scientists aim to dramatically reduce the need for large-animal studies, streamline approvals & ensure safer, faster delivery to patients. go.jax.org/cardioverse

At a packed event in Manhattan, we officially "tied the ribbon" with JAX and NYSCF officials, local politicians, and supporters came together to celebrate the symbolic joining of our two organizations — and the start of a new era in biomedical discovery. https://youtu.be/tKw9bACnP0w

Developing new drugs is one of the riskiest and most expensive endeavors in science, but a new project led by The Jackson Laboratory aims to change that. JAX's new CARDIOVERSE project combines AI, stem cells, and genetic variation to predict drug safety before human trials. 🧪 go.jax.org/cardioverse

The EndoRISE Fall Forum, hosted by JAX, spotlighted groundbreaking science, patient-centered solutions, and the power of partnership to transform outcomes for millions living with endometriosis. 📰 Read the story: https://go.jax.org/ERForum2025 📼 View clips from the event in the comments ⤵️

Rewiring Recovery: How researchers at JAX are studying exactly how the brain’s neural circuits change after a stroke—and the effects that has on #stroke survivors. 🧠 🧪

Gretchen Clark, 2025 JAX Scholar, is exploring how circadian rhythms influence cellular aging—especially the behavior of senescent cells. Her work could unlock new strategies for healthy aging. Watch her explain the science in this one-minute video: https://youtu.be/oq8lxhudOnE?si=Nd7G235lBtTQ-UeL

Thanks to an up to $30M contract award from ARPA-H, JAX aims to revolutionize drug safety testing with the #CARDIOVERSE—a new project that combines #AI, #stemcells, and #genetic variation to predict #drugsafety before human trials. 💊 🧪 🔬 🤖 go.jax.org/cardioverse

Together, JAX and NYSCF combine strengths in genetics, stem cells and data science to accelerate discovery and deliver solutions that will make a lasting difference for patients around the world. 🧬 🐁 🔬

🧬 Curious about the difference between #genetics and #epigenetics? Explore how environment, epigenetics and health intersect with @jacksonlab.bsky.social's free, 1 – 2 hour course: education.learning.jax.org/beyond-genes... #EpiSci #EpigeneticsSci #Epigenomics

Reprogramming biology: iPSCs and the future of predictive research How patient-derived stem cells and genomic tools are transforming disease modeling and accelerating cures 🧬🧪🔬🧫

We are grateful for the incredible people who make our mission possible. From the patients and families who inspire us, to the researchers, partners and supporters who fuel discovery, thank you for being part of the JAX community. Together, we're advancing science and improving human health.

Dive into our latest issue of JAX's Search Magazine to read all about the JAX-NYSCF Collaborative and how we're building an integrated discovery platform with #mice, #stemcells, and #AI to transform human health. 🧠 🧪 🔬 🤖 https://online.flippingbook.com/view/661118668/

Reprogramming biology: iPSCs and the future of predictive research How patient-derived stem cells and genomic tools are transforming disease modeling and accelerating cures 🧬🧪🔬🧫

As winter approaches, we’re reflecting on the incredible work happening at JAX. Thank you, Commissioner Michael Duguay of the Maine Department of Economic and Community Development, for visiting this week to learn about our work and the impact of state support on our mission to improve human health.

Mice pups conceived with #IVF in the lab have slightly increased rates of DNA mutations, compared to pups conceived naturally, a new study suggests. 🧬🧪 The results do not directly apply to humans, but highlight the importance of understanding how fertility treatments affect an offspring’s DNA.

What does it take to turn a bold idea into a life-changing treatment? At JAX, innovation is more than progress — it’s the power to transform lives.

Curious how cutting-edge research is advancing #RareDisease treatment? 🧬 Explore the biology and genetics of rare disease, work through case studies and learn how preclinical research drives therapeutic development in @jacksonlab.bsky.social's 🆓 course: education.learning.jax.org/exploring-ra...

The brain is over 50% lipid—but this vital component remains a mystery. JAX scientist Kristen O’Connell uses high-res mass spectrometry to study how these molecules support memory and cognition—and what happens when they don’t. 🧠 go.jax.org/OConnell

Great stuff from @jacobtlevy.bsky.social & Kristen. If you want to learn even more about Kristen & her work, we've got you covered! 5 Minute Genius™ talk: youtu.be/vnZ7zODxFVk?.... And learn more about Kristen on our Maine Science Podcast episode! maine-science-podcast.simplecast.com/episodes/kri...

Join us at this exciting Workshop on #LongReads with keynotes from @aphillippy.bsky.social @mydennis.bsky.social co-organized by @christinebeck.bsky.social and Mark Adams @jacksonlab.bsky.social Register www.jax.org/longread #RNA #genomics #bioinformatics #cancer #medicine #evolution #neuroscience

Heading to #SfN25? Don’t miss "Navigating Stem Cell Resources" for a brief intro to stem cell repositories, key models and tools. Presented with @jacksonlab.bsky.social and @simonsfoundation.org#SfN25 🗓️ 11/17, 2–3 PM 📍 Room 4 📲 Add to itinerary: https://www.abstractsonline.com/pp8/#!/21171/session/1426

Reprogramming biology: iPSCs and the future of predictive research How patient-derived stem cells and genomic tools are transforming disease modeling and accelerating cures 🧬🧪🔬🧫

In his own words, JAX President & CEO Lon Cardon reflects on how the JAX-NYSCF partnership brings together people, ideas and innovation to accelerate discoveries and improve human health. 🧬 https://www.jax.org/news-and-insights/2025/october/the-power-of-3

The brain is over 50% lipid—but this vital component remains a mystery. JAX scientist Kristen O’Connell uses high-res mass spectrometry to study how these molecules support memory and cognition—and what happens when they don’t. 🧠 go.jax.org/OConnell

Biomarker testing + the expertise to interpret results are essential to precision cancer care. MCGI & @jaxeducation.bsky.social are closing the gap to precision oncology. Get the details: https://go.jax.org/connectingthedots #CancerBiomarkerDay #GeneticCounselorAppreciationDay 💙

We sat down with Daniel Paull, JAX's new VP of discovery and platform development, to talk about the JAX-NYSCF Collaborative, the importance of induced pluripotent stem cells, the future of precision medicine, and more. 🧬 🔬 https://go.jax.org/Paull5Q

The brain is over 50% lipid—but this vital component remains a mystery. JAX scientist Kristen O’Connell uses high-res mass spectrometry to study how these molecules support memory and cognition—and what happens when they don’t. 🧠 go.jax.org/OConnell

From cells to mice to AI-powered insights — JAX is building better models for faster, smarter discoveries. JAX researchers at the forefront of advances in stem cells and cell modeling. 🧬🤖

In his own words, JAX President & CEO Lon Cardon reflects on how the JAX-NYSCF partnership brings together people, ideas and innovation to accelerate discoveries and improve human health. 🧬 https://www.jax.org/news-and-insights/2025/october/the-power-of-3

From rare diseases to cancer care, genomics is already transforming medicine. @jaxeducation.bsky.social and the University of New England are training future clinicians to apply genomic science to real-world care — before they even enter medical school. 🎓 🧬

🧠 November is #NationalAlzheimersDiseaseMonth, recognizing those working to better understand, support and care for people affected by #Alzheimers. 60+ researchers joined @jacksonlab.bsky.social workshops in 2025 to strengthen the community working to #EndALZ: www.jax.org/news-and-ins...

The brain is over 50% lipid—but this vital component remains a mystery. JAX scientist Kristen O’Connell uses high-res mass spectrometry to study how these molecules support memory and cognition—and what happens when they don’t. 🧠 go.jax.org/OConnell

We sat down with Daniel Paull, JAX's new VP of discovery and platform development, to talk about the JAX-NYSCF Collaborative, the importance of induced pluripotent stem cells, the future of precision medicine, and more. 🧬 🔬 https://go.jax.org/Paull5Q

In his own words, JAX President & CEO Lon Cardon reflects on how the JAX-NYSCF partnership brings together people, ideas and innovation to accelerate discoveries and improve human health. 🧬 https://www.jax.org/news-and-insights/2025/october/the-power-of-3

🧬 🖥️ Tackling genomic data can feel overwhelming. Building confidence starts with the basics. Explore @jacksonlab.bsky.social’s Beginner’s Guide to Genomic Databases to strengthen your skills in genomic data structures, annotation and sequence alignment: education.learning.jax.org/genomic-data...

🎉 The 9th Annual JAX Scientific Symposium brought together @jacksonlab.bsky.social’s trainees and faculty to share groundbreaking research and innovative ideas. Join us in celebrating our top awardees ⬇️

We sat down with Daniel Paull, JAX's new VP of discovery and platform development, to talk about the JAX-NYSCF Collaborative, the importance of induced pluripotent stem cells, the future of precision medicine, and more. 🧬 🔬 https://go.jax.org/Paull5Q

We sat down with Daniel Paull, JAX's new VP of discovery and platform development, to talk about the JAX-NYSCF Collaborative, the importance of induced pluripotent stem cells, the future of precision medicine, and more. 🧬 🔬 https://go.jax.org/Paull5Q

In his own words, JAX President & CEO Lon Cardon reflects on how the JAX-NYSCF partnership brings together people, ideas and innovation to accelerate discoveries and improve human health. 🧬 https://www.jax.org/news-and-insights/2025/october/the-power-of-3

The bold new alliance between JAX and NSYCF promises to transform biomedical research and bring life-changing therapies to patients faster than ever before. 🧬 🧪 🔬 Learn more: www.jax.org/news-and-insights/2025/october/scope-speed-scale-

“From the laboratory bench to the executive suite” — powerful insights on leadership, resilience, and purpose from Joanne Berger-Sweeney at the Hewett Family Lecture. Congratulations to our Hewett Leadership graduates, and thank you for continuing to inspire the future of nonprofit leadership.

Together, we’re redefining what’s possible.​ ​ With the acquisition of the New York Stem Cell Foundation, The Jackson Laboratory is connecting the power of mouse, cell, and AI models to speed breakthroughs from discovery to therapy and transform the future of medicine.​