Darren Obbard
@darrenobbard.bsky.social
π€ 1656
π₯ 664
π 205
Flies, Viruses, Genomes
pinned post!
Hi everyone! Please re-post: I want to highlight the amazing work of
@queendroso.bsky.social
and a newly formed NGO called the "Blossom STEM Education Initiative (BloSTEMEI)", which aims to support
#STEM
#Education
,
#Mentorship
, innovation, and research-driven
#ScienceOutreach
across Africa ..
4 days ago
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Hi everyone! Please re-post: I want to highlight the amazing work of
@queendroso.bsky.social
and a newly formed NGO called the "Blossom STEM Education Initiative (BloSTEMEI)", which aims to support
#STEM
#Education
,
#Mentorship
, innovation, and research-driven
#ScienceOutreach
across Africa ..
4 days ago
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Darren Obbard
bioRxiv Evolutionary Biology
10 days ago
Balanced polymorphism in a floral transcription factor underlies an ancient rhythm of daily sex alternation in avocado
https://www.biorxiv.org/content/10.64898/2025.12.22.695989v1
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Margot Finn
15 days ago
14 two-year postdocs for academics of any nationality who cannot continue their research due to US politics. Do share if you know of such.
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Love this!
www.biorxiv.org/content/10.1...
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Meiotic double strand DNA breaks and spontaneous mutation in Drosophila melanogaster
The exchange of genetic material during meiosis requires the formation and repair of DNA double-strand breaks (DSBs), which may not be repaired with perfect fidelity. If meiotic exchange is mutagenic,...
https://www.biorxiv.org/content/10.1101/2025.10.29.685400v1
15 days ago
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David Enard
19 days ago
1/3) PhD student Mary Reed Weston analyzed virus-driven human adaptation across the viral replication cycle based on ~8,000 annotated proviral and antiviral effects manually curated from the virology literature. The steps of entry and release clearly stand out:
www.biorxiv.org/content/10.6...
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15 days ago
π£Excited to share our (first) VirJenDB publication! πCheck it out to see how your
#virus
database supports
#metadata
#biocuration
and
#bioinformatics
integration. πΆStay tuned for collaboration opportunities in 2026, including a hackathon at
#ViBioM2026
! π
doi.org/10.1093/nar/..
. π»
www.virjendb.org
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Dr Alison Peel
19 days ago
π¦ Two PhD positions available on our new ARC Discovery Grant: "From Diversity to Disease: Viral Ecology, Evolution and Persistence in Bats" The project will investigate how viral diversity evolves and persists, with a particular focus on recently discovered henipaviruses in Australian flying foxes.
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Matt Bertone
29 days ago
Very cool tool. Apparently I have the first observation on iNaturalist for 11 taxa! Some are rare, others I got to first. However, I wonder how in flux these will be if people add historical observations later π€ Regardless it's neat! π
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Comparative genomics of the Testacea group of Drosophila reveals introgression and variation in chromosome size and structure
Abstract. Comparative genomic analyses among closely related species provide an opportunity to assess their evolutionary history. The relatedness between s
https://academic.oup.com/gbe/advance-article/doi/10.1093/gbe/evaf225/8362500
29 days ago
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mara lawniczak
about 1 month ago
a life changing opportunity made possible by the Nobel Prize funds awarded to John Sulston -- the
@sangerinstitute.bsky.social
runs the Sanger Prize scheme, open to an undergrad from any LMIC to spend 3 months here learning all about genomics. more details here
www.sanger.ac.uk/about/study/...
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#RNAi
#Drosophila
#Testis
#Evolution
www.biorxiv.org/content/10.1...
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Recurrent expansion and rapid evolution of the Drosophilid RNAi pathway in testis
Multiple classes of selfish genetic elements, including transposable elements, meiotic drivers, and viruses, are suppressed by small interfering RNAs (siRNAs) that guide RNA interference (RNAi). These...
https://www.biorxiv.org/content/10.1101/2025.11.28.691189v1
about 1 month ago
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Marc Robinson-Rechavi
about 1 month ago
I'm excited to present this new model to detect positive selection on regulatory sequences, which has been 3 years in the making! Thanks to Alexandre LaverrΓ© and @Phylogenetrips for their amazing work on this project. π https://doi.org/10.1101/2025.11.26.690685
#bioinformatics
#MolecularEvolution
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mara lawniczak
about 1 month ago
job details here
sanger.wd103.myworkdayjobs.com/en-GB/Wellco...
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The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution - Nature
The Biodiversity Cell Atlas aims to create comprehensive single-cell molecular atlases across the eukaryotic tree of life, which will be phylogenetically informed, rely on high-quality genomes and use...
https://www.nature.com/articles/s41586-025-09312-4
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Marco Incarbone
about 1 month ago
Preprint alert! It is my great pleasure to announce the first manuscript from the lab, a story that started
@gmivienna.bsky.social
and was mainly accomplished by the intrepid
@gesahoffmann.bsky.social
at
@mpi-mp-potsdam.bsky.social
. A brief thread with our findings
www.biorxiv.org/content/10.1...
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AGO5 restricts virus vertical transmission in plant gametophytes
The propagation of a viral infection from a host parent to its progeny is known as vertical transmission, or seed transmission in plants. It allows viral infections to rapidly spread locally via polle...
https://www.biorxiv.org/content/10.1101/2025.11.28.691182v1
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Mark A. Hanson
about 1 month ago
Paper for the
#Drosophila
community on a food recipe that rears dozens of species. This was a full team effort, with key contributions from UG, MSc, and PhD students! π©βππ Plus an
#infection
observation re: Diet x
#Microbiota
π¦
www.biorxiv.org/content/10.1...
#EvolBiol
#AcademicSky
#SymbioSky
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Robert J. Gifford
about 1 month ago
"The hyperreal bat: more vivid, more coherent, and more narratively satisfying than any bat in nature." Why does the idea of bats as special viral reservoirs endure? New Substack post:
robertjgifford.substack.com/p/bats-and-v...
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Bats and Viruses: Rumour, Intrigue, Deception, and Spectacle
Bats as Hyperreal Reservoirs of Viral Disease
https://robertjgifford.substack.com/p/bats-and-viruses-rumour-intrigue
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fly paper broadcast
about 1 month ago
Constrained reassortment and genotype-specific traits shape the evolutionary landscape of galbut virus
#Drosophila
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Constrained reassortment and genotype-specific traits shape the evolutionary landscape of galbut virus #Drosophila
PubMed link
https://pubmed.ncbi.nlm.nih.gov/41287636/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1tih1KzP2IVszyspVOiUrPn-jnW1Q1Ryj5vJBQtngFA-7oVYAA&fc=20250213113502&ff=20251125062352&v=2.18.0.post22+67771e2
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#Drosophila
#Phd
opportunity in
#PopGen
and
#Ecology
with Jan Hrek
lab.hrcek.net/PhD_Rapid_Ev...
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http://lab.hrcek.net/PhD_Rapid_Evolution_in_Communities_2025.pdf
about 1 month ago
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Love this! (Thanks to
@blongdon.bsky.social
for altering me!)
www.biorxiv.org/content/10.1...
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Experimental infections reveal unexceptional viral tolerance in bats
Bats are a conspicuous source of zoonotic viruses with pandemic potential. A common explanation for bats being βspecialβ viral reservoirs is their ability to coexist with viruses without suffering ove...
https://www.biorxiv.org/content/10.1101/2025.08.28.672855v1
about 1 month ago
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GBIF
about 1 month ago
Register for our next GBIF #DataUseClub πβοΈ Hear about the research of the 2025 GBIF Graduate Researcher's Award winners - PhD student Kumdet Panshak Solomon (#Nigeria) and Master's student Esteban Marentes Herrera (#Colombia)! π 11 December 2025, 15:00-16:30 CET π
gbif.link/DUC_GRA
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The University of Edinburgh's Science Magazine
about 2 months ago
β¨ A huge thank you to everyone who joined us! π» Special shout-out to our featured scientists: πͺ²
@persmiseth.bsky.social
, Lecturer in Animal Behaviour πͺ°
@darrenobbard.bsky.social
, Professor of Evoluntionary Genetics π¦ Simon Martin, Royal Society University Research Fellow
#ScienceCommunication
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Darren Obbard
Fly School
about 2 months ago
Excited to announce that Fly School IV will be 27 July-9 August 2026, in Costa Rica! Applications will open in January.
@dipterists.bsky.social
@flygirlnhm.bsky.social
@bertonemyia.bsky.social
@teamdiptera.bsky.social
@entcollnet.bsky.social
@dipteristsforum.bsky.social
@entsocamerica.bsky.social
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Zamin Iqbal
about 2 months ago
Honoured and quite blown-over to receive this award. I have been, and continue to be, very lucky - first with great mentors, and then really prodigious students, postdocs and collaborators. Working with them has been a joy.
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about 2 months ago
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about 2 months ago
Excited to share our new preprint on BioRxiv! A collaborative effort spanning many years and several labs to uncover what the germline chromosomes of Paramecium really look like. π
www.biorxiv.org/content/10.1...
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The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of Helitrons
Background. Paramecia belong to the ciliate phylum of unicellular eukaryotes characterized by nuclear dimorphism. A diploid germline micronucleus (MIC) transmits genetic information across sexual gene...
https://www.biorxiv.org/content/10.1101/2025.11.06.686955v1.article-info
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Interesting stuff on the most common
#virus
of
#Drosophila
!
academic.oup.com/ve/advance-a...
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https://academic.oup.com/ve/advance-article/doi/10.1093/ve/veaf089/8314014
about 2 months ago
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Tanja Stadler
2 months ago
Open position at the Swiss Institute of Bioinformatics: We are looking for a Director of the Center of Pathogen Bioinformatics
apply.refline.ch/499599/0346/...
I am in the Center's steering board together with fantastic colleagues (Emma Hodcroft
@firefoxx66.bsky.social
, Richard Neher
@neher.io
, and
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Director, Center for Pathogen Bioinformatics
The Centre for Pathogen Bioinformatics (CPB) is a unit of SIB which offers expertise and services in pathogen bioinformatics, computational molecular epidemiology and related multi-site project manage...
https://apply.refline.ch/499599/0346/pub/2/index.html
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Armando Rosario-LebrΓ³n
about 2 months ago
Join me in Edinburgh on the 22nd of November for the
@royentsoc.bsky.social
Outreach, Culture & Education SIG meeting at the National Museum of Scotland! If you missed the abstract deadline, you can still submit a poster until 10 Nov. π§ͺ
#bugsky
#entomology
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POPGROUP59
about 2 months ago
Hi Folks ! Just a few more days to register for the POPGROUP meeting (deadline = this Monday 10/11/2025). Join us in the beautiful city of
#Lille
just across the Channel for three exciting days of science and more !
www.hautsdefrancetourism.com/destinations...
-->
populationgeneticsgroup.org.uk
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Out now! From Jarrod Hadfield and Manas Geeta Arun: How to estimate the additive genetic variance for relative fitness from changes in allele frequency:
academic.oup.com/genetics/adv...
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Estimating the additive genetic variance for relative fitness from changes in allele frequency
Abstract. The rate of adaptation is equal to the additive genetic variance for relative fitness (VA) in the population. Estimating VA typically involves ob
https://academic.oup.com/genetics/advance-article/doi/10.1093/genetics/iyaf232/8305445
2 months ago
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Wikimedia Foundation
2 months ago
Transparency makes
@wikipedia.org
one of the most trusted sources of information on the internet. From History tabs tracking every edit to Talk pages revealing editorsβ discussions, Wikipedia runs on consensus decision-making that is visible to everyone. Learn more β‘οΈ
medium.com/freely-shari...
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Ben Longdon
2 months ago
Work with myself + β team
@xavh.bsky.social
&
@darrenobbard.bsky.social
on the 'Ecological and Evolutionary determinants of the bacterial microbiomes of UK moths'. Please get in touch if you are a Chinese student who likes host-pathogen interactions and would like to live in beautiful Cornwall.
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Luca Soldini
2 months ago
(1/9) Join us in Bern, Switzerland (8β11 Feb 2026) for our EMBO Workshop on Molecular Mechanisms of Selfish Elements and Strategies! Organized with Tanja Schwander, Laura Ross (
@laurarossevo.bsky.social
) and Axel Imhof.
meetings.embo.org/event/26-sel...
#EMBOselfishElements
#EMBOevents
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Molecular mechanisms of selfish elements and strategies
Certain genes, chromosomes, organelles, or entire sets of chromosomes can bias their transmission to the next generation, propagating themselves at the expense of the rest of the genome. Referred to β¦
https://meetings.embo.org/event/26-selfish-elements
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Bohdan &%@#ing Pavuk
about 1 year ago
if you see this post, your actions are: - if you have a spare buck, give it to Wikipedia, then repost this - if you don't have a spare buck, just repost your action is mandatory for the world's best source of information to survive
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Yuval Simons
2 months ago
Why do complex traits differ in their genetic architecture? In our new PLOS Biology paper, we will try to convince you that two simple scaling laws drive differences in the number, effect sizes and frequencies of causal variants affecting complex traits. Thread:
journals.plos.org/plosbiology/...
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Simple scaling laws control the genetic architectures of human complex traits
Genome-wide association studies have revealed that the genetic architectures of complex traits vary widely. This study shows that differences in architectures of highly polygenic traits arise mainly f...
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003402
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Transposable elements drive much of naturally occurring genetic lethality in Drosophila melanogaster
Recessive lethal mutations are widespread across studied species, with estimates suggesting that each individual carries at least one. Numerous lethal alleles persist in wild populations at higher fre...
https://www.biorxiv.org/content/10.1101/2025.10.16.682755v1
2 months ago
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DrosEU
3 months ago
We are in Bluesky and we are happy to share our two last consortium publications: the DrosEU expanded DEST dataset and a Continent-wide study of phenotypic differentiation among European
#Drosophila
melanogaster populations (1/7)
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Keith Matthews
3 months ago
We have a 3+ year post doc available in our lab to study trypanosome transmission and virulence. Combined wet lab and bioinformatics expertise preferred. Please apply via the HR link (
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
). Find out more about us in the link below.
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The Matthews Lab | Biology
The Matthews Lab
https://biology.ed.ac.uk/the-matthews-lab
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PLOS Biology
3 months ago
Fungal
#GenomeSize
variation is largely driven by TEs & lineage-specific genome defenses.
@tbadet.bsky.social
&
@danielcroll.bsky.social
show that presence/absence of RIP mutation systems influences
#genome
architecture, identifying a likely novel defense mechanism
@plosbiology.org
π§ͺ
plos.io/4hcC5tx
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Ben Hopkins
3 months ago
The Hopkins Lab (hopkins-lab.com) at the University of Florida is looking to recruit a postdoc to work on the genetics of organ function and evolution across Drosophila and beyond. Please visit
tinyurl.com/vcsjpmzz
or email me for more info. And please RT or send to anyone who might be interested!
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Just past 20K IDs on
#iNaturalist
!
3 months ago
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UCU Edinburgh
3 months ago
@edinburgh-uni.bsky.social
we're wondering if UoE management are proud to be the top of the 'slash jobs' league table?
www.timeshighereducation.com/news/cuts-eq...
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Cuts equivalent to 15,000 jobs planned at UK universities β UCU
Proposed job losses almost triple since March as unions prepare to vote on nationwide industrial action
https://www.timeshighereducation.com/news/cuts-equivalent-15000-jobs-planned-uk-universities-ucu
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James Briscoe
3 months ago
Very sad news, John Gurdon has died. A developmental biologist's developmental biologist, Nobel prize winner His work is the foundation of much of today's dev & stem cell bio. An inspiration to many, including me. Always asking questions & wanting the answers
www.magd.cam.ac.uk/news/profess...
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Professor Sir John Gurdon FRS (1933-2025) | Magdalene College
Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.
https://www.magd.cam.ac.uk/news/professor-sir-john-gurdon-frs-1933-2025
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Ben Longdon
3 months ago
Research assistant + postdoc position on a NERC funded project working w
@darrenobbard.bsky.social
and collaborating with
@savebutterflies.bsky.social
on the ecological and evolutionary drivers of the virome of UK moths
@uniexecec.bsky.social
. Descriptions below and links here
benlongdon.com/join/
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xkcd.com/3056/
(seen via
@annikabarber.bsky.social
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RNA
https://xkcd.com/3056/
3 months ago
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Katharine Khamhaengwong
3 months ago
i'm participating in an inaturalist project where anyone in europe can get their specimens dna tested for free, would be cool to have some more participants in some of the countries w/o little orange square on them (download the app! take photos of mushrooms!)
www.inaturalist.org/projects/myc...
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Mia Levine
3 months ago
Check out this new Levine-Lampson collaboration, led by the talented Hyuk-Joon Jeon. We explored the consequences of inheriting long telomeres from dad and short telomeres from mom. Or the reciprocal. Turns out, parent-of-origin matters (in mice, at least).
authors.elsevier.com/c/1loW-3QW8S...
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https://authors.elsevier.com/c/1loW-3QW8SA47k
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Great story! (Although I think that this is a TE, not an endogenous retrovirus)
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3 months ago
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POPGROUP59
3 months ago
Exciting news! The next
#PopGroup
meeting will take place in Lille π, France, 7β9 January 2026 β just 1 hour by train from London, Brussels, and Paris. This year, PopGroup will also host ALPHY, the annual meeting of Evolutionary Genomics. More info:
populationgeneticsgroup.org.uk
See you there !
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Population Genetics group 59
https://populationgeneticsgroup.org.uk/
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Ben Longdon
3 months ago
2 job adverts on a NERC project w myself +
@darrenobbard.bsky.social
on βWhat determines the virome: ecology and the environment, evolution, or species history?β early 2026 in
@uniexecec.bsky.social
- Postdoc:
jobs.exeter.ac.uk/hrpr_webrecr...
- RA:
jobs.exeter.ac.uk/hrpr_webrecr...
Pls share!
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