@smishra677.bsky.social
📤 11
📥 14
📝 0
reposted by
Matthew Hahn
22 days ago
New paper led by
@yadirapga.bsky.social
! Opossums have babies at 6-months of age, but are still highly male-biased in their mutations
academic.oup.com/genetics/adv...
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Low mutation rate but high male-bias in the germline of a short-lived opossum
Abstract. Age and sex have been found to be important determinants of the mutation rate per generation in mammals, but the mechanisms underlying these fact
https://academic.oup.com/genetics/advance-article-abstract/doi/10.1093/genetics/iyaf177/8244971
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31
18
reposted by
Genetics Society of America
2 months ago
In
#GENETICS
,
@3rdreviewer.bsky.social
and
@smishra677.bsky.social
show it is possible to estimate recombination solely using the allele frequency spectrum and provide a genealogical interpretation of the results, showing how
#MachineLearning
can provide insights into biology.
buff.ly/emixz9W
0
25
7
reposted by
Matthew Hahn
4 months ago
Our paper (w/
@smishra677.bsky.social
) is now out in Genetics!
academic.oup.com/genetics/adv...
add a skeleton here at some point
0
61
17
reposted by
Matthew Hahn
8 months ago
New paper with Sarthak Mishra! Maybe it will bring you some joy given all this (waves arms around). "Estimating recombination using only the allele frequency spectrum" 1/2
www.biorxiv.org/content/10.1...
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Estimating recombination using only the allele frequency spectrum
Standard methods for estimating the population recombination parameter, rho, are dependent on sampling individual genotypes and calculating various types of disequilibria. However, recent machine lear...
https://www.biorxiv.org/content/10.1101/2025.02.01.635998v1
3
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