Yadira Peña-García
@yadirapga.bsky.social
📤 167
📥 475
📝 0
PhD candidate at IU
reposted by
Yadira Peña-García
Matthew Hahn
about 2 months ago
Have you ever wondered: just how strong *is* the evidence for Muller's ratchet on mtDNA? Well, wonder no more! (Project led by Yu Mo, with
@smishra677.bsky.social
and
@yadirapga.bsky.social
) "No molecular evidence for Muller's ratchet in mitochondrial genomes"
www.biorxiv.org/content/10.6...
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No molecular evidence for Muller's ratchet in mitochondrial genomes
Muller's ratchet predicts that non-recombining genomes can accumulate deleterious mutations, though molecular evidence for it is rare. Previous studies have tried to detect ratchet-like behavior in mi...
https://www.biorxiv.org/content/10.64898/2025.12.16.694700v1
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reposted by
Yadira Peña-García
Matthew Hahn
5 months ago
New paper led by
@yadirapga.bsky.social
! Opossums have babies at 6-months of age, but are still highly male-biased in their mutations
academic.oup.com/genetics/adv...
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Low mutation rate but high male-bias in the germline of a short-lived opossum
Abstract. Age and sex have been found to be important determinants of the mutation rate per generation in mammals, but the mechanisms underlying these fact
https://academic.oup.com/genetics/advance-article-abstract/doi/10.1093/genetics/iyaf177/8244971
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reposted by
Yadira Peña-García
Matthew Hahn
about 1 year ago
New paper led by
@glom.bsky.social
! "Unprecedented female female bias in the aye-aye, a highly unusual lemur from Madagascar" 1/
journals.plos.org/plosbiology/...
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23
reposted by
Yadira Peña-García
Matthew Hahn
about 1 year ago
New paper led by
@yadirapga.bsky.social
! Even though opossums have kids at 0.5 years, they still have typical male-biased mutation (though not quite as high as humans). "Low mutation rate but high male-bias in the germline of a short-lived opossum"
www.biorxiv.org/content/10.1...
loading . . .
Low mutation rate but high male-bias in the germline of a short-lived opossum
Age and sex have been found to be important determinants of the mutation rate per generation in mammals, but the mechanisms underlying these factors are still unclear. One approach to distinguishing b...
https://www.biorxiv.org/content/10.1101/2024.12.05.627076v1
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