Alejandro Burga
@arburga.bsky.social
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A.d.i.d.a.s. All day I dream about science. Group Leader at IMBA. Genomics & evolution. Peruano.
reposted by
Alejandro Burga
Mia Levine
8 days ago
How to keep in step when your (protein) partner speeds up… Here we investigated the adaptive remodeling of a protein-protein interaction surface essential for telomere protection. Congrats to whole team!
www.science.org/doi/10.1126/...
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Rapid compensatory evolution within a multiprotein complex preserves telomere integrity
Intragenomic conflict with selfish genetic elements spurs adaptive changes in subunits of essential multiprotein complexes. Whether and how these adaptive changes disrupt interactions within such comp...
https://www.science.org/doi/10.1126/science.adv0657
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Alejandro Burga
Ă–sterreichische Akademie der Wissenschaften
5 days ago
Last call! 📢 Don’t miss Brenda Schulman at the upcoming Hans Tuppy Lecture tommorrow, sharing fresh insights into the dynamic regulation of the ubiquitin–proteasome system!
@univie.ac.at
@mpibiochem.bsky.social
www.oeaw.ac.at/detail/veran...
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Visualisierung von Ubiquitin-vermittelter Regulation
Eine enorm vielseitige Möglichkeit Proteine und Membranfunktionen zu regulieren, basiert auf der Vermittlung des kleinen Proteins Ubiquitin. Die Biochemikerin Brenda Schulman stellt die Zusammenhänge ...
https://www.oeaw.ac.at/detail/veranstaltung/visualisierung-von-der-ubiquitin-vermittelter-regulation
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Alejandro Burga
Jonathan Pettitt
8 days ago
C. elegans researchers were early adopters of open science: "The development of common resources and the belief that research findings and mutant strains should be freely shared has propelled worm research to the forefront"
www.pnas.org/doi/10.1073/...
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From nematode to Nobel: How community-shared resources fueled the rise of Caenorhabditis elegans as a research organism | PNAS
Experimental organisms such as the nematode Caenorhabditis elegans are fundamental to biological discovery. The success of C. elegans research has ...
https://www.pnas.org/doi/10.1073/pnas.2522808122
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reposted by
Alejandro Burga
Carlos Ribeiro
10 days ago
Thrilled to share our new paper! With
@tomtom-auer.bsky.social
team, we asked how
#evolution
reshapes what animals
#eat
to match their ecological niches. Using pan-neuronal Ca2+ imaging, we show that the changes are in how the brain processes
#taste
. Link
@nature.com
:
www.nature.com/articles/s41...
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Evolution of taste processing shifts dietary preference - Nature
Calcium imaging of taste neurons and the ventral brain provides insight into evolutionary divergence of food choice in Drosophila species, supporting a role of sensorimotor processing in addition to p...
https://www.nature.com/articles/s41586-025-09766-6
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reposted by
Alejandro Burga
Polina Tikanova
11 days ago
Happy to share that my PhD project is finally published!🪱✨ Selfish genes are found across the tree of life. They can disrupt inheritance patterns and at the same time act as units for molecular innovation. Here we tried to answer one big question: how do selfish genes emerge in the first place?
add a skeleton here at some point
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Alejandro Burga
Vienna BioCenter Scientific Training
12 days ago
The
Vienna BioCenter
Summer School 2026 call is now open for talented undergrads, it's a great opportunity for students who are interested in graduate study in the life sciences. Georg Busslinger from
CeMM
is recruiting! Please share
https://training.vbc.ac.at/summer-school/
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Alejandro Burga
Institute of Molecular Biotechnology
12 days ago
🚨 New paper alert! Scientists in the Burga lab show for the first time how toxin-antidote elements—selfish genetic elements that perpetuate by poisoning those embryos that don’t inherit them—evolved from normal cellular proteins. More:
https://imba.science/3M3fRyq
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🪱 Selfish genes are everywhere and drive some of biology’s biggest innovations (CRISPR, antibody recombination, epigenetics). Yet almost no one asks the obvious question: how does a selfish gene begin? Our new manuscript uncovers how selfishness can emerge directly from the host genome.
12 days ago
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