make sure to check out this great meeting 👇

Check out this beautiful paper by @richardcsilva.bsky.social et al., out now in @natcomms.nature.com. Great new DSB sensors to track DNA break formation and repair in real-time www.nature.com/articles/s41...

Registration is open!🧬 Join us at Egmond aan Zee (April 19–24, 2026) for the next DNA Repair Meeting. We have an amazing line-up of speakers. 📅 Deadline for early registration: Jan 10, 2026 🔗 dnarepairmeeting-egmond2026.com

Thrilled to share that the final piece of my PhD work is now on bioRxiv! biorxiv.org/content/10.1... With support from @nvidia and the @NSF, we used AlphaFold to screen 1.6M+ protein pairs, revealing thousands of potential novel PPIs. All data can be viewed at predictomes.org/hp

We are excited to welcome Evi Soutoglou and @rubenvanboxtel.bsky.social as our guest speakers at the upcoming GIIN webinar on Tuesday, November 4th at 5 PM Rome / 11 AM NYC. Join us on zoom: uniroma1.zoom.us/j/95149984403 Register here to become part of our community: docs.google.com/forms/d/e/1F...

We have an open position for a PhD student to join our team. If you have an interest in cancer biology, genome maintenance, or both, please apply! Details can be found in the link below. With @marcelvanvugt.bsky.social. werkenbijumcg.nl/-/vacatures/...

The Genome Integrity Webinar Series continues on Tuesday, May 6th at 5PM (Rome) / 11AM (New York) with an exciting discussion on DNA damage response and repair @kajastelab.bsky.social Join via Zoom: uniroma1.zoom.us/j/95149984403

Very exciting work by the Tijsterman lab www.biorxiv.org/content/10.1...

A must for all DNA repair aficionados! Egmond DNA Repair Meeting → April 19–24, 2026 🇳🇱 ✔️ Confirmed top speakers ✔️ Ample opportunities for talks & posters Don’t miss it: dnarepairmeeting-egmond2026.com

@puckknipscheer.bsky.social, @luijsterburglab.bsky.social, @marcelvanvugt.bsky.social, @sylvie-noordermeer.bsky.social, @titiasixma.bsky.social, @marcelvanvugt.bsky.social, @marteijnlab.bsky.social

Extremely happy to share that my main PhD project about CIP2A-TOPBP1 and the SMX complex is now available online as pre-print. Huge thanks to all co-authors but especially @marcelvanvugt.bsky.social for giving me the opportunity to work on this exciting project! www.biorxiv.org/content/10.1...

REV7 functions with REV3 as a checkpoint protein delaying mitotic entry until DNA replication is completed

1/Out today in @naturecomms.bsky.social, “A CPC-shelterin-BTR axis regulates mitotic telomere deprotection”. Here we identify the mechanism that unwinds telomere-loops (t-loops) during mitotic arrest to activate the DNA damage response and signal mitotic stress. www.nature.com/articles/s41....

Happy to post a new study on BioRxiv, where we show Integrated Stress Response activation as an off-target effect of multiple clinically evaluated WEE1 inhibitors. Team effort with the lab of Dan Durocher @durocher1.bsky.social and many others. www.biorxiv.org/content/10.1...

We show transcriptomic buffering of tumour suppressor loss via syn. lethal genes is not anecdotal but a cancer hallmark. Buffering also seen in BRCAness, predicts penetrant syn leth effects and outcome. @icr.ac.uk @cancerresearchuk.org @breastcancernow.bsky.social www.nature.com/articles/s41...

SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026.   Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute). www.embl.org/about/info/c...

Nice resource! #AlphaFold #PPI #ProteinInteractions Predictomes, a classifier-curated database of AlphaFold-modeled protein-protein interactions: Molecular Cell www.cell.com/molecular-ce...

*Tenured full Professorship in Genetics and Molecular Cell Biology* at the University Of Cologne, Germany It's an opportunity to rebuild the place that used to be home to luminaries including Benno Müller-Hill, Max Delbruck, Campos-Ortega, Diethard Tautz Maria Leptin, Thomas Langer

Beautiful work by the Lemmens lab! www.biorxiv.org/content/10.1...

exciting work: RNA-mediated tethering of DNA during mitosis www.biorxiv.org/content/10.1...

🚨𝐌𝐚𝐣𝐨𝐫 𝐉𝐨𝐛 𝐀𝐥𝐞𝐫𝐭!🚨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring 𝟔 𝐏𝐡𝐃&𝐩𝐨𝐬𝐭𝐝𝐨𝐜𝐬 to join the new Center for Epigenetic Cell Memory (EpiC) in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!

Dear all, Postdoc positions are available to work on (1) the role of DNA strand break repair proteins during DNA replication and (2) the molecular/structural biology of XRCC1 protein complexes, as part of our work on genetic diseases & cancer. Contact me if interested: [email protected]

Excited to present Social DNAing tomorrow. I’ll talk about our work led by @szmyd-radoslaw.bsky.social in collaboration with @radoncdocgee.bsky.social. 12 pm Eastern USA Thanks Shan Zha for the invite. www.cancer.columbia.edu/research/pro...

🌟Check out new online content: study from Daniel Dauch's lab: doi.org/10.1038/s430...

Today @naturesmb.bsky.social 🥳, we report that the activation of NF-κB after DNA damage can occur through two distinct mechanisms. While ATM triggers NF-κB activation after DSBs, we found that IRAK1 specifically induces NF-κB in response to DNA damage causing transcriptional stress.

Mark your calendar: the next Egmond DNA repair meeting will take place in 2026 from April 19 - 24! You can pre-register to receive announcement here: forms.lumc.nl/lumc2/Egmond Registration will open by June 2025/

NEW in @science.org, so happy to contribute to our understanding of the molecular machine, Fidgetin-like 1 (FIGNL1), and elucidating the mechanism of why cells cannot survive when it is lost! #ScienceResearch science.org/doi/10.1126/... (1/7)

Announcing the NAR Cancer virtual 5th anniversary symposium: "Manipulating DNA repair and the DNA damage response to improve cancer therapy." First webinar Jan 9. In cooperation with Social DNAing at Columbia University. Read the program and register for free! academic.oup.com/narcancer/pa...

What are your plans for October 2025? It would be a fantastic time to visit Norway for the Endogenous DNA Damage and Repair conference with a stellar set of speaker covering a wide range of topics. www.endodnadamage.com

New at NAR Cancer: Ex vivo functional test for HR proficiency applied to a cohort of ovarian cancer PDX models: a way to identify PARPi-sensitive tumors lacking BRCA1/2 alterations. From Francien Talens et al., Univ of Groningen. academic.oup.com/narcancer/ar...

Happy to share our study by Francien Talens and many colleagues on RAD51 foci formation as a functional marker for PARPi sensitivity in ovarian cancer PDX models. academic.oup.com/narcancer/ar...

Two fully funded PhD opportunities in our lab. Interdisciplinary, DNA replication, cancer research, structural biology… deadlines in early Jan. Open to international students. t.co/WEJJIU4zU4 www.findaphd.com/phds/project...

#Chromothripsis leads to the acquisition of multiple genomic aberrations. Now out in Nat Rev Cancer: 1) A #Review from Simovic-Lorenz & Aurelie Ernst, @dkfz.bsky.social, covering mechanistic models of chromothripsis & its role in cancer and progression. 👉 bit.ly/4fy8pFo

Hi BlueSky! It's great to be here. Here's a handy Starter Pack of DNA repair & genome stability groups that I found so far go.bsky.app/NvFWKvL

ok, Genome Stability people. Here are our two starter packs - since I can't pin them both independently to my profile, have to make a new post. Still adding new people to the second pack. As usual, please reach out if you would like to be added! bsky.app/starter-pack... bsky.app/starter-pack...

Today, the 12th annual PhD day for oncological research at the UMCG/University of Groningen is organized. Looking forward to great talks by PhD students and keynote speaker prof. Carla van Herpen!

Very happy to see it out in the open! Congrats @fmattiroli.bsky.social 🎉

Announcing the next EMBO Chromosome Segregation and Aneuploidy Meeting! Italy 2025. Please register and join us for another exciting and friendly meeting in a beautiful location meetings.embo.org/event/25-ane...

Leonid Mirny and I wrote this for all interested in chromosomes: "The chromosome folding problem and how cells solve it" www.cell.com/action/showP...