Milo B. Fasken, Ph.D. (@milofasken.bsky.social)

Nuclear exosome targeting complex safeguards hematopoietic stem cell self-renewal and genomic integrity through resolving R loops R loops form during transcription, threatening the genomic stability of hematopoietic stem cells (HSCs) and lymphoma cells. Pan et al. report that ZCCHC8 safeguards the genome integrity and self-renew... https://www.cell.com/cell-reports/fulltext/S2211-1247(25)01422-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124725014226%3Fshowall%3Dtrue