Colliding ribosomes are potent signals of cellular stress. But do cells use ‘programmed’ ribosome collisions to regulate gene expression? I’m excited to present a new story from my lab led by Frederick Rehfeld(@fred-rehfeld.bsky.social) which revealed that the answer is YES! Read on to find out how👇

Congratulations @kateodonnell-lab.bsky.social and Shayna!

#Worm25 Congratulations to Jacob (Ortega) for the Sydney Brenner thesis award!!! Truly a spectacular young scientist! Keep an eye out for him!! Jacob is a postdoc in Josh Mendell’s lab at UTSW right now.

I am pleased to present our latest pre-print describing our identification of the long-sought triggers for target-directed microRNA degradation (TDMD) of miR-322 and miR-503, work led by Collette LaVigne and Jaeil Han. For more info, read on! 👇 www.biorxiv.org/content/10.1...

It's difficult to focus on science with everything going on, but I still enjoy hearing about other people's work here, so I want to continue sharing ours. Congrats to postdoc Jong-Sun Lee for his outstanding work published in @cp-molcell.bsky.social! Details in thread👇 www.cell.com/molecular-ce...

A nice journal club intro by Amy McDermott at PNAS to the excellent paper from @mendell-lab.bsky.social and colleagues #RNAsky #RNAbiology www.pnas.org/post/journal...

Great thread on our paper from Jan👇

I’m thrilled to share a collaborative story from @Mendell_lab and Jan Erzberger labs, led by postdoc extraordinaire Xiaoqiang Zhu. We showed that in addition to their canonical decoding function, tRNAs play a key role in regulating mRNA stability during translation! www.science.org/doi/10.1126/...

Happy to join you all over here at this better place! I'm excited to share a new paper with this community! 👇