Matthias Krause
@matthias-krause.bsky.social
📤 302
📥 374
📝 30
Cell migration and endocytosis research lab
https://cytoskeleton.wixsite.com/krauselab
pinned post!
Exciting new findings: Wnt-receptor endocytosis is required for canonical Wnt activation, yet uptake mechanisms has been controversial. We resolve this by showing that Wnt3a triggers rapid Clathrin- and Fast Endophilin-Mediated LRP6 endocytosis at low concentrations sufficient for Wnt activation.
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The Actin regulator Mena promotes Wnt signalosome endocytosis and Wnt signalling
Wnt signaling controls embryonic development and tissue maintenance. Endocytosis of Wnt-receptors is required for signalling, yet uptake mechanisms remain poorly understood. Here, we identify the acti...
https://www.biorxiv.org/content/10.1101/2025.11.24.690281v1
6 months ago
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Matthias Krause
Pablo J. Sáez
5 days ago
1 week to start🔥 New
@focalplane.bsky.social
webinar series focused on
#CellMigration
, register & join us▶️, it will be fun! pls spread the word, in the next one, ECRs could apply to show their work ;) ▶️ to register:
focalplane.biologists.com/2026/05/29/n...
@dgz.bsky.social
@the-node.bsky.social
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Matthias Krause
Bryjalab
26 days ago
Thrilled to see our study out in Science Advances 🔥
www.science.org/doi/10.1126/...
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Matthias Krause
Amy Beedle
about 1 month ago
My postdoc work with
@pcusachs.bsky.social
is finally out! We find that fibrillar adhesions play an important role regulating the timescales of nuclear mechanotransduction. You can read all about it here :
www.nature.com/articles/s41563-026-02590-x
Huge thanks to everyone involved!!
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Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton - Nature Materials
Nuclear deformation and mechano-signalling are regulated by the coupling of vimentin cytoskeleton to the extracellular matrix through fibrillar adhesions, modulating the timescale of mechanotransducti...
https://www.nature.com/articles/s41563-026-02590-x
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Matthias Krause
British Society for Cell Biology
about 2 months ago
That's a wrap for
#DynamicCellVI
Thank you to all presenters for sharing their amazing science. The quality of ECR talks and posters has been outstanding. Thanks to
@viji-draviam.bsky.social
@matthias-krause.bsky.social
&
@biochemsoc.bsky.social
for organising
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Matthias Krause
3 months ago
Actin-membrane interface stress regulates Arp2/3-branched actin density during lamellipodial protrusion
www.biorxiv.org/content/10.6...
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https://www.biorxiv.org/content/10.64898/2026.03.06.710140v1
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Leone Rossetti
3 months ago
Interested in a PhD in collective cell migration & mechanobiology? I'm looking to support a candidate applying for a fully funded UK/Home PhD. The project studies the biophysics of migrating cells, using force measurements & optogenetics, with collaborators in Japan.
#mechanobiology
#PhD
eb4bm.org
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Home - Engineering Biology For Biomedicine
Engineering Biology for Biomedicine A UKRI:BBSRC Centre for doctoral training Why EB4BM “ Our graduates bridge fundamental biological design principles with biomedical bottlenecks, delivering engineer...
https://eb4bm.org/
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Matthias Krause
Karen J Liu
3 months ago
Fully funded PhD post, UK/Home student, starting 01/06/26. Interested in working at the interface of dev bio, biophysics and cell biology? Great collaboration with Amy Beedle and
@leonerossetti.bsky.social
Informal enquiries welcome. Deadline 15/03
#neuralcrest
www.kcl.ac.uk/study-legacy...
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Multiscale Models for Life (MM4L) Centre for Doctoral Training Funded Studentship: How ECM changes shape cellular decision making
Embryo, neural crest, developmental biology, cell biology, cell migration, biophysics, mechanobiology, bioengineering.
https://www.kcl.ac.uk/study-legacy/funding/multiscale-models-for-life-mm4l-centre-for-doctoral-training-funded-studentship-how-ecm-changes-shape-cellular-decision-making
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Matthias Krause
David Drubin
3 months ago
Class-I myosin responds to changes in membrane tension during clathrin-mediated endocytosis in human induced pluripotent stem cells | PNAS
www.pnas.org/doi/10.1073/...
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Class-I myosin responds to changes in membrane tension during clathrin-mediated endocytosis in human induced pluripotent stem cells | PNAS
Clathrin-mediated endocytosis (CME) is an essential cellular process that needs to operate efficiently across a wide range of conditions. Internali...
https://www.pnas.org/doi/10.1073/pnas.2532817123
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Abstract deadline this Sat 21 Feb 2026! Don't miss the Dynamic Cell VI conference, Reading, UK, April 2026! Co-organised by
@bscb-official.bsky.social
and
@biochemsoc.bsky.social
with
@royalmicrosoc.bsky.social
and the Chinese Society for Cell Biology. Register now:
bit.ly/Dynamic-Cell-VI
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Dynamic Cell VI
https://bit.ly/Dynamic-Cell-VI
4 months ago
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Matthias Krause
Michael Way
4 months ago
Closing date is 19th Feb so why not go for it to enjoy the rain in London!
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Matthias Krause
Brett Collins
4 months ago
Looking forward to the 93rd UK Biochemical Society Harden Conference on “Endosomal-lysosomal network dysfunction in neurodegenerative disease” over the 1st to 4th of September 2026. Early bird deadline 1st June 2026.
www.eventsforce.net/biochemsoc/f...
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Matthias Krause
Loïc A. Royer 💻🔬🧪
4 months ago
1/ 🚀🧪🤖 Big update for
#Omega
— the LLM-powered autonomous agent for bioimage analysis in
@napari.org
! Custom LLM endpoints, layer actions, plugin extensibility, agentic widget maker, modernized UI, & 30+ fixes. Here's what's new in version *2026.2.8.2*:
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Michael Way
4 months ago
2nd postdoc job alert in the Crick Institute in London. Project will examine the role of motors & the cytoskeleton (actin, septins and microtubules) during vaccinia virus egress using biochemical, structural & cellular approaches + live cell imaging. spread the word.
crick.ac.uk/WayPostdoc20...
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Postdoctoral Fellow - Cellular signalling and cytoskeletal function lab
http://crick.ac.uk/WayPostdoc2026-2
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Matthias Krause
Biochemical Society
4 months ago
Do you know a exceptional PhD candidate whose very promising research career has been interrupted for non-academic reasons? Encourage them to apply for the Krebs Memorial Scholarship - now accepting applications for the 2026/27 academic year! Deadline 3 April
https://ow.ly/Pufm50Y7K5G
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Matthias Krause
4 months ago
Reconstructing Actin Dynamics of the Leading Edge from Observational Data
www.biorxiv.org/content/10.6...
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Early bird deadline: Save £100: This Wed 21 January 2026! Dynamic Cell VI conference, Reading, UK, April 2026! Co-organised by
@bscb-official.bsky.social
and
@biochemsoc.bsky.social
with
@royalmicrosoc.bsky.social
and the Chinese Society for Cell Biology. Register now:
bit.ly/Dynamic-Cell-VI
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Dynamic Cell VI
https://bit.ly/Dynamic-Cell-VI
5 months ago
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Matthias Krause
Jennifer Waters
5 months ago
PIs & Group Leaders, do your trainees need to learn light microscopy and image analysis? Send them to us! Financial aid is available! Applications due Friday 1/30.
meetings.cshl.edu/courses.aspx...
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Quantitative Imaging: From Acquisition to Analysis
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
https://meetings.cshl.edu/courses.aspx?course=C-QICM&year=26
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Matthias Krause
Pablo J. Sáez
5 months ago
#FluorescenceFriday
Proud of our the last paper
@cellcommlab.bsky.social
& 1st one of
@jboixcampos.bsky.social
We continue to study
#CellMigration
& how cells decide where to go: ↖️↗️⬇️? (movie of the actin
#cytoskeleton
) Full
www.science.org/doi/10.1126/...
@focalplane.bsky.social
@science.org
🧪🔬
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Matthias Krause
British Society for Cell Biology
6 months ago
Don't forget to register for our Spring Meeting: Dynamic Cell VI A joint meeting with the
@biochemsoc.bsky.social
Super early bird registration ends 21st Jan
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Matthias Krause
Helen Matthews
6 months ago
Excited to be a speaker at Dynamic Cell VI. Always a great meeting
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Matthias Krause
Lucien Hinderling
11 months ago
PAPER OUT ✨ What if you could use your microscope as a 3D printer? Prototype microfluidics in-house, <5$ in material costs per chip. From idea to experiment within a day. Now published in Lab-on-a-Chip (open-access):
doi.org/10.1039/D5LC...
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reposted by
Matthias Krause
epithelial mechanics fan club
6 months ago
Want even smaller features? We recently published a method to convert your microscope into a microfabrication station, printing features from μm to cm scale for less than $5 in materials per design. Thread:
bsky.app/profile/lhin...
Paper:
bsky.app/profile/epim...
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reposted by
Matthias Krause
Romet/Jegou lab
6 months ago
📢 Deadline approaching fast 📢 to submit an abstract for the great cytoskeleton extravaganza!
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Matthias Krause
Michael Way
6 months ago
Are you interested in cytoskeleton and looking for a postdoc position? I will be advertising positions in the new year but happy to chat in person if you are attending ASCB
@ascbiology.bsky.social
in Philadelphia. Just drop me a line.
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Guillaume Jacquemet
6 months ago
Your periodic reminder that science is not done by a few selected "stars scientists". Science is done by hundred of thousands. Siloed money mean a few flashy discoveries and a lot of waste. Want to change things? Make funding accessible and stop funding calls with less than 2% success rate.
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Early bird registration: Save £100 - 21 January 2026! Dynamic Cell VI conference, Reading, UK, April 2026! Co-organised by
@bscb-official.bsky.social
and
@biochemsoc.bsky.social
with
@royalmicrosoc.bsky.social
and the Chinese Society for Cell Biology. Register now:
bit.ly/Dynamic-Cell-VI
6 months ago
0
3
3
Exciting new findings: Wnt-receptor endocytosis is required for canonical Wnt activation, yet uptake mechanisms has been controversial. We resolve this by showing that Wnt3a triggers rapid Clathrin- and Fast Endophilin-Mediated LRP6 endocytosis at low concentrations sufficient for Wnt activation.
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The Actin regulator Mena promotes Wnt signalosome endocytosis and Wnt signalling
Wnt signaling controls embryonic development and tissue maintenance. Endocytosis of Wnt-receptors is required for signalling, yet uptake mechanisms remain poorly understood. Here, we identify the acti...
https://www.biorxiv.org/content/10.1101/2025.11.24.690281v1
6 months ago
1
19
5
reposted by
Matthias Krause
Maik Bischoff
7 months ago
Super proud to be part of SFB1348 — and excited to share that I now officially have my own lab in Münster! 🎉🪰 We’ll study
#cellbio
&
#morphogenesis
, focusing on organ sculpting and
#chirality
in
#Drosophila
. I’ll soon hire my first
#PhD
student — feel free to reach out!
#juniorPI
#Science
#devbio
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Matthias Krause
Karen J Liu
7 months ago
Exciting new findings on mechanisms of Wnt signalosomes --from Sheng-yuan Wu's PhD project in
@matthias-krause.bsky.social
lab! Great collaborators, great story.
#xenopus
🐸
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Endocytosis of Wnt-receptors is required for signalling, yet uptake mechanisms remain poorly understood. We resolve a longstanding controversy by showing that Wnt3a triggers rapid Clathrin-Mediated and Fast Endophilin-Mediated LRP6 endocytosis at low concentrations sufficient for Wnt activation.
7 months ago
1
11
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reposted by
Matthias Krause
Grill Lab @ MPI-CBG
7 months ago
The Lab of Stephan Grill at MPI-CBG has finally made it to Bluesky and we also have a brand new homepage:
grill-lab.org
Check it out.
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Matthias Krause
Rainero lab
7 months ago
📣 Fully funded PhD position available in collaboration with
@jasonkinglab.bsky.social
in
@mcb-sheffield.bsky.social
BBSRC Yorkshire Bioscience DLA Programme: How do cells coordinate nutrient scavenging pathways? 📅 Deadline: 7th January 2026 More info 👇
www.findaphd.com/phds/project...
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BBSRC Yorkshire Bioscience DLA Programme: How do cells coordinate nutrient scavenging pathways? at University of Sheffield on FindAPhD.com
PhD Project - BBSRC Yorkshire Bioscience DLA Programme: How do cells coordinate nutrient scavenging pathways? at University of Sheffield, listed on FindAPhD.com
https://www.findaphd.com/phds/project/bbsrc-yorkshire-bioscience-dla-programme-how-do-cells-coordinate-nutrient-scavenging-pathways/?p189984
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Matthias Krause
Vicki Metzis
8 months ago
I am absolutely delighted to share the invited speakers for our upcoming
@bsdb.bsky.social
"Molecules to Morphogenesis" meeting! Registration and abstract submission is now open - join us!
bsdb.org/meetings/
March 23-26, 2026 - UK
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The cell dynamics conference in 2026 not to be missed: Dynamic Cell VI conference, Reading, UK, April 2026! Co-organised by
@bscb-official.bsky.social
and
@biochemsoc.bsky.social
with
@royalmicrosoc.bsky.social
and the Chinese Society for Cell Biology. Register now:
bit.ly/Dynamic-Cell-VI
8 months ago
0
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Matthias Krause
Krista Koeller
8 months ago
Dear funding agencies, I know we all want to discover the wonder drug that will cure the horrible diseases, but to do that, we need to invest in basic, unsexy, foundational research on how the systems work. Funding can’t all be drug development. Sincerely, Looking for basic research grants.
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Matthias Krause
British Society for Cell Biology
8 months ago
Registration is OPEN for our Spring Meeting: Dynamic Cell VI co-organised with
@biochemsoc.bsky.social
@royalmicrosoc.bsky.social
and the Chinese Society for Cell Biology
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Matthias Krause
bioRxiv Cell Biology
8 months ago
Optogenetic control of PLC-γ1 activity polarizes cell motility
https://www.biorxiv.org/content/10.1101/2025.10.09.681531v1
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In our revised NHSL1/2-FEME manuscript led by
@jonny-cope.bsky.social
we provide the additional functional insights that NHSL1 is not required for Dynamin recruitment but promotes carrier formation in Fast Endophilin Mediated Endocytosis (FEME) by increasing actin polymerisation at sites of FEME.
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Nance-Horan Syndrome-like 1 interacts with endophilin A2 and Ena/VASP proteins to promote fast endophilin-mediated endocytosis.
Endocytosis, crucial for various physiological processes, facilitates receptor and extracellular material uptake. Fast endophilin-mediated endocytosis (FEME), driven by endophilin A2 (EndoA2), enables...
https://www.biorxiv.org/content/10.1101/2024.10.23.619882v3
8 months ago
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Register for the Dynamic Cell VI conference, Reading, UK, April 2026! This conference focusses on all aspects of cell dynamics, co-organised by
@bscb-official.bsky.social
and
@biochemsoc.bsky.social
with
@royalmicrosoc.bsky.social
and the Chinese Society for Cell Biology.
bit.ly/Dynamic-Cell-VI
8 months ago
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Matthias Krause
Ankita Jha
8 months ago
If anyone ever wants to brush up on a lot of cell migration concepts don't forget we have several wonderful scientists who have given talks previously in cell migration seminars. I find it so comforting to go look at old videos, maybe someone else who will do as well!!
youtube.com/@cellmigrati...
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Cell Migration Seminars
Cell Migration Seminars every Tuesday at 16:00 BST.
https://youtube.com/@cellmigrationseminars4300?si=Ec_AanFyoUoqA0-4
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Matthias Krause
Siân Culley
8 months ago
BioImage analysis friends - King's are recruiting for a full-time, permanent facility position! Come and work with fun microscopes and fun people (and me!) - please share!
www.kcl.ac.uk/jobs/126345-...
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Bioimage Analysis Specialist | King's College London
https://www.kcl.ac.uk/jobs/126345-bioimage-analysis-specialist
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Matthias Krause
Migle Gabrielaite
9 months ago
Next, at
#EYSF2025
@reviewcommons.org
is presented by
@saramonaco-rc.bsky.social
. It’s journal-agnostic, concentrates on science only and can save time as the peer-reviewed preprints can easily be resubmitted. How great would it be if we could ditch publishing and switch to reviewed preprints?
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Matthias Krause
A/Prof Sam Stehbens PhD (She/Her)
8 months ago
I’m not sure as a community we **truely** acknowledged how powerful the
#CellMigrationSeminarSeries
series was at keeping us connected at such an uncertain time. Thank-you
@ankita13jha.bsky.social
@adamshellard.bsky.social
@drjenmitchell.bsky.social
&
@simplythebex.bsky.social
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Matthias Krause
Daniel J. Cohen (Princeton)
9 months ago
SCHEPHERD--the bioelectric cell herding platform built for YOU. Single cells, monolayers, organoids--this herds them all + new tricks. Plz try it-- we will *give* you parts! Teaser here of a steering a single cell. GS Yubin Lin's lifeblood with J. Yodh on piano; Celeste R. and Paul K. Thread 1/N
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Matthias Krause
Karen J Liu
10 months ago
Dev biologists! 3-yr postdoc position at King's, collaboration with Trizzino lab
@marcotrizzino.bsky.social
modelling CHD3 neural crest. We are looking for postdocs with mad embryology skills
@the-node.bsky.social
#developmental
@ccrb27.bsky.social
thenode.biologists.com/jobs/postdoc...
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Postdoctoral Research Associate: Modelling Neural Crest Anomalies (mouse/human) - the Node
The Liu lab is looking for a postdoc with a love of embryos and developmental biology! This post is part of an MRC-funded collaboration between Karen Liu’s lab at King’s College London and Marco Trizz...
https://thenode.biologists.com/jobs/postdoctoral-research-associate-modelling-neural-crest-anomalies-mouse-human/
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Matthias Krause
Christophe Le Clainche
10 months ago
🎓 My team is seeking a PhD student in Biochemistry & Cell Biology at I2BC, Paris-Saclay! 🔬 Study cytoskeletal signaling in collective cell migration 🌍 Fully funded, 3 yrs | 📍 Gif-sur-Yvette, France 🗓️ Apply by Aug 22 via the following link:
emploi.cnrs.fr/Offres/Docto...
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Matthias Krause
11 months ago
Drosophila as a model system to understand
#collagen
IV-related genetic disease. Learn how fly genetics and exploding brain tissue can inform on
#ECM
defects and pathological mechanisms. Team effort led by a very talented recent PhD graduate, Angus Nichols.
doi.org/10.1016/j.ma...
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Matthias Krause
Rockefeller University Press
11 months ago
In new
@jcb.org
study from Muziyue Wu et al.
@oweinerlab.bsky.social
, in vivo biochemistry sheds new light on how the WAVE complex templates the characteristic shape of lamellipodial protrusions.
rupress.org/jcb/article/...
#Cytoskeleton
#Actin
#Migration
#Motility
#Biophysics
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Matthias Krause
Juan Martin Serrano
11 months ago
I am so proud of
@jezcarlton.bsky.social
. What a magnificent inaugural lecture, many congratulations Professor Carlton!
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Matthias Krause
Anh Hoang Le, PhD 🏳️🌈
11 months ago
OMG, this is such a cool paper from Patrick Caswell's lab. They express Rab25-mCherry-GFP-nanobody in cells, microinject GFP-magnetic particles, then use a magnet to pull Rab25 to the plasma membrane to show that it can trigger actin protrusions! I want this system.
www.science.org/doi/10.1126/...
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Live-cell magnetic manipulation of recycling endosomes reveals their direct effect on actin protrusions to promote invasive migration
Repositioning of Rab25 vesicles containing formin and integrin cargos to the cell periphery promotes protrusion formation.
https://www.science.org/doi/10.1126/sciadv.adu6361
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