@henrydebelly.bsky.social @oweinerlab.bsky.social elegantly showed how migrating cells exhibit a long-range mutual activation and partitioning of GTPases at both the front and back of the cell, functioning as an integrated mechano-chemical system. He’s also recruiting for his new lab!🧑‍🔬#MBIMPG2025

WAVE complex forms linear arrays at negative membrane curvature to instruct #lamellipodia formation, say Muziyue Wu, Orion Weiner @oweinerlab.bsky.social and colleagues: rupress.org/jcb/article/... #Biophysics #Cytoskeleton #Migration #Motility #Actin

In new @jcb.org study from Muziyue Wu et al. @oweinerlab.bsky.social, in vivo biochemistry sheds new light on how the WAVE complex templates the characteristic shape of lamellipodial protrusions. rupress.org/jcb/article/... #Cytoskeleton #Actin #Migration #Motility #Biophysics