Join us in Sheffield! We are keen to support early career researchers in applying for independent research fellowships to join our friendly & collaborative environment, in areas related to gene expression, mechanistic cell biology & cancer biology. For more info 👇 sheffield.ac.uk/biosciences/...

Proud to have been awarded LEAF Silver (again) - with @helenkmatthews.bsky.social lab!! @mcb-sheffield.bsky.social

Amazing entries for our Christmas baking competition!!

📢 PhD opportunity: fully-funded BBSRC Yorkshire Bioscience project available @mcb-sheffield.bsky.social Interdisciplinary project on keratins in cell division combines cell biology, biophysics and in vivo Zebrafish imaging. 👇Apply by 7th Jan www.findaphd.com/phds/project...

📣 Paper alert: Ras signalling at the actin cortex: Coordinating local and global changes to cell morphology. @helenkmatthews.bsky.social pubmed.ncbi.nlm.nih.gov/41275567/

📢 Paper alert: Characterisation of cell-scale signalling by the core planar polarity pathway during Drosophila wing development. pubmed.ncbi.nlm.nih.gov/41347775/

Our external seminar speaker today will be Alexandra Davies, PhD from the University of Manchester "Location, location, location: subcellular spatial proteomics to map protein localisation in neurodegenerative diseases" 📍 Alfred Denny Conference Room 📅 3rd December - 1pm

We are delighted to host Juan Martin-Serrano today from @kingscollegelondon.bsky.social "Genome protection by the ESCRT machinery" 📍 Alfred Denny Conference Room 📅 19th November - 1pm

📣 Fully funded PhD position available in collaboration with @jasonkinglab.bsky.social in @mcb-sheffield.bsky.social BBSRC Yorkshire Bioscience DLA Programme: How do cells coordinate nutrient scavenging pathways? 📅 Deadline: 7th January 2026 More info 👇 www.findaphd.com/phds/project...

Our external seminar speaker today will be Peter Hill from @kingscollegelondon.bsky.social "How host-pathogen interactions can inform therapeutic strategies against relapsing invasive non-typhoidal Salmonella infections" 📍 Alfred Denny Conference Room 📅 5th November - 1pm

📢 Fully-funded 4-year MRC DiMeN PhD opportunity in our lab. 🔬 Exciting cancer cell biology collab with @maiblab.bsky.social & Liz Smythe @mcb-sheffield.bsky.social to use recombinant biosensors to image active KRAS in #pancreaticcancer 👇Apply by 4th Dec www.findaphd.com/phds/project...

We are delighted to host Prof Rob deBruin from @ucl.ac.uk today "Targeting Cell Cycle Control in Cancer" 📍 Alfred Denny Conference Room 📅 22nd October - 1pm

We are delighted to host Harsha Kantamneni today from the University of Bradford. "Endosomal Sorting Complex Required for Transport (ESCRT): Roles in receptor trafficking, signalling pathways, drug resistance and disease" 📍 Alfred Denny Conference Room 📅 18th October - 1pm

We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share. www.jobs.ac.uk/job/DOW912/s...

Congratulations to Shahd on passing her PhD viva!!!! Thanks to Christoph and Jason @jasonkinglab.bsky.social for examining

Amazing talk by Bella, from @helenkmatthews.bsky.social lab at #NECB2025

More fascinating talks this morning by our final year students Megan Poxon (@jasonkinglab.bsky.social & @helenkmatthews.bsky.social), Nada Alosaimi (C. Smythe lab), Zhe Bao (@erainerolab.bsky.social), @rlawson954.bsky.social @helenkmatthews.bsky.social) and Ashleigh Whelan (Wilson lab)

Great talks by our @mcb-sheffield.bsky.social speakers Grace Gilbert (@bose-lab.bsky.social & @tsakiridis.bsky.social), Francesca Brown (Humphreys lab) and Rob Hunton (@struttlab.bsky.social) at the 3rd year PGR symposium!! Back tomorrow morning - stay tuned!!

Here are our fantastic postdocs: Mona, Rachele & Eric @mcb-sheffield.bsky.social #NPAW2025 #PostdocAppreciationWeek

Well done to our PhD student @rlawson954.bsky.social 👏 on giving a talk on her data on keratins and mitotic mechanics at the MBI-MPG conference at @mbisg.bsky.social in Singapore! @mcb-sheffield.bsky.social

Are you a postdoc interested in the mechanisms of disease? Do you have a great record and an exciting vision? Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships. Deadline 30th September...pass it on! www.path.ox.ac.uk/work-with-us...

Interested in Pancreatic Cancer Research? We are gearing up to host our 7th Sheffield Pancreatic Cancer Research Network meeting! Check out the details at: sites.google.com/sheffield.ac... @mcb-sheffield.bsky.social @fohsheffield.bsky.social

Calling all meeting organizers… @biologists.bsky.social now have a calculator to estimate your event’s carbon footprint and to test various reduction scenarios. thenode.biologists.com/event-carbon...

🚨 JOB ALERT 🚨 We're hiring a Research Assistant – no PhD needed! Join us to explore the molecular mechanisms of receptor sorting in endosomes. Experience in protein expression/purification, cloning & cell culture desired 🧫🔬 Apply now 👉 www.nature.com/naturecareer... #STEMCareers #ResearchJobs

It was a pleasure to visit @sheffielduni.bsky.social last week presenting our work "Neutrophil metabolism faciliates metastasis by influencing immune & ECM landscapes" at @mcb-sheffield.bsky.social seminar series.Thanks @erainerolab.bsky.social for the invitation & all who made it a memorable visit

I am excited to share our new Sheffield Pancreatic Cancer Research Network website! Please check it out at... sites.google.com/sheffield.ac... @fohsheffield.bsky.social @mcb-sheffield.bsky.social

We are delighted to host @cassiejclarke.bsky.social today from the @cruk-si.bsky.social! "Neutrophil metabolism supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes" 📍 Alfred Denny Conference Room 📅 10th June - 1pm

📣 Postdoctoral position available!!! Are you interested in translating molecular cell biology into potential cancer therapy? This project will explore the role of EGFR trafficking in chemotherapy resistance in #breastcancer 🔬 Prof Liz Smythe lab 📅 Deadline: 3rd Jule 👇 www.jobs.ac.uk/job/DNJ622/r...

New addition to our lab's PhD Wall of Fame - Bian 🇸🇾 #WeAreInternational @mcb-sheffield.bsky.social @sheffielduni.bsky.social

Hot off the press for your Friday morning! 🔥 Our new (and highly revised!) preprint is out. It significantly expands on our previous work, unveiling exciting new data on how CBP's intrinsically disordered regions (IDRs) regulate genes. Link to preprint: tinyurl.com/5npjkyps #IDRs #condensates #CBP

Well done Bian!!

We are delighted to host @vickysanzmoreno.bsky.social today from the @icr.ac.uk! "Biomechanical hallmarks and vulnerabilities of metastatic cancer cells" 📍 Alfred Denny Conference Room 📅 4th June - 1pm @insigneoinstitute.bsky.social @sheffielduni.bsky.social @sheffielduni.bsky.social

Amazing talk by Ife at the @mcb-sheffield.bsky.social 2nd year PGR symposium

Bia doing a super job with her talk at the @mcb-sheffield.bsky.social 2nd year symposium!! 👏👏

Second year PGR symposium with @drn-sheffield.bsky.social! Exciting day full of science 🧬

📣 New paper alert! The El-khamisy lab uncovered how a key protein, NuMA, helps repair damaged DNA and protect important control regions of our genome, especially after oxidative stress. 🛡️ Protecting the genome = protecting health. www.cell.com/cell-reports...

Fantastic talk from @nicola-carruthers.bsky.social at today's @mcb-sheffield.bsky.social postdoc talk series! #CBP #RNAs #enhancers and everything in between- smashed it! 👏

📣 New paper alert!! From the Erdman lab in @cp-iscience.bsky.social "Mechanical control of the alternative splicing factor PTBP1 regulates extracellular matrix stiffness induced proliferation and cell spreading". pubmed.ncbi.nlm.nih.gov/40241749/

Liz Smythe is presenting her work at #TUOSCancerResearch away day

MCB external seminar today: Prof Deborah Tweedle @newcastleuni.bsky.social "Neuroblastoma:The ultimate chameleon of cancer genetics" 📍 Alfred Denny Conference Room 📅 4th April - 1pm

MCB external seminar today: Dr Peter Martin @icr.ac.uk "Mitotic Genome Stability:  The Key to Precision Cancer Therapy?" 📍 Alfred Denny Conference Room 📅 2nd April - 1pm

Excited to share that our latest paper is out today!!! 'The protease ADAMTS5 controls ovarian cancer cell invasion, downstream of Rab25' - great effort by Sherry and Rachele (1/6) @febsj.bsky.social @mcb-sheffield.bsky.social febs.onlinelibrary.wiley.com/doi/full/10....

@vichart33.bsky.social and Meg representing the lab at @bscb-official.bsky.social @biologists.bsky.social #biologists100 @mcb-sheffield.bsky.social

Fantastic talk from PhD student Zhe Bao from @erainerolab.bsky.social @mcb-sheffield.bsky.social in the Cell Growth & Proliferation session at #biologists100

Congratulations!!!!

Prof Karuna Sampath, University of Warwick, is visiting us today - Alfred Denny Conference room, 1pm: "Identifying the mechanisms governing extra-embryonic yolk syncytial layer development" Hosted by @iansudbery.bsky.social

Last week to apply for our PhD @mcb-sheffield.bsky.social

Congratulations to Haya on passing her PhD viva. Here is our #weareinternational wall - thesis titles in the student native language! 🇸🇦 for Haya

Unique opportunity to join the CytoMorpho Lab (in Paris ❤️) as a postdoc to work on the self-organization and polarization of reconstituted networks made of microtubules, motors and actin filaments in vitro. Experience required. Please Repost 🙏 thanks !

Prof Aga Gambus (agagambus.bsky.social) will be our external seminar speaker today - looking forward to hear her work on 'The novel replication initiation factor, DONSON: function, structure and regulation'. 1pm, Alfred Denny Conference Room. Sponsored by @merckgroup.bsky.social