How do epithelial cells integrate mechanical and biochemical signals to control their behavior? I am @ronjahoutekamer.bsky.social, and in this thread, I’ll show you how force transduction connects to biochemical signaling, and how it activates ERK by inducing biochemical ligand shedding.

Another brilliant Sheffield Pancreatic Cancer Research Network meeting. We heard two fantastic researchers working at the cutting edge of PC. Samrein Ahmed (SHU) shared mechanistic insights into RLIP76, and Helen Matthews (UoS) explored adhesion-dependent resistance to KRAS inhibition.

It was a huge honour to be able to present my PhD work recently at #DynamicCellVI ☺️ @bscb-official.bsky.social @biochemsoc.bsky.social thank you for having me and thank you for an incredible conference!

Fantastic talk by Rachel @rlawson954.bsky.social presenting her PhD work on keratins in mitosis at @bscb-official.bsky.social @biochemsoc.bsky.social #DynamicCellVI 👏👏👏 @mcb-sheffield.bsky.social

Wishing everyone a bright and happy Deepavali!

New release of #BigTrace plugin is out. Together with @aafkegros.bsky.social from Simone Köhler group we added a fully automatic tracing mode. + more macro functions and bug fixes github.com/ekatrukha/Bi...

🔔🧪 Call for Papers – #Mechanobiology of the #ExtracellularMatrix 🧬🛠️ Excited to serve as Guest Editor — together with Jacopo di Russo and Jennifer Young — of a new 𝐧𝐩𝐣 𝐁𝐢𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐏𝐡𝐲𝐬𝐢𝐜𝐬 𝐚𝐧𝐝 𝐌𝐞𝐜𝐡𝐚𝐧𝐢𝐜𝐬 Collection on “Mechanobiology of the ECM”. Deadline: 14 May 2026! www.nature.com/collections/...

Now in @natnano.nature.com: We need to acknowledge that - as with all new tech - AI also poses hazards we need to be aware of. Thanks @besfordgroup.bsky.social (Quinn A. Besford 🇦🇺🇩🇪🇺🇦) for leading this effort. www.nature.com/articles/s41...

Is your red the same as my red?

Thank you so much for this incredible opportunity at an incredible institution!!

Still blown away that I’m getting the chance to be here in Singapore for the MBI Mechanobiology conference, and not only that but also having the chance to present my #PhD work as a talk. Incredible opportunity and getting also to hear about amazing research from around the world 🌍 #mechanobiology

Have you ever thought about inflating tissues? Or maybe quickly deflating those inflated tissues? New #EpithelialMechanics pre-print: doi.org/10.1101/2025... 🧵 with pressure control, multiscale buckling, controlled wrinkling

Great talks by PhD students @isabelladavis00.bsky.social and Meg at the Sheffield Pancreatic Cancer Research Network meeting 👏

A beautiful day in the sunshine for our lovely lab summer social ☀️ @isabelladavis00.bsky.social @helenkmatthews.bsky.social @rlawson954.bsky.social

Had a great time at Physics Within The Cell hosted by the IOP today, and it was such an honour to share my work on epithelial division mechanics there ☺️ Thank you! @instituteofphysics.bsky.social #biomechanics #mitosis #phdlife #conferences

Must say I’m very proud of the start I’ve made to thesis writing #phdthesis #thesiswriting #phdlife

Happy to publish this News & Views article highlighting exciting new work from Rod Bremner's lab that shows that cell populations with a short cell cycle are intrinsically more susceptible to forming tumours

Neuroscientists have identified a brain signal in mice that kick-starts the process of overwriting fearful memories once danger is passed — a process known as fear extinction. https://go.nature.com/3REKSZb

Acceptable image-editing practices are partly a matter of common sense. But researchers say journals and funders could help scientists by standardizing policies. https://go.nature.com/437FWT6

Less than two weeks to go! Thanks for all the donations! www.justgiving.com/team/thalia

It took an extension to the extension of the extension, but after more than 3 years of negotiations, governments around the globe—but notably, not the United States—have finally agreed on a treaty to improve how the world prevents, prepares for, and responds to future pandemics. scim.ag/4lDYcLe

Great to hear about the research going on in @mcb-sheffield.bsky.social at University of Sheffield. Short talks from @helenkmatthews.bsky.social and @erainerolab.bsky.social about the projects going on in their labs 😊

Scientists identify key protein driving ovarian cancer spread @mcb-sheffield.bsky.social www.sheffield.ac.uk/biosciences/...

Excited to share that our latest paper is out today!!! 'The protease ADAMTS5 controls ovarian cancer cell invasion, downstream of Rab25' - great effort by Sherry and Rachele (1/6) @febsj.bsky.social @mcb-sheffield.bsky.social febs.onlinelibrary.wiley.com/doi/full/10....

Happy Caturday to all those science cats helping their owners with their research 😂☺️ #caturday #sciencecats #phdlife #biology

Meanwhile in Harrogate... Rachel & Bella from the lab are presenting at @physicsoflifeuk.bsky.social #physicsoflife2025

Congratulations to Bella for winning a poster prize at @physicsoflifeuk.bsky.social 2025 👏👏👏🎉🎉 #proudPI @mcb-sheffield.bsky.social