We are very happy to share our new PrePrint: Myosin VI orchestrates estrogen-driven gene expression in breast cancer cells. www.biorxiv.org/content/10.1... We characterise how Myosin VI is a key regulator of the Estrogen Receptor. Perturbation of Myosin VI impedes ER functionality.

Are you an independently funded fellow or lecturer within three years of your appointment? Join our webinar on 8 December to find out more about the Crucible Programme which is designed to transform your approach to research and collaboration. Book your place: whiterose.ac.uk/event/transf...

Join us in Sheffield! We are keen to support early career researchers in applying for independent research fellowships (IRFs) to join our friendly and collaborative environment, in areas related to developmental biology, stem cells and regenerative biology, and neuroscience.

EXTENDED DEADLINE: the deadline for BSCB medal nominations is now 14th November. 🔬Hooke Medal 👩‍🔬Women in Cell Biology medal 🧫 Postdoctoral Researcher medal 🔬Raff PhD medal award Details of eligibility and how to nominate are on our website.

Looking forward to this!

📢 Fully-funded 4-year MRC DiMeN PhD opportunity in our lab. 🔬 Exciting cancer cell biology collab with @maiblab.bsky.social & Liz Smythe @mcb-sheffield.bsky.social to use recombinant biosensors to image active KRAS in #pancreaticcancer 👇Apply by 4th Dec www.findaphd.com/phds/project...

Great talk from Rob de Bruin @lmcb-ucl.bsky.social yesterday. Made us rethink some of our cell cycle data. Thanks to PhD student @isabelladavis00.bsky.social for inviting Rob

Another fantastic set of talks at the 7th Sheffield Pancreatic Cancer Research Interest Network. A big thank you to Stephen Bradley and Ifeoluwa Oyelade for sharing their inspiring research. #PancreaticCancer #CancerResearch

🗓️ the deadline for our medal nominations is fast approaching! Send your nominations by 1st Nov For full details see bscb.org

How do cells adapt their volumes when they proliferate and form a multicellular mass in 3D? If you have wondered about this or work with 3D in-vitro systems, then you will be happy to read our paper now on bioRxiv! www.biorxiv.org/content/10.1... See the thread 🧵 below for more information.

Register for the Dynamic Cell VI conference, Reading, UK, April 2026! This conference focusses on all aspects of cell dynamics, co-organised by @bscb-official.bsky.social and @biochemsoc.bsky.social with @royalmicrosoc.bsky.social and the Chinese Society for Cell Biology. bit.ly/Dynamic-Cell-VI

Amazing talk by Bella, from @helenkmatthews.bsky.social lab at #NECB2025

PhD students @isabelladavis00.bsky.social and @zhebao.bsky.social doing a great job representing @mcb-sheffield.bsky.social at the Crick Cancer Conference this week

Very sad news that Jochen Guck has died. A true pioneer of biophysics, he was an inspiration to me and so many others.

Do you know an outstanding cell biologist? Nominations are open for our 2026 medals: 🔬Hooke Medal for outstanding contribution in cell biology 👩‍🔬Women in Cell Biology medal 🧫 Postdoctoral Researcher medal 🔬Raff PhD medal award Deadline 1st November

@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer. Deadline 15th October. Get in touch if you have any questions. Please repost! More details: www.imperial.ac.uk/jobs/search-...

Well done Bella 👏👏👏 #NECB2025 #proudPI

Great talks this morning from all the @mcb-sheffield.bsky.social final year students including from our very own Rachel and Meg. It's amazing to see how all the projects have developed.

Less than a week to go, before the North England Cell Biology Forum in Liverpool #NECB-2025 We’re excited to be welcoming cell biologists, from across the North, to our amazing city. The schedule is packed full of great science! bit.ly/3Vh5dpg

Studying cancer evolution needs multi-region or single cell seq for phylogenetics, right? Amazingly (I think!) we found single-sample bulk methylation suffices, via analysis of "fluctuating methylation". In @nature.com today led by brilliant @calumgabbutt.bsky.social www.nature.com/articles/s41...

Well done to our PhD student @rlawson954.bsky.social 👏 on giving a talk on her data on keratins and mitotic mechanics at the MBI-MPG conference at @mbisg.bsky.social in Singapore! @mcb-sheffield.bsky.social

Our new collection offers cell biologists practical, expert-driven guidance and best practices in the design, execution, and analysis of experiments, and the subsequent communication of their results to their peers. 👉 rupress.org/jcb/collecti... #Reproducibility

Sad to say goodbye to our brilliant mRes student Alessia Atzori. Alessia has done fantastic work on the transcription factors that control cell motility (watch this space for future publications) and is heading to Newcastle for a PhD

We are sponsoring the North of England Cell Biology Forum in Liverpool on 18th Sept Register and submit your abstracts here: markmorgan60.wixsite.com/necb2025

Interested in #mechanobiology of the cell nucleus? The submission deadline for the first ever FASEB Science Research Conference on the Mechanobiology of the Nucleus is August 31, 2025. Submit your abstract to be considered for a platform presentation. #MBNSRC events.faseb.org/event/Mechan...

Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️

Great talks by PhD students @isabelladavis00.bsky.social and Meg at the Sheffield Pancreatic Cancer Research Network meeting 👏

A beautiful day in the sunshine for our lovely lab summer social ☀️ @isabelladavis00.bsky.social @helenkmatthews.bsky.social @rlawson954.bsky.social

Fantastic lab hike with @erainerolab.bsky.social yesterday. Included a much needed ice cream stop at Chatsworth House (bakewell tart flavoured ice cream 😋) @mcb-sheffield.bsky.social

Excited to be selected as a Social Media Contributor for Small G proteins in cellular signalling and disease 2025! 🧬 Follow along for insights into how these tiny but mighty proteins shape health and disease! #BiochemEvent @BiochemSoc #SmallGProteins #CellBiology #SciComm

Registration is now OPEN for the UK Physics of Life Summer School 2025 – 8–11 Sept at Durham University! 🔗 Book now: pay.durham.ac.uk/event-durham... ℹ️ Info & programme: www.physicsoflife.org.uk/summer-schoo... Wellcome Travel bursaries are available for LMICs

Are you looking for a postdoc? I will be looking for 2-4 people after the summer to join the lab !! Do not hesitate to reach out and disseminate !!

Everyone in the lab is raving about Cellpose-SAM. Segmenting the previously unsegmentable across a range of different cell types and markers.

I am excited to share our new Sheffield Pancreatic Cancer Research Network website! Please check it out at... sites.google.com/sheffield.ac... @fohsheffield.bsky.social @mcb-sheffield.bsky.social

Had a great time at Physics Within The Cell hosted by the IOP today, and it was such an honour to share my work on epithelial division mechanics there ☺️ Thank you! @instituteofphysics.bsky.social #biomechanics #mitosis #phdlife #conferences

Today’s speaker in our DRN external seminar series (joint with MCB @mcb-sheffield.bsky.social) is Dr Giulia Paci @giuliapaci.bsky.social from UCL @ucl.ac.uk Giulia is a biophysicist interested in mechanics and developmental patterning. Host: Helen Matthews @helenkmatthews.bsky.social All welcome!

Looking forward to Vicky's talk today! Thanks to our postdoc @vichart33.bsky.social for hosting

Join us in Singapore in September for the "Mechanobiology in Time and Space" meeting hosted by the Mechanobiology Institute at NUS @mbisg.bsky.social and Max Planck Society @maxplanck.de. Abstracts due soon! www.mbi.nus.edu.sg/events/mbico...

We are sponsoring the first UK cell motility club on 13th June in Cambridge. Lots of slots for ECR presentations. It's not too late to submit an abstract!

new out in Nature www.nature.com/articles/s41...

A new role for mitotic shape changes! Mitotic rounding (or lack of) during division can control the segregation of cell fate determinants and therefore daughter cell state

Happy to publish this News & Views article highlighting exciting new work from Rod Bremner's lab that shows that cell populations with a short cell cycle are intrinsically more susceptible to forming tumours

Great to hear about the research going on in @mcb-sheffield.bsky.social at University of Sheffield. Short talks from @helenkmatthews.bsky.social and @erainerolab.bsky.social about the projects going on in their labs 😊

I have a 1 year fellowship available (MSc level) for someone interested in studying how nuclear mechanics regulates the timing of mitotic entry. Plus it´s in the beautiful city of Porto! Please spread the word to anyone who might be interested. dozer.i3s.up.pt/applicationm...

Enjoyed this April Fools joke in my son's Phoenix Comic this morning @phoenixcomics.bsky.social

Back in Sheffield and excited to play with an exciting new bit of kit - our new @lumicks.bsky.social c-trap optical tweezers with @mattdnewton.bsky.social @insigneoinstitute.bsky.social @mcb-sheffield.bsky.social

Congratulations to Bella for winning a poster prize at @physicsoflifeuk.bsky.social 2025 👏👏👏🎉🎉 #proudPI @mcb-sheffield.bsky.social

Meanwhile in Harrogate... Rachel & Bella from the lab are presenting at @physicsoflifeuk.bsky.social #physicsoflife2025

@vichart33.bsky.social and Meg representing the lab at @bscb-official.bsky.social @biologists.bsky.social #biologists100 @mcb-sheffield.bsky.social

Ewa Paluch kicks off the mechanobiology session at #biologists100