BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

We are delighted to be offering summer placements in 2026 with #In2research Learn more about the programme and application process at their information session next week - Monday 15 September 👉Register for the session here: ow.ly/VNg750WP8bf

Super proud to see our work featured on the cover of @emboreports.org today. Many thanks to @pedromics.bsky.social for this beautiful interpretation and depiction of our story. Read the associated paper here: www.embopress.org/doi/full/10....

RESEARCH | @simonsterson.bsky.social‬ @katajistolab.bsky.social‬ et al. Intestinal stem cells enriched for old mitochondria have enhanced ability to regenerate the epithelial niche 🧪 https://bit.ly/3HwPkb3 ?utm_source=bluesky&utm_medium=social&utm_campaign=natmetab

🧪🧪🧪 To the science feed you go... #neutrophils #metabolism #metastasis #BBCRadioScotland #GoodMorningScotland

It was a pleasure to speak to Lucy Whyte this morning on #BBCRadioScotland to discuss our recent @emboreports.org publication which has discovered how #neutrophil #metabolism facilitates #metastasis. Catch up with interview here: www.youtube.com/watch?v=tUUw...

🧪To the science feed you go... if you like #neutrophil #metabolism #metastasis #UPP1 #Uracil #fibronectin, then you are in for a treat 👇

Delighted to share that our work “Uridine Phosphorylase-1 supports metastasis by altering immune and extracellular matrix landscapes” was published today in @emboreports.org, describing how neutrophil metabolism influences niche priming to support metastasis (1/14) www.embopress.org/doi/full/10....

- A postdoc to work on cancer extravasation (4-year project). - A postdoc help in completing Filopodia-related lab projects (2-year). - Multiple Marie Curie postdoc positions that will open in the fall. - We will open a 5-year position to cover my teaching (70% research and 30% teaching).

It was a pleasure to visit @sheffielduni.bsky.social last week presenting our work "Neutrophil metabolism faciliates metastasis by influencing immune & ECM landscapes" at @mcb-sheffield.bsky.social seminar series.Thanks @erainerolab.bsky.social for the invitation & all who made it a memorable visit

We are SO EXCITED to share our story @nature.com: 🧵1/ Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring. This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease. 👉 Read here: rdcu.be/erD3b

Good morning, all. Science keeps making excellent progress. Check the curated summary of papers in #cancermetabolism and #mitochondrialbiology here: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading The boundary to what we can accept is the boundary to our freedom. Tara Brach

1/ Beyond thrilled to see my #PhD work now published in @jcb.org A short thread (🧵) for #metastasis #metabolism #ExtracellularVesicles (EVs) aficionados

@gounismichalis.bsky.social‬ et al. show that cells that seed early lung #metastasis in #BreastCancer have altered #metabolism. These metabolic alterations lead them to release extracellular vesicles which engender a microenvironment conducive to invasive growth. rupress.org/jcb/article/...

Delighted to share the work of @gounismichalis.bsky.social describing how metabolic reprogramming of micrometastatic cells influences EV release to generate invasive microenvironments.Michalis is an immense talent & it really is an honour to share his PhD work & my first senior author paper #ProudPI

New paper from @ivaskalab.bsky.social out now! 🍾 Watch how cancer cell adhesion dynamics are disrupted by inhibiting the phosphatase Shp2 - key to integrin β1 phosphorylation. Blocking Shp2 impairs adhesion and reduces invasion potential. 🎥👇 Read more at: www.nature.com/articles/s41...

Our newest paper is out in NCB. @jrwconway.bsky.social‬ designed a new FRET reporter, Illusia, to show the importance of integrin β1 phosphorylation dynamics in 3D invasion! Video: TNBC cells expressing Illusia with a Src (Saracatinib) or SHP2 (SHP099) inhibitor. www.nature.com/articles/s41...

Metabolic reprogramming of interleukin-17-producing γδ T cells promotes ACC1-mediated de novo lipogenesis under psoriatic conditions #gdTcells @natmetabolism.nature.com

Honored to have been elected with Patrick Caswell @mcrcellmatrix.bsky.social co-chair of the 2029 Gordon Research Conference on Fibronectin, Integrins, and Related Molecules! We have big shoes to fill: www.grc.org/fibronectin-..., but are up for the challenge!

Now online! m6A alters ribosome dynamics to initiate mRNA degradation

New paper from the lab! Want to know if there is a difference in ribosome collisions between your samples? We show that you can detect this in the rRNA reads in your ribosome profiling data. academic.oup.com/nargab/artic...

@aseica.bsky.social young members do not miss this amazing conference for early researchers from the @helloeacr.bsky.social

Happy to share our Tensin 1 phase separation project is now on bioRxiv. www.biorxiv.org/content/10.1... This wouldn't be possible without @johannaivaska.bsky.social @ivaskalab.bsky.social #VattulainenLab #MSCA by @ec.europa.eu @turkubioscience.bsky.social @inflames-flagship.bsky.social

New preprint alert!📣 @midibu.bsky.social and team take a deep dive into Tensin1 liquid-liquid phase separation (LLPS) and the mechanisms of how it regulates adhesion dynamics! Check out the preprint here: www.biorxiv.org/content/10.1... @johannaivaska.bsky.social

Not long after I started my lab, a prominent scientist told me it was “impossible” to be a successful PI and a mother Don’t ever let the naysayers tell you it can’t be done - of course it can! #HappyMothersDay this weekend to all the amazing scientist mamas raising their wonderful kids 🥰

What a great week at the #Fibronectin, #Integrins & related molecules #GRC. Inspiring and interesting talks, and the opportunity to speak to so many amazing people in the field. Really hope to be able to join you all again in 2027

A new study co-led by GCI member @hannahgarner.bsky.social showed how #neutrophil precursors receive signals from mammary tumours and promote #metastasis. Incredible collaboration with @nkinl.bsky.social, Monreno Martinovic, Karin de Visser and @dewitlab.bsky.social. Details: tinyurl.com/4c2snae6...

Beautiful study from @hannahgarner.bsky.social describing the role of immunosuppressive neutrophils in metastasis. Exciting to see #Upp1 prominantly in this data, given our recent manuscript describing a role for #neutrophil #upp1 in niche priming & metastasis www.biorxiv.org/content/10.1...

A wonderful setting to talk all things Fibronectin, Integrin & Related Molecules related this week. Looking forward to sharing our work, showing that neutrophil metabolism influences metastasis through integrin dependent effects on immune and ECM landscapes - poster Mon/Tues & talk Wed 7:45pm! #GRC

Recently, I've had the unique opportunity to visit prisons & teach incarcerated learners about cancer metabolism. This programme, Cell to Cell @celltocellscot.bsky.social, allows us to attend the Education Department of prisons within Scotland to...(1/4)

🚨 New preprint available! Third and final in the #CRISPR screen series!🚨 👉🏻 Uridine-sensitized screening identifies genes and metabolic regulators of #nucleotide synthesis www.biorxiv.org/content/10.1... By A. Strefeler in collaboration with Dave Pagliarini and team. @DIB_UNIL @FBM_UNIL 🧵 1/9

Many thanks to @cancerresearchuk.org for inviting me to speak at the Women of Influence meeting. It was a privilege to share my research with such a diverse and inspiring audience, and an honour to describe the positive impacts my amazing mentor, Kate Banks, has had on my development #CRUKWoI 🧪

Last week I had the pleasure of hosting @johannajoyce.bsky.social at @cruk-si.bsky.social. Johanna gave an inspiring talk on the importance of the local microenvironment in cancer & in science, a captivating talk describing amazing science & an impactful assessment of inequity in the workplace 🧪

Giving thanks for all amazing and inspiring women around the world on International Women’s Day We will never give up fighting for equality, for what is just and fair, and for each other 💪 #WomenOfTheWorldUnite #WomenInScience 🧪

On #IWD2025 I express thanks to all the women that inspire me, those that support me, & those that advocate for all of us.It's also a time for reflection & whilst there is a shift to accepting issues of gender inequality in STEM, actions to address these problems are still lacking #AccelerateAction🧪

💡 What I love most about my work in science is: discovery & generation of new knowledge, in addition to supporting people to achieve their goals & be the best versions of themselves 👩‍🔬I nominate @ppcenteno.bsky.social, @erainerolab.bsky.social & @johannaivaska.bsky.social #IWD2025 #AccelerateAction🧪

It's been a great year for #WomeninScience books - incl. the challenges faced, and the ways we can overcome historic imbalances & obstacles - as a community 🙌 Highly recommended reads by these authors 🤩 Katalin Kariko @athenedonald.bsky.social @lisampmunoz.bsky.social Kate Zernike #WomeninSTEM 🧪

Today is #InternationalDayOfWomenAndGirlsInScience. Women continue to face systemic barriers & biases in pursuing scientific careers. Closing the gender gap requires breaking stereotypes,promoting role models & supporting womens advancement through actions that promote inclusion,diversity & equity 🧪

Super interesting, looking forward to reading this 👇

Inspiring talks, amazing opportunities to present your science and network with leaders in the field. Hosted in the Science Centre this year, I'm excited to see all of this on the biggest IMAX screen in Scotland! Not to mention the ceilidh in Kelvingrove Art Gallery & Museum. Register now 👇 🧪

Today is #WorldCancerDay, raising awareness of cancer to encourage actions to aid prevention, diagnosis & treatment. As a cancer researcher, I am extraordinarily grateful to supporters & charities that support our work. To loved ones going through this right now,you are amazing & I am proud of you

Interesting study this, showing epigenetic memory within adipocytes. I know people will extrapolate all sorts from dieting, propensity to gain weight, etc... but on clinical level, biggest takeaway for me is the importance to prevent development of obesity in the first place. #epigenetics #MedSky

Exciting results from new CMBR paper describing anti-obesity drug that doesn't target GLP-1R... Press release and paper: cbmr.ku.dk/news/2024/ne... www.nature.com/articles/s41...

Inspired by the other amazing starter packs - here's one for cancer researchers! I tried to make this broad - from immunology to genomics to cell biology and so much more.. This list also includes organizations & institutes supporting cancer researchers 🧪🔬⚕️🩺 Hope its useful! go.bsky.app/FEoaJMc

Intro post! As an ECR @cruk-si.bsky.social my work has described a role for neutrophil metabolism in niche priming & metastasis. I am now pursuing opportunities to establish my own group to understand how immunometabolism primes niches in high-risk cancer diseases to inform prevention interventions