Miranda Hunter
@mrndhntr.bsky.social
📤 758
📥 373
📝 16
Cancer cell biologist @ MSKCC / NCI K99 fellow / 🇨🇦 in NYC
pinned post!
My recent postdoctoral work is out today in
@nature.com
! We found that physical confinement makes melanoma cells more invasive and drug tolerant. Thanks to all who made this work possible
@whitefishlab.bsky.social
@mskcancercenter.bsky.social
#NIH
#NCI
www.nature.com/articles/s41...
loading . . .
Mechanical confinement governs phenotypic plasticity in melanoma - Nature
Mechanical confinement of cancer cells at the tumour–microenvironment interface induces phenotype switching through chromatin remodelling by HMGB2, leading to a more invasive and drug-resistant state ...
https://www.nature.com/articles/s41586-025-09445-6
5 months ago
6
69
25
Looking forward to another year’s Cell Bio meeting next week in Philly. I am co-chairing a cancer cell biology minisymposium on Tuesday morning with Partha Roy and my pal Junior West
@jr2255.bsky.social
. Lots of great talks about imaging tumor-TME cell interactions!
#cellbio2025
about 2 months ago
0
5
3
Couldn't agree more - the Biorender-ification of science illustration is so depressing.
add a skeleton here at some point
about 2 months ago
0
5
0
Go Jays!!!!!
add a skeleton here at some point
4 months ago
0
1
0
Thank you to Cancer Discovery
@aacrjournals.bsky.social
for highlighting our recent paper!
aacrjournals.org/cdnews/news/...
loading . . .
The Mechanical Microenvironment Drives Plasticity in Melanoma
Major Finding: Mechanical confinement governs phenotype switching from a proliferative to an invasive state. Concept: Stable changes in chromatin architecture in mechanically confined cells induce can...
https://aacrjournals.org/cdnews/news/2705/The-Mechanical-Microenvironment-Drives-Plasticity
4 months ago
0
5
0
reposted by
Miranda Hunter
Oded Rechavi
4 months ago
Got to love studies that were clearly conducted "for the love of the game" (“self-decapitating sea slugs”, “plants that see and use that for mimicry”, “worms that jump in the air”, aka papers you sometimes find in
@currentbiology.bsky.social
) References to all of this bellow👇
3
72
14
reposted by
Miranda Hunter
Roxane Gay
5 months ago
I can't believe I need to have an AI policy! I made it pretty short though: Using AI is cheating, yourself mostly. In addition to the environmental blight created by AI, it makes no sense to use it in your intellectual and creative work. Why would you outsource your innate intelligence?
18
1386
234
Lay(-ish) summary of our melanoma confinement paper with some behind the scenes details of how this project came about, and what we’re planning to do next (hint: PDAC 🐟). Thanks
@nature.com
for featuring our work.
add a skeleton here at some point
5 months ago
0
9
1
My recent postdoctoral work is out today in
@nature.com
! We found that physical confinement makes melanoma cells more invasive and drug tolerant. Thanks to all who made this work possible
@whitefishlab.bsky.social
@mskcancercenter.bsky.social
#NIH
#NCI
www.nature.com/articles/s41...
loading . . .
Mechanical confinement governs phenotypic plasticity in melanoma - Nature
Mechanical confinement of cancer cells at the tumour–microenvironment interface induces phenotype switching through chromatin remodelling by HMGB2, leading to a more invasive and drug-resistant state ...
https://www.nature.com/articles/s41586-025-09445-6
5 months ago
6
69
25
reposted by
Miranda Hunter
Itai Yanai
5 months ago
Science is fun, but Academia.. needs work
0
89
14
reposted by
Miranda Hunter
Felix Gunawan (he/him) 🇨🇦🇩🇪🏳️🌈
7 months ago
1/6 Thrilled to share that I have joined the Department of Cell & Systems Biology at the University of Toronto as an Assistant Professor! Grateful for the journey so far and incredibly excited for what’s ahead at
@uoftcellsysbiol.bsky.social
@utoronto.ca
.
csb.utoronto.ca/faculty/feli...
3
28
10
reposted by
Miranda Hunter
Faine Greenwood
7 months ago
it is hard to convey in words how bad the bloodbath has been for professionals working in the "not evil" sectors
add a skeleton here at some point
17
838
176
reposted by
Miranda Hunter
Brad Wouters 🇨🇦
9 months ago
It's time for Canada to Lead
www.theglobeandmail.com/opinion/arti...
loading . . .
Opinion: Canada can be the global leader in medical research
As the U.S. slashes funding to its research initiatives, there is a chance for us to recruit the best talent from around the world
https://www.theglobeandmail.com/opinion/article-canada-can-be-the-global-leader-in-medical-research/
0
15
8
Very smart move. Vancouver is gorgeous and UBC is great. Apply!!
add a skeleton here at some point
10 months ago
0
4
2
reposted by
Miranda Hunter
Thibaut Brunet
10 months ago
Striking new study from
@archaeon-alex.bsky.social
's lab just out in
@science.org
on multicellular development induced by compression in Archaea:
www.science.org/doi/10.1126/...
loading . . .
Tissue-like multicellular development triggered by mechanical compression in archaea
The advent of clonal multicellularity is a critical evolutionary milestone, seen often in eukaryotes, rarely in bacteria, and only once in archaea. We show that uniaxial compression induces clonal mul...
https://www.science.org/doi/10.1126/science.adu0047
6
345
148
Great ❤️
add a skeleton here at some point
10 months ago
0
1
0
reposted by
Miranda Hunter
Steve Schwinghamer🇨🇦
11 months ago
Hey! Are you an American considering a PhD or a postdoc, and the funding / academic situation just went absolutely bonkers? Canada's federal funding awards just added eligibility for international applicants if at Cdn institutions.
www.nserc-crsng.gc.ca/NewsDetail-D...
loading . . .
NSERC - Latest News - Launch of the new Harmonized Tri-agency Scholarship and Fellowship programs
As announced in Budget 2024, the scholarship and fellowship programs administered by the three federal research funding agencies – the Canadian Institutes of Health Research (CIHR), the Natural Sciences and Engineering Research Council (NSERC), and the Social Sciences and Humanities Research Council (SSHRC) – have been streamlined into a new harmonized talent program called the Canada Research Training Awards Suite (CRTAS) that will open for applications in summer 2025.
https://www.nserc-crsng.gc.ca/NewsDetail-DetailNouvelles_eng.asp?ID=1518
23
1019
507
reposted by
Miranda Hunter
Jeremy Berg
11 months ago
Second, women make terrific leaders. They tend to be organized and prepared. They also tend to be more empathic as they have often experienced more challenges and setbacks than men in similar positions. They tend to be more courageous, particularly when the stakes are high. 36/n
1
133
22
reposted by
Miranda Hunter
American Society for Cell Biology
12 months ago
NIH-funded research is at risk. Cuts to federal funding could harm science and the economy. Contact Congress now to protect research. Every call matters. Find your reps at
govtrack.us
and speak up today.
#FundScience
www.ascb.org/science-poli...
0
51
38
reposted by
Miranda Hunter
Tyler Huycke
about 1 year ago
Super excited to announce my new lab at the University of Michigan opening Jan 2025! 🎉We’ll study how cells work together to shape the GI tract, with ties to regeneration & disease. Hiring at all levels—esp. a research tech to help launch the lab! Info:
huyckelab.org
#DevBio
#CellBio
#Hiring
12
83
23
Fun catching up with some fellow RFG lab OGs in San Diego for
#cellbio2024
!
@rodrigofg.bsky.social
about 1 year ago
0
7
1
you reached the end!!
feeds!
log in