Congrats to Laura Pala and Hiran Prag on their new paper in Cardiovascular Research. doi.org/10.1093/cvr/...

Congrats to Patrick Cardwell on his paper that covers his PhD work - another great collaboration with the Richard Hartley lab. doi.org/10.1016/j.ej...

Congrats to Dunja on her latest paper just out in Nature Cardiovascular Research! doi.org/10.1038/s441...

At Keystone enjoying some mitochondrial science and catching up with friends www.keystonesymposia.org/conferences/...

Funding? I'm a simple academic, so I'll have to await someone smart to explain to me how "pausing" MRC and BBSRC funding is the action of a biomedical science superpower...?

Congrats to Jan whose new paper on persulfide measurement is is out now in Nature Comms

Christmas in the lab....

Huge congratulations to Abigail Giles whose paper has just come out in Nature Cardiovascular Research - from a great collaboration with Bob Balaban, along with Thomas Krieg and Tish Murphy. doi.org/10.1038/s441...

Congrats to Emma Yu on her new paper on Tafazzin! doi.org/10.1038/s414...

Pleased to be a small part of a recent paper led by Thiru Kanneganti at St Judes www.cell.com/cell/fulltex...

Congrats to Kath Hammond who was awarded a short talk prize at the recent WT "Mitochondrial medicine: therapeutic development" meeting at Hinxton.

Excited to share that at the annual MRC MBU symposium I was awarded best poster prize for my PhD project on Succinate Metabolism in Cardiac Ischemia/ Reperfusion Injury! Thanks to my lab, collaborators, and my PI Mike Murphy. @mitoredox.bsky.social

Drs Cherrie Kong and Stephen Harmer (University of Bristol) are offering a fully funded PhD project, " For information and to apply: www.findaphd.com/phds/project.... For information including application preparation: [email protected] Application deadline: 15 December 2025

Congrats to Nils Burger who is just starting his lab at UTSW in Texas! Any prospective PhD students or post-docs should get in touch with Nils. www.nils-burger-lab.com

In Toronto today giving a seminar at the Sick Kids Research Institute on "Mitochondria in Ischemia-Reperfusion Injury: From Basic Science to Potential Therapies" Great to catch up with previous lab member now in Toronto - Thomas Hurd, Ellen Robb and Anna Dare.

Great to see this paper out - another Krieg/Murphy collaboration - and congratulations to Jordan Lee who did most of the work! academic.oup.com/cardiovascre...

Great to see Hiran Prag setting up his lab at the University of Manchester - I'm expecting great things! personalpages.manchester.ac.uk/staff/hiran....

It was wonderful to see the NEJM paper today about healthy babies born free of mtDNA disease following mitochondrial donation. Built on decades of work led by Doug Turnbull and his team in Newcastle. www.nejm.org/doi/full/10....

It was a great pleasure to attend last week Professor Dunja Aksentijevic's inaugural Professorial Lecture at Queen Mary, University of London. Dunja, it's just the start!

Congrats to Helena Cocheme @cochemelab.bsky.social on her paper on redox regulation of autophagy in Drosophila. doi.org/10.1038/s414...

Good day yesterday at the William Harvey Research Institute Research Day where I was honoured to receive the Derek Willoughby Medal and give a lecture. Great hospitality from Dunja Aksentijevic and Sir Mark Caulfield.

Series of interesting papers showing that haematopoietic stem cells can undergo damaging clonal haematopoiesis when they acquire mutations that enhance mitochondrial respiration - opening the way to using metformin - and my beloved MitoQ - to prevent this transition. doi.org/10.1038/s415...

Congrats to Dunja Aksienijevic on her latest paper!

By the Atlantic in Galway at the SFRRI meeting - catching up with old friends and new. www.sfrrgalway2025.com

Congrats to Renata Goncalves who led a study in Gokhan Hotamisligil's lab that has just come out in Nature - ably assisted by Jillian Riveros! www.nature.com/articles/s41...

Congratulations to Abigail Giles who was awarded the "The Richard J. Bing Award for Young Investigators" at the recent World Congress of the International Society For Heart Research in Japan. Well done Abigail!

Congratulations to @clarebryant.bsky.social on her election to the Academy of Medical Sciences!

Congrats to Ana Vujic on her latest paper! journals.physiology.org/doi/abs/10.1...

Delighted to be a small part of this paper led by Alicia, Brian and Simon. doi.org/10.1038/s414...

Delighted that our work describing a potential novel treatment approach for B-cell Acute Lymphoblastic Leukaemia is published today in @natcomms.nature.com‬. 🧵 www.nature.com/articles/s41...

Pleased to have been elected a Member of Academia Europaea. Thanks to Mike Davies of Copenhagen for nominating me. www.ae-info.org/ae/Member/Mu...

IMS-MRL External Seminar (Cambridge) Tuesday 6 May 2025 at 13.15 Professor Mike Murphy, Understanding how mitochondria contribute to ischaemia-reperfusion injury HOST: Professor Steve O’Rahilly Hybrid Seminar in the IMS-MRL Seminar Rooms (for IMS staff), Online for others

At the University of Cordoba today giving a seminar in the department of Prof Raquel Requejo. She used to be post-doc in my lab in Cambridge and is now running her own lab. www.uco.es/dptos/bioqui...

Visiting IBIS in beautiful Sevilla www.ibis-sevilla.es/en/ Hosted by José López-Barneo - giving a seminar there today.

Important new paper in Nature from Gero Miesenböck's lab showing that the accumulation of lipid peroxidation products from mitochondrial ROS production leads in sleep. doi.org/10.1038/s415...

Congrats to Michal Minczuk @mitogene.bsky.social and all at Pretzel Therapeutics on initiation of their first Phase I trial! www.pretzeltx.com/pretzel-ther...

Well done to María Torres-López and José López-Barneo on this paper in FEBS Letts - seems that RET at complex I is not involved in carotid body oxygen sensing... doi.org/10.1002/1873...

Congrats to Kasparas Petkevicius on his paper just out in Science Advances - Andrew James in my lab played a key role - important implications for Battens Disease doi.org/10.1126/scia...

Great to see paper from Alva Casey out today in Nature Metabolism - from her PhD. Well done Alva! doi.org/10.1038/s422...

Glad to be a small part on this interesting paper from Milos Filipovic with actual work done by Jan Miljkovic and Alva Casey in my lab. Ergothioneine improves healthspan of aged animals by enhancing cGPDH activity through CSE-dependent persulfidation: Cell Metabolism www.cell.com/cell-metabol...

Regarding paper in Cell from Jessica Spinelli on rhodoquinone (RQ) in mammalian mitochondria. The implication is that the lower reduction potential will allow SDH to run to fumarate more easily under hypoxic conditions. The introduction of RQ in vivo was elegant and gave pharmacological effects.

Very interesting paper in Cell from Jessica Spinelli showing rhodoquinone (RQ) in mammalian mitochondria. www.cell.com/cell/fulltex...

The best lack all conviction, while the worst Are full of passionate intensity.

Hi All Moving to BlueSky from X - do I need to explain why? Thought not...