Crystal packing affects protein dynamics - super interesting!

Amazing work!!

On this day in 1184, this happened: Erfurt latrine disaster — en.wikipedia.org/wiki/Erfurt_...

Are you passionate about AI for molecular engineering? Just two weeks left to apply to the 2 PhD positions currently open in our team at Chalmers! 🎓 For details: ailab.bio/join-us

If you are interested in glycans e how they modulate the function of other biomolecules this is the CECAM meeting to be! Look at the lineup of speakers! And the location is also not too bad :P Registrations are open until 30/06/25 at www.cecam.org/workshop-det...

🚀 Zwei neue #Exzellenzcluster für die #GoetheUni! Mit @scale-cluster-ffm.bsky.social & @cpi-exstra.bsky.social wird Frankfurt ab 2026 zum Hotspot für Zell- & Gesundheitsforschung. Nächster Schritt: Exzellenzverbund @rheinmainunis.bsky.social mit @unimainz.bsky.social & @tuda.bsky.social.

🧬PSB Symposium on " #MachineLearning in Cellular #StructuralBiology ", EPN Campus Grenoble, France, 26-27 June 2025🧬 📢Reminder - Call for abstracts (posters & short talks) Submission & registration deadline 25 May: www.psb-grenoble.eu/psbsymposium... @esrf.fr @embl.org @illneutrons.bsky.social

Last days! 📆

Check out the speakers! @rommieamaro.bsky.social @jessicaandreani.bsky.social @gauravbhardwaj.bsky.social @bonomimax.bsky.social @rocovino.bsky.social @arneelof.bsky.social Sergei Grudinin @magistratolab.bsky.social Christine Orengo @joanampereira.bsky.social Maya Topf, Sameer Velankar, Basile Wicky

Been thinking about biomembranes? Wondering what next decade of research will be? Wonder no more: there's an awesome conference coming up in Copenhagen in July!! From simulations to cells and everything in between. 5 days left to submit abstract - APPLY! www.biophysics.org/blog/beyond-...

Presenting our work on minimum energy path generation between two states for physical systems at the FPI Workshop at @ICLR tomorrow! Scaling up to solvated BPTI and observing the same conformational changes as long reference MD with six orders fewer force field evals! Drop by!

We are recruiting a colleague to our division at Chalmers in Data-Driven Life Science (broadly defined), a competitive starting package is offered and you get to be part of a support, yet young and ambitious research environment. Apply here: www.chalmers.se/en/about-cha...

Counting particles could give wrong probabilities in Cryo-Electron Microscopy www.biorxiv.org/content/10.1101/2025.03.27.644168v1 #cryoem

Run BioEmu in Colab - just click "Runtime → Run all"! Our notebook uses ColabFold to generate MSAs, BioEmu to predict trajectories, and Foldseek to cluster conformations. Thanks @jjimenezluna.bsky.social for the help! 🌐 colab.research.google.com/github/sokry... 📄 www.biorxiv.org/content/10.1...

⏰ Two weeks left to register for our Benzon Symposium on Protein structure prediction and design 🧶🧬🖥️ Meeting will take place in Copenhagen 🇩🇰 on Sept. 1–4, 2025, and will feature an amazing list of speakers 👨‍🔬👩‍🔬👩‍💻👨‍💻 Submit your application via: benzon-foundation.dk/benzon-sympo...

On my way to #APS California!

CDU’s debt brake turns out to be a lot like my diet: spend many months telling everyone you meet that it’s tough but totally essential and completely inviolable, before just junking the whole thing whenever you feel like it

Please RT: If you are interested in doing your PhD at the ILL, Grenoble in collaboration with the Hennig-Lab at University of Bayreuth, Germany, look here: esrf.gestmax.eu/1874/1/phd-s...

Registration is now open for our Benzon Symposium on "Protein structure prediction and design" Meeting will take place in Copenhagen 🇩🇰 on Sept. 1–4, 2025, and will feature an amazing list of speakers Get your application in before March 31st via: benzon-foundation.dk/benzon-sympo...

Zelensky’s timeline right now is a thing of beauty

Geht’s raus und geht’s wählen! ⚽️🗳️

The BioEmu-1 model and inference code are now public under MIT license!!! Please go ahead, play with it and let us know if there are issues. github.com/microsoft/bi...

📢 New preprint, lead by Alex Bronstein, @sankethvedula.bsky.social and colleagues: Guiding AlphaFold with experimental data. This approach generates conformational ensembles guided by NMR, X-ray (or whatever) data. I am thrilled to tackle lots of exciting problems with it! arxiv.org/abs/2502.09372

Molecular dynamics requires a lot of expert knowledge to set-up and analyze simulations. We set out to automate it with LLM agents: MDCrow!

If you are interested in postdoctoral research on ligand-gated ion channels and the synapse, or simulation/AI methods for structural biology - drop me a line if you'll be around at Biophysical Society in LA! #bps2025 #bps #biophysics

ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬 The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy www.biorxiv.org/content/10.1...

It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density, which usually isn’t attainable. Lipid-CLEM brought to you by @mathilda95.bsky.social changes that. www.biorxiv.org/content/10.1...

Ooh nice preprint! Studying membrane nanodomains needs nanoscale lipid localization - current methods fall short. 'Lipid-CLEM', correlative light & EM with click chemistry to map lipids. In endosomes, it shows sphingomyelin’s differential partitioning beautifully. www.biorxiv.org/content/10.1...

A unique opportunity for the European research system (which we will, of course, not pick up)

👇Effective use of #AI tools for software development still requires deep domain knowledge and technical expertise Rather than replacing fundamental skills, #AI serves as a powerful accelerator for experienced developers who understand both the problem space and the capabilities of their tools

Ten simple rules for developing good reading habits during graduate school and beyond To me, the most important are: Read often, read broadly (incl. older papers and outside your field), and learn to read some papers in detail and others more superficially (and quickly)

Check out our new paper! Protein assembly in membranes is crucial yet elusive. Why steer when you can just observe? We introduce a bias-free simulation method that captures the full picture of transmembrane dimerization—free energies, mechanisms, and rates! pubs.acs.org/doi/10.1021/...

Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring www.science.org/content/arti...

Fed up with being asked about cryptozoological sightings I wrote about the impossibility of #Yeti, #Bigfoot and #Nessie the-european.eu/story-41724/.... Will I now be asked to comment on #alien sightings? Included is a photo of a #Yeti I took 😂. As a top scientist, @sykhalid.bsky.social, thoughts?

Slides for a general introduction to the use of Optimal Transport methods in learning, with an emphasis on diffusion models, flow matching, training 2 layers neural networks and deep transformers. speakerdeck.com/gpeyre/optim...

I was wondering the same, I get 20 a day of these silly emails and my spam filter doesn’t get better at blocking them

PhDs in biochemistry, structural biology, pharmacology, or similar, located in the US and with strong publication track records and a high motivation to solve Parkinson's, please send CV directly to me at [email protected]. Repost appreciated.

Check out my poster on 'Trajectory Level Langevin Dynamics' aka 'Simulations of simulations', using differentiable MD forcefields, at the 'ML and the Physical Sciences' Workshop @NeurIPS! Link: openreview.net/pdf?id=daEra...

#NeurIPS2024 check out our work: Cryo-EM images are intrinsically low dimensional at the MLSB workshop with Luke Evans, Octavian-Vlad Murad @larsdingeldein.bsky.social @rocovino.bsky.social & Marina Meila www.mlsb.io/papers_2024/...

Impressive work by @franknoe.bsky.social and team! A pragmatic tour-de-force combining experimental and predicted protein structures, MD simulations and experimental stability data to sample conformational ensembles of proteins. Think AlphaFold, but capturing multiple free energy minima.

Super excited to preprint our work on developing a Biomolecular Emulator (BioEmu): Scalable emulation of protein equilibrium ensembles with generative deep learning from @msftresearch.bsky.social ch AI for Science. www.biorxiv.org/content/10.1...

Another deep-learning approach to sample conformational ensembles of proteins: BioEmu, out of Microsoft Research. www.biorxiv.org/content/10.1...

Gotta love the tone of disappointment about myoglobin not having an elegant structure. Kendrew et al. (1958) www.nature.com/articles/181...

Hello! I'm posting this both here and on the X-rated site, let's see where it gets more re-posts 😇. We are looking for a research software engineer to help us develop (even) better code for #compchem #atomicscale #machinelearning. Check out the specs and apply! www.epfl.ch/labs/cosmo/i...

Academics in their forties

Join us at Freie Universität Berlin as Post-Doc in molecular simulation of chemical reactions. Dive into rare events, machine-learned force fields & dynamical reweighting. 4 years, 100% TV-L. More details: bcp.fu-berlin.de/en/chemie/ch... #CompChem #machinelearning #postdoc