Extraordinary. We've known for a while that JD Vance and the rest of the Trump admin all follow the same race-and-IQ obsessed weirdo freak accounts on twitter (like this eigenrobot loser), and that miasma of idiocy is what runs America now

UK Biobank data is being used here for blatant race pseudoscience by a white supremacist blogger, Jordan Lasker. @ukbiobank.bsky.social this looks to be a clear breach of terms and an unauthorised use the data, no?

Today is the birthday of one of my favorite scientists, thinkers, and writers of all time, Stephen Jay Gould. He would have been 84 year old. “Science is not a heartless pursuit of objective information; it is a creative human activity.” -S. J. Gould

I watched "Eddington" the other night, and Ari Aster has proven once again that he is the undefeated best writer-director of this generation

Hold on, I thought trying to retract papers for political reasons was only something "woke" mobs did? www.nature.com/articles/d41...

Lots to unpack here, but the main thing I want to comment on is the absurdity of it all. Science/academia in the U.S. is being rapidly destroyed by the Trump admin, but all that pales in comparison to "woke" peer review, amirite folks? Cc'ing: @caitlinmoriah.bsky.social

Important details about that new embryo selection company, its dubious scientific claims, plus its many affiliations with white nationalism 👇👇👇

Numerous FAQs & think pieces were written promising GWAS participants & the broader public that sociogenomics was focused on education improvement, environmental interventions, and away from the hereditarian past. All quickly betrayed.

Just stating the obvious: - academic jobs are super competitive, even with a good CV - Colin severely overstates how impressive his CV is (he doesn't know how to use R or Python) - Colin makes no mention of the fact he was in the middle of a massive scandal and has had many papers retracted

The New York Times Had To Work With A Eugenicist So They Didn’t Get Scooped By A Bigot @defector.com defector.com/the-new-york...

Really highlights how the world of the far-right is kinda like Plato's cave, but they're all in the cave voluntarily, and it's just them making shadow puppet shows for each other and getting scared

I've been MIA for a while, but it makes me happy to see everyone now hates this racist dipshit Jordan Lasker guy as much as I do. Some niche lore on Jordan: he's such a pathological liar that even other neo-Nazis eventually got sick of his bullshit: tgstat.com/channel/@TGH...

The Trump admin is terminating scientific grants under the pretence combating antisemitism. They are going to any use any pro-Palestinian activity on campus as an excuse to do this to all American universities, effectively killing science and free speech rights in one go

A while ago I decided to give up on maintaining my own Neovim config because I was just making a worse replica of LazyVim, so now I just use LazyVim and haven't looked back

Mature #HIV-1 contains >2000 copies of “spacer peptide 2”, but we didn’t know why. We now see that SP2 binds the matrix protein and triggers the change into its mature arrangement. Summary video from @margotriggi.bsky.social

As expected, the Royal Society does nothing like a bunch of cowards. Nazism, spreading lies, and destroying scientific institutions are A-OK according the Royal Society

It's finally official and verified: The X user "Cremieux" is ID'd as a guy called Jordan Lasker. Lasker has been LARPing as an expert in genetics on X to promote racist pseudoscience. @sashagusevposts.bsky.social has been calling out his bullshit for ages

The thing is, if you asked any of these people about the right-wing currently gutting science, they'd feebly say something about how it's the lefts fault. That or they simply don't care and they wanted science to die anyway, which is also likely. Also, Richard Dawkins fucking sucks lol

It matters that scientists speak out against what is being done to US science. Staying silent is neither "objective" nor "staying out of politics". Silence now *is* political - it supports the status quo, says "nothing to worry about". We need to sound the alarm. www.nature.com/articles/d41...

Wow! The DOGE feedback mechanism is working exactly as thus planned!!

Since the topic of "should science get involved in politics" has once again sprung up, here's Joseph Thornton talking about the Creationism effort to undermine scientific education, and how scientists initially tried not to get involved.

How are people STILL doing this? Look outside, the lunatics who believe science is a "woke cabal" are dismantling scientific institutions right now. Don't want science to be political? Ok, don't vote either, don't say anything, just lay down and get trod on. That's what Elon wants from you too!

Feels strange to be sharing great science papers at the moment, but I love this paper published late last year from Georg Hochberg's team: www.nature.com/articles/s41... Evolution consistently produces molecular "spandrels" with no functional benefit

NIH thankfully coming to.the realisation of "hey, if Trump isn't complying with the law, what if we just didn't comply with his "law" either?" popular.info/p/breaking-n...

btw, Jonathan Pallesen is yet another race science freak that has garnered favour from Elon Musk. He's published some pseudoscience on Jewish IQ polygenic scores www.theguardian.com/world/2024/j...

Sorry to be the bearer of bad news @veritasium.bsky.social, but there's a mistake in your new Youtube video:

Actually, yeah, I can believe that, because running research facilities is expensive. Do you realise how expensive it is to keep a single -80C freezer running? Musk frames this as him saving money for science, but in reality, he is single-handedly killing science in the US

Just watch all those pundits that cry "keep politics out of science" (whenever it's suggested that scientists shouldn't be passive in the face of bigotry and pseudoscience) stay absolutely silent about this clear case of a political ideology interfering with science

This sort of complaint about Bluesky is funny to me. Impact on society? Do you think scientists can improve society by... tweeting? Plus, I've never seen the academics who make these "Ivory Tower" complaints ever lead by example and engage with "dissenting opinions" themselves.

Good tips here. A couple of things I'd add that I've personally found helpful: 1) write down questions you have as you go 2) read the bibliography of a paper and follow up on citations that pique your interest. Usually more efficient than using Google Scholar to find relevant reading material

What limits rubisco function? Is it the chemical mechanism? Evolution? In this paper, @prywes.bsky.social et. al explore this question by assaying >99% of single amino acid mutants in Form II rubisco (1/7) doi.org/10.1038/s415...

Just to recap, Elon: - unbanned Nazis - follows and replies to numerous Nazi accounts - believes in Great Replacement theory - supports the AfD - did a Nazi salute in public, twice... but most media orgs won't call him what he is--a Nazi--because... idk, it's rude or something

Gotta say, it doesn't feel good that a few extremely powerful and evil billionaires are shaping the trajectory of history in terrible ways in front of our very eyes

A seminar on the history of protein structure prediction and protein design. By Mohammed AlQuraishi youtu.be/Ahwn-KS8fd0?...

Can there be any doubt anymore that Elon is a neo-Nazi? Like, come the fuck on.

Foldseek 10 with 4-27x (1-8 GPUs) faster search through MMseqs2-GPU. Faster ProstT5 protein search w/o structure prediction through multi-GPU/Apple Metal, new BFVD/BFMD databases and multimer clustering (preview). 💾 github.com/steineggerla... 📄 www.biorxiv.org/content/10.1... 🐍 available in bioconda

In a great collaboration with @hummerlab.bsky.social and the Kräusslich lab: HIV capsid doesn't break at the NPC; instead, it cracks open the NPC itself! Details in Cell: authors.elsevier.com/sd/article/S... @mpibp.bsky.social @uniheidelberg.bsky.social A thread below:

Really wish this naive and ahistorical definition of eugenics would die. Eugenics is not just coercive and authoritarian policies. It can come under the guise of benevolent incentives. It can be driven by non-state actors too, like with that Simone and Malcom Collins couple.

Elon has never once touched a command line in his entire life, has he?

Really bleak stuff. Meta will now allow all sorts of anti-LGBTQ speech on the platform as a matter of course. They will also allow racist speech if you supposedly claim your racism is "scientific". theintercept.com/2025/01/09/f...

After a decade in the oven🧑‍🍳, we’re happy to finally share our preprint on the in situ architecture of the ciliary base. 📜 https://dir.lat/41qAY4 We used #CryoET to resolve transition zone structures and reveal the stepwise assembly of IFT...

Looking for opinions: the work laptop options on offer at my uni are Dell XPS (Windows 11) or Macbook. Never used Mac, but tempted to give it a shot. My only requirements is that I need to have a Unix command-line and Powerpoint (never found a good open-source alternative of Powerpoint).

A scientific and rigorous method for checking the quality of a dataset according to race scientists is saying "it looks to be about right" cc: @rebeccasear.bsky.social

2025 will also be the year of the Bird account

Deep learning for proteins tutorial: github.com/Graylab/DL4P...

I'm not a huge fan of Jupyter notebooks and would prefer to work in the terminal + neovim. Found a neat solution with "matplotlib-backend-kitty", which shows matplotlib plots in directly in the terminal. Love it. github.com/jktr/matplot...

We're recreating this Borges story in real time

Cutest Christmas ornaments ever??

"... the forces of racism have regrouped on the borders of legitimate science and transformed themselves into a dynamic and creative citizen science movement capable of exploiting features of human genetics... human geneticists need to contend with the evolving practices of this ... movement"

Very excited to see this tool come out (and just before Christmas). I've been following it on Github and it looks incredible. "Unicore enables scalable and accurate phylogenetic reconstruction with structural core genes" 📝 www.biorxiv.org/content/10.1... 💾 github.com/steineggerla...