Construction of the new central station marks one of Stuttgart's most far-reaching transformations. The old terminus station is turned into a through station with all tracks underground, allowing for major urban development on the freed surface. #Stuttgart21 #Transit #UrbanDevelopment

Yesterday, six years after graduating, I gave a career talk for my PhD supervisor Gerhard Hummer's department. Joining their group retreat at the famous Harnack House in Berlin came with so much nostalgia and joyous reunions, but also cutting-edge science, new friends, and fabulous autumn weather!

My wife has volunteered at a local food bank for years and confirms what many of you have probably heard: in this case, straight cash is a good donation if you can do it. The food banks have better access and buying power than individuals do, and can try to address item imbalances as they see them.

📜 New preprint! We developed PoGö, an algorithm to optimize the essential dynamics of GöMartini proteins based on all-atom simulations: www.biorxiv.org/content/10.1...

The #Heuneburg was one of the most important Celtic centers in Central Europe until it was abandoned after a devastating fire in the 5th century BC. Today, an open air museum shows reconstructions of some of the houses and of parts of the fortification. #History #Archaeology #Museum

German waiters must love me because of how much I've internalized American tipping culture. 💸

Finally out: the most time- and memory-efficient way to cluster ultra-large molecular libraries! Preprint: lnkd.in/emkeU_NH Code: lnkd.in/euHc5s7U

Largest study of its kind shows AI assistants misrepresent news content 45% of the time – regardless of language or territory. www.bbc.co.uk/mediacentre/...

Autumn vibes in my hometown. 🍂 #Photography #Binzwangen #BadenWürttemberg #Germany

What if we did a single run and declared victory

Save the date! Next year's European #RDKit UGM will take place from 16-18 September in Darmstadt, Germany. Pre-registration will open in early 2026.

We (@sobuelow.bsky.social) developed AF-CALVADOS to integrate AlphaFold and CALVADOS to simulate flexible multidomain proteins at scale See preprint for: — Ensembles of >12000 full-length human proteins — Analysis of IDRs in >1500 TFs 📜 doi.org/10.1101/2025... 💾 github.com/KULL-Centre/...

The recorded videos are HERE! We've finally posted all the recorded talks from the Boston's Free Energy Workshop 2025. If you missed the event, now's your chance to catch up! youtube.com/playlist?lis...

Swan in a Field. 🦢 #BirdPhotography #Swan #Agriculture #Village #Photography #Binzwangen #Germany

📢 New preprint: Experiment-guided AlphaFold3 resolves accurate protein ensembles. doi.org/10.1101/2025... AlphaFold3 is incredible, but has crucial limitations: it typically collapses to a single conformation, ignoring the inherent dynamics of proteins. And it can be wrong. Here's a solution. 🧵👇

It’s official: ChatGPT can't draw a GPCR, but you’ll master them in the Filizola Lab 😜 Join Us! (send your CV and the names of at least two references to my institutional email) #Postdoc #scientist #research

wikipedia's data shows that AI is siphoning traffic away from the site, which is a danger to its sustainability. ironically Wikipedia is more important than ever to users who want reliable information instead of slop, and to AI companies that need it for training data www.404media.co/wikipedia-sa...

Do you want to invent the future of Chemistry with us? We‘re looking for a "Digital Native” Organic Chemist to join our team at Microsoft Research AI for Science. We offer an amazing environment where you can do deep research with passionate and talented colleagues to solve problems that matter! 1/2

In the early days of quantum chemistry, before we had computers to calculate the shapes of electron orbitals, one man invented a mechanical machine that simulated their shapes. My latest column for @chemistryworld.com www.chemistryworld.com/opinion/the-...

“Mapping ion channel function” doi.org/10.7554/eLif... isn’t exactly a citation slayer, but it’s still one of my favourites (& my first independent project). Today we push pt 2, where we trace code origin & unite almost all channel models in a common expression. Boom! www.biorxiv.org/content/10.1...

I'm on the job market looking for CS/ischool faculty and related positions! I'm broadly interested in doing research with policymakers and communities impacted by AI to inform and develop mitigations to harms and risks. If you've included any of my work in syllabi or policy docs please let me know!

Some flowers from the last days of summer. #Photography #Flowers #Garden

Are you curious about what computational methods can offer to #HPS? Then check out the edited volume by Grant Ramsey & @andreasdeblock.bsky.social, published by @upittpress.bsky.social, showcasing key tools, questions, and investigative perspectives 👇📕💻 upittpress.org/books/978082... #philsky #DH

our new bioRxiv. Light-harvesting by antenna-containing xanthorhodopsin from an Antarctic cyanobacterium www.biorxiv.org/content/10.1...

How visual rhodopsin responds to light in one of nature’s fastest reactions.

#VISTAtalks on #CompChem Wed 15 Oct, 10:00 Buffalo / 16:00 Paris / 22:00 Beijing • Gelin, Hangzhou Dianzi Univ: On-the-fly dynamics → nonlinear spectroscopy via doorway-window • Liu, NYU Shanghai: All-atom nonadiabatic absorption in liquid quantum-dynamics-hub.github.io/VISTA/

The rats don't run this city. The pigeons do. 😉 #Art #Photography #NYC #NewYork

You thought you knew what the Second Law of thermodynamics is? So did I. Researching this piece for @quantamagazine.bsky.social made me realise that I knew only the classical approximation to it. 🤯 www.quantamagazine.org/a-thermomete...

I've put together a tool to renumber antibody structures using only main chain atomic coords. No sequence info is used at all. In the process I found a few numbering mistakes in Sabdab/PDB, which is numbered by sequence & thus sensitive to gaps/register errors (deleted prev post due to bugs)

I'm hiring for a PhD position at Malmö University, Sweden! The project will focus on molecular modelling of proteins, lipids, and biomolecular condensates at cell membranes. More details and application form: tinyurl.com/4zm92365 Please feel free to share! @vetenskapsradet.bsky.social | @mau.se

Join our BioEmu project @msftresearch.bsky.social AI for Science. In Berlin DE or Cambridge UK: aka.ms/bioemu-ml - #MachineLearning Researcher aka.ms/bioemu-data - Data Engineer aka.ms/bioemu-applied - Applied Researcher aka.ms/bioemu-principal - Principal Applied Researcher

Die GDCh schließt sich dem Klimaaufruf von DPG und DMG an: gdch.app/article/gdch...

Werden wir wissenschaftlich abgehängt? Ein Kommentar von Prof. Ulrike Diebold, Vizepräsidentin der österreichischen Akademie der Wissenschaften. Lesenswert!

The Oculus is the main station house of the Port Authority Trans-Hudson (PATH) rapid Transit system which connects Manhattan to New Jersey. It opened on March 3, 2016, as part of the reconstruction of the World Trade Center complex after the 2001 terrorist attacks. #Photography #NewYork #USA

We are looking for 2-3 prospective graduate students to join our group starting the Fall 2026 term. Main projects include method development for ML, MD, drug design, and QM. Please, apply through: lnkd.in/gnM_wC_H

Expanding the family of genetically encoded voltage indicators with a candidate Heliorhodopsin exhibiting near-infrared fluorescence www.sciencedirect.com/science/arti...

Do you like theoretical biology, mathematical&conceptual modelling and want to apply yourself to cutting-edge research at all levels of biology, from molecules to ecosystems? Come to EMBL! Scope includes physics-based models, emergence, statistics, ML/AI embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

View of the #Brooklyn #Skyline from Liberty State Park. #NewYork #Photography

Without its public transit, New York would be little more than a sprawling village. The Transit Museum, located in a former subway station, honors the immense feats of engineering and coordination that keep the city going. #Transit #Subway #Photography #NewYork #NYC #MTA

If you rising senior PhD student and are interested to come to Europe as a postdoc, get in contact with PIs early (6-9 months ahead of time) and discuss postdoc funding options like fellowships

Are the lipids associated with static protein structures there as long-lived ligands or an effect of preferential solvation? This computational-experimental framework shows the way! #lipidtime #compchem www.nature.com/articles/s41...

I am super excited to announce that we have a tenure-track faculty position in biophysics open in the Department of Physics at Carnegie Mellon! 🧪 Interfolio link: apply.interfolio.com/174360 PLEASE, share widely across the blue skies! Let me briefly explain what we're looking for: 1/10

The Temple of Dendur was commissioned around 23 BCE by Emperor Augustus and dedicated to the goddess Isis. It came to the Metropolitan Museum in 1963 as a gift from Egypt after it was removed from its original site for the building of the Aswan Dam. #AncientEgypt #Photography #NewYork #History

Silvia Alonso-Pérez presents a look at the physics behind the theremin, the early electronic musical instrument that converts hand gestures into the eerie tones heard in the soundtracks of classic sci-fi films like The Day the Earth Stood Still. #electronicmusic #physics #acoustics #scifi

This may be the most important paper ever published about NIH funded research. www.science.org/doi/10.1126/...

Molecular fossils may not always be what they seem. “Just as archaeologists know to be careful in how they interpret physical fossils, historians of protein evolution could take similar care in their interpretation of molecular fossils.” - @lynnkamerlin.bsky.social in this co-authored article⤵️

Postdoc position available in the BioEmu team at @msftresearch.bsky.social AI for Science - Berlin DE or Cambridge UK. Looking for candidates with backgrounds in #MachineLearning #AI Biophysics or Bioinformatics jobs.careers.microsoft.com/global/en/jo...

Major cool membrane conference coming up next week! The Biomembrane Days 2025, organized by an amazing team from the MPI for Colloids and Interface Science @mpici.bsky.social: Rumy Dimova (@dimovalab.bsky.social), Helge Ewers, and Thomas Weikl. I'm so very much looking forward to attending! 🤩 🧪

Save the date, my fellow computational alchemists! The upcoming '26 Workshop on Free Energy Methods in Drug Design will be held in Barcelona, Spain, on May 4-6, 2026. The registration link will be sent soon!

Food carts in front of the Metropolitan Museum of Art. #Photography #NewYork #NYC #StreetPhotography