Responses to this work have been great. I want to specifically highlight the contributions of Robert Clark tinyurl.com/5dmm5yns. He started this project as an intern and made it into a rigorous study. He's starting to look for postdocs and I cant recommend him highly enough. Please reach out to him!

We just preprinted one of my favorite studies @FlatironInst . I was lucky to be part of an amazing team studying the effects of rapid cooling to preserve samples in cryoEM. Read on to learn about the limits of cryoEM for biophysics and how to overcome them www.biorxiv.org/content/10.6...

Cannot recommend the talk by Louis Smith enough. It's been such an amazing project!

Really neat math that I use a lot. Well done @pilarcossio.bsky.social, Wai Shing, Jeff and Adi!

It’s been fun to put together and write up cryoJAX. Hooray for open-source cryo-EM software! Now it’s time to use it…

Go use cryojax ! It's awesome! I can't wait to see what people do with it.

Alexandre G. Urzhumtsev: Quantifying distributions of cryo-EM projections ##CryoEM##AngularDistributionOfViews##NonUniformDistribution... ##IUCrhttps://journals.iucr.org/paper?S2059798325011611

The Inaugural Flatiron Institute Cryo-EM Conformational Heterogeneity Challenge pubmed.ncbi.nlm.nih.gov/41280101/ #cryoem

CryoLike: a Python package for cryo-electron microscopy image-to-structure likelihood calculations pubmed.ncbi.nlm.nih.gov/41258998/ #cryoem

Hello world! It's been a true joy to work on this with Michael. Both him and cryoJAX are things to keep an eye on. They're going to make amazing things happen in cryo and beyond.

CryoJAX - A Cryo-Electron Microscopy Image Simulation Library in JAX www.biorxiv.org/content/10.1101/2025.10.23.682564v1 #cryoem

This one is a bit of a departure from the usual and definitely a work in progress! We found that by using ab initio reconstruction at very high res, in very small steps, we could crack some small structures that had eluded us - e.g. 39kDa iPKAc (EMPIAR-10252), below. Read on for details... 1/x

I'm very excited to announce that I've just joined Steve_Bonilla's lab at @rockefelleruniv.bsky.social. With the help of @pilarcossio.bsky.social and colleagues at @flatironinstitute.org. I'll be developing cryoEM into a quantitative method to study RNA biophysics.

The results of the first #cryoEM heterogeneity challenge are up on biorxiv! www.biorxiv.org/content/10.1...

That's a wrap! The results of the first #cryoEM heterogeneity challenge are up on biorxiv! biorxiv.org/content/10.110

Super excited for this one! Great job guys.

That’s a wrap on the 2025 Cold Spring Harbor CryoEM course! Huge thanks to the amazing students for your enthusiasm, the TAs for your dedication, and the invited lecturers for sharing your expertise. Keep pushing the boundaries of single particle EM - excited to see what you all accomplish next!

Watch out world. I can pipette now.

Saturday night and the lab is in full swing as the participants of the CSHL #CryoEM course prepare for the final competition - solve the structure of a mystery protein in less than 4 hours.

Come work in a great place with great people. Loads of fun projects and ideas.

Join leaders from CCDC, ICDD, ICSD, and RCSB PDB on February 12 to learn how data management impacts future research register.gotowebinar...

Super excited to preprint our work on developing a Biomolecular Emulator (BioEmu): Scalable emulation of protein equilibrium ensembles with generative deep learning from @msftresearch.bsky.social ch AI for Science. www.biorxiv.org/content/10.1...

I made a MD starter pack! Dm or reply to be added ☺️☺️ go.bsky.app/QQjPjbL