So lovely to see this story yesterday on SMC complexes presented by Prof Jan Löwe ( MRC LMB). It’s been a long journey and is still evolving but is a structural biology tour de force. @mrclmb.bsky.social @unswbabs.bsky.social

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😳😬 careful folks.

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👏 🧶 🧬 github.com/cytokineking...

🧬🧶 This is a really nice story integrating a number of methods to look at the evolution of a cool protein complex with a focus on protein structure. I love how biology keeps using the same tricks.

Protein people- this is a great conference! Recommended to get your registrations in. 🤩🧬🧶

Today’s paper club: @martinsteinegger.bsky.social @sokrypton.org @milot.bsky.social ( like an all star movie huh?) Looking forward to digging into this one. 🧶🧬

Friday night… 8 pm commute home… feeling like a punk rocker. Don’t forget your task as a scientist. Focus.

😳 Feels awkward being recognised when so many amazing people are behind the scenes in infrastructure development. But it’s good Structural Biology is getting some lime light and support. 🧶🧬 Thanks @brendanburns999.bsky.social

We are proud to announce our newest adventure! Introducing the Diffuse Project, a community-driven effort to predict protein dynamics using the subtle diffuse scattering signal from protein crystals. This collaboration marks a new era for the Ando lab! as.cornell.edu/news/philant... 🧪 🧬🧶 💫

🧬🧶 Useful. Many thanks Alexis.

Current world state: Approaching Ark B status, is it prepped and ready to go? Otherwise it’s a ‘so long and thanks for all the fish’ moment.

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🧬🧶Good opportunity people! Share around.

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Check out this weird protein we found in a Loki Asgard archaea.🧬🧶Only found relatives in other Lokis. 🤔 www.biorxiv.org/content/10.1...

Cool mechanism. 😎🧬🧶 Gotta love protein structure when you see stuff like this.

This was fun! Folding whole proteomes… looking at tomogram, looking at genomes🤩 lots to discover!🧬🧶

Not structure but useful to a lot of protein peeps.🧬🧶

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Last reminder- Dr Rhys Grinter webinar @rhyswg.bsky.social is on in just a couple of hours- click through to obtain the link. #proteindesign #structbiol You can sign up for future event information and reminders here: australian-structural-biology-computing.github.io/website/ 🧶🧬

Hey- anyone at FEMS20205 be sure to stop in to say hi to my amazing PhD student Steffi all the way from Oz🇦🇺! Check out her poster for a cool new Archaeal story- and demonstration of the power of protein structure prediction. Poster session: Section D, Tuesday, 15th July. Poster number: 241.15P 🧬🧶

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😳😱 not a smart move…🧬🧶

Any Protein Cosmos followers. The original feed will shut down in a few days. New feed is up and running- same avatar and name. Still perfecting the search (feed providers are different and have different algorithms). It’s an iterative work in progress. Polite feedback welcome.🧶🧬

Join us on 9 July 2025 for our free webinar 'Exploring macromolecular protein assemblies and their visualisation with @complexportal.bsky.social‬'. Registration is free, but essential: www.ebi.ac.uk/training/eve... Speakers: Sucharitha Balu and Kalpana Panneerselvam | @ebi.embl.org‬ 🧬 🖥️

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ASBC and Biocommons are building opportunities for researchers to discuss and explore protein design tech. First up is @rhyswg.bsky.social. Excited for this!

Australian scientists-Just heard oral abstract submission deadline for ASBMB2025 (being held in Brisbane) has been extended to Monday 7th July. 🧶🧬

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Hello all Protein Cosmos 🧶🧬 followers. A new Protein Cosmos feed had been set up with a new host. You will need to search Protein Cosmos and add the new feed to your account. Apologies and thanks to @blueskyfeeds.com for all their support to get us started. Best luck for the future!

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Anyone following Protein Cosmos just letting you know know the feed provider is unfortunately shutting down the service. I’m working on a solution and hope there won’t be an outage but it is likely that you might have to resubscribe. 🧬🧶 Hang tight…Apologies for the non-proteinacious content.

Great talk today by @carlbergstrom.com at UNSW today about an undergraduate course on using LLMs. Many of the ideas translate to using deep learning tools for protein structure prediction and de novo design. 🧶🧬

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Worth reading peeps… Understanding the metrics, espically their weaknesses is half the game. 🧶🧬

CdpA-an archaeal anchor for FtsZ! Excited to be part of this. (FtsZ is easily my favourite protein and the whole larger family in Archaea are intriguing). www.nature.com/articles/s41...

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Just found out @carlbergstrom.com is talking in my school in a few weeks about “Peer review meltdown”! Very excited!!! @unswbabs.bsky.social

It's great to see NSMB following the lead of IUCr journals like Structural Biology (@actacrystd.iucr.org) and Structural Biology Communications (@actacrystf.iucr.org). Reviewers find it much easier if they don't actually have to ask for the experimental data! Here's hoping other journals follow.

People need to think harder about living forever. If you copy your mind to a neural network eventually it lives on & you do not. It might answer when asked that it is ‘you’, it’s not. Best chance of living longer and with quality is investing in & supporting biomedical science -that’s also vaccines.

Mars is a really poor choice for a campsite… it’s hostile and shitty. Humans, it’s cheaper and a better outcome to work together to solve our problems here on earth where we evolved and that provides our needs than think we can run away to a better place. Science fiction is cool- but it’s fiction.

Another beautiful story from the Master Premee Mohamed. Her usual take on sci fi is dystopian apocalyptic, but it always has a deeply human component. They are clearly shaped by her experience as a molecular scientist. They always hit me in the gut- these days more than they should. Worth reading 😔🖤

Wow.. just… wow 🧶🧬

Check out this new Australian government chamber as the count is coming in! Blue/Liberal should be weeping! And the line from labour in their speeches ‘kindness is not a weakness’.

Australians have voted away from the right. Labour have a monster majority government. Democracy matters here and is respected. Healthcare, education, climate action, all ‘matter’. Albanese’s speech-all about fairness, equality and kindness. Time will tell but good certain mantras were rejected

Read the latest ARDC Connect Newsletter for: 🦈fish & shark data 🎉a new Indigenous language project 🎙️an interview with a research software engineer 🔧tools & services 🔗https://mailchi.mp/ardc.edu.au/1-may-2025 Don't miss another edition: Subscribe Now ✍️https://ardc.edu.au/news-and-events/subscribe/