Matt Baker
@phatmattbaker.bsky.social
π€ 88
π₯ 247
π 15
A/Profπ¬π¨βπ¬ @UNSW π¦π¦πΊ ||
#synbio
#evobio
#biophysics
||
#fencing
π€Ίπ³πΏNZL.
Well done
@laurenceluu.bsky.social
on ASMR Award tonight! Nice talk on pelvic inflammatory disease and great to celebrate
@unswbabs.bsky.social
colleagues' success at NSW Parliament.
#asmr
about 1 month ago
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Well done to Jamiema for your ECR Plenary
#AES2025
yesterday
@unswbabs.bsky.social
A clear talk sharing our enthusiasm for flagellar diversity Uncle Billy welcome to country also awesome. AU has so much biodiversity but also raw human talent in ecology and evolution!
about 2 months ago
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Some absolutely belter talks
#AES2025
in the first macroevolution session. So impressed with the clarity of the talks and beautiful phylogenies and evolutionary narratives. Looking forward to second session after lunch.
about 2 months ago
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@csferrie.com
I thought I was going nuts but you have an error in statistical physics for babies, two of these combinations are the same... There are two combos with a blue and a purple ball on right.
about 2 months ago
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We hoped to control bacteria with light, using LOV domains. Our stators were functional but light didn't impact motility. We then checked if our periplasmic tags could be useful as fluorophores. π Jyoti Gurung for tenacity to get it done πβοΈπ¦πΊβ‘οΈπ¬π§!
doi.org/10.1002/mbo3...
@unswbabs.bsky.social
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Insertion of Fluorescent Proteins Near the Plug Domain of MotB Generates Functional Stator Complexes
We inserted small light-interacting domains at various locations in the stator complex to see what sites were amenable for labeling and how these affected flagellar rotation and switching. We observe...
https://doi.org/10.1002/mbo3.70056
2 months ago
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Our motAB work out now in mBio! We examined the origins of the bacterial flagellar stator βοΈ by combining phylogenetics, ancestral reconstructions, structural predictions and motility assays. Thanks to all authors π³πΏπ¦πΊπΊπΈ
@hfspo.bsky.social
@unswbabs.bsky.social
journals.asm.org/doi/10.1128/...
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Evolution and structural diversity of the MotAB stator: insights into the origins of bacterial flagellar motility | mBio
Flagellar motility allows bacteria to propel themselves and direct movement according to environmental conditions. It plays a key role in bacterial pathogenicity and survival. We investigated the molecular and structural diversity of the stator motor proteins that provide the ion motive force to power flagellar rotation. This study uses a comparative approach that integrates phylogenetics, 3D protein structure, motility assays, and ancestral state reconstruction (ASR) to provide insights into the structural mechanisms that first powered the flagellar motor. We provide the first phylogenetic and structural characterization and classification of MotAB and relatives.
https://journals.asm.org/doi/10.1128/mbio.03824-24
2 months ago
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reposted by
Matt Baker
Human Frontier Science Program
5 months ago
π Programs? Printed. ποΈ Venue? Looking amazing. π§ͺ Energy? Building fast. We're almost ready to welcome the HFSP community to Melbourne for an unforgettable week of science and connection! Who's coming to the 24th HFSP Awardees Meeting?
#HFSP
#HFSPmtg2025
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Nice
@unswbabs.bsky.social
UNSW write up of our paper. βοΈ Melbourne now w/ team to present this and other work at
#HFSP
@hfspo.bsky.social
24th awardee meeting. Looking forward to getting inspired with new biology from interdisciplinary teams across the world.
www.unsw.edu.au/news/2025/06...
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Bacteria were swimming from the start
New analysis shows that the last common ancestor of bacteria had a flagellar motor which enabled it to swim, indicating how important learning to swim was for life.
https://www.unsw.edu.au/news/2025/06/bacteria-were-swimming-from-the-start
5 months ago
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Out this weekend in
@ismepublications.bsky.social
We looked at 10,000 species to map the diversity and history of the bacterial
#flagellar
motor across the tree of life. Lots of (re)analysis , especially from Jamiema Sara Philip
@unswbabs.bsky.social
academic.oup.com/ismej/advanc...
5 months ago
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1st NSW
#fencing
comp of the year β won. Did it with UNSW club and for UNSW. Great to share my experience with current students and see the club in such good health. Impressive student-led self organisation! Otherwise trying to wrap head around
#DECRA
mentoring and imoendinf
#arc
system changes.
9 months ago
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Haven't posted here but here's set of recent wechat posts - last time I logged in at conference zero users here but now more traction. Visit to China and talks at Peking Uni, Westlake Uni and CAS microbiology. Postdoc poster prize for Jacob Scadden in BLAST in Cancun - well done.
10 months ago
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