What a week it's been at the 2026 Lorne Proteins Conference! Centre Director Trevor Lithgow & members of his lab from Monash University attended - showing off their work and taking in the latest research that this important conference showcases. @lorneproteins.bsky.social #lorneproteins2026

Next to @ausbiocommons.bsky.social and @glycojones.bsky.social - good company 😊

Stories from #WomenInScience who changed how we visualize #proteins: Ahead of her 85th birthday, Jane Richardson (Duke Univ, @biophysicalsoc.bsky.social president 2012-13) discussed her life from making a telescope to developing ribbon diagrams for 3D protein structure www.nature.com/articles/s41...

Goodbye Lorne Proteins 2026. An inspiring few days seeing the best of protein science. @lorneproteins.bsky.social

what a brilliant talk! classic Lorne Proteins stuff, getting into how things (in this case Alphafold) works

Thanks to our journal sponsors @febsj.bsky.social and @biochemsoc.bsky.social !! #lorneproteins2026

Closing #lorneproteins2016 😔 🤩 Thanks to our generous sponsors! And for sponsoring our prizes! Speaking of...

Dr Tom Litfin (Australian Biocommons) presented the Structural Biology Platform project and the Australian Computational Structural biology community. If you are interested and missed him you can join up here: australian-structural-biology-computing.github.io/index 🧬🧶 #lorneprotein2026

Last speaker of what’s been a fantastic 2026 Meeting. Hagan Bayley.

Penultimate talk of the meeting by Lauren Porter. Looking at how AlphaFold works under the hood with fold switching proteins.

Wonderful to hear the 2026 #LorneProteins Leach Lecture by Dame Professor Carol Robinson, "Decoding life with mass spectrometry: A lens for biology". Pictured with previous Leach lecturers, @leanntilley.bsky.social (2022) and Frances Separovic (2024).

Honored to be a finalist for the 2026 Blavanik Awards in the UK in Life Sciences. I’m grateful to past and present lab members, collaborators, colleagues and mentors, who made it possible. It’s even better to share this from Vietnam while celebrating the Tet holidays with family.

First speaker. Last session at Lorne Proteins. Michael Hecht on designing proteins for novel functions @lorneproteins.bsky.social

Closing Session 10: Jeanine Amacher | Amino acid variants at the P94 position in S. aureus class A sortase modulate substrate access and activity Position specific regulation of activity. Cat cys recognises short LPXTG Sortase-catalysed ligation Any acyl support! #sortase #lorneproteins2026

Their expertise spans biology, mathematics, statistics, machine learning, AI, computer science and computational modelling. Their collaborative work is bridging disciplines & pushing the boundaries of what we can understand about life at the molecular level! #InternationalDayOfWomenAndGirlsInScience

On the International Day of Women and Girls in Science, MACSYS proudly celebrates the exceptional women who are advancing our mission to model a whole cell - one of the most ambitious challenges in modern science. Pictured here are our Chief Investigators, Research Fellows, and PhD candidates.

Liyu Chen from QBI at UQ talking on her work to probe and cross the blood brain barrier. @lorneproteins.bsky.social

Session 10 - Liyu Chen | JAM-1 nanobody induces barrier weakening and enhanced drug permeability in an in vitro blood-brain barrier-like model Strategies for cerebral drug delivery. #lorneproteins2026

Session 10: Rina Rosenzweig on molecular chaperones, J-domain proteins Most diverse family - 50 different members #lorneproteins2026

Closing Session 9: Tzviya Zeev-Ben-Mordehai on cryoET of the cellular structural biology of mammalian sperm #lorneproteins2026

Session 9: Yu Shang Low - RHS proteins possess YD repeat cages that underlies their functional diversity #lorneproteins2026

Session 9: Kai-En Chen: Structural basis of the membrane-assembled Retromer – Rab7 complex: A molecular timer for vacuolar cargo retrieval #lorneproteins2026

Be part of Lorne Proteins history! Photo session today from 1-1:10 pm. See you there 🎉📷🤩 #lorneproteins2026

First speaker of last day of Lorne Proteins. Arun Shukla on the mechanism of arrestin coupling to GPCRs. @arshukla.bsky.social @lorneproteins.bsky.social

To celebrate #WomenInScience day, @febspress.bsky.social invite you to look at the Women in Science Collection, a selection of articles in FEBS Press, which analyse statistics & challenges together with inspiring role models on gender diversity in #STEM febs.onlinelibrary.wiley.com/doi/toc/10.1...

☕️🫰 Following Session 9 we have a morning tea to celebrate the UNESCO International Day of Women and Girls in Science 🎉, sponsored by Bio21 Platforms! EVERYONE is welcome to celebrate our fabulous Lorne Proteins women in protein science. 🧁🍪💜

Session 9: Arun Shukla on the structure, function and regulation of GPCRs.

We’re hiring: Research Group Leader in computational biology. Are you generating more research ideas than you can explore? Lead cutting-edge AI & biology research at EMBL-EBI. Apply by 11 April 2026: embl.wd103.myworkdayjobs.com/en-US/EMBL/j... #ScienceCareers @ewaldlab.org @embl.org

Emily Furlong (UQ alumnus 😄) talking about her new work on ABC transporters. @emfurlong.bsky.social @lorneproteins.bsky.social

Session 8: The Protein Society Special Lecture - John Kuriyan - Adaptive Capacity of a DNA Polymerase Clamp Loader. Measuring mutagenesis at scale in T4 bacteriophage. T4 del replication machinery. Infects cells, but nothing happens + plasmids with library of replication gene variants...

The IUPAC Global Womens Breakfast 2026 ❤️💛💚💙💜 dawned in Lorne with our first gathering on 10th Feb, concluding with a morning tea on the 11th Feb, meaning we've celebrated across international date lines clear into the UNESCO International Day of Women and Girls in Science! That's commitment!! 💜💚🤍

#lorneproteins2026 resident troublemakers taking a break with a burger on a banksia. Or AI Haiku Galah steals a bite, Banksia perch in Lorne bay, Fast food, feathered friend.

Session 8: David Drew - PfHT1 outside gate is more polar. Shuts more easily. Sugar coordination similar. Allosteric coupling between cargo binding and gating. Many different sugars. ML to take 1000s of AF models and determine conformation state.

The EMBO sponsored member speaker. David Drew on small molecule transporters.

@ansto.bsky.social MX beamline workshop. Bottom lines - match your crystal size to your beamline! Dont shoot a moving target. Wait for the loop position to stabilise. Rasterize to find your xtals. You need training to use MX3! All pins in puck must be the same!!

@ansto.bsky.social thanks for supporting the lightning talks session 7 at #lorneproteins2026 An invigorating pace and excellent variety of subjects! Great session 🤩

S7 ⚡️🌤 Demetra Chatzileontiadou HLAs hold peptides in their pockets APC : T-cell receptor critical HLA - protective or increased pathological outcomes HLA-A*03:01 genetics and covid side effects. How? +Spike epitope xtal structure. Nothing unique...

S7 ⚡️⚡️⚡️⚡️⚡️⚡️⚡️ Adnan Sljoka Probing allostery with computational techniques e.g. GPCRs - NMR, Monte carlo simulations, conf dynamics, how allostery regulates dynamics. Dont forget buried waters!! ms timescales of motion... textbook - rigidity theory: Sublinear computation paradigm #lorneproteins2026

S7 ⚡️⚡️⚡️⚡️⚡️ Hari Venugopal - heavy load Arctica for screening. Can we screen with a lab6 for structure? Biggest problem is drift. Lend me a half mill GATAN Alpine direct electron detector? Yes! ApoF 170 images/hr <3 Å Dose 60. GPCR 1000 images, 50k particles, 4.5 Å structure. #lorneproteins2026

S7 ⚡️⚡️⚡️⚡️ Caroline Puente-Lellevre Bacterial flagellum, an ancient molecular machine. What is the origin of flagellar motility? What is unique about flagellar stators? Computational approach. Larger, 4 or 5 helices - torque generator interacting with the wheel. Cont TM helix, square domain..

S7 ⚡️⚡️⚡️ Neil Robertson - Rational design of a protein motor. A minimal, simple walker. Ligand gated, 3 'feet', tumbleweed on a track. Ligand dependent DBDs in a trimer linked by spycatcher. Speed limit from spr release affinities. 2-3 s. Processivity: how long it stays attached #lorneproteins2026

S7 ⚡️⚡️ Sarah J Piper on GPCR PAC receptor subfamily. Cool animations #blender #molecularnodes #gunforhire PAC1 variants have diverse signalling. Endog activators. VIP signalling on short PAC1? H-bonding networks between peptide and receptors differ with potency. +MD! #lorneproteins2026

S7 ⚡️⚡️ Sarah J Piper on GPCR PAC receptor subfamily. Cool animations #blender #molecularnodes #gunforhire PAC1 variants have diverse signalling. Endog activators. VIP signalling on short PAC1? H-bonding networks between peptide and receptors differ with potency. +MD! #lorneproteins2026

Session 7 ⚡️🌩 talks time!! Jack Zeng Unravelling Promiscuity - OCT1 gating - structures of ligand bound states. Interrogating binding and transport specificity and mechanism. #lorneproteins2026

Closing Session 6: Simon Newstead - Animal to Atom: New avenues for targeting chronic pain. Solute carrier signalling - signaling solute concentrations. Model 1 - e.g. No substrate, lumen ion conc changes. Transporter stabilises, permitting binding TASL, scaffolding its folding. #lorneproteins2026

S6: Renhong Yan - Heteromeric amino acid transporters. Gating mechanism of LAT1-4F2hc complex. Apo, leu, tyr bound states. y+LAT1-4F2hc - Leu import, export Arg; electroneutral 1:1 #lorneproteins2026

A reminder for tomorrow morning - following Session 9 we have a morning tea to celebrate the UNESCO International Day of Women and Girls in Science, sponsored by Bio21 Platforms! Everyone is welcome to celebrate our fabulous Lorne Proteins women in protein science. 🧁🍪

Session 6: Emily Furlong, Structural basis of Ni import by Type I ABC Transporters. 🤫 #lorneproteins2026

Looking forward to sharing our work on the evolution of flagellar proteins! Session 7 - Light-Ning Talks 11am @lorneproteins.bsky.social